Cited by 892Characterization and Applications of Magnetic NanoparticlesNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics

The DOI matches its Crossref record; 93 of the 94 references it cites were found in a registry or an index, and 1 are not checked yet.

Multifunctional magnetic nanoparticles for targeted imaging and therapy

Open access

MCCARTHY, J, WEISSLEDER, R·2008·Advanced Drug Delivery Reviews

DOI 10.1016/j.addr.2008.03.014PMC PMC2583936

Open this paper in CoChat — free account

Abstract

Magnetic nanoparticles have become important tools for the imaging of prevalent diseases, such as cancer, atherosclerosis, diabetes, and others. While first generation nanoparticles were fairly nonspecific, newer generations have been targeted to specific cell types and molecular targets via affinity ligands. Commonly, these ligands emerge from phage or small molecule screens, or are based on antibodies or aptamers. Secondary reporters and combined therapeutic molecules have further opened potential clinical applications of these materials. This review summarizes some of the recent biomedical applications of these newer magnetic nanomaterials.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.addr.2008.03.014

Cites

93 of 94 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Inflammation, Atherosclerosis, and Coronary Artery Disease
Hansson, G. K. (2005) · New England Journal of Medicine · doi:10.1056/nejmra043430 · Cited by 8,773
Inflammation in atherosclerosis
Libby, P. (2002) · Nature · doi:10.1038/nature01323 · Cited by 8,315
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
Maeda, H., Wu, J., Sawa, T., Matsumura, Y., & Hori, K. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00248-5 · Cited by 6,565
Cancer nanotechnology: opportunities and challenges
Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558
Inflammation in Atherosclerosis
Libby, P. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.179705 · Cited by 3,796
Applications of Magnetic Nanoparticles in Biomedicine
Bárcena, C., Sra, A. K., & Gao, J. (2009) · Springer eBooks · doi:10.1007/978-0-387-85600-1_20 · Cited by 2,571
The immune response in atherosclerosis: a double-edged sword
Hansson, G. K., & Libby, P. (2006) · Nature reviews. Immunology · doi:10.1038/nri1882 · Cited by 2,220
Noninvasive detection of clinically occult lymph-node metastases in prostate cancer
Harisinghani, M. G., Barentsz, J., Hahn, P. F., Deserno, W. M., Tabatabaei, S., van de Kaa, C. H., de la Rosette, J., & Weissleder, R. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022749 · Cited by 1,971
Self-citation
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
Lewin, M., Carlesso, N., Tung, C., Tang, X. S., Cory, D. G., Scadden, D. T., & Weissleder, R. (2000) · Nature Biotechnology · doi:10.1038/74464 · Cited by 1,716
Self-citation
Delineation of prognostic biomarkers in prostate cancer
Dhanasekaran, S. M., Barrette, T. R., Ghosh, D., Shah, R. B., Varambally, S., Kurachi, K., Pienta, K. J., Rubin, M. A., & Chinnaiyan, A. M. (2001) · Nature · doi:10.1038/35090585 · Cited by 1,675

Flagged first, then by citations

Show all 92 references

Sorted by citations

Items 201–300 of 890

Fast processes of nanoparticle blood clearance: Comprehensive study
Zelepukin, I. V., Yaremenko, A. V., Yuryev, M. V., Mirkasymov, A. B., Sokolov, I. L., Deyev, S. M., Nikitin, P. I., & Nikitin, M. P. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.07.014 · Cited by 94
Iron oxide/manganese oxide co-loaded hybrid nanogels as pH-responsive magnetic resonance contrast agents
Wang, X., Niu, D., Wu, Q., Bao, S., Su, T., Liu, X., Zhang, S., & Wang, Q. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.02.101 · Cited by 93
Functional Nanoparticles in Targeting Glioma Diagnosis and Therapies
Li, M., Deng, H., Peng, H., & Wang, Q. (2014) · Journal of Nanoscience and Nanotechnology · doi:10.1166/jnn.2014.8757 · Cited by 92
Nanotoxicology: Advances and Pitfalls in Research Methodology
Azhdarzadeh, M., Saei, A. A., Sharifi, S., Hajipour, M. J., Alkilany, A. M., Sharifzadeh, M., Ramazani, F., Laurent, S., Mashaghi, A., & Mahmoudi, M. (2015) · Nanomedicine · doi:10.2217/nnm.15.130 · Cited by 96
A starch-based stimuli-responsive magnetite nanohydrogel as de novo drug delivery system
Massoumi, B., Mozaffari, Z., & Jaymand, M. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.05.211 · Cited by 91
Multifunctional Ag@Fe2O3 yolk–shell nanoparticles for simultaneous capture, kill, and removal of pathogen
Wei, Z., Zhou, Z., Yang, M., Lin, C., Zhao, Z., Huang, D., Chen, Z., & Gao, J. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm13691g · Cited by 90
Kanamycin detection based on the catalytic ability enhancement of gold nanoparticles
Wang, C., Chen, D., Wang, Q., & Tan, R. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.12.042 · Cited by 89
Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis
Allawadhi, P., Singh, V., Govindaraj, K., Khurana, I., Sarode, L. P., Navik, U., Banothu, A. K., Weiskirchen, R., Bharani, K. K., & Khurana, A. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.118923 · Cited by 90
In vitro and in vivo experiments with iron oxide nanoparticles functionalized with DEXTRAN or polyethylene glycol for medical applications: Magnetic targeting
Mojica Pisciotti, M. L., Lima, E., Vasquez Mansilla, M., Tognoli, V. E., Troiani, H. E., Pasa, A. A., Creczynski‐Pasa, T. B., Silva, A. H., Gurman, P., Colombo, L., et al. (2014) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.33068 · Cited by 87
New advances strategies for surface functionalization of iron oxide magnetic nano particles (IONPs)
Nosrati, H., Salehiabar, M., Davaran, S., Ramazani, A., Manjili, H. K., & Danafar, H. (2017) · Research on Chemical Intermediates · doi:10.1007/s11164-017-3084-3 · Cited by 86
Multifunctional Nanocarpets for Cancer Theranostics: Remotely Controlled Graphene Nanoheaters for Thermo-Chemosensitisation and Magnetic Resonance Imaging
Sasikala, A. R. K., Thomas, R. G., Unnithan, A. R., Saravanakumar, B., Jeong, Y. Y., Park, C. H., & Kim, C. S. (2016) · Scientific Reports · doi:10.1038/srep20543 · Cited by 86
Rapid and specific influenza virus detection by functionalized magnetic nanoparticles and mass spectrometry
Chou, T., Hsu, W., Wang, C., Chen, Y., & Fang, J. (2011) · Journal of Nanobiotechnology · doi:10.1186/1477-3155-9-52 · Cited by 86
Superhigh-magnetization nanocarrier as a doxorubicin delivery platform for magnetic targeting therapy
Hua, M., Yang, H., Liu, H.-L., Tsai, R., Pang, S., Chuang, K., Chang, Y., Hwang, T., Chang, Y., Chuang, H., et al. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.08.014 · Cited by 85
PEGylated FePt@Fe2O3 core-shell magnetic nanoparticles: Potential theranostic applications and in vivo toxicity studies
Liu, Y., Yang, K., Cheng, L., Zhu, J., Ma, X., Xu, H., Li, Y., Guo, L., Gu, H., & Liu, Z. (2013) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2013.02.010 · Cited by 85
Recent Advances in Gadolinium Based Contrast Agents for Bioimaging Applications
Fatima, A., Ahmad, M. W., Saidi, A. K. A. A., Choudhury, A., Chang, Y., & Lee, G. H. (2021) · Nanomaterials · doi:10.3390/nano11092449 · Cited by 86
Magnetic nanoparticles as contrast agents in biomedical imaging: recent advances in iron- and manganese-based magnetic nanoparticles
Felton, C. M., Karmakar, A., Gartia, Y., Ramidi, P., Biris, A. S., & Ghosh, A. (2014) · Drug Metabolism Reviews · doi:10.3109/03602532.2013.876429 · Cited by 87
Peptide- and saccharide-conjugated dendrimers for targeted drug delivery: a concise review
Liu, J., Gray, W. D., Davis, M. E., & Luo, Y. (2012) · Interface Focus · doi:10.1098/rsfs.2012.0009 · Cited by 85
Application of nanoparticles on diagnosis and therapy in gliomas.
Hernández-Pedro, N. Y., Rangel-López, E., Magaña-Maldonado, R., de la Cruz, V. P., Santamaría del Angel, A., Pineda, B., & Sotelo, J. (2013) · BioMed Research International · doi:10.1155/2013/351031 · Cited by 84
Design and Fabrication of Magnetically Responsive Nanocarriers for Drug Delivery
Kralj, S., Potrč, T., Kocbek, P., Marchesan, S., & Makovec, D. (2016) · Current Medicinal Chemistry · doi:10.2174/0929867323666160813211736 · Cited by 84
Dilemmas in the reliable estimation of the in-vitro cell viability in magnetic nanoparticle engineering: which tests and what protocols?
Hoskins, C., Wang, L., Cheng, W. P., & Cuschieri, A. (2012) · Nanoscale Research Letters · doi:10.1186/1556-276x-7-77 · Cited by 88
MR imaging and targeting of a specific alveolar macrophage subpopulation in LPS-induced COPD animal model using antibody-conjugated magnetic nanoparticles
Al Faraj, A., Sultana Shaik, A., Afzal, S., Al Sayed, B., & Halwani, R. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s59394 · Cited by 83
Magnetically Decorated Multiwalled Carbon Nanotubes as Dual MRI and SPECT Contrast Agents
Wang, J. T.-W., Cabana, L., Bourgognon, M., Kafa, H., Protti, A., Venner, K., Shah, A. M., Sosabowski, J. K., Mather, S. J., Roig, A., et al. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201302892 · Cited by 85
Tumor Penetrating Theranostic Nanoparticles for Enhancement of Targeted and Image-guided Drug Delivery into Peritoneal Tumors following Intraperitoneal Delivery
Gao, N., Bozeman, E. N., Qian, W., Wang, L., Chen, H., Lipowska, M., Staley, C. A., Wang, Y. A., Mao, H. Z., & Yang, L. P. H. (2017) · Theranostics · doi:10.7150/thno.18125 · Cited by 83
Nanoparticles functionalised with recombinant single chain Fv antibody fragments (scFv) for the magnetic resonance imaging of cancer cells
Vigor, K., Kyrtatos, P. G., Minogue, S., Al‐Jamal, K. T., Kogelberg, H., Tolner, B., Kostarelos, K., Beǵent, R. H. J., Pankhurst, Q. A., Lythgoe, M. F., et al. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.10.036 · Cited by 83
Poly-l-lysine-coated magnetic nanoparticles as intracellular actuators for neural guidance.
Raffa, V., Riggio, C., Calatayud, Hoskins, Pinkernelle, Goya, Wang, L., Keilhoff, & Cuschieri, A. (2012) · International Journal of Nanomedicine · doi:10.2147/ijn.s28460 · Cited by 83
Combining ultrasmall gadolinium-based nanoparticles with photon irradiation overcomes radioresistance of head and neck squamous cell carcinoma
Miladi, I., Aloy, M., Armandy, E., Mowat, P., Kryza, D., Magné, N., Tillement, O., Lux, F., Billotey, C., Janier, M. F., et al. (2014) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2014.06.013 · Cited by 80
Particle-by-Particle Charge Analysis of DNA-Modified Nanoparticles Using Tunable Resistive Pulse Sensing
Blundell, E. L. C. J., Vogel, R., & Platt, M. (2016) · Langmuir · doi:10.1021/acs.langmuir.5b03024 · Cited by 80
Effect of reaction time on structural and magnetic properties of green-synthesized magnetic nanoparticles
Karade, V. C., Dongale, T. D., Sahoo, S. C., Kollu, P., Chougale, A. D., Patil, P., & Patil, P. B. (2018) · Journal of Physics and Chemistry of Solids · doi:10.1016/j.jpcs.2018.04.040 · Cited by 80
Novel Molecular and Nanosensors for In Vivo Sensing
Eckert, M. A., Vu, P., Zhang, K., Kang, D., Ali, M. M., Xu, C., & Zhao, W. (2013) · Theranostics · doi:10.7150/thno.6584 · Cited by 79
Aptamers as targeting ligands and therapeutic molecules for overcoming drug resistance in cancers
Zhou, G., Latchoumanin, O., Hebbard, L., Duan, W., Liddle, C., George, J., & Qiao, L. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.04.005 · Cited by 80
Imaging applications of nanotechnology in cancer
Gunasekera, U. A., Pankhurst, Q. A., & Douek, M. (2009) · Targeted Oncology · doi:10.1007/s11523-009-0118-9 · Cited by 77
Long-term theranostic hydrogel system for solid tumors
Kim, J. I., Lee, B. S., Chun, C., Cho, J.-K., Kim, S.-Y., & Song, S. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.11.083 · Cited by 78
Targeted nanocarriers for imaging and therapy of vascular inflammation
Chacko, A., Hood, E. D., Zern, B. J., & Muzykantov, V. R. (2011) · Current Opinion in Colloid & Interface Science · doi:10.1016/j.cocis.2011.01.008 · Cited by 76
Amine‐surface‐modified superparamagnetic iron oxide nanoparticles interfere with differentiation of human mesenchymal stem cells
Chang, Y., Liu, Y., Ho, J. H., Hsu, S., & Lee, O. K. (2012) · Journal of Orthopaedic Research® · doi:10.1002/jor.22088 · Cited by 76
Targeted near-IR hybrid magnetic nanoparticles for in vivo cancer therapy and imaging
Kirui, D. K., Khalidov, I., Wang, Y., & Batt, C. A. (2012) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2012.11.009 · Cited by 76
New Frontiers in Molecular Imaging with Superparamagnetic Iron Oxide Nanoparticles (SPIONs): Efficacy, Toxicity, and Future Applications
Frantellizzi, V., Conte, M., Pontico, M., Pani, A., Pani, R., & Vincentis, G. D. (2020) · Nuclear Medicine and Molecular Imaging · doi:10.1007/s13139-020-00635-w · Cited by 78
Therapeutic use of monoclonal antibodies: general aspects and challenges for drug delivery
Quinteros, D. A., Bermúdez, J. M., Ravetti, S., Cid, A. G., Allemandi, D. A., & Palma, S. D. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-46143-6.00025-7 · Cited by 86
Synthesis, characterization and toxicological evaluation of iron oxide nanoparticles in human lung alveolar epithelial cells
Dwivedi, S., Siddiqui, M. A., Farshori, N. N., Ahamed, M., Musarrat, J., & Al-Khedhairy, A. A. (2014) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2014.06.064 · Cited by 75
Aptamer conjugated magnetic nanoparticles as nanosurgeons
Nair, B. G., Nagaoka, Y., Morimoto, H., Yoshida, Y., Maekawa, T., & Kumar, D. S. (2010) · Nanotechnology · doi:10.1088/0957-4484/21/45/455102 · Cited by 75
Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug
Krishnan, P., Rajan, M., Kumari, S., Sakinah, S., Priya, S. P., Amira, F., Danjuma, L., Ling, M. P., Fakurazi, S., Arulselvan, P., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-09140-1 · Cited by 75
Facile Synthetic Route for Surface-Functionalized Magnetic Nanoparticles: Cell Labeling and Magnetic Resonance Imaging Studies
Chung, H. J., Lee, H., Bae, K. H., Lee, Y., Park, J., Cho, S., Hwang, J. Y., Park, H., Langer, R., Anderson, D. G., et al. (2011) · ACS Nano · doi:10.1021/nn201198f · Cited by 76
Cellular interaction of folic acid conjugated superparamagnetic iron oxide nanoparticles and its use as contrast agent for targeted magnetic imaging of tumor cells
Dinda, A. K., Kumar, M., Singh, Arora, Mewar, Sharma, Jagannathan, N. R., Sapra, S., Dinda, A. K., Kharbanda, et al. (2012) · International Journal of Nanomedicine · doi:10.2147/ijn.s32694 · Cited by 74
Targeted nanoparticles for image‐guided treatment of triple‐negative breast cancer: clinical significance and technological advances
Miller‐Kleinhenz, J. M., Bozeman, E. N., & Yang, L. P. H. (2015) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1343 · Cited by 73
Iron oxide nanoparticles as magnetic relaxation switching (MRSw) sensors: Current applications in nanomedicine
Alcántara, D., Lopez, S., García‐Martín, M. L., & Pozo, D. (2016) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2016.01.005 · Cited by 74
The Effects of Physicochemical Properties of Nanomaterials on Their Cellular Uptake In Vitro and In Vivo
Liu, Y., Workalemahu, B., & Jiang, X. (2017) · Small · doi:10.1002/smll.201701815 · Cited by 74
Applying gold nanoparticles as tumor-vascular disrupting agents during brachytherapy: estimation of endothelial dose enhancement
Ngwa, W. F., Makrigiorgos, G. M., & Berbeco, R. I. (2010) · Physics in Medicine and Biology · doi:10.1088/0031-9155/55/21/013 · Cited by 72
Targeted nanoagents for the detection of cancers
McCarthy, J. R., Bhaumik, J., Karver, M. R., Erdem, S. S., & Weissleder, R. (2010) · Molecular Oncology · doi:10.1016/j.molonc.2010.08.003 · Cited by 72
Self-citation
Monolayer grafting of aminosilane on magnetic nanoparticles: An efficient approach for targeted drug delivery system
Dhavale, R. P., Waifalkar, P. P., Sharma, A., Dhavale, R. P., Sahoo, S. C., Kollu, P., Chougale, A. D., Zahn, D. R. T., Salvan, G., Patil, P., et al. (2018) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2018.06.006 · Cited by 72
Facile surfactant-free synthesis and characterization of Fe 3 O 4 @3-aminophenol–formaldehyde core–shell magnetic microspheres
Zhao, J., Luque, R., Qi, W., Lai, J., Gao, W., Gilani, M. R. H. S., & Xu, G. (2014) · Journal of Materials Chemistry A · doi:10.1039/c4ta03821e · Cited by 71
Cells as Factories for Humanized Encapsulation
Mao, Z., Cartier, R., Hohl, A., Farinacci, M., Dorhoi, A., Nguyen, T., Mulvaney, P. A., Ralston, J., Kaufmann, S. H. E., Möhwald, H., et al. (2011) · Nano Letters · doi:10.1021/nl200801n · Cited by 68
Multifunctional agents for concurrent imaging and therapy in cardiovascular disease
McCarthy, J. R. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.07.004 · Cited by 73
Self-citation
Bio-Catalysis and Biomedical Perspectives of Magnetic Nanoparticles as Versatile Carriers
Bilal, M., Mehmood, S., Rasheed, T., & Iqbal, H. M. N. (2019) · Magnetochemistry · doi:10.3390/magnetochemistry5030042 · Cited by 69
Synthesis of aqueous ferrofluids of ZnxFe3−xO4 nanoparticles by citric acid assisted hydrothermal-reduction route for magnetic hyperthermia applications
Behdadfar, B., Kermanpur, A., Sadeghi‐Aliabadi, H., Morales, M. P., & Mozaffari, M. (2012) · Journal of Magnetism and Magnetic Materials · doi:10.1016/j.jmmm.2012.02.034 · Cited by 68
Multilayer nanoparticles with a magnetite core and a polycation inner shell as pH-responsive carriers for drug delivery
Guo, M., Yu, Y., Liu, X., Yan, H., Liu, K., Zhang, H., & Cao, Y. (2009) · Nanoscale · doi:10.1039/b9nr00244h · Cited by 68
Lectin-Conjugated Fe2O3@Au Core@Shell Nanoparticles as Dual Mode Contrast Agents forin VivoDetection of Tumor
He, X., Liu, F., Liu, L., Duan, T., Zhang, H., & Wang, Z. (2014) · Molecular Pharmaceutics · doi:10.1021/mp400456j · Cited by 68
Functionalization of magnetic nanoparticles for biomedical applications
Nguyen, D. T., & Kim, K. (2014) · Korean Journal of Chemical Engineering · doi:10.1007/s11814-014-0156-6 · Cited by 68
Grafting of P(OEGA) Onto Magnetic Nanoparticles Using Cu(0) Mediated Polymerization: Comparing Grafting “from” and “to” Approaches in the Search for the Optimal Material Design of Nanoparticle MRI Contrast Agents
Basuki, J. S., Esser, L., Zetterlund, P. B., Whittaker, M. R., Boyer, C. A., & Davis, T. P. (2013) · Macromolecules · doi:10.1021/ma401250f · Cited by 69
Magnetic Iron Oxide Nanoparticle Seeded Growth of Nucleotide Coordinated Polymers
Liang, H., Liu, B., Yuan, Q., & Liu, J. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b04038 · Cited by 68
Magnetically active Fe3O4 nanorods loaded with tissue plasminogen activator for enhanced thrombolysis
Hu, J., Huang, W., Huang, S., Zhuge, Q., Jin, K., & Zhao, Y. (2016) · Nano Research · doi:10.1007/s12274-016-1152-4 · Cited by 69
Nanopharmaceuticals: A focus on their clinical translatability
Bisso, S., & Leroux, J. (2020) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2020.119098 · Cited by 73
Potential toxicity of engineered nanoparticles in mammalian germ cells and developing embryos: treatment strategies and anticipated applications of nanoparticles in gene delivery
Das, J., Choi, Y., Song, H., & Kim, J. (2016) · Human Reproduction Update · doi:10.1093/humupd/dmw020 · Cited by 66
Green magnetic nanoparticles: a comprehensive review of recent progress in biomedical and environmental applications
Verma, C., Verma, D. K., Berdimurodov, E. T., Barsoum, I., Alfantazi, A. M., & Hussain, C. M. (2023) · Journal of Materials Science · doi:10.1007/s10853-023-08914-5 · Cited by 66
Synthesis of high intrinsic loss power aqueous ferrofluids of iron oxide nanoparticles by citric acid-assisted hydrothermal-reduction route
Behdadfar, B., Kermanpur, A., Sadeghi‐Aliabadi, H., Morales, M. P., & Mozaffari, M. (2011) · Journal of Solid State Chemistry · doi:10.1016/j.jssc.2011.12.011 · Cited by 66
Structural and magnetic characteristics of carboxymethyl dextran coated magnetic nanoparticles: From characterization to immobilization application
Vasić, K., Knez, Ž., Александровна, К. Е., Kokorin, A. I., Gyergyek, S., & Leitgeb, M. (2020) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2020.104481 · Cited by 66
Studies of nanoparticle delivery with in vitro bio-engineered microtissues
Sun, M., Lee, J., Chen, Y., & Hoshino, K. (2020) · Bioactive Materials · doi:10.1016/j.bioactmat.2020.06.016 · Cited by 67
Synthesis of Fe3O4@poly(methylmethacrylate-co-divinylbenzene) magnetic porous microspheres and their application in the separation of phenol from aqueous solutions
Tai, Y., Wang, L., Gao, J., Amer, W. A., Ding, W., & Yu, H. (2011) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2011.04.096 · Cited by 65
Polysaccharide Nanosystems for Future Progress in Cardiovascular Pathologies
Silva, A., Letourneur, D., & Chauvierre, C. (2014) · Theranostics · doi:10.7150/thno.7688 · Cited by 67
Magnetoliposomes with high USPIO entrapping efficiency, stability and magnetic properties
Σκούρας, Α., Mourtas, S., Markoutsa, E., Goltstein, M.-C. D., Wallon, C., Catoen, S., & Antimisiaris, S. G. (2011) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2011.06.010 · Cited by 64
Core–Shell Structure of Monodisperse Poly(ethylene glycol)-Grafted Iron Oxide Nanoparticles Studied by Small-Angle X-ray Scattering
Grünewald, T. A., Lassenberger, A., van Oostrum, P. D. J., Rennhofer, H., Zirbs, R., Capone, B., Vonderhaid, I., Amenitsch, H. W., Lichtenegger, H. C., & Reimhult, E. (2015) · Chemistry of Materials · doi:10.1021/acs.chemmater.5b01488 · Cited by 64
Chain formation and aging process in biocompatible polydisperse ferrofluids: Experimental investigation and Monte Carlo simulations
Bakuzis, A. F., Branquinho, L. C., Castro, L. L. E., Elói, M. T. A., & Miotto, R. (2013) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2012.12.003 · Cited by 63
The application of nanoparticles in gene therapy and magnetic resonance imaging
Herranz, F., Almarza, E., Rodríguez, I., Salinas, B., Rosell, Y., Desco, M., Bulte, J. W. M., & Ruı́z-Cabello, J. (2011) · Microscopy Research and Technique · doi:10.1002/jemt.20992 · Cited by 63
Multidentate Block-Copolymer-Stabilized Ultrasmall Superparamagnetic Iron Oxide Nanoparticles with Enhanced Colloidal Stability for Magnetic Resonance Imaging
Chan, N., Laprise‐Pelletier, M., Chevallier, P., Bianchi, A. D., Fortin, M., & Oh, J. K. (2014) · Biomacromolecules · doi:10.1021/bm500311k · Cited by 64
Zebrafish models for functional and toxicological screening of nanoscale drug delivery systems: promoting preclinical applications
Lee, K. Y., Jang, G. H., Byun, C. H., Jeun, M., Searson, P. C., & Lee, K. H. (2017) · Bioscience Reports · doi:10.1042/bsr20170199 · Cited by 63
Magnetic nanoparticles: reactive oxygen species generation and potential therapeutic applications
Mai, T., & Hilt, J. Z. (2017) · Journal of Nanoparticle Research · doi:10.1007/s11051-017-3943-2 · Cited by 63
Fabrication of Contrast Agents for Magnetic Resonance Imaging from Polymer-Brush-Afforded Iron Oxide Magnetic Nanoparticles Prepared by Surface-Initiated Living Radical Polymerization
Ohno, K., Mori, C., Akashi, T., Yoshida, S., Tago, Y., Tsujii, Y., & Tabata, Y. (2013) · Biomacromolecules · doi:10.1021/bm400770n · Cited by 62
“In vivo” imaging of atherosclerosis
Gallino, A., Stuber, M., Crea, F., Falk, E., Corti, R., Lekakis, J. P., Schwitter, J., Camici, P. G., Gaemperli, O., Valentino, M. D., et al. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.04.007 · Cited by 67
Hybrid iron oxide-copolymer micelles and vesicles as contrast agents for MRI: impact of the nanostructure on the relaxometric properties
Arosio, P., Thévenot, J., Orlando, T., Orsini, F., Corti, M., Mariani, M., Bordonali, L., Innocenti, C., Sangregorio, C., Oliveira, H., et al. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb00429e · Cited by 62
Magnetic Resonance Imaging (MRI) Contrast Agents for Tumor Diagnosis
Cheng, W., Ping, Y., Zhang, Y., Chuang, K., & Liu, Y. (2013) · Journal of Healthcare Engineering · doi:10.1260/2040-2295.4.1.23 · Cited by 62
Rational Design of Magnetic Nanoparticles as T1–T2 Dual-Mode MRI Contrast Agents
Geraldes, C. F. G. C. (2024) · Molecules · doi:10.3390/molecules29061352 · Cited by 66
Targeting Cancer with ‘Smart Bombs‘: Equipping Plant Virus Nanoparticles for A ‘Seek and Destroy’ Mission
Franzen, S., & Lommel, S. A. (2009) · Nanomedicine · doi:10.2217/nnm.09.23 · Cited by 61
Engineered magnetic hybrid nanoparticles with enhanced relaxivity for tumor imaging
Aryal, S., Key, J., Stigliano, C., Ananta, J. S., Zhong, M., & Decuzzi, P. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.07.003 · Cited by 60
Synthesis and characterization of p(NIPAM-AA-AAm) microgels for tuning of optical Properties of silver nanoparticles
Naeem, H., Farooqi, Z. H., Shah, L. A., & Siddiq, M. (2012) · Journal of Polymer Research · doi:10.1007/s10965-012-9950-1 · Cited by 60
PEG-b-AGE polymer coated magnetic nanoparticle probes with facile functionalization and anti-fouling properties for reducing non-specific uptake and improving biomarker targeting
Li, Y., Lin, R., Wang, L., Huang, J., Wu, H. C., Cheng, G., Zhou, Z., MacDonald, T. J., Yang, L. P. H., & Mao, H. Z. (2015) · Journal of Materials Chemistry B · doi:10.1039/c4tb01828a · Cited by 60
Gold nanoparticle-aided brachytherapy with vascular dose painting: Estimation of dose enhancement to the tumor endothelial cell nucleus
Ngwa, W. F., Makrigiorgos, G. M., & Berbeco, R. I. (2011) · Medical Physics · doi:10.1118/1.3671905 · Cited by 58
Tumor targeting using magnetic nanoparticle Hsp70 conjugate in a model of C6 glioma
Shevtsov, M. A., Yakovleva, L. Y., Nikolaev, B. P., Marchenko, Y., Добродумов, А. В., Onokhin, K., Onokhina, Y. S., Selkov, S. А., Михрина, А. Л., Guzhova, I. V., et al. (2013) · Neuro-Oncology · doi:10.1093/neuonc/not141 · Cited by 58
Molecular Imaging of Cancer with Nanoparticle-Based Theranostic Probes
Ma, Y.-Y., Jin, K., Wang, S.-B., Wang, H., Tong, X., Huang, D., & Mou, X. (2017) · Contrast Media & Molecular Imaging · doi:10.1155/2017/1026270 · Cited by 59
Magnetic Field‐Controlled Release of Paclitaxel Drug from Functionalized Magnetoelectric Nanoparticles
Guduru, R., & Khizroev, S. (2013) · Particle & Particle Systems Characterization · doi:10.1002/ppsc.201300238 · Cited by 58
Hyaluronic Acid-Modified Magnetic Iron Oxide Nanoparticles for MR Imaging of Surgically Induced Endometriosis Model in Rats
Zhang, H., Li, J., Sun, W., Hu, Y. M., Zhang, G., Shen, M., & Shi, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094718 · Cited by 60
Integrin-targeting thermally cross-linked superparamagnetic iron oxide nanoparticles for combined cancer imaging and drug delivery
Yu, M. K., Park, J., Jeong, Y. Y., Moon, W. K., & Jon, S. (2010) · Nanotechnology · doi:10.1088/0957-4484/21/41/415102 · Cited by 59
Nano-sized metabolic precursors for heterogeneous tumor-targeting strategy using bioorthogonal click chemistry in vivo
Lee, S., Jung, S., Koo, H., Na, J. H., Yoon, H. Y., Shim, M. K., Park, J., Kim, J.-H., Lee, S., Pomper, M. G., et al. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.09.025 · Cited by 58
Hierarchically Structured Magnetic Nanoconstructs with Enhanced Relaxivity and Cooperative Tumor Accumulation
Gizzatov, A., Key, J., Aryal, S., Ananta, J. S., Cervadoro, A., Palange, A. L., Fasano, M., Stigliano, C., Zhong, M., Mascolo, D. D., et al. (2014) · Advanced Functional Materials · doi:10.1002/adfm.201400653 · Cited by 57
C-Dot Generated Bioactive Organosilica Nanospheres in Theranostics: Multicolor Luminescent and Photothermal Properties Combined with Drug Delivery Capacity
Singh, R. K., Patel, K. D., Mahapatra, C., Kang, M. S., & Kim, H. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b07494 · Cited by 57
A novel nanohybrid for cancer theranostics: folate sensitized Fe 2 O 3 nanoparticles for colorectal cancer diagnosis and photodynamic therapy
Nandi, R., Mishra, S., Maji, T. K., Manna, K., Kar, P., Banerjee, S., Dutta, S., Sharma, S., Lemmens, P., Saha, K. D., et al. (2017) · Journal of Materials Chemistry B · doi:10.1039/c6tb03292c · Cited by 56
Melt-grafting for the synthesis of core–shell nanoparticles with ultra-high dispersant density
Zirbs, R., Lassenberger, A., Vonderhaid, I., Kurzhals, S., & Reimhult, E. (2015) · Nanoscale · doi:10.1039/c5nr02313k · Cited by 55
Image-Guided Nanosystems for Targeted Delivery in Cancer Therapy
Iyer, A. K., He, J., & Amiji, M. M. (2012) · Current Medicinal Chemistry · doi:10.2174/092986712800784685 · Cited by 55
Visualizing the Knowledge Domain of Nanoparticle Drug Delivery Technologies: A Scientometric Review
Lee, Y.-C., Chen, C., & Tsai, X.-T. (2016) · Applied Sciences · doi:10.3390/app6010011 · Cited by 55
Adsorption of Amino Acids, Aspartic Acid, and Lysine onto Iron-Oxide Nanoparticles
Črešnar, K. P., Peterlin, M., Cigić, I. K., Marolt, G., Kogej, K., Mertelj, A., Gyergyek, S., & Makovec, D. (2016) · The Journal of Physical Chemistry C · doi:10.1021/acs.jpcc.6b03180 · Cited by 55
Nanoparticle Drones to Target Lung Cancer with Radiosensitizers and Cannabinoids
Ngwa, W. F., Kumar, R., Moreau, M., Dabney, R., & Herman, A. (2017) · Frontiers in Oncology · doi:10.3389/fonc.2017.00208 · Cited by 55
Plasmonic Metallic Heteromeric Nanostructures
Zheng, G., Mourdikoudis, S., & Zhang, Z. (2020) · Small · doi:10.1002/smll.202002588 · Cited by 54
Heat-activated sustaining nitric oxide release from zwitterionic diazeniumdiolate loaded in thermo-sensitive liposomes
Tai, L.-A., Wang, Y.-C., & Yang, C.-S. (2010) · Nitric Oxide · doi:10.1016/j.niox.2010.04.003 · Cited by 54

Authors: MCCARTHY, J., & WEISSLEDER, R.
Affiliations: Harvard University (US)
Corresponding author: MCCARTHY, J
ORCID: MCCARTHY, J
WEISSLEDER, R
Venue: Advanced Drug Delivery Reviews
Publisher: Elsevier BV
Published: 2008-08-17
Volume: 60
Issue: 11
Pages: 1241-1251
ISSN: 0169-409X (ISSN-L)
DOI: 10.1016/j.addr.2008.03.014
PMC: PMC2583936
OpenAlex: W2154964751
Cited by: 892
References: 92
Citations by year: 2026: 14 · 2025: 13 · 2024: 22 · 2023: 20 · 2022: 24 · 2021: 33 · 2020: 40 · 2019: 45 · 2018: 57 · 2017: 56 · 2016: 57 · 2015: 55 · 2014: 71 · 2013: 88 · 2012: 83
FWCI: 46.90
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Advanced Drug Delivery Reviews (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
Funders: National Institutes of Health (5u54ca119349-05)
National Heart, Lung, and Blood Institute (U01HL080731)
National Cancer Institute (U54CA126515, U54 CA-119349)
Topics: Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
Keywords: magnetic nanoparticles, targeted imaging, theranostics, MRI contrast agents, affinity ligands, phage display, aptamers, immunoglobulins, tumor imaging, atherosclerosis, diabetes mellitus, multifunctional nanomaterials
MeSH terms: Animals, Biocompatible Materials, Diagnostic Imaging, Ferric Compounds, Humans, Magnetics, Neoplasms, Drug Delivery Systems, Atherosclerosis, Nanoparticles

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Multifunctional magnetic nanoparticles for targeted imaging and therapy

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks