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The role of central oxytocin in obsessive compulsive disorder and related normal behavior
Abstract
Oxytocin (OT) is a neurosecretory nonapeptide synthesized in hypothalamic cells, which project to widely distributed sites in the CNS as well as the neurohypophysis. Central OT affects a variety of cognitive, grooming, affiliative, sexual, and reproductive behaviors in animals. Obsessive Compulsive Disorder (OCD) includes a range of cognitive and behavioral symptoms that bear some relationship to dimensions of behavior associated with OT. Anecdotal data and a recently completed cerebrospinal fluid (CSF) study provide evidence that some forms of OCD are related to OT dysfunction. Based on these findings, we hypothesize: 1) that some forms of OCD are at the extreme end of a range of normal behaviors that are mediated by OT and related systems; and that 2) some normal cognitive, affiliative, and sexual behaviors contain elements that are similar to features of OCD. Alternative hypotheses are considered, and a series of predictions are presented concerning the relationship between central OT and the onset, course, treatment response, and response to challenge procedures seen in this form of OCD.
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“In addition to the actual level of OT in the periphery, the distribution and density of central OT receptors may be another key factor in understanding the role of OT and related neuropeptides in affiliative behavior (70,71).”
From Oxytocin and the development of parenting in humans (2010) · cites this paper as [70]
Citations
Cites
Parallel organization of functionally segregated circuits linking basal ganglia and cortex
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.09.030186.002041 · Cited by 8,527
Purity and Danger: An Analysis of Concepts of Pollution and Taboo
McCormack, W., & Douglas, M. (1967) · Journal for the Scientific Study of Religion · doi:10.2307/1384077 · Cited by 5,738
Purity and Danger: An Analysis of Concepts of Pollution and Taboo.
Ardener, E., & Douglas, M. (1967) · Man · doi:10.2307/2798681 · Cited by 2,824
Hypothalamic integration: organization of the paraventricular and supraoptic nuclei
Swanson, L. W., & Sawchenko, P. E. (1983) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.06.030183.001413 · Cited by 1,991
Gonzalez, R. C., & Mowrer, O. H. (1962) · The American Journal of Psychology · doi:10.2307/1419634 · Cited by 1,584
Swanson, L. W., & Kuypers, H. G. J. M. (1980) · Journal of Comparative Neurology · doi:10.1002/cne.901940306 · Cited by 1,413
Baxter, L. R. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820090009002 · Cited by 1,293
Morris, R. E., Dollard, J., & Miller, N. E. (1951) · The American Catholic Sociological Review · doi:10.2307/3707808 · Cited by 1,226
Abnormal and normal obsessions
Rachman, S., & de Silva, P. (1978) · Behaviour Research and Therapy · doi:10.1016/0005-7967(78)90022-0 · Cited by 1,160
Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat
Buijs, R. M., Swaab, D. F., Dogterom, J., & van Leeuwen, F. W. (1978) · Cell and Tissue Research · doi:10.1007/bf00224932 · Cited by 1,029
Research works printed but not linked: 5
- Charles, 1989, Oxytocin in the treatment of obsessive-compulsive disorder, J Psychiatr Psychol, 4, 111
- Leckman JF, Goodman WK, North WG, Chappell PB, Price LH, Pauls DL, Anderson GM, Riddle MA, McSwiggan-Hardin M, McDougle CJ, Barr LC, Cohen DJ (in press) Elevated levels of CSF oxytocin in obsessive-compulsive disorder. Arch Gen Psychiatry.
- Pauls, 1991, A family study of Tourette's syndrome, Am J Hum Genet, 48, 154
- Rapoport, 1988, Obsessive-compulsive disorder: Is it a basal ganglia dysfunction?, Psychopharmacol Bull, 24, 380
- Richter D, Mohr E (in press) Axonal mRNA transport in the hypothalamo-neurohypophyseal tract of rats. In: North WG, Moses AM, Share L (Eds) The Neurohypophysis: A Window on Brain Function—Annals of the New York Academy of Sciences. The New York Academy of Sciences, New York.
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Gimpl, G., & Fahrenholz, F. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.629 · Cited by 3,089
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Lee, H.-J., Macbeth, A. H., Pagani, J., & Young, W. S. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.04.001 · Cited by 1,037
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Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans
HEINRICHS, M., & DOMES, G. (2008) · Progress in brain research · doi:10.1016/s0079-6123(08)00428-7 · Cited by 479
Oxytocin and the development of parenting in humans
Gordon, I., Zagoory-Sharon, O., Leckman, J. F., & Feldman, R. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.02.005 · Cited by 469
Self-citationEvans, D. W., Leckman, J. F., Carter, A. S., Reznick, J. S., Henshaw, D., King, R. A., & Pauls, D. L. (1997) · Child Development · doi:10.1111/j.1467-8624.1997.tb01925.x · Cited by 449
Self-citationSex differences in oxytocin and vasopressin: Implications for autism spectrum disorders?
CARTER, C. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.025 · Cited by 432
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Chakrabarty, K., Bhattacharyya, S., Christopher, R., & Khanna, S. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300733 · Cited by 344
Mother–infant bonding and the evolution of mammalian social relationships
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Prosocial effects of oxytocin and clinical evidence for its therapeutic potential
Striepens, N., Kendrick, K. M., Maier, W., & Hurlemann, R. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2011.07.001 · Cited by 283
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Leckman, J. F., Grice, D. E., Barr, L. C., de Vries, A. L. C., Martin, C., Cohen, D. J., McDougle, C. J., Goodman, W. K., & Rasmussen, S. A. (1994) · Anxiety · doi:10.1002/anxi.3070010504 · Cited by 263
Self-citationREVIEW: Oxytocin: Crossing the Bridge between Basic Science and Pharmacotherapy
Viéro, C., Shibuya, I., Kitamura, N., Verkhratsky, A., Fujihara, H., Katoh, A., Ueta, Y., Zingg, H. H., Chvátal, A., Syková, E., et al. (2010) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2010.00185.x · Cited by 259
Obsessive-compulsive symptoms in pregnancy and the puerperium:
Abramowitz, J. S., Schwartz, S. A., Moore, K. M., & Luenzmann, K. R. (2003) · Journal of Anxiety Disorders · doi:10.1016/s0887-6185(02)00206-2 · Cited by 242
Neurofunctional mechanisms in autism
Waterhouse, L., Fein, D., & Modahl, C. (1996) · Psychological Review · doi:10.1037/0033-295x.103.3.457 · Cited by 218
Leckman, J. F. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950100030003 · Cited by 209
Self-citationLeckman, J. F., Mayes, L. C., Feldman, R., Evans, D. W., King, R. A., & Cohen, D. J. (1999) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1999.tb10951.x · Cited by 207
Self-citationGender-related clinical differences in obsessive-compulsive disorder
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Neurobiology of the obsessive–compulsive spectrum disorders
Stein, D. J. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00271-1 · Cited by 204
Onset and Exacerbation of Obsessive-Compulsive Disorder in Pregnancy and the Postpartum Period
Forray, A., Focseneanu, M., Pittman, B., McDougle, C. J., & Epperson, C. N. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.09m05381blu · Cited by 155
Self-citationHeterogeneity of obsessive-compulsive disorder: A literature review
Lochner, C., & Stein, D. J. (2003) · Harvard Review of Psychiatry · doi:10.1080/10673220303949 · Cited by 143
The genetics of obsessive compulsive disorder: a review of the evidence
Pauls, D. L. (2008) · American Journal of Medical Genetics Part C: Seminars in Medical Genetics · doi:10.1002/ajmg.c.30168 · Cited by 142
Self-citationObsessive-Compulsive Disorder in Children and Adolescents: A Review
GELLER, D. A., Biederman, J., Jones, J. T., Shapiro, S. J., SCHWARTZ, S., & Park, K. S. (1998) · Harvard Review of Psychiatry · doi:10.3109/10673229809000309 · Cited by 140
The Neurobiology of Social Affiliation and Pair Bonding
Carter, C. S., & Keverne, E. B. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00004-8 · Cited by 130
The orgasmic history of oxytocin: Love, lust, and labor
Magon, N., & Kalra, S. (2011) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.84851 · Cited by 137
The long-term psychiatric and medical prognosis of perinatal mental illness
Meltzer-Brody, S. E., & Stuebe, A. M. (2013) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2013.08.009 · Cited by 124
Dai, L., Carter, C. S., Ying, J., Bellugi, U., Pournajafi-Nazarloo, H., & Korenberg, J. R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038513 · Cited by 119
Strengthening Behavioral Research on Genetic Mental Retardation Syndromes
Hodapp, R. M., & Dykens, E. M. (2001) · American Journal on Mental Retardation · doi:10.1352/0895-8017(2001)106 · Cited by 121
Obsessive-compulsive symptoms during the postpartum period. A prospective cohort.
Miller, E. S., Chu, C., Gollan, J. K., & Gossett, D. R. (2013) · PubMed · Cited by 109
Oxytocin Increases Glucose Uptake in Neonatal Rat Cardiomyocytes
Florian, M., Jankowski, M., & Gutkowska, J. (2009) · Endocrinology · doi:10.1210/en.2009-0624 · Cited by 104
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Martin, A., State, M., Anderson, G. M., Kaye, W. M., Hanchett, J. M., McConaha, C. W., North, W. G., & Leckman, J. F. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00190-5 · Cited by 89
Self-citationFeygin, D. L., Swain, J. E., & Leckman, J. F. (2006) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.01.009 · Cited by 93
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Self-citationPossible role of neuropeptides in obsessive compulsive disorder
McDougle, C. J., Barr, L. C., Goodman, W. K., & Price, L. H. (1999) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00046-8 · Cited by 84
Self-citationGuglielmi, V., Vulink, N. C. C., Denys, D. A. J. P., Wang, Y., SAMUELS, J. F., & Nestadt, G. (2014) · Depression and Anxiety · doi:10.1002/da.22234 · Cited by 83
Leckman, J. F., & Mayes, L. C. (1999) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/s1056-4993(18)30172-x · Cited by 79
Self-citationNormal CSF oxytocin and NPY levels in OCD
Altemus, M. M., Jacobson, K. R., DeBellis, M. D., Kling, M. A., Pigott, T. A., Murphy, D. L., & Gold, P. W. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00263-7 · Cited by 78
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Leckman, J. F., & Mayes, L. C. (1998) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199810000-00010 · Cited by 73
Self-citationMartin, A., State, M. W., Koenig, K. M., Schultz, R. T., Dykens, E., Cassidy, S. B., & Leckman, J. F. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.9.1265 · Cited by 68
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Self-citationKumar, J. R., Rajkumar, R., Jayakody, T., Marwari, S., Hóng, J., Ma, S., Gundlach, A. L., Lai, M. K. P., & Dawe, G. S. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13564 · Cited by 63
Horta, M., Kaylor, K., Feifel, D., & Ebner, N. C. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.10.012 · Cited by 63
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de Mathis, M. A., Diniz, J. B., Shavitt, R. G., Torres, A. R., Ferrão, Y. A., Fossaluza, V., Pereira, C. A. D. B., Miguel, E. C., & do Rosário, M. C. (2009) · CNS Spectrums · doi:10.1017/s1092852900023014 · Cited by 61
Understanding well–being in the evolutionary context of brain development
Keverne, E. B. (2004) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2004.1517 · Cited by 59
Marroni, S. S., Nakano, F., Gati, C. D. C., Oliveira, J. A. C., Antunes‐Rodrigues, J., & Garcia‐Cairasco, N. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002015 · Cited by 55
Rosenberg, D. R., Amponsah, A., Sullivan, A., MacMillan, S. N., & Moore, G. J. (2001) · Journal of Child Neurology · doi:10.1177/088307380101600902 · Cited by 52
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Jenike, M. A. (2001) · Bulletin of the Menninger Clinic · doi:10.1521/bumc.65.1.4.18714 · Cited by 53
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Pauls, D. L., & Alsobrook, J. P. (1999) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/s1056-4993(18)30165-2 · Cited by 51
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Peterson, B. S., Bronen, R. A., & Duncan, C. C. (1996) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.61.5.497 · Cited by 46
Klenerová, V., Krejčı́, I., Sida, P., Hlinak, Z., & Hynie, S. (2009) · PubMed · Cited by 46
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Metadata
- Authors
- Leckman, J. F., Goodman, W. K., North, W. G., Chappell, P. B., Price, L. H., Pauls, D. L., Anderson, G. M., Riddle, M. A., McDougle, C. J., Barr, L. C., & Cohen, D. J.
- Affiliations
- Yale University (US)
- University of Florida Health (US)
- Dartmouth College (US)
- Connecticut Mental Health Center (US)
- Johns Hopkins University (US)
- Corresponding author
- Leckman, James F.
- ORCID
- Venue
- Psychoneuroendocrinology
- Publisher
- Elsevier BV
- Published
- 1994
- Volume
- 19
- Issue
- 8
- Pages
- 723-749
- ISSN
- 0306-4530 (ISSN-L)
- OpenAlex
- W2043814644
- Cited by
- 133
- References
- 211
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 6 · 2020: 1 · 2019: 4 · 2017: 3 · 2016: 11 · 2015: 6 · 2014: 4 · 2013: 5 · 2012: 5
- FWCI
- 1.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychoneuroendocrinology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh044843-03)
- National Institute of Mental Health (MH00508, MH49351, P01MH049351, MH 44843)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- oxytocin, obsessive-compulsive disorder, affiliative behavior, grooming, sexual behavior, normal behavior, treatment response, hypothalamic neurosecretion
- MeSH terms
- Animals, Behavior, Animal, Brain, Brain Mapping, Humans, Hypothalamus, Neural Pathways, Neurophysins, Obsessive-Compulsive Disorder, Oxytocin, Stereotyped Behavior
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