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Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock

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Li, Ping, Allen, Hamish, Banerjee, Subhashis, Franklin, Simon, Herzog, Linda, Johnston, Cynthia, McDowell, Jack, Paskind, Michael, Rodman, Laura, Salfeld, Jochen, Towne, Elizabeth, Tracey, Daniel, Wardwell, Scott, Wei, Feng-Yi, Wong, Winnie, Kamen, Robert, Seshadri, Tara·1995·Cell
DOI 10.1016/0092-8674(95)90490-5
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Research works printed but not linked: 43

  1. Alexander, 1991, A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice, J. Exp. Med., 173, 1029, 10.1084/jem.173.4.1029 · DOI · Paper page
  2. Ayala, 1994, IL-1β converting enzyme is present in monocytic cells as an inactive 45-kDa precursor, J. Immunol., 53, 2592, 10.4049/jimmunol.153.6.2592 · DOI
  3. Black, 1988, Generation of biologically active interleukin-1β by proteolytic cleavage of the inactive precursor, J. Biol. Chem., 263, 9437, 10.1016/S0021-9258(19)76559-4 · DOI · Paper page
  4. Capecchi, 1989, Altering the genome by homologous recombination, Science, 244, 1288, 10.1126/science.2660260 · DOI · Paper page
  5. Car, 1994, Interferon gamma receptor deficient mice are resistant to endotoxic shock, J. Exp. Med., 179, 1437, 10.1084/jem.179.5.1437 · DOI · Paper page
  6. Carruth, 1991, Involvement of a calpain-like protease in the processing of the murine interleukin 1 alpha precursor, J. Biol. Chem., 266, 12162, 10.1016/S0021-9258(18)98874-5 · DOI
  7. Casano, 1994, The structure and complete nucleotide sequence of the murine gene encoding interleukin-1β converting enzyme (ICE), Genomics, 20, 474, 10.1006/geno.1994.1203 · DOI
  8. Cerretti, 1992, Molecular cloning of the interleukin-1β converting enzyme, Science, 256, 97, 10.1126/science.1373520 · DOI · Paper page
  9. Dalton, 1993, Multiple defects of immune cell function in mice with disrupted interferon-gamma genes, Science, 259, 1739, 10.1126/science.8456300 · DOI · Paper page
  10. Dinarello, 1991, Interleukin-1 and interleukin-1 antagonism, Blood, 77, 1627, 10.1182/blood.V77.8.1627.1627 · DOI · Paper page
  11. Dinarello, 1993, The role of interleukin-1 in disease, N. Engl. J. Med., 328, 106, 10.1056/NEJM199301143280207 · DOI · Paper page
  12. Dinarello, 1993, Anticytokine strategies in the treatment of the systemic inflammatory response syndrome, J. Am. Med. Assoc., 269, 1829, 10.1001/jama.1993.03500140081040 · DOI · Paper page
  13. Doetschman, 1985, The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium, J. Embryol. Exp. Morphol., 87, 27
  14. Gagliardini, 1994, Prevention of vertebrate neuronal death by the crmA gene, Science, 263, 826, 10.1126/science.8303301 · DOI · Paper page
  15. Hazuda, 1988, The kinetics of interleukin 1 secretion from activated monocytes. Differences between interleukin 1 alpha and interleukin 1β, J. Biol. Chem., 263, 8473, 10.1016/S0021-9258(18)68502-3 · DOI · Paper page
  16. Howard, 1991, IL-1-converting enzyme requires aspartic acid residues for processing of the IL-1β precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha, J. Immunol., 147, 2964, 10.4049/jimmunol.147.9.2964 · DOI · Paper page
  17. Huang, 1993, Immune response in mice that lack the interferon-gamma receptor, Science, 259, 1742, 10.1126/science.8456301 · DOI · Paper page
  18. Hudig, 1993, Proteases and lymphocyte cytotoxic killing mechanisms, Curr. Opin. Immunol., 5, 90, 10.1016/0952-7915(93)90086-8 · doi:10.1016/0952-7915(93)90086-8
  19. Kopf, 1994, Impaired immune and acute-phase responses in interleukin-6-deficient mice, Nature, 368, 339, 10.1038/368339a0 · DOI · Paper page
  20. Kühn, 1991, Generation and analysis of interleukin-4 deficient mice, Science, 254, 707, 10.1126/science.1948049 · DOI · Paper page
  21. Kühn, 1993, Interleukin-10-deficient mice develop chronic enterocolitis, Cell, 75, 263, 10.1016/0092-8674(93)80068-P · DOI · Paper page
  22. Kumar, 1994, Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme, Genes Dev., 8, 1613, 10.1101/gad.8.14.1613 · DOI · Paper page
  23. Lazebnik, 1994, Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE, Nature, 371, 346, 10.1038/371346a0 · DOI · Paper page
  24. Mansour, 1988, Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes, Nature, 336, 348, 10.1038/336348a0 · DOI · Paper page
  25. Miller, 1993, Purification and characterization of active human interleukin-1β-converting enzyme from THPA monocytic cells, J. Biol. Chem., 268, 18062, 10.1016/S0021-9258(17)46811-6 · DOI
  26. Miura, 1993, Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3, Cell, 75, 653, 10.1016/0092-8674(93)90486-A · DOI · Paper page
  27. Nicoletti, 1991, A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry, J. Immunol. Meth., 139, 271, 10.1016/0022-1759(91)90198-O · DOI · Paper page
  28. Perregaux, 1994, Interleukin-1β maturation and release in response to ATP and nigericin: evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity, J. Biol. Chem., 269, 15195, 10.1016/S0021-9258(17)36591-2 · DOI · Paper page
  29. Ray, 1992, Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme, Cell, 69, 597, 10.1016/0092-8674(92)90223-Y · DOI · Paper page
  30. Rothe, 1993, Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes, Nature, 364, 798, 10.1038/364798a0 · DOI · Paper page
  31. Sadlack, 1993, Ulterative colitis-like disease in mice with a disrupted interleukin-2 gene, Cell, 75, 253, 10.1016/0092-8674(93)80067-O · DOI · Paper page
  32. Schorle, 1991, Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting, Nature, 352, 621, 10.1038/352621a0 · DOI · Paper page
  33. Sentman, 1991, bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes, Cell, 67, 879, 10.1016/0092-8674(91)90361-2 · DOI · Paper page
  34. Sleath, 1990, Substrate specificity of the protease that processes human interleukin-1β, J. Biol. Chem., 265, 14526, 10.1016/S0021-9258(18)77334-1 · DOI
  35. Strange, 1992, Apoptotic cell death and tissue remodelling during mouse mammary gland involution, Development, 115, 49, 10.1242/dev.115.1.49 · DOI · Paper page
  36. Thornberry, 1992, A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes, Nature, 356, 768, 10.1038/356768a0 · DOI · Paper page
  37. Togni, 1994, Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin, Science, 264, 703, 10.1126/science.8171322 · DOI · Paper page
  38. Vaux, 1988, Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells, Nature, 335, 440, 10.1038/335440a0 · DOI · Paper page
  39. Walker, 1994, Crystal structure of the cysteine protease interleukin-1β-converting enzyme: a (p20/p10)2 homodimer, Cell, 78, 343, 10.1016/0092-8674(94)90303-4 · DOI · Paper page
  40. Wang, 1994, Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death, Cell, 78, 739, 10.1016/S0092-8674(94)90422-7 · DOI · Paper page
  41. Wilson, 1994, Structure and mechanism of interleukin-iβ converting enzyme, Nature, 370, 270, 10.1038/370270a0 · DOI · Paper page
  42. Young, 1988, Human interleukin 1β is not secreted from hamster fibroblasts when expressed constitutively from a transfected cDNA, J. Cell. Biol., 107, 447, 10.1083/jcb.107.2.447 · DOI
  43. Yuan, 1993, The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme, Cell, 75, 641, 10.1016/0092-8674(93)90485-9 · DOI · Paper page

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Metadata

Authors
Li, P., Allen, H., Banerjee, S., Franklin, S., Herzog, L., Johnston, C., McDowell, J., Paskind, M., Rodman, L., Salfeld, J., Towne, E., Tracey, D., Wardwell, S., Wei, F.-Y., Wong, W., Kamen, R., & Seshadri, T.
Venue
Cell
Publisher
Elsevier BV
Published
1995-02
Volume
80
Issue
3
Pages
401-411
ISSN
0092-8674 (ISSN-L)
DOI
10.1016/0092-8674(95)90490-5
OpenAlex
W2008261126
Cited by
1,417
References
3
FWCI
41.57
Type
journal article
Language
en
Open access
bronze
Licence

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CoChat. (2026). Citation check: Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. https://app.cochat.ai/papers/10.1016/0092-8674(95)90490-5
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Li, P., Allen, H., Banerjee, S., Franklin, S., Herzog, L., Johnston, C., McDowell, J., Paskind, M., Rodman, L., Salfeld, J., Towne, E., Tracey, D., Wardwell, S., Wei, F.-Y., Wong, W., Kamen, R., & Seshadri, T. (1995). Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell. https://doi.org/10.1016/0092-8674(95)90490-5

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.