Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin
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Microtubule affinity has also been employed in the purification of other proteins such as MAP1, tau, and dynein.
“Microtubule affinity has also been employed in the purification of other proteins such as MAP1, tau, and dynein (Vallee and Bloom, 1984; Cleveland et al., 1977; Nasr and Satir, 1985).”
From Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility (1985) · cites this paper as Cleveland et al., 1977
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- Authors
- Cleveland, D. W., Hwo, S.-Y., & Kirschner, M. W.
- Affiliations
- Princeton University (US)
- Venue
- Journal of Molecular Biology
- Publisher
- Elsevier BV
- Published
- 1977-10
- Volume
- 116
- Issue
- 2
- Pages
- 207-225
- ISSN
- 0022-2836 (ISSN-L)
- OpenAlex
- W1971165215
- Cited by
- 915
- References
- 18
- Citations by year
- 2026: 12 · 2025: 19 · 2024: 20 · 2023: 25 · 2022: 24 · 2021: 43 · 2020: 26 · 2019: 29 · 2018: 26 · 2017: 36 · 2016: 20 · 2015: 20 · 2014: 24 · 2013: 16 · 2012: 20
- FWCI
- 11.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Molecular Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Microtubule and mitosis dynamics
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Oncology › Cancer Treatment and Pharmacology
- Keywords
- tau protein, microtubule-associated proteins, tubulin, microtubule assembly, microtubule nucleation, microtubule depolymerization, critical concentration, protein purification, phosphocellulose chromatography, ring structure
- MeSH terms
- Chromatography, Agarose, Electrophoresis, Polyacrylamide Gel, Glycoproteins, Microtubules, Molecular Weight, Proteins, Tubulin
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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