Suicide, suicidality and suicide prevention in affective disorders
Abstract
Objective: It is well known that functional psychiatric disorders are one of the main causes of suicidal behaviour. This paper discusses the epidemiology and risk factors of suicidal behaviour in affective disorders and goes on to describe the treatment and prevention of such suicidal behaviour. Method: A narrative overview of relevant epidemiological and drug studies. Results: About 60–70% of patients with acute depression experience suicidal ideas. There is a high incidence of suicide (10–15%) in depressive patients. Psychopharmacological treatment with antidepressants and/or mood stabilizers is the most successful approach to avoid the risk of suicidal behaviour. In addition, psychotherapeutic and psychosocial interventions are of importance. Conclusion: Suicidal behaviour and suicide must be considered when treating patients with affective disorders. The complex causation of suicidality has to be borne in mind when considering methods of suicide prevention. In order to obtain the best results, psychosocial, psychotherapeutic and psychopharmacological approaches should be combined, depending on the risk factors of each individual patient.
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Major depressive disorder is associated with higher risk of early death from a broad set of physical disorders and from suicide.
“MDD is also associated with elevated risk of onset, persistence, and severity of a wide range of chronic physical disorders as well as with increased early mortality due to an even wider range of physical disorders and to suicide.”
From The Costs of Depression (2012) · cites this paper as [120]
Major depressive disorder is associated with significantly elevated risk of early death, partly due to high suicide risk and partly due to elevated risk of many physical disorders; it is also associated with elevated mortality risk among people with certain disorders as part of a larger pattern of associations with disorder severity.
“MDD is associated with significantly elevated risk of early death.104, 106, 119 This is true partly because people with MDD have high suicide risk,120–122 but also because depression is associated with elevated risk of the many types of disorders noted above. MDD is also associated with elevated mortality risk among people with certain kinds of disorders as part of a larger pattern of associations”
From The Costs of Depression (2012) · cites this paper as [120]
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- Authors
- Möller, H. J.
- Affiliations
- Ludwig-Maximilians-Universität München (DE)
- Corresponding author
- Möller, H. J.
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 2003-09-04
- Volume
- 108
- Issue
- s418
- Pages
- 73-80
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- OpenAlex
- W1974591192
- Cited by
- 127
- References
- 82
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 6 · 2020: 4 · 2019: 6 · 2018: 4 · 2017: 5 · 2016: 12 · 2015: 7 · 2014: 9 · 2013: 8 · 2012: 4
- FWCI
- 8.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Psychiatrica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- suicide, suicidality, suicide prevention, mood disorders, depression, suicidal ideation, suicide risk factors, antidepressants, mood stabilizers, psychosocial interventions, psychotherapy, combination therapy
- MeSH terms
- Suicide Prevention, Affect, Antidepressive Agents, Clinical Trials as Topic, Humans, Risk Factors, Suicide, Attempted, Incidence, Epidemiologic Studies, Mood Disorders
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