Excess mortality of bipolar and unipolar manic-depressive patients
Abstract
To compare mortality in bipolar and unipolar manic-depressive patients, 2168 manic-depressive first admissions reported to the Danish Psychiatric Central Register were divided into a bipolar group (19%), i.e., patients with at least one admission for mania during an average observation period of six years, and a unipolar group. When compared with the general population, the total group had an increased mortality by suicide and accidents in both sexes and by non-violent causes in men. The bipolar group had a higher non-violent mortality than the unipolar group, but the violent mortality was not different. Statistical problems introduced by patients switching from the unipolar to the bipolar group during the period of observation are discussed.
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In the population of bipolar spectrum disorders, deaths from cancer are not higher or only slightly elevated compared with the general population, despite the higher number of risk factors for cancer in this population.
“In the population of bipolar spectrum disorders, deaths from cancer are not higher (8,288,416,417,454-456) or only slightly elevated (417,418,456) compared with the general population, despite the higher number of risk factors for cancer (such as obesity) in this population.”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [456]
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- Authors
- Weeke, A., & Væth, M.
- Affiliations
- Aarhus University Hospital (DK)
- Aarhus University (DK)
- ORCID
- Væth, Michael
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 1986-11
- Volume
- 11
- Issue
- 3
- Pages
- 227-234
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2054796651
- Cited by
- 97
- References
- 16
- Citations by year
- 2025: 1 · 2022: 1 · 2019: 2 · 2016: 1 · 2015: 2 · 2014: 4 · 2013: 2
- FWCI
- 1.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- bipolar disorder, major depressive disorder, excess mortality, suicide, accidental death, violent death, psychiatric inpatients
- MeSH terms
- Accidents, Adolescent, Adult, Aged, Bipolar Disorder, Cardiovascular Diseases, Denmark, Depressive Disorder, Female, Humans, Male, Middle Aged, Neoplasms, Risk, Suicide
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