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RETRACTED: Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway
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There is an inverse relationship between BACE1 and leptin signaling: BACE1 expression is suppressed by leptin signaling, whereas BACE1 levels are increased by both obesity and T2D.
“There is evidence of an inverse relationship between BACE1 and leptin signaling. BACE1 expression is suppressed by leptin signaling, whereas BACE1 levels are increased by both obesity and T2D.”
From BACE1: More than just a β‐secretase (2022) · cites this paper as [114]
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Metadata
- Authors
- Marwarha, G., Raza, S., Meiers, C., & Ghribi, O.
- Venue
- Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Publisher
- Elsevier BV
- Published
- 2014-09
- Volume
- 1842
- Issue
- 9
- Pages
- 1587-1595
- ISSN
- 0925-4439
- PMC
- PMC4125440
- Cited by
- 107
- References
- 12
- Language
- en
- Status
- Retracted
- Update notices
- Licence
- Funders
- National Institute of Environmental Health Sciences (R01ES014826)
- National Institutes of Health
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