Intranasal oxytocin in obsessive-compulsive disorder
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A number of studies in healthy people and in patients with psychological or psychiatric disorders show that administration of oxytocin leads to negative not positive social effects, suggesting that exogenous oxytocin does not always lead to increased affiliation.
“However, a number of studies in healthy people, as well as in patients with psychological or psychiatric disorders show that administration of oxytocin leads to negative not positive social effects (Epperson et al., 1996; Bartz et al., 2011; Feifel, 2011; Mah et al., 2012), suggesting that exogenous oxytocin does not always lead to increased affiliation.”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Epperson et al., 1996
Previous studies have evaluated oxytocin efficacy on more heterogeneous populations (e.g., autism spectrum disorders, obsessive-compulsive disorders) for which the genetic basis has not been established.
“Previous studies have evaluated OT efficacy on more heterogeneous populations (e.g., autism spectrum disorders, obsessive–compulsive disorders) for which the genetic basis has not been established (Ansseau et al., 1987; den Boer and Westenberg, 1992; Epperson et al., 1996; Guastella et al., 2010; Hollander et al., 2003).”
From Effects of intranasal oxytocin on social anxiety in males with fragile X syndrome (2012) · cites this paper as Epperson et al., 1996
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- Authors
- Epperson, C. N., McDougle, C. J., & Price, L. H.
- Affiliations
- Yale University (US)
- Corresponding author
- Epperson, C. Neill
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 1996-09
- Volume
- 40
- Issue
- 6
- Pages
- 547-549
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W1971804394
- Cited by
- 88
- References
- 14
- Citations by year
- 2022: 5 · 2020: 4 · 2019: 3 · 2017: 6 · 2016: 7 · 2015: 5 · 2014: 6 · 2013: 10 · 2012: 3
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Biological Psychiatry (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (T32 MH18268, P01 MH25642, P01MH025642, T32MH018268)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Keywords
- intranasal oxytocin, obsessive-compulsive disorder, oxytocin, treatment-resistant OCD
- MeSH terms
- Administration, Intranasal, Double-Blind Method, Female, Humans, Male, Middle Aged, Obsessive-Compulsive Disorder, Oxytocin, Cross-Over Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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