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Targeted and effective photodynamic therapy for cancer using functionalized nanomaterials
Open accessAbstract
Photodynamic therapy (PDT) is an emerging, non-invasive therapeutic strategy that involves photosensitizer (PS) drugs and external light for the treatment of diseases. Despite the great progress in PS-mediated PDT, their clinical applications are still hampered by poor water solubility and tissue/cell specificity of conventional PS drugs. Therefore, great efforts have been made towards the development of nanomaterials that can tackle fundamental challenges in conventional PS drug-mediated PDT for cancer treatment. This review highlights recent advances in the development of nano-platforms, in which various functionalized organic and inorganic nanomaterials are integrated with PS drugs, for significantly enhanced efficacy and tumor-selectivity of PDT.
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Metadata
- Authors
- Hong, E. J., Choi, D. G., & Shim, M. S.
- Venue
- Acta Pharmaceutica Sinica B
- Publisher
- Elsevier BV
- Published
- 2016-07
- Volume
- 6
- Issue
- 4
- Pages
- 297-307
- ISSN
- 2211-3835 (ISSN-L)
- OpenAlex
- W2337485356
- Cited by
- 361
- References
- 69
- FWCI
- 26.48
- Type
- journal article
- Language
- en
- Open access
- gold
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