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Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop

Brinkley, Tina E., Justice, Jamie N., Basu, Shubhashrita, Bauer, Scott R., Loh, Kah Poh, Mukli, Peter, Ng, Ted Kheng Siang, Turney, Indira C., Ferrucci, Luigi, Cummings, Steven R., Kritchevsky, Stephen B.·2022·GeroScience
DOI 10.1007/s11357-022-00661-wPMC PMC9768050
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Abstract

Biologic aging reflects the genetic, molecular, and cellular changes underlying the development of morbidity and mortality with advancing chronological age. As several potential mechanisms have been identified, there is a growing interest in developing robust measures of biologic age that can better reflect the underlying biology of aging and predict age-related outcomes. To support this endeavor, the Research Centers Collaborative Network (RCCN) conducted a workshop in January 2022 to discuss emerging concepts in the field and identify opportunities to move the science forward. This paper presents workshop proceedings and summarizes the identified research needs, priorities, and recommendations for measuring biologic age. The highest priorities identified were the need for more robust measures, longitudinal studies, multidisciplinary collaborations, and translational approaches.

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Metadata

Authors
Brinkley, T. E., Justice, J. N., Basu, S., Bauer, S. R., Loh, K. P., Mukli, P., Ng, T. K. S., Turney, I. C., Ferrucci, L., Cummings, S. R., & Kritchevsky, S. B.
ORCID
Brinkley, Tina E.
Venue
GeroScience
Publisher
Springer Science and Business Media LLC
Published
2022-10-15
Volume
44
Issue
6
Pages
2573-2583
ISSN
  • 2509-2715
  • 2509-2723
DOI
10.1007/s11357-022-00661-w
PMC
PMC9768050
Cited by
13
References
20
Language
en
Licence
Funders
  • American Federation for Aging Research
  • National Institute on Aging (U24AG058556)

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