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Exercise and the Regulation of Immune Functions
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Cites
Physical activity and immune function in elderly women
NIEMAN, D. C., HENSON, D. A., GUSEWITCH, G., WARREN, B. J., DOTSON, R. C., BUTTERWORTH, D. E., & NEHLSEN-CANNARELLA, S. L. (1993) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199307000-00011 · Cited by 393
Exercise and the aging immune system
Simpson, R. J., Lowder, T. W., Spielmann, G., Bigley, A. B., LaVoy, E. C., & Kunz, H. (2012) · Ageing Research Reviews · doi:10.1016/j.arr.2012.03.003 · Cited by 281
Self-citationIncidence, Etiology, and Symptomatology of Upper Respiratory Illness in Elite Athletes
SPENCE, L., BROWN, W. J., PYNE, D. B., NISSEN, M. D., SLOOTS, T. P., MCCORMACK, J. G., LOCKE, A. S., & FRICKER, P. A. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31802e851a · Cited by 275
Exercise-induced muscle-derived cytokines inhibit mammary cancer cell growth
Hojman, P., Dethlefsen, C., Brandt, C., Hansen, J., Pedersen, L., & Pedersen, B. K. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00520.2010 · Cited by 259 · cited 1×
“Moreover, many studies done in animals have also revealed positive effects of moderate intensity exercise training on immune responses and outcomes to viral infections and cancer.(81,82) Hallmark features of immunosenescence include an inverted CD4+/CD8+ T-cell ratio and an increased frequency and proportion of senesc…”
BackgroundIL-7 is expressed and secreted by human skeletal muscle cells
Haugen, F., Norheim, F., Lian, H., Wensaas, A. J., Dueland, S., Berg, O., Funderud, A., Skålhegg, B. S., Raastad, T., & Drevon, C. A. (2010) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00094.2009 · Cited by 237 · cited 1×
“In both mice and humans, IL-7 therapy has been shown to increase thymic mass and activity,(84) and exercise, in turn, has been shown to increase plasma levels of IL-7(85) that is most likely released by contracting skeletal muscle.(86) Thus, exercise may play an instrumental role in the acquisition of “new recruits,”…”
BackgroundAcute exercise mobilises CD8+ T lymphocytes exhibiting an effector-memory phenotype
Campbell, J. P., Riddell, N. E., Burns, V. E., Turner, M., van Zanten, J. J. C. S. V., Drayson, M. T., & Bosch, J. A. (2009) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2009.02.011 · Cited by 220
Aerobic fitness is associated with lower proportions of senescent blood T-cells in man
Spielmann, G., McFarlin, B. K., O’Connor, D. P., Smith, P. J. W., Pircher, H., & Simpson, R. J. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2011.07.226 · Cited by 180
Self-citationLancaster, G., Halson, S., Khan, Q., Drysdale, P., Wallace, F., Jeukendrup, A., Drayson, M., & Gleeson, M. (2026) · Exercise Immunology Review · doi:10.22029/eir.2004.1608 · Cited by 159
Pascoe, A. R., Fiatarone Singh, M. A., & Edwards, K. M. (2014) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2013.10.003 · Cited by 149
Peake, J., Wilson, G., Hordern, M., Suzuki, K., Yamaya, K., Nosaka, K., Mackinnon, L., & Coombes, J. S. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01331.2003 · Cited by 105
Cited by
The compelling link between physical activity and the body's defense system
Nieman, D. C., & Wentz, L. M. (2019) · Journal of Sport and Health Science · doi:10.1016/j.jshs.2018.09.009 · Cited by 1,340
PATEL, A. V., FRIEDENREICH, C. M., MOORE, S. C., HAYES, S. C., SILVER, J. K., CAMPBELL, K. L., WINTERS-STONE, K., GERBER, L. H., GEORGE, S. M., FULTON, J. E., et al. (2019) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002117 · Cited by 861
Schwellnus, M., Soligard, T., Alonso, J.-M., Bahr, R., Clarsen, B., Dijkstra, H. P., Gabbett, T. J., Gleeson, M., Hägglund, M., Hutchinson, M. R., et al. (2016) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-096572 · Cited by 836
Skeletal Muscle as Potential Central Link between Sarcopenia and Immune Senescence
Nelke, C., Dziewas, R., Minnerup, J., Meuth, S. G., & Ruck, T. (2019) · eBioMedicine · doi:10.1016/j.ebiom.2019.10.034 · Cited by 437
Crucian, B. E., Choukèr, A., Simpson, R. J., Mehta, S., Marshall, G., Smith, S. M., Zwart, S. R., Heer, M., Ponomarev, S., Whitmire, A., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01437 · Cited by 421
Self-citationExploring the Role of Neuroplasticity in Development, Aging, and Neurodegeneration
Marzola, P., Melzer, T., Pavesi, E., Gil-Mohapel, J., & Brocardo, P. S. (2023) · Brain Sciences · doi:10.3390/brainsci13121610 · Cited by 281
Exercise sustains the hallmarks of health
Qiu, Y., Fernández-García, B., Lehmann, H. I., Li, G., Kroemer, G., López-Otín, C., & Xiao, J. (2023) · Journal of Sport and Health Science · doi:10.1016/j.jshs.2022.10.003 · Cited by 270
Graff, R. M., Kunz, H. E., Agha, N. H., Baker, F. L., Laughlin, M., Bigley, A. B., Markofski, M. M., LaVoy, E. C., Katsanis, E., Bond, R. A., et al. (2018) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.08.017 · Cited by 145
Self-citationExercise as adjunct therapy in cancer
Ashcraft, K. A., Warner, A. B., Jones, L. W., & Dewhirst, M. W. (2019) · Seminars in Radiation Oncology · doi:10.1016/j.semradonc.2018.10.001 · Cited by 148
Ezzatvar, Y., Ramírez-Vélez, R., Izquierdo, M., & Garcia-Hermoso, A. (2022) · British Journal of Sports Medicine · doi:10.1136/bjsports-2022-105733 · Cited by 86
Treating depression With Tai Chi: state of the art and future perspectives
Kong, J., Wilson, G., Park, J., Pereira, K., Walpole, C., & Yeung, A. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00237 · Cited by 75
Chu, A., Holdaway, C., Varma, T., Petocz, P., & Samman, S. (2018) · Sports Medicine · doi:10.1007/s40279-017-0818-8 · Cited by 44
Glucocorticoids and natural killer cells: A suppressive relationship
Muscari, I., Fierabracci, A., Adorisio, S., Moretti, M., Cannarile, L., Thi Minh Hong, V., Ayroldi, E., & Delfino, D. V. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.114930 · Cited by 32
Zhang, T., & Kong, J. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1567603 · Cited by 19
The impact of exercise on patients with dementia: A 2-year follow-up
Chen, K.-H., Chen, H.-H., Li, L., Lin, H.-C., Chen, C.-L., & Chen, N.-C. (2020) · Medicine · doi:10.1097/md.0000000000020597 · Cited by 13
Effects on Spirulina Supplementation on Immune Cells’ Parameters of Elite College Athletes
Zhang, Y., Zhang, Y., Wu, W., Xu, Y., Li, X., Qiu, Q., & Chen, H. (2022) · Nutrients · doi:10.3390/nu14204346 · Cited by 10
Metadata
- Authors
- Simpson, R. J., Kunz, H., Agha, N., & Graff, R.
- Venue
- Progress in Molecular Biology and Translational Science
- Publisher
- Elsevier
- Published
- 2015
- Volume
- 135
- Pages
- 355-380
- ISSN
- 1877-1173 (ISSN-L)
- OpenAlex
- W2112141400
- Cited by
- 602
- References
- 11
- FWCI
- 58.89
- Type
- book chapter
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
