The road ahead for health and lifespan interventions

The Hallmarks of Aging

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mTOR Signaling in Growth, Metabolism, and Disease

Saxton, R. A., & Sabatini, D. M. (2017) · Cell · doi:10.1016/j.cell.2017.02.004 · Cited by 7,555

DNA methylation age of human tissues and cell types

Horvath, S. (2013) · Genome Biology · doi:10.1186/gb-2013-14-10-r115 · Cited by 7,075

Resveratrol improves health and survival of mice on a high-calorie diet

Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature · doi:10.1038/nature05354 · Cited by 4,290

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

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Extending Healthy Life Span—From Yeast to Humans

Fontana, L., Partridge, L., & Longo, V. D. (2010) · Science · doi:10.1126/science.1172539 · Cited by 3,023

The World Report on Ageing and Health

Beard, J., Officer, A. M., & Cassels, A. (2016) · The Gerontologist · doi:10.1093/geront/gnw037 · Cited by 2,911

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

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Senolytics improve physical function and increase lifespan in old age

Xu, M., Pirtskhalava, T., Farr, J. N., Weigand, B. M., Palmer, A. K., Weivoda, M. M., Inman, C. L., Ogrodnik, M. B., Hachfeld, C. M., Fraser, D. G., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0092-9 · Cited by 2,287

Mitochondrial and metabolic dysfunction in ageing and age-related diseases

Amorim, J. A., Coppotelli, G., Rolo, A. P., Palmeira, C. M., Ross, J. M., & Sinclair, D. A. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00626-7 · Cited by 990

Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice

Acosta-Rodríguez, V., Rijo-Ferreira, F., Izumo, M., Xu, P., Wight-Carter, M., Green, C. B., & Takahashi, J. S. (2022) · Science · doi:10.1126/science.abk0297 · Cited by 390

Role of AMPK mediated pathways in autophagy and aging

Ge, Y., Zhou, M., Chen, C., Wu, X., & Wang, X. (2021) · Biochimie · doi:10.1016/j.biochi.2021.11.008 · Cited by 262

Targeting immune dysfunction in aging

Borgoni, S., Kudryashova, K. S., Burka, K., & de Magalhães, J. P. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101410 · Cited by 230

Association of Pace of Aging Measured by Blood-Based DNA Methylation With Age-Related Cognitive Impairment and Dementia

Sugden, K., Caspi, A., Elliott, M. L., Bourassa, K. J., Chamarti, K., Corcoran, D. L., Hariri, A. R., Houts, R. M., Kothari, M., Kritchevsky, S., et al. (2022) · Neurology · doi:10.1212/wnl.0000000000200898 · Cited by 156

Asynchronous, contagious and digital aging

Rando, T. A., & Wyss-Coray, T. (2021) · Nature Aging · doi:10.1038/s43587-020-00015-1 · Cited by 121

Longitudinal phenotypic aging metrics in the Baltimore Longitudinal Study of Aging

Kuo, P., Schrack, J. A., Levine, M. E., Shardell, M. D., Simonsick, E. M., Chia, C. W., Moore, A. Z., Tanaka, T., An, Y., Karikkineth, A. C., et al. (2022) · Nature Aging · doi:10.1038/s43587-022-00243-7 · Cited by 97

Cancer-related accelerated ageing and biobehavioural modifiers: a framework for research and clinical care

Carroll, J., Bower, J. E., & Ganz, P. A. (2021) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-021-00580-3 · Cited by 79

Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience

Moskalev, A., Stambler, I., & Caruso, C. (2020) · Aging and Disease · doi:10.14336/ad.2020.0603 · Cited by 73

Pentadecanoic Acid (C15:0), an Essential Fatty Acid, Shares Clinically Relevant Cell-Based Activities with Leading Longevity-Enhancing Compounds

Venn-Watson, S. K., & Schork, N. J. (2023) · Nutrients · doi:10.3390/nu15214607 · Cited by 84

Nutrients and Pathways that Regulate Health Span and Life Span

Pignatti, C., D’Adamo, S., Stefanelli, C., Flamigni, F., & Cetrullo, S. (2020) · Geriatrics · doi:10.3390/geriatrics5040095 · Cited by 68

Study of Longitudinal Aging in Mice: Presentation of Experimental Techniques

Palliyaguru, D. L., Teixeira, C. V. L., Duregon, E., Germanio, C. D., Alfaras, I., Mitchell, S. J., Navas‐Enamorado, I., Shiroma, E. J., Studenski, S. A., Bernier, M., et al. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa285 · Cited by 62

The flavonoid corylin exhibits lifespan extension properties in mouse

Wang, T., Tseng, W.-C., Leu, Y., Chen, C., Chi, Y.-C., Chi, Y.-C., Cheng, S.-F., Lai, C.-Y., Kuo, C.-H., Yang, S., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28908-2 · Cited by 61

Disability and the risk of subsequent mortality in elderly: a 12-year longitudinal population-based study

Yang, Y., Du, Z., Liu, Y., Lao, J., Sun, X., & Tang, F. (2021) · BMC Geriatrics · doi:10.1186/s12877-021-02611-1 · Cited by 56

Cardiovascular disease and the biology of aging

Moturi, S., Ghosh-Choudhary, S. K., & Finkel, T. (2022) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2022.04.005 · Cited by 56

Unlocking longevity: the role of telomeres and its targeting interventions

Schellnegger, M., Hofmann, E., Carnieletto, M., & Kamolz, L. (2024) · Frontiers in Aging · doi:10.3389/fragi.2024.1339317 · Cited by 65

Neuroprotective effects of Canagliflozin: Lessons from aged genetically diverse UM‐HET3 mice

Jayarathne, H. S. M., Debarba, L. K., Jaboro, J. J., Ginsburg, B. C., Miller, R. A., & Sadagurski, M. (2022) · Aging Cell · doi:10.1111/acel.13653 · Cited by 45

Potential Active Marine Peptides as Anti-Aging Drugs or Drug Candidates

Yang, H., Zhang, Q., Zhang, B., Zhao, Y., & Wang, N. (2023) · Marine Drugs · doi:10.3390/md21030144 · Cited by 44

Frailty and HIV: Moving from Characterization to Intervention

Erlandson, K. M., & Piggott, D. A. (2021) · Current HIV/AIDS Reports · doi:10.1007/s11904-021-00554-1 · Cited by 44

Decoding and rejuvenating human ageing genomes: Lessons from mosaic chromosomal alterations

Dai, X., & Guo, X. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101342 · Cited by 39

Organoids: An Emerging Tool to Study Aging Signature across Human Tissues. Modeling Aging with Patient-Derived Organoids

Torrens‐Mas, M., Perelló-Reus, C. M., Navas-Enamorado, C., Ibargüen-González, L., Sánchez-Polo, A., Segura‐Sampedro, J. J., Masmiquel, L., Barceló, C., & González‐Freire, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910547 · Cited by 38

Fecal microbiota transplantation, a tool to transfer healthy longevity

Novelle, M. G., Naranjo-Martínez, B., Lopez-Canovas, J. L., & Díaz‐Ruiz, A. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102585 · Cited by 35

Mitochondrial sirtuins, key regulators of aging

Ji, Z., Liu, G., & Qu, J. T. (2025) · Life Medicine · doi:10.1093/lifemedi/lnaf019 · Cited by 32

Static Stretching Reduces Motoneuron Excitability: The Potential Role of Neuromodulation

Trajano, G. S., & Blazevich, A. J. (2021) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000243 · Cited by 35

Resveratrol elongates the lifespan and improves antioxidant activity in the silkworm Bombyx mori

Song, J., Liu, L., Hao, K., Mao, S., Tang, Y., Tong, X., & Dai, F. (2020) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2020.06.005 · Cited by 29

Phenotypic Screening in C. elegans as a Tool for the Discovery of New Geroprotective Drugs

Bulterijs, S., & Braeckman, B. P. (2020) · Pharmaceuticals · doi:10.3390/ph13080164 · Cited by 31

Unveiling the Longevity Potential of Natural Phytochemicals: A Comprehensive Review of Active Ingredients in Dietary Plants and Herbs

Wang, Y., Cao, X., Ma, J., Liu, S., Jin, X., & Liu, B. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c07756 · Cited by 31

Gentiopicroside, a Secoiridoid Glycoside from Gentiana rigescens Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress

Liu, Q., Cheng, L., Matsuura, A., Xiang, L., & Qi, J. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/9125752 · Cited by 26

Anti-aging effects of polysaccharides from quinoa (Chenopodium quinoa Willd.) in improving memory and cognitive function

Hu, Y., Zhou, J., Cao, Y., Zhang, J., & Zou, L. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105097 · Cited by 27

Xanthohumol prolongs lifespan and decreases stress-induced mortality in Drosophila melanogaster

Wongchum, N., & Dechakhamphu, A. (2021) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2021.108994 · Cited by 24

Does Diet Have a Role in the Treatment of Alzheimer's Disease?

Thelen, M., & Brown‐Borg, H. M. (2020) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2020.617071 · Cited by 24

Novel Strategies for Healthy Brain Aging

Wahl, D., Cavalier, A. N., & LaRocca, T. J. (2021) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000242 · Cited by 26

Echocardiographic heart ageing patterns predict cardiovascular and non-cardiovascular events and reflect biological age: the SardiNIA study

Ganau, A., Orrù, M., Floris, M., Saba, P. S., Loi, F., Sanna, G. D., Marongiu, M., Balaci, L., Curreli, N., Ferreli, L. A. P., et al. (2023) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwad254 · Cited by 22

The phenotype of aging in the dog: how aging impacts the health and well-being of dogs and their caregivers

McKenzie, B. A., Chen, F., & LaCroix‐Fralish, M. L. (2022) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.22.02.0088 · Cited by 20

Key Molecular Mechanisms of Aging, Biomarkers, and Potential Interventions

Proshkina, E., Solovev, I. A., Shaposhnikov, M. V., & Moskalev, A. (2020) · Molecular Biology · doi:10.1134/s0026893320060096 · Cited by 21

Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools

Hepowit, N. L., Macêdo, J. K. A., Young, L. E. A., Liu, K., Sun, R. C., MacGurn, J. A., & Dickson, R. C. (2021) · Aging · doi:10.18632/aging.202849 · Cited by 18

Compression of morbidity by interventions that steepen the survival curve

Yang, Y., Mayo, A., Levy, T., Raz, N., Shenhar, B., Jarosz, D. F., & Alon, U. (2025) · Nature Communications · doi:10.1038/s41467-025-57807-5 · Cited by 18

Ключевые молекулярные механизмы старения, биомаркеры и потенциальные интервенции

Proshkina, E., Соловьёв, И. А., Shaposhnikov, M. V., & Moskalev, A. A. (2020) · Molecular Biology · doi:10.31857/s0026898420060099 · Cited by 18

COVID-19: A Challenge to Physiology of Aging

Golubev, A. G. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.584248 · Cited by 18

The Potential of Resveratrol to Act as a Caloric Restriction Mimetic Appears to Be Limited: Insights from Studies in Mice

Pallauf, K., Günther, I., Kühn, G., Chin, D., de Pascual‐Teresa, S., & Rimbach, G. H. (2020) · Advances in Nutrition · doi:10.1093/advances/nmaa148 · Cited by 15

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Zwi‐Dantsis, L., Jayarajan, V., Church, G. M., Kamm, R. D., de Magalhães, J. P., & Moeendarbary, E. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202500217 · Cited by 16

Socially Active Aging and Self-Reported Health: Building a Sustainable Solidarity Ecosystem

Gil‐Lacruz, A. I., Gil‐Lacruz, M., & Gil, M. I. S. (2020) · Sustainability · doi:10.3390/su12072665 · Cited by 15

The future of healthy aging: translation of geroscience discoveries to public health practice

Ungvari, Z. I., & Ádány, R. (2021) · European Journal of Public Health · doi:10.1093/eurpub/ckaa212 · Cited by 15

Bridging expectations and science: a roadmap for the future of longevity interventions

Yu, D., Zeng, X., Barzilai, D. A., Thor, D., & Lyu, Y.-X. (2025) · Biogerontology · doi:10.1007/s10522-025-10278-z · Cited by 16

Mitochondrial Dysfunction in Aging: Future Therapies and Precision Medicine Approaches

Jia, L., Wei, Z., Luoqian, J., Wang, X., & Huang, C. (2025) · MedComm – Future Medicine · doi:10.1002/mef2.70026 · Cited by 14

Effects of lifespan-extending interventions on cognitive healthspan

Čulig, L., Sahbaz, B. D., & Bohr, V. A. (2022) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2022.36 · Cited by 14

Measurements of damage and repair of binary health attributes in aging mice and humans reveal that robustness and resilience decrease with age, operate over broad timescales, and are affected differently by interventions

Farrell, S., Kane, A. E., Bisset, E. S., Howlett, S. E., & Rutenberg, A. D. (2022) · eLife · doi:10.7554/elife.77632 · Cited by 16

Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop

Brinkley, T. E., Justice, J. N., Basu, S., Bauer, S. R., Loh, K. P., Mukli, P., Ng, T. K. S., Turney, I. C., Ferrucci, L., Cummings, S. R., et al. (2022) · GeroScience · doi:10.1007/s11357-022-00661-w · Cited by 13

The effects of Cyperus rotundus L. extracts on the longevity of Drosophila melanogaster

Wongchum, N., Dechakhamphu, A., Mading, A., Khamphaeng, T., Pinlaor, S., Pinmongkhonkul, S., & Tanomtong, A. (2022) · South African Journal of Botany · doi:10.1016/j.sajb.2022.04.037 · Cited by 13

The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside

Birkisdóttir, M. B., van Galen, I., Brandt, R. M. C., Barnhoorn, S., van Vliet, N., van Dijk, C., Nagarajah, B., Imholz, S., van Oostrom, C. T., Reiling, E., et al. (2022) · Frontiers in Aging · doi:10.3389/fragi.2022.1005322 · Cited by 13

Calorie restriction mimetics against aging and inflammation

Chaudhary, S., Chaudhary, M. R., Jena, M. K., Rath, P. K., Mishra, B. P., Paital, B., Vyas, A., Sahoo, D. K., Singh, P., & Mehdi, M. M. (2025) · Biogerontology · doi:10.1007/s10522-025-10269-0 · Cited by 13

Evaluation of lifespan promoting effects of biofortified wheat in Drosophila melanogaster

Pandey, M., Bansal, S., & Chawla, G. (2022) · Experimental Gerontology · doi:10.1016/j.exger.2022.111697 · Cited by 11

(Un-) healthy ageing: Geographic inequalities in disability-free life expectancy in England and Wales

Norman, P. D., Exeter, D. J., Shelton, N. J., Head, J. A., & Murray, E. T. (2022) · Health & Place · doi:10.1016/j.healthplace.2022.102820 · Cited by 12

A Framework for an Effective Healthy Longevity Clinic

Mironov, S., Borysova, O., Morgunov, I., Zhou, Z., & Moskalev, A. (2024) · Aging and Disease · doi:10.14336/ad.2024.0328-1 · Cited by 14

Using Microbiome-Based Approaches to Deprogram Chronic Disorders and Extend the Healthspan following Adverse Childhood Experiences

Dietert, R. R., & Dietert, J. M. (2022) · Microorganisms · doi:10.3390/microorganisms10020229 · Cited by 12

Harnessing the effects of endurance exercise to optimize cognitive health: Fundamental insights from Dr. Mark P. Mattson

Jachim, S. K., Sakamoto, A. E., Zhang, X., Pearsall, V. M., Schafer, M. J., & LeBrasseur, N. K. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101147 · Cited by 12

Gene expressions associated with longer lifespan and aging exhibit similarity in mammals

Takasugi, M., Yoshida, Y., Nonaka, Y., & Ohtani, N. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad544 · Cited by 10

Chlorogenic Acid and Biohanin A from Trifolium pratense L. Callus Culture Extract: Functional Activity In Vivo

Milentyeva, I., Vesnina, A. D., Fedorova, A., Остапова, Е. В., & Larichev, T. (2023) · Food Processing Techniques and Technology · doi:10.21603/2074-9414-2023-4-2475 · Cited by 9

Alternate Day Fasting Enhances Intestinal Epithelial Function During Aging by Regulating Mitochondrial Metabolism

Quan, H., Lu, Y., Lin, Y., Xue, P., Zhang, Y., Wang, Y., Yu, W., Lin, X., Yang, W., Lv, C., et al. (2025) · Aging Cell · doi:10.1111/acel.70052 · Cited by 9

The role of quality of life data as an endpoint for collecting real-world evidence within geroscience clinical trials

Harinath, G., Zalzala, S., Nyquist, A., Wouters, M. C. A., Isman, A., Moel, M., Verdin, E. M., Kaeberlein, M. R., Kennedy, B. K., & Bischof, E. Y. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102293 · Cited by 9

The past-tense debate

Pinker, S. A., & Ullman, M. T. (2002) · Cited by 8

Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review

Liebich, A., Zheng, S., Schachner, T., Mair, J. L., Jovanova, M., Müller‐Riemenschneider, F., & Kowatsch, T. (2024) · PLoS ONE · doi:10.1371/journal.pone.0301763 · Cited by 7

Targeting Aging and Longevity with Exogenous Nucleotides (TALENTs): Rationale, Design, and Baseline Characteristics from a Randomized Controlled Trial in Older Adults

Wang, S., Song, L., Fan, R., Chen, Q., You, M., Cai, M., Wu, Y., Li, Y., & Xu, M. (2024) · Nutrients · doi:10.3390/nu16091343 · Cited by 7

Multimorbidity patterns in older adults from Northern Netherlands: comparing factor analysis and latent class analysis solutions

Ogaz-González, R., Zou, Q., Du, Y., Gutiérrez‐Robledo, L. M., Escamilla-Santiago, R. A., López‐Cervantes, M., & Corpeleijn, E. (2025) · BMC Geriatrics · doi:10.1186/s12877-025-06029-x · Cited by 6

Gut Microbiota and Depression, Anxiety, and Cognitive Disorders

Hur, H. J., & Park, H. Y. (2022) · Springer eBooks · doi:10.1007/978-981-19-0120-1_23 · Cited by 6

Biology of Healthy Aging: Biological Hallmarks of Stress Resistance Related and Unrelated to Longevity in Humans

Badial, K., Lacayo, P., & Murakami, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251910493 · Cited by 8

Acarbose-Loaded PLGA Microspheres: Efficient Encapsulation and Controlled Release

Mishra, A., Waghamare, S., & Khanage, S. G. (2025) · Journal of Drug Delivery and Therapeutics · doi:10.22270/jddt.v15i6.7165 · Cited by 5

Microbiome transplants may not improve health and longevity in Drosophila melanogaster

Levine, B. H., & Hoffman, J. M. (2025) · Biology Open · doi:10.1242/bio.061745 · Cited by 5

Modern Approaches to Diagnostics and Correction of Aging Biomarkers

Ринатовна, Г. И., Kudryashova, I. S., Kostromina, E. Y., Yakovlev, M. Y., Yafarova, I. K., Гаптрауфович, Г. Р., Kaverina, I. A., Ershov, A. V., Isaev, A. N., & Moskalev, A. (2021) · Bulletin of Rehabilitation Medicine · doi:10.38025/2078-1962-2021-20-6-96-102 · Cited by 7

In Contrast to Dietary Restriction, Application of Resveratrol in Mice Does not Alter Mouse Major Urinary Protein Expression

Pallauf, K., Günther, I., Chin, D., & Rimbach, G. H. (2020) · Nutrients · doi:10.3390/nu12030815 · Cited by 5

Mikhail ‘Misha’ Blagosklonny’s enduring legacy in geroscience: the hyperfunction theory and the therapeutic potential of rapamycin

Barzilai, D. A. (2025) · Aging · doi:10.18632/aging.206189 · Cited by 4

How to train your rodent: Recommendations for the preclinical study of exercise-induced benefits in metabolic research

Raun, S. H., Pham, T. C. P., Viggars, M. R., Ato, S., Takagaki, Y., Yan, Z., Bock, K. D., Hornberger, T. A., Richter, E. A., Auwerx, J. H., et al. (2026) · Cell Metabolism · doi:10.1016/j.cmet.2026.03.005 · Cited by 5

Identifying patterns of multimorbidity, polypharmacy and frailty in the elderly: a clustering analysis of baseline data from a French, randomised, controlled trial in primary care

Guellich, A., Oubaya, N., Cogneau, J., Lacoin, F., Clerc, P., Audureau, É., & Breton, J. L. (2025) · BMJ Open · doi:10.1136/bmjopen-2023-083584 · Cited by 4

Integration of immune-metabolic signals to preserve healthy aging

Goldberg, E. L. (2020) · Translational Medicine of Aging · doi:10.1016/j.tma.2020.07.005 · Cited by 4

Bridging geriatric medicine, clinical pharmacology and ageing biology to understand and improve outcomes of medicines in old age and frailty

Hilmer, S. N. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101457 · Cited by 4

Personalized medicine: will it work for decreasing age-related morbidities?

Martens, C. R., Wahl, D., & LaRocca, T. J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-823761-8.00013-6 · Cited by 4

Mikronährstoffe, Immunüberwachung und Immunseneszenz

Stoll, G. (2020) · Deutsche Zeitschrift für Onkologie · doi:10.1055/a-1240-8399 · Cited by 4

Living healthily to 120: Implications for entrepreneurship

van Gelderen, M. (2025) · Journal of Business Venturing · doi:10.1016/j.jbusvent.2025.106512 · Cited by 4

Male rat leukocyte population dynamics predict a window for intervention in aging

Yanai, H., Dunn, C., Park, B., Coletta, C. E., McDevitt, R. A., McNeely, T. L., Leone, M., Wersto, R. P., Perdue, K. A., & Beerman, I. (2022) · eLife · doi:10.7554/elife.76808 · Cited by 3

BayesAge 2.0: a maximum likelihood algorithm to predict transcriptomic age

Mboning, L., Costa, E. K., Chen, J., Bouchard, L., & Pellegrini, M. A. (2025) · GeroScience · doi:10.1007/s11357-024-01499-0 · Cited by 3

Dynamics of genetic and somatic trade-offs in ageing and mortality

Arends, D., Ashbrook, D. G., Roy, S., Lu, L., Sloan, Z., Centeno, A. G., Lamour, K. H., de Magalhães, J. P., Prins, P., Broman, K. W., et al. (2026) · Nature · doi:10.1038/s41586-026-10407-9 · Cited by 3

Reduced sphingolipid biosynthesis modulates proteostasis networks to enhance longevity

Hepowit, N. L., Blalock, E. M., Lee, S., Bretland, K. M., MacGurn, J. A., & Dickson, R. C. (2023) · Aging · doi:10.18632/aging.204485 · Cited by 4

The inner fire: the shifting paradigm of complement system in aging

Triggianese, P., & Della-Morte, D. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1795833 · Cited by 3

Association of proBNPage with all-cause and cardiovascular mortality among US adults: an analysis of data from the National Health and Nutrition Examination Survey

Zhou, Z., Jiang, H., Ren, J. L., Li, Y., Su, C., Zhang, X., Shao, Y., Xia, W., Wang, Y., Wu, F., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-093052 · Cited by 2

Blueberries for brainpower: A systematic review and meta-analysis with Bayesian post hoc analysis of RCTS exploring cognitive function in the elderly with prior cognitive decline

da Silva, A. B. N., de Oliveira, G. M., Ruelas, M. G., Gadelha, M., Santos, A. C. F. D. F., & Zamora, F. V. (2025) · Biogerontology · doi:10.1007/s10522-025-10308-w · Cited by 3

A Glance Back at the Journal of Gerontology—Coffee, Dietary Interventions and Life Span

Duregon, E., Bernier, M., & de Cabo, R. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa075 · Cited by 2

Targeting Mitochondria and Redox Dyshomeostasis in Brain Ageing: An Update

Cardoso, S., & Moreira, P. I. (2021) · Healthy ageing and longevity · doi:10.1007/978-3-030-84965-8_8 · Cited by 2

Literatur Review: Pembatasan energi untuk peningkatan umur panjang. Manajemen alternatif terhadap metabolik obesitas

Rose, S., Noer, E. R., Muniroh, M., & Kartini, A. (2023) · AcTion Aceh Nutrition Journal · doi:10.30867/action.v8i1.602 · Cited by 3

Aging-Related Multisystem Dysregulation Over the Adult Life Span and Physical Function in Later Life: The Atherosclerosis Risk in Communities (ARIC) Study

Lü, Y., Pike, J. R., Kucharska‐Newton, A., Palta, P., Whitsel, E. A., Bey, G., Zannas, A. S., Windham, B. G., Walker, K. A., Griswold, M. E., et al. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac236 · Cited by 2

Vitamins, minerals, and antiaging drugs in older adults

Cankurtaran, M., & Ceylan, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-98804-9.00010-4 · Cited by 2

Dysregulated proteostasis

Al-Mufti, Y., Cranwell, S., & Samant, R. S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91617-2.00004-3 · Cited by 1

Beta-Hydroxybutyrate but not NMN supplementation mimics caloric restriction reducing early mortality in Daphnia

Pearson, A. C., & Yampolsky, L. Y. (2025) · Biogerontology · doi:10.1007/s10522-025-10313-z · Cited by 1

Integrative Omics Reveal Female‐Specific Benefits of p16 + Cell Clearance in Aging Mice

Lin, Y., Wang, B., Huang, M., Wolters, J. C., & Demaria, M. (2025) · Advanced Science · doi:10.1002/advs.202509444 · Cited by 1

Spontaneous chordoma: a case report on a female UM-HET3 mouse from the SLAM study

Duregon, E., Teixeira, C. V. L., & de Cabo, R. (2020) · Aging Pathobiology and Therapeutics · doi:10.31491/apt.2020.12.043 · Cited by 1

Performance of Older Adult Regarding Their Health Maintenance Measures

Mohamed, S. O., Ahmed, H. I., & Ellatef, M. A. B. A. (2022) · Egyptian Journal of Health Care · doi:10.21608/ejhc.2022.261325 · Cited by 1

The associations between the energy and timing of sugar-sweetened beverage intake and phenotypic age acceleration in U.S. adults: a cross-sectional survey of NHANES 2007–2010

Xia, T., Qian, Y., Zhang, Y., & Shan, G. (2025) · BMC Public Health · doi:10.1186/s12889-024-21249-3 · Cited by 3

Endokrinológiai tényezők és metabolikus folyamatok szerepe az élettartam szabályozásában

Halmos, T., & Suba, I. (2021) · Orvosi Hetilap · doi:10.1556/650.2021.32200 · Cited by 1

Geriatric Gastroenterology: A Geriatrician’s Perspective

Dharmarajan, T. S. (2021) · Springer eBooks · doi:10.1007/978-3-030-30192-7_1 · Cited by 1

Game changer: Navigating between challenges and hopes in geropharmacology

Chen, Q., Hartman, R., Dankiv, L., Yan, E., Young, L. H., & Barsotti, R. (2025) · Advances in pharmacology · doi:10.1016/bs.apha.2025.02.007 · Cited by 2

Aging interventions get human

Kennedy, B. K., & Pennypacker, J. K. (2015) · Oncotarget · doi:10.18632/oncotarget.3173 · Cited by 14

Translating the Science of Aging into Therapeutic Interventions

Kirkland, J. L. (2016) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a025908 · Cited by 78

The Way Forward: Translation

Kirkland, J. L., & Tchkonia, T. (2015) · Springer eBooks · doi:10.1007/978-3-319-23246-1_19

Clinical translation of interventions that target ageing: towards a longevity dividend

Palmer, A. K., & Kirkland, J. L. (2017) · Oxford University Press eBooks · doi:10.1093/med/9780198701590.003.0168