The DOI matches its Crossref record; 177 of the 177 references it cites were found in a registry or an index.
The biology, function, and applications of exosomes in cancer
Open accessAbstract
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon fusion of multivesicular bodies with the cell surface. They can transport nucleic acids, proteins, and lipids for intercellular communication and activate signaling pathways in target cells. In cancers, exosomes may participate in growth and metastasis of tumors by regulating the immune response, blocking the epithelial-mesenchymal transition, and promoting angiogenesis. They are also involved in the development of resistance to chemotherapeutic drugs. Exosomes in liquid biopsies can be used as non-invasive biomarkers for early detection and diagnosis of cancers. Because of their amphipathic structure, exosomes are natural drug delivery vehicles for cancer therapy.
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Cites
2 retracted
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The biology , function , and biomedical applications of exosomes
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Shedding light on the cell biology of extracellular vesicles
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Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
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Cited by
Lin, Z., Wu, Y., Xu, Y., Li, G., Li, Z., & Liu, T. (2022) · Molecular Cancer · doi:10.1186/s12943-022-01650-5 · Cited by 297
Biogenesis, Isolation, and Detection of Exosomes and Their Potential in Therapeutics and Diagnostics
Sonbhadra, S., Mehak, & Pandey, L. M. (2023) · Biosensors · doi:10.3390/bios13080802 · Cited by 97
Gu, Y., Du, Y., Jiang, L., Tang, X., Li, A., Zhao, Y., Lang, Y., Liu, X., & Liu, J. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01597-1 · Cited by 67
Self-citationLiu, Y., Tang, Y., Jiang, H., Zhang, X., Chen, X., Guo, J., Jin, C., & Wu, M. (2023) · Biomolecules · doi:10.3390/biom14010041 · Cited by 19
Laish, I., Levi, Z., Mahajna, H., Albshesh, A., Horesh, N., Katz, E., Feldman, D., Shinar, N., Picard, O., Yavzori, M., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.962473 · Cited by 6
Metadata
- Authors
- Liu, J., Ren, L., Li, S., Li, W., Zheng, X., Yang, Y., Fu, W., Yi, J., Wang, J., & Du, G.
- Venue
- Acta Pharmaceutica Sinica B
- Publisher
- Elsevier BV
- Published
- 2021-09
- Volume
- 11
- Issue
- 9
- Pages
- 2783-2797
- ISSN
- 2211-3835 (ISSN-L)
- OpenAlex
- W3120884777
- Cited by
- 561
- References
- 177
- FWCI
- 22.81
- Type
- journal article
- Language
- en
- Open access
- gold
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- Liu, J., Ren, L., Li, S., Li, W., Zheng, X., Yang, Y., Fu, W., Yi, J., Wang, J., & Du, G. (2021). The biology, function, and applications of exosomes in cancer. Acta Pharmaceutica Sinica B. https://doi.org/10.1016/j.apsb.2021.01.001
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
