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The orthomolecular treatment of cancer II. Clinical trial of high-dose ascorbic acid supplements in advanced human cancer
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“While observational studies using oral and intravenous vitamin C suggested therapeutic benefit for a subset of cancer patients50, 51, 52 subsequent randomized, placebo-controlled trials revealed insignificant efficacy.53, 54”
From Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia (2018) · cites this paper as [50]
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Metadata
- Authors
- Cameron, E., & Campbell, A.
- Affiliations
- Vale of Leven District General Hospital (GB)
- Venue
- Chemico-Biological Interactions
- Publisher
- Elsevier BV
- Published
- 1974-10
- Volume
- 9
- Issue
- 4
- Pages
- 285-315
- ISSN
- 0009-2797 (ISSN-L)
- OpenAlex
- W2011352354
- Cited by
- 344
- References
- 9
- Citations by year
- 2026: 8 · 2025: 9 · 2024: 13 · 2023: 13 · 2022: 21 · 2021: 20 · 2020: 25 · 2019: 19 · 2018: 19 · 2017: 11 · 2016: 14 · 2015: 19 · 2014: 9 · 2013: 10 · 2012: 9
- FWCI
- 5.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemico-Biological Interactions (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Vitamin C and Antioxidants Research
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cancer and biochemical research
- Keywords
- orthomolecular medicine, high-dose ascorbic acid, vitamin C, advanced cancer, palliative care, terminal cancer, cancer supportive care
- MeSH terms
- Administration, Oral, Ascorbic Acid, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Colonic Neoplasms, Dose-Response Relationship, Drug, Drug Evaluation, Drug Stability, Female, Fibrosarcoma, Humans, Injections, Intravenous, Neoplasms, Papilloma, Rectal Neoplasms, Stomach Neoplasms, Time Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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