Cited by 76Neuroendocrine regulation and behaviorSexual Differentiation and DisordersStress Responses and Cortisol

Estradiol and parental experience, but not prolactin are necessary for ultrasound recognition and pup-retrieving in the mouse

Koch, Michael, Ehret, Günter·1989·Physiology & Behavior

Abstract

The effects of estradiol, prolactin and experience with pups on pup-retrieving and on the recognition of ultrasonic distress calls of the young by adult ovariectomized female mice were studied. Treatment with estradiol benzoate or experience with pups (for 5 days) induced pup-retrieving in 40% and 60% of the animals, respectively, as compared to 0% in inexperienced ovariectomized females. However, if pup-experience was achieved in the presence of estradiol, retrieving was shown by 90.5% of the animals. In addition, in this case models of the ultrasonic distress calls of the pups were significantly preferred ("recognized") in a discrimination task by the females. These females also showed a sharp increase in serum prolactin concentrations. Depleting prolactin from the blood by cysteamine, however, neither reduced the retrieving score nor disturbed ultrasound recognition. Thus prolactin is dispensable for maintaining maternal pup-retrieving and ultrasound recognition. The process of achieving pup-experience is enhanced by the presence of estradiol. Possible actions of estradiol in the brain are discussed.

Integrity signals

Registry

Crossref · 10.1016/0031-9384(89)90293-x

Cites

63 of 63 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Cohousing virgin females with experienced dams and litters accelerates the onset of maternal behavior.

    “Cohousing virgin females with experienced dams and litters accelerates the onset of maternal behavior”

    From Oxytocin, Neural Plasticity, and Social Behavior (2021) · cites this paper as Koch & Ehret 1989

Cites

Flagged first, then by citations

1 of the 64 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Koch, M., & Ehret, G.
Affiliations
  • University of Konstanz (DE)
  • Universität Ulm (DE)
Venue
Physiology & Behavior
Publisher
Elsevier BV
Published
1989-04
Volume
45
Issue
4
Pages
771-776
ISSN
0031-9384 (ISSN-L)
OpenAlex
W2061302245
Cited by
76
References
64
Citations by year
2026: 1 · 2025: 3 · 2024: 2 · 2023: 5 · 2022: 2 · 2021: 4 · 2020: 1 · 2019: 1 · 2018: 5 · 2017: 2 · 2016: 7 · 2015: 1 · 2014: 4 · 2013: 4 · 2012: 1
FWCI
3.74
Type
journal article
Language
en
Open access
closed
Locations
  • Physiology & Behavior (publishedVersion)
  • PubMed (publishedVersion)
Funders
Deutsche Forschungsgemeinschaft
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords
estradiol, prolactin, maternal behavior, pup retrieval, ovariectomy, estradiol benzoate, cysteamine, parental experiences, female mice
MeSH terms
Animals, Behavior, Animal, Cysteamine, Estradiol, Female, Maternal Behavior, Ovariectomy, Prolactin, Vocalization, Animal, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review