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Cited by 555Animal Nutrition and PhysiologyRuminant Nutrition and Digestive PhysiologyVeterinary medicine and infectious diseases

The DOI matches its Crossref record; 187 of the 189 references it cites were found in a registry or an index.

Potential and challenges of tannins as an alternative to in-feed antibiotics for farm animal production

Open access
Huang, Qianqian, Liu, Xiuli, Zhao, Guoqi, Hu, Tianming, Wang, Yuxi·2018·Animal nutrition
DOI 10.1016/j.aninu.2017.09.004PMC PMC6104569
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Abstract

Naturally occurring plant compounds including tannins, saponins and essential oils are extensively assessed as natural alternatives to in-feed antibiotics. Tannins are a group of polyphenolic compounds that are widely present in plant region and possess various biological activities including antimicrobial, anti-parasitic, anti-viral, antioxidant, anti-inflammatory, immunomodulation, etc. Therefore, tannins are the major research subject in developing natural alternative to in-feed antibiotics. Strong protein affinity is the well-recognized property of plant tannins, which has successfully been applied to ruminant nutrition to decrease protein degradation in the rumen, and thereby improve protein utilization and animal production efficiency. Incorporations of tannin-containing forage in ruminant diets to control animal pasture bloat, intestinal parasite and pathogenic bacteria load are another 3 important applications of tannins in ruminant animals. Tannins have traditionally been regarded as "anti-nutritional factor" for monogastric animals and poultry, but recent researches have revealed some of them, when applied in appropriate manner, improved intestinal microbial ecosystem, enhanced gut health and hence increased productive performance. The applicability of plant tannins as an alternative to in-feed antibiotics depends on many factors that contribute to the great variability in their observed efficacies.

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Crossref · 10.1016/j.aninu.2017.09.004

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Figures

Fig. 1 Model structures of (A) hydrolyzable tannins, (B) condensed tannins and (C) phlorotannins.
Fig. 1 Model structures of (A) hydrolyzable tannins, (B) condensed tannins and (C) phlorotannins.CC BY-NC-ND · PubMed Central
Fig. 2 Aggregation of Escherichia coli (strain 25922) cell incubated for 10 h with (A) 0 (Control) or (B) 200 μg/mL of condensed tannins of purple prairie clover (Dalea purpurea Vent.), and transmission electron micrographs of E. coli O157:H7 strain 3081 incubated for 24 h with (C) 0 or 50 μg/mL of (D) phlorotannins, (E) hydrolyzable tannins or (F) condensed tannins. Adapted from Wang et al., 2009, Wang et al., 2013 and Liu et al. (2013).
Fig. 2 Aggregation of Escherichia coli (strain 25922) cell incubated for 10 h with (A) 0 (Control) or (B) 200 μg/mL of condensed tannins of purple prairie clover (Dalea purpurea Vent.), and transmission electron micrographs of E. coli O157:H7 strain 3081 incubated for 24 h with (C) 0 or 50 μg/mL of (D) phlorotannins, (E) hydrolyzable tannins or (F) condensed tannins. Adapted from Wang et al., 2009, Wang et al., 2013 and Liu et al. (2013).CC BY-NC-ND · PubMed Central
Fig. 3 Regression of bloat rate and proportion of sainfoin in herbage mass determined for beef steers (n = 12) grazing forage re-growth in 1999 and 2000 (adapted from Wang et al. (2006)).
Fig. 3 Regression of bloat rate and proportion of sainfoin in herbage mass determined for beef steers (n = 12) grazing forage re-growth in 1999 and 2000 (adapted from Wang et al. (2006)).CC BY-NC-ND · PubMed Central

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Citations

Cites

Research works printed but not linked: 8

  1. Barham, 2001, Effects of Tascor14 on prevalence levels of enterohemorragic Escherichia coli and Salmonella spp. in feedlot steers, J Anim Sci, 79, 257
  2. Behrends, 2000, Tasco supplementation in feedlot cattle: effects on pathogen loads, J Anim Sci, 78, 106
  3. Brus, 2013, Effect of chestnut (Castanea sativa Mill.) wood tannins and organic acids on growth performance and faecal microbiota of pigs from 23 to 127 days of age, Bulg J Agric Sci, 19, 841
  4. Chen, 1997, A hypothesis on phaeophyceae polyphenols, their structural unit and mechanism of the formation (in Chinese with English summary), Oceanol Limnol Sin, 28, 225
  5. Dutta, 2012, Effect of supplementing tanniferous tree leaves mixture on immune response and GI nematodes in kids, Livest Res Rural Dev, 24
  6. Mcleod, 1974, Plant tannins-Their role in forage quality, Nutr Abstr Rev, 44, 803
  7. Van Soest, 1982, vol. 44, 2552
  8. Wang, 2011, Brown algae as feed additive: nutritional and health impacts on ruminant animals – a review, 1

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Metadata

Authors
Huang, Q., Liu, X., Zhao, G., Hu, T., & Wang, Y.
Affiliations
  • Yangzhou University (CN)
  • Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences (CN)
  • Northwest A&F University (CN)
  • Agriculture and Agri-Food Canada (CA)
Corresponding author
Wang, Yuxi
ORCID
Venue
Animal nutrition
Publisher
Elsevier BV
Published
2018-06
Volume
4
Issue
2
Pages
137-150
ISSN
  • 2405-6383 (ISSN-L)
  • 2405-6545
DOI
10.1016/j.aninu.2017.09.004
PMC
PMC6104569
OpenAlex
W2761389834
Cited by
555
References
189
Citations by year
2026: 58 · 2025: 68 · 2024: 94 · 2023: 70 · 2022: 83 · 2021: 86 · 2020: 61 · 2019: 25 · 2018: 9
FWCI
3.15
Type
journal article
Language
en
Open access
Licence
Locations
  • Animal nutrition (publishedVersion, cc-by-nc-nd)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Natural Science Foundation of Jiangsu Province (BK20170494)
  • Agriculture Research System of China (CARS-36)
  • Agriculture and Agri-Food Canada
  • China Postdoctoral Science Foundation (2017M611930)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Ruminant Nutrition and Digestive Physiology
  • Health Sciences › Veterinary › Small Animals › Veterinary medicine and infectious diseases
Keywords
tannins, in-feed antibiotics, natural antibiotic alternatives, polyphenols, ruminant nutrition, protein degradation, intestinal parasites, poultry gut health, antinutritional factors, antimicrobial activity, saponins, essential oils, livestock productivity

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