Cited by 88Obsessive-Compulsive Spectrum DisordersNeuroendocrine regulation and behaviorOlfactory and Sensory Function Studies

Intranasal oxytocin in obsessive-compulsive disorder

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Epperson, C. Neill, McDougle, Christopher J., Price, Lawrence H.·1996·Biological Psychiatry

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Crossref · 10.1016/0006-3223(96)00120-5

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14 of 14 references verified0 citation errors · 0 not checkable

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  • A number of studies in healthy people and in patients with psychological or psychiatric disorders show that administration of oxytocin leads to negative not positive social effects, suggesting that exogenous oxytocin does not always lead to increased affiliation.

    “However, a number of studies in healthy people, as well as in patients with psychological or psychiatric disorders show that administration of oxytocin leads to negative not positive social effects (Epperson et al., 1996; Bartz et al., 2011; Feifel, 2011; Mah et al., 2012), suggesting that exogenous oxytocin does not always lead to increased affiliation.”
  • Previous studies have evaluated oxytocin efficacy on more heterogeneous populations (e.g., autism spectrum disorders, obsessive-compulsive disorders) for which the genetic basis has not been established.

    “Previous studies have evaluated OT efficacy on more heterogeneous populations (e.g., autism spectrum disorders, obsessive–compulsive disorders) for which the genetic basis has not been established (Ansseau et al., 1987; den Boer and Westenberg, 1992; Epperson et al., 1996; Guastella et al., 2010; Hollander et al., 2003).”

    From Effects of intranasal oxytocin on social anxiety in males with fragile X syndrome (2012) · cites this paper as Epperson et al., 1996

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Authors
Epperson, C. N., McDougle, C. J., & Price, L. H.
Affiliations
Yale University (US)
Corresponding author
Epperson, C. Neill
Venue
Biological Psychiatry
Publisher
Elsevier BV
Published
1996-09
Volume
40
Issue
6
Pages
547-549
ISSN
0006-3223 (ISSN-L)
OpenAlex
W1971804394
Cited by
88
References
14
Citations by year
2022: 5 · 2020: 4 · 2019: 3 · 2017: 6 · 2016: 7 · 2015: 5 · 2014: 6 · 2013: 10 · 2012: 3
FWCI
2.11
Type
journal article
Language
en
Open access
Locations
  • Biological Psychiatry (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (T32 MH18268, P01 MH25642, P01MH025642, T32MH018268)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
Keywords
intranasal oxytocin, obsessive-compulsive disorder, oxytocin, treatment-resistant OCD
MeSH terms
Administration, Intranasal, Double-Blind Method, Female, Humans, Male, Middle Aged, Obsessive-Compulsive Disorder, Oxytocin, Cross-Over Studies

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