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PIP kinases define PI4,5P2 signaling specificity by association with effectors

Choi, Suyong, Thapa, Narendra, Tan, Xiaojun, Hedman, Andrew C., Anderson, Richard A.·2015·Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
DOI 10.1016/j.bbalip.2015.01.009PMC PMC4380618
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  • Other PI(4,5)P2 phosphatases and kinases impact trafficking and degradation of the epidermal growth factor receptor and the transferrin receptor.

    “Notably, other PI(4,5)P2 phosphatases (e.g. Lowe oculocerebrorenal syndrome protein (OCRL), also known as INPP5F) and kinases have been reported to impact trafficking and degradation of the epidermal growth factor receptor and the transferrin receptor, which are recycled and degraded in a manner similar to LDLR11–13.”

    From Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation (2020) · cites this paper as [13]

    Section 4.1 reports that PIP kinase knockdown inhibits transferrin receptor endocytosis, and section 4.3 describes PIPKIγi5-dependent sorting of the EGF receptor toward the lysosomal pathway. The cited paper thus supports the kinase-related trafficking claim, but the passages do not establish an OCRL phosphatase role or degradation of the transferrin receptor. (LLM, conf=0.85)

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Research works printed but not linked: 209

  1. Lemmon, 2008, Membrane recognition by phospholipid-binding domains, Nat. Rev. Mol. Cell Biol., 9, 99, 10.1038/nrm2328 · DOI · Paper page
  2. Stephens, 1993, Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?, Biochim. Biophys. Acta, 1179, 27, 10.1016/0167-4889(93)90072-W · DOI
  3. Anderson, 1985, Regulation of the association of membrane skeletal protein 4.1 with glycophorin by a polyphosphoinositide, Nature, 318, 295, 10.1038/318295a0 · DOI
  4. Lassing, 1985, Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin, Nature, 314, 472, 10.1038/314472a0 · DOI
  5. Suh, 2005, Regulation of ion channels by phosphatidylinositol 4,5-bisphosphate, Curr. Opin. Neurobiol., 15, 370, 10.1016/j.conb.2005.05.005 · DOI
  6. Heo, 2006, PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane, Science, 314, 1458, 10.1126/science.1134389 · DOI
  7. Ling, 2006, Movin' on up: the role of PtdIns(4,5)P(2) in cell migration, Trends Cell Biol., 16, 276, 10.1016/j.tcb.2006.03.007 · DOI
  8. Yin, 2003, Phosphoinositide regulation of the actin cytoskeleton, Annu. Rev. Physiol., 65, 761, 10.1146/annurev.physiol.65.092101.142517 · DOI
  9. Downes, 2005, Probing phosphoinositide functions in signaling and membrane trafficking, Trends Cell Biol., 15, 259, 10.1016/j.tcb.2005.03.008 · DOI
  10. Choi, 2013, IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration, EMBO J., 32, 2617, 10.1038/emboj.2013.191 · DOI
  11. Barlow, 2012, Nuclear phosphoinositides: a signaling enigma wrapped in a compartmental conundrum, Trends Cell Biol., 20, 25, 10.1016/j.tcb.2009.09.009 · DOI
  12. Catimel, 2008, The PI(3,5)P2 and PI(4,5)P2 interactomes, J. Proteome Res., 7, 5295, 10.1021/pr800540h · DOI
  13. Dixon, 2011, A screen for novel phosphoinositide 3-kinase effector proteins, Mol. Cell. Proteomics, 10, 10.1074/mcp.M110.003178 · DOI
  14. Lewis, 2011, Identification of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins by neomycin extraction, Mol. Cell. Proteomics, 10, 10.1074/mcp.M110.003376 · DOI
  15. Good, 2011, Scaffold proteins: hubs for controlling the flow of cellular information, Science, 332, 680, 10.1126/science.1198701 · DOI
  16. Rana, 1990, Role of phosphoinositides in transmembrane signaling, Physiol. Rev., 70, 115, 10.1152/physrev.1990.70.1.115 · DOI
  17. Anderson, 1999, Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes, J. Biol. Chem., 274, 9907, 10.1074/jbc.274.15.9907 · DOI
  18. Stephens, 1991, Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils, Nature, 351, 33, 10.1038/351033a0 · DOI
  19. Insall, 2001, PIP3, PIP2, and cell movement—similar messages, different meanings?, Dev. Cell, 1, 743, 10.1016/S1534-5807(01)00086-7 · DOI
  20. Sheetz, 2006, Continuous membrane–cytoskeleton adhesion requires continuous accommodation to lipid and cytoskeleton dynamics, Annu. Rev. Biophys. Biomol. Struct., 35, 417, 10.1146/annurev.biophys.35.040405.102017 · DOI
  21. Golebiewska, 2008, Diffusion coefficient of fluorescent phosphatidylinositol 4,5-bisphosphate in the plasma membrane of cells, Mol. Biol. Cell, 19, 1663, 10.1091/mbc.E07-12-1208 · DOI · Paper page
  22. Kalwa, 2010, The MARCKS protein plays a critical role in phosphatidylinositol 4,5-bisphosphate metabolism and directed cell movement in vascular endothelial cells, J. Biol. Chem., 286, 2320, 10.1074/jbc.M110.196022 · DOI
  23. Vaaraniemi, 1999, Translocation of MARCKS and reorganization of the cytoskeleton by PMA correlates with the ion selectivity, the confluence, and transformation state of kidney epithelial cell lines, J. Cell. Physiol., 181, 83, 10.1002/(SICI)1097-4652(199910)181:1<83::AID-JCP9>3.0.CO;2-G · DOI
  24. Heck, 2007, A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family, Crit. Rev. Biochem. Mol. Biol., 42, 15, 10.1080/10409230601162752 · DOI
  25. van den Bout, 2009, PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions, J. Cell Sci., 122, 3837, 10.1242/jcs.056127 · DOI
  26. Sasaki, 2009, Mammalian phosphoinositide kinases and phosphatases, Prog. Lipid Res., 48, 307, 10.1016/j.plipres.2009.06.001 · DOI
  27. Loijens, 1996, Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family, J. Biol. Chem., 271, 32937, 10.1074/jbc.271.51.32937 · DOI
  28. Schill, 2009, Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting, Biochem. J., 422, 473, 10.1042/BJ20090638 · DOI
  29. Sun, 2013, Phosphatidylinositol 4,5-bisphosphate: targeted production and signaling, Bioessays, 35, 513, 10.1002/bies.201200171 · DOI
  30. Varnai, 1998, Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools, J. Cell Biol., 143, 501, 10.1083/jcb.143.2.501 · DOI · Paper page
  31. Watt, 2002, Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1, Biochem. J., 363, 657, 10.1042/0264-6021:3630657 · DOI
  32. Hammond, 2009, Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2), Biochem. J., 422, 23, 10.1042/BJ20090428 · DOI
  33. Rong, 2012, Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation, Nat. Cell Biol., 14, 924, 10.1038/ncb2557 · DOI · Paper page
  34. Sharma, 2008, Immunostaining evidence for PI(4,5)P2 localization at the leading edge of chemoattractant-stimulated HL-60 cells, J. Leukoc. Biol., 84, 440, 10.1189/jlb.0907636 · DOI
  35. Thapa, 2012, Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cells, Dev. Cell, 22, 116, 10.1016/j.devcel.2011.10.030 · DOI
  36. Sun, 2013, Endosomal type Igamma PIP 5-kinase controls EGF receptor lysosomal sorting, Dev. Cell, 25, 144, 10.1016/j.devcel.2013.03.010 · DOI
  37. Hammond, 2014, A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi, J. Cell Biol., 205, 113, 10.1083/jcb.201312072 · DOI · Paper page
  38. Giudici, 2004, A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma, Biochem. J., 379, 489, 10.1042/bj20031394 · DOI
  39. Xia, 2011, Phosphatidylinositol 4-phosphate 5-kinase Igamma_v6, a new splice variant found in rodents and humans, Biochem. Biophys. Res. Commun., 411, 416, 10.1016/j.bbrc.2011.06.168 · DOI
  40. Giudici, 2006, The intracellular localisation and mobility of Type Igamma phosphatidylinositol 4P 5-kinase splice variants, FEBS Lett., 580, 6933, 10.1016/j.febslet.2006.11.052 · DOI
  41. Di Paolo, 2002, Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin, Nature, 420, 85, 10.1038/nature01147 · DOI · Paper page
  42. Bairstow, 2006, Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis, J. Biol. Chem., 281, 20632, 10.1074/jbc.M601465200 · DOI
  43. Ling, 2007, Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin, J. Cell Biol., 176, 343, 10.1083/jcb.200606023 · DOI
  44. Schill, 2014, Isoform 5 of PIPKIgamma regulates the endosomal trafficking and degradation of E-cadherin, J. Cell Sci., 127, 2189, 10.1242/jcs.132423 · DOI
  45. Doughman, 2003, Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling, J. Biol. Chem., 278, 23036, 10.1074/jbc.M211397200 · DOI
  46. Chao, 2010, Type I PIPK-alpha regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation, J. Cell Biol., 190, 247, 10.1083/jcb.200911110 · DOI
  47. Mao, 2009, Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis, J. Cell Biol., 184, 281, 10.1083/jcb.200806121 · DOI
  48. Mathis, 2013, Determinants of phosphatidylinositol-4-phosphate 5-kinase type Igamma90 uropod location in T-lymphocytes and its role in uropod formation, PeerJ, 1, e131, 10.7717/peerj.131 · DOI
  49. Lokuta, 2007, Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis, Mol. Biol. Cell, 18, 5069, 10.1091/mbc.E07-05-0428 · DOI
  50. Lacalle, 2007, Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement, J. Cell Biol., 179, 1539, 10.1083/jcb.200705044 · DOI
  51. Di Paolo, 2004, Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking, Nature, 431, 415, 10.1038/nature02896 · DOI
  52. Wang, 2008, Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes, J. Clin. Invest., 118, 812
  53. Wang, 2008, Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation, Proc. Natl. Acad. Sci. U. S. A., 105, 14064, 10.1073/pnas.0804139105 · DOI
  54. Sasaki, 2005, Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I {alpha}, J. Exp. Med., 201, 859, 10.1084/jem.20041891 · DOI
  55. Kettner, 2004, WIP regulates signaling via the high affinity receptor for immunoglobulin E in mast cells, J. Exp. Med., 199, 357, 10.1084/jem.20030652 · DOI
  56. Wang, 2007, PIP5KI gamma is required for cardiovascular and neuronal development, Proc. Natl. Acad. Sci. U. S. A., 104, 11748, 10.1073/pnas.0700019104 · DOI
  57. Ridley, 2011, Life at the leading edge, Cell, 145, 1012, 10.1016/j.cell.2011.06.010 · DOI
  58. Parsons, 2010, Cell adhesion: integrating cytoskeletal dynamics and cellular tension, Nat. Rev. Mol. Cell Biol., 11, 633, 10.1038/nrm2957 · DOI
  59. Petrie, 2009, Random versus directionally persistent cell migration, Nat. Rev. Mol. Cell Biol., 10, 538, 10.1038/nrm2729 · DOI
  60. Adams, 2007, Molecular regulation of angiogenesis and lymphangiogenesis, Nat. Rev. Mol. Cell Biol., 8, 464, 10.1038/nrm2183 · DOI
  61. Noritake, 2005, IQGAP1: a key regulator of adhesion and migration, J. Cell Sci., 118, 2085, 10.1242/jcs.02379 · DOI
  62. Watanabe, 2005, Regulation of microtubules in cell migration, Trends Cell Biol., 15, 76, 10.1016/j.tcb.2004.12.006 · DOI
  63. Ridley, 2003, Cell migration: integrating signals from front to back, Science, 302, 1704, 10.1126/science.1092053 · DOI
  64. Rodriguez, 2003, Conserved microtubule–actin interactions in cell movement and morphogenesis, Nat. Cell Biol., 5, 599, 10.1038/ncb0703-599 · DOI · Paper page
  65. Hartwig, 1995, Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets, Cell, 82, 643, 10.1016/0092-8674(95)90036-5 · DOI
  66. Tolias, 2000, Type Ialpha phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly, Curr. Biol., 10, 153, 10.1016/S0960-9822(00)00315-8 · DOI
  67. Shibasaki, 1997, Massive actin polymerization induced by phosphatidylinositol-4-phosphate 5-kinase in vivo, J. Biol. Chem., 272, 7578, 10.1074/jbc.272.12.7578 · DOI
  68. Golub, 2005, PI(4,5)P2-dependent microdomain assemblies capture microtubules to promote and control leading edge motility, J. Cell Biol., 169, 151, 10.1083/jcb.200407058 · DOI
  69. Thapa, 2013, PIP2 signaling, an integrator of cell polarity and vesicle trafficking in directionally migrating cells, Cell Adhes. Migr., 6, 409, 10.4161/cam.21192 · DOI
  70. Pinon, 2014, Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing, J. Cell Biol., 205, 265, 10.1083/jcb.201308136 · DOI
  71. Kalli, 2013, Conformational changes in talin on binding to anionic phospholipid membranes facilitate signaling by integrin transmembrane helices, PLoS Comput. Biol., 9, e1003316, 10.1371/journal.pcbi.1003316 · DOI
  72. Legate, 2011, Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis, EMBO J., 30, 4539, 10.1038/emboj.2011.332 · DOI
  73. Elliott, 2010, The structure of the talin head reveals a novel extended conformation of the FERM domain, Structure, 18, 1289, 10.1016/j.str.2010.07.011 · DOI
  74. Anthis, 2009, The structure of an integrin/talin complex reveals the basis of inside-out signal transduction, EMBO J., 28, 3623, 10.1038/emboj.2009.287 · DOI
  75. Goksoy, 2008, Structural basis for the autoinhibition of talin in regulating integrin activation, Mol. Cell, 31, 124, 10.1016/j.molcel.2008.06.011 · DOI
  76. Kalli, 2010, The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study, Structure, 18, 1280, 10.1016/j.str.2010.07.012 · DOI
  77. Calderwood, 2013, Talins and kindlins: partners in integrin-mediated adhesion, Nat. Rev. Mol. Cell Biol., 14, 503, 10.1038/nrm3624 · DOI
  78. Ling, 2003, Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch, J. Cell Biol., 163, 1339, 10.1083/jcb.200310067 · DOI
  79. Saltel, 2009, New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering, J. Cell Biol., 187, 715, 10.1083/jcb.200908134 · DOI
  80. Cluzel, 2005, The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells, J. Cell Biol., 171, 383, 10.1083/jcb.200503017 · DOI
  81. Hammond, 2012, PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity, Science, 337, 727, 10.1126/science.1222483 · DOI
  82. Weernink, 2004, Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42, J. Biol. Chem., 279, 7840, 10.1074/jbc.M312737200 · DOI
  83. Halstead, 2010, Rac controls PIP5K localisation and PtdIns(4,5)P synthesis, which modulates vinculin localisation and neurite dynamics, J. Cell Sci., 123, 3535, 10.1242/jcs.062679 · DOI
  84. Yamazaki, 2002, Phosphatidylinositol 4-phosphate 5-kinase is essential for ROCK-mediated neurite remodeling, J. Biol. Chem., 277, 17226, 10.1074/jbc.M109795200 · DOI
  85. van Horck, 2002, Essential role of type I(alpha) phosphatidylinositol 4-phosphate 5-kinase in neurite remodeling, Curr. Biol., 12, 241, 10.1016/S0960-9822(01)00660-1 · DOI
  86. Hernandez-Deviez, 2004, ARNO and ARF6 regulate axonal elongation and branching through downstream activation of phosphatidylinositol 4-phosphate 5-kinase alpha, Mol. Biol. Cell, 15, 111, 10.1091/mbc.E03-06-0410 · DOI
  87. Bakolitsa, 2004, Structural basis for vinculin activation at sites of cell adhesion, Nature, 430, 583, 10.1038/nature02610 · DOI
  88. Chandrasekar, 2005, Vinculin acts as a sensor in lipid regulation of adhesion-site turnover, J. Cell Sci., 118, 1461, 10.1242/jcs.01734 · DOI
  89. Rohatgi, 2000, Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate, J. Cell Biol., 150, 1299, 10.1083/jcb.150.6.1299 · DOI
  90. Rozelle, 2000, Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3, Curr. Biol., 10, 311, 10.1016/S0960-9822(00)00384-5 · DOI
  91. White, 2009, IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis, FEBS Lett., 583, 1817, 10.1016/j.febslet.2009.05.007 · DOI
  92. Johnson, 2009, IQGAP1 regulation and roles in cancer, Cell. Signal., 21, 1471, 10.1016/j.cellsig.2009.02.023 · DOI
  93. Bensenor, 2007, IQGAP1 regulates cell motility by linking growth factor signaling to actin assembly, J. Cell Sci., 120, 658, 10.1242/jcs.03376 · DOI
  94. Le Clainche, 2007, IQGAP1 stimulates actin assembly through the N-WASP-Arp2/3 pathway, J. Biol. Chem., 282, 426, 10.1074/jbc.M607711200 · DOI
  95. Watanabe, 2004, Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration, Dev. Cell, 7, 871, 10.1016/j.devcel.2004.10.017 · DOI · Paper page
  96. Fukata, 2002, Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170, Cell, 109, 873, 10.1016/S0092-8674(02)00800-0 · DOI
  97. Sakurai-Yageta, 2008, The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA, J. Cell Biol., 181, 985, 10.1083/jcb.200709076 · DOI
  98. Brandt, 2007, Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation, J. Cell Biol., 178, 193, 10.1083/jcb.200612071 · DOI
  99. White, 2012, IQGAP1 and its binding proteins control diverse biological functions, Cell. Signal., 24, 826, 10.1016/j.cellsig.2011.12.005 · DOI
  100. Grohmanova, 2004, Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of rho-GTPase regulator, J. Biol. Chem., 279, 48495, 10.1074/jbc.M408113200 · DOI
  101. Dixon, 2012, IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold, J. Biol. Chem., 287, 22483, 10.1074/jbc.M112.352773 · DOI
  102. Brandt, 2007, Get to grips: steering local actin dynamics with IQGAPs, EMBO Rep., 8, 1019, 10.1038/sj.embor.7401089 · DOI
  103. Niggli, 2005, Regulation of protein activities by phosphoinositide phosphates, Annu. Rev. Cell Dev. Biol., 21, 57, 10.1146/annurev.cellbio.21.021704.102317 · DOI
  104. Liepina, 2003, Molecular dynamics study of a gelsolin-derived peptide binding to a lipid bilayer containing phosphatidylinositol 4,5-bisphosphate, Biopolymers, 71, 49, 10.1002/bip.10375 · DOI
  105. El Sayegh, 2007, Phosphatidylinositol-4,5 bisphosphate produced by PIP5KIgamma regulates gelsolin, actin assembly, and adhesion strength of N-cadherin junctions, Mol. Biol. Cell, 18, 3026, 10.1091/mbc.E06-12-1159 · DOI
  106. Chan, 2009, FAK, PIP5KIgamma and gelsolin cooperatively mediate force-induced expression of alpha-smooth muscle actin, J. Cell Sci., 122, 2769, 10.1242/jcs.044008 · DOI
  107. Mitra, 2005, Focal adhesion kinase: in command and control of cell motility, Nat. Rev. Mol. Cell Biol., 6, 56, 10.1038/nrm1549 · DOI
  108. Thapa, 2013, Phosphatidylinositol phosphate 5-kinase Igammai2 in association with Src controls anchorage-independent growth of tumor cells, J. Biol. Chem., 288, 34707, 10.1074/jbc.M113.512848 · DOI
  109. Levinson, 2008, Structural basis for the recognition of c-Src by its inactivator Csk, Cell, 134, 124, 10.1016/j.cell.2008.05.051 · DOI
  110. Hubbard, 1999, Src autoinhibition: let us count the ways, Nat. Struct. Biol., 6, 711, 10.1038/11468 · DOI
  111. Sigal, 1994, Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids, Proc. Natl. Acad. Sci. U. S. A., 91, 12253, 10.1073/pnas.91.25.12253 · DOI
  112. Manes, 2010, An isoform-specific PDZ-binding motif targets type I PIP5 kinase beta to the uropod and controls polarization of neutrophil-like HL60 cells, FASEB J., 24, 3381, 10.1096/fj.09-153106 · DOI
  113. Takahashi, 1997, Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein, J. Biol. Chem., 272, 23371, 10.1074/jbc.272.37.23371 · DOI
  114. Franco, 2005, Regulating cell migration: calpains make the cut, J. Cell Sci., 118, 3829, 10.1242/jcs.02562 · DOI
  115. Saido, 1992, Positive regulation of mu-calpain action by polyphosphoinositides, J. Biol. Chem., 267, 24585, 10.1016/S0021-9258(18)35804-6 · DOI
  116. McCrea, 2009, Mutations in phosphoinositide metabolizing enzymes and human disease, Physiology (Bethesda), 24, 8, 10.1152/physiol.00035.2008 · DOI
  117. Di Paolo, 2006, Phosphoinositides in cell regulation and membrane dynamics, Nature, 443, 651, 10.1038/nature05185 · DOI · Paper page
  118. Kim, 2013, Inositol lipid regulation of lipid transfer in specialized membrane domains, Trends Cell Biol., 23, 270, 10.1016/j.tcb.2013.01.009 · DOI
  119. Kim, 2011, A highly dynamic ER-derived phosphatidylinositol-synthesizing organelle supplies phosphoinositides to cellular membranes, Dev. Cell, 21, 813, 10.1016/j.devcel.2011.09.005 · DOI
  120. Owen, 2004, Adaptors for clathrin coats: structure and function, Annu. Rev. Cell Dev. Biol., 20, 153, 10.1146/annurev.cellbio.20.010403.104543 · DOI
  121. Wang, 2003, Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi, Cell, 114, 299, 10.1016/S0092-8674(03)00603-2 · DOI
  122. Mills, 2003, EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking, J. Cell Biol., 160, 213, 10.1083/jcb.200208023 · DOI
  123. Wang, 2007, PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal, Mol. Biol. Cell, 18, 2646, 10.1091/mbc.E06-10-0897 · DOI
  124. Demmel, 2008, The clathrin adaptor Gga2p is a phosphatidylinositol 4-phosphate effector at the Golgi exit, Mol. Biol. Cell, 19, 1991, 10.1091/mbc.E06-10-0937 · DOI
  125. Godi, 1999, ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex, Nat. Cell Biol., 1, 280, 10.1038/12993 · DOI
  126. Ling, 2007, Type I{gamma} phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with {micro}1B adaptin, J. Cell Biol., 176, 343, 10.1083/jcb.200606023 · DOI
  127. Tilghman, 2005, Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells, J. Cell Sci., 118, 2613, 10.1242/jcs.02380 · DOI
  128. Nakano-Kobayashi, 2007, Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis, EMBO J., 26, 1105, 10.1038/sj.emboj.7601573 · DOI
  129. Honing, 2005, Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2, Mol. Cell, 18, 519, 10.1016/j.molcel.2005.04.019 · DOI
  130. Jackson, 2010, A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex, Cell, 141, 1220, 10.1016/j.cell.2010.05.006 · DOI
  131. Itoh, 2001, Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis, Science, 291, 1047, 10.1126/science.291.5506.1047 · DOI · Paper page
  132. Itoh, 2004, Regulation of endocytosis by phosphatidylinositol 4,5-bisphosphate and ENTH proteins, Curr. Top. Microbiol. Immunol., 282, 31
  133. Posor, 2014, Phosphoinositides in endocytosis, Biochim. Biophys. Acta
  134. Padron, 2003, Phosphatidylinositol phosphate 5-kinase Ibeta recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis, J. Cell Biol., 162, 693, 10.1083/jcb.200302051 · DOI
  135. Zheng, 1996, Identification of the binding site for acidic phospholipids on the pH domain of dynamin: implications for stimulation of GTPase activity, J. Mol. Biol., 255, 14, 10.1006/jmbi.1996.0002 · DOI
  136. Letinic, 2009, Exocyst is involved in polarized cell migration and cerebral cortical development, Proc. Natl. Acad. Sci. U. S. A., 106, 11342, 10.1073/pnas.0904244106 · DOI
  137. Liu, 2012, The exocyst complex in exocytosis and cell migration, Protoplasma, 249, 587, 10.1007/s00709-011-0330-1 · DOI
  138. Xiong, 2012, An association between type Igamma PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization, Mol. Biol. Cell, 23, 87, 10.1091/mbc.E11-05-0449 · DOI
  139. Zhang, 2008, Membrane association and functional regulation of Sec3 by phospholipids and Cdc42, J. Cell Biol., 180, 145, 10.1083/jcb.200704128 · DOI
  140. Liu, 2007, Phosphatidylinositol 4,5-bisphosphate mediates the targeting of the exocyst to the plasma membrane for exocytosis in mammalian cells, Mol. Biol. Cell, 18, 4483, 10.1091/mbc.E07-05-0461 · DOI
  141. Spiczka, 2008, Ral-regulated interaction between Sec5 and paxillin targets exocyst to focal complexes during cell migration, J. Cell Sci., 121, 2880, 10.1242/jcs.031641 · DOI
  142. Wan, 2013, Guidance receptor promotes the asymmetric distribution of exocyst and recycling endosome during collective cell migration, Development, 140, 4797, 10.1242/dev.094979 · DOI
  143. Farre, 2011, Rallying the exocyst as an autophagy scaffold, Cell, 144, 172, 10.1016/j.cell.2011.01.005 · DOI
  144. Heider, 2012, Exorcising the exocyst complex, Traffic, 13, 898, 10.1111/j.1600-0854.2012.01353.x · DOI
  145. Bodemann, 2011, RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly, Cell, 144, 253, 10.1016/j.cell.2010.12.018 · DOI
  146. Pourcher, 2010, Analyses of sorting nexins reveal distinct retromer-subcomplex functions in development and protein sorting in Arabidopsis thaliana, Plant Cell, 22, 3980, 10.1105/tpc.110.078451 · DOI
  147. Verges, 2007, Retromer and sorting nexins in development, Front. Biosci., 12, 3825, 10.2741/2355 · DOI
  148. Schwarz, 2002, Genetic analysis of sorting nexins 1 and 2 reveals a redundant and essential function in mice, Mol. Biol. Cell, 13, 3588, 10.1091/mbc.E02-03-0145 · DOI
  149. Harterink, 2011, A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion, Nat. Cell. Biol., 10.1038/ncb2281 · DOI · Paper page
  150. Yoo, 2006, Snx5, as a mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish, FEBS Lett., 580, 4409, 10.1016/j.febslet.2006.07.009 · DOI
  151. Worby, 2002, Sorting out the cellular functions of sorting nexins, Nat. Rev. Mol. Cell Biol., 3, 919, 10.1038/nrm974 · DOI · Paper page
  152. Carlton, 2005, Sorting nexins, Curr. Biol., 15, R819, 10.1016/j.cub.2005.10.012 · DOI · Paper page
  153. Carlton, 2005, Sorting nexins—unifying trends and new perspectives, Traffic, 6, 75, 10.1111/j.1600-0854.2005.00260.x · DOI
  154. Seet, 2006, The Phox (PX) domain proteins and membrane traffic, Biochim. Biophys. Acta, 1761, 878, 10.1016/j.bbalip.2006.04.011 · DOI
  155. Koharudin, 2009, The phox domain of sorting nexin 5 lacks phosphatidylinositol 3-phosphate, J. Biol. Chem., 284, 23697, 10.1074/jbc.M109.008995 · DOI
  156. Sun, 2013, An unexpected role for PI4,5P 2 in EGF receptor endosomal trafficking, Cell Cycle, 12, 1991, 10.4161/cc.25309 · DOI
  157. Raiborg, 2001, FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes, J. Cell Sci., 114, 2255, 10.1242/jcs.114.12.2255 · DOI
  158. Henne, 2011, The ESCRT pathway, Dev. Cell, 21, 77, 10.1016/j.devcel.2011.05.015 · DOI
  159. Slagsvold, 2005, Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain, J. Biol. Chem., 280, 19600, 10.1074/jbc.M501510200 · DOI
  160. Pylypenko, 2007, The PX-BAR membrane-remodeling unit of sorting nexin 9, EMBO J., 26, 4788, 10.1038/sj.emboj.7601889 · DOI
  161. Shin, 2008, SNX9 regulates tubular invagination of the plasma membrane through interaction with actin cytoskeleton and dynamin 2, J. Cell Sci., 121, 1252, 10.1242/jcs.016709 · DOI
  162. Barlow, 2010, Nuclear phosphoinositides: a signaling enigma wrapped in a compartmental conundrum, Trends Cell Biol., 20, 25, 10.1016/j.tcb.2009.09.009 · DOI
  163. Shah, 2013, Nuclear phosphoinositides and their impact on nuclear functions, FEBS J., 280, 6295, 10.1111/febs.12543 · DOI
  164. Cocco, 1988, Rapid changes in phospholipid metabolism in the nuclei of Swiss 3T3 cells induced by treatment of the cells with insulin-like growth factor I, Biochem. Biophys. Res. Commun., 154, 1266, 10.1016/0006-291X(88)90276-8 · DOI
  165. Divecha, 1991, EMBO J., 10, 3207, 10.1002/j.1460-2075.1991.tb04883.x · DOI
  166. Divecha, 1993, Inositides and the nucleus and inositides in the nucleus, Cell, 74, 405, 10.1016/0092-8674(93)80041-C · DOI
  167. Faenza, 2013, Nuclear inositide specific phospholipase C signalling — interactions and activity, FEBS J., 280, 6311, 10.1111/febs.12450 · DOI
  168. Faenza, 2007, Role of nuclear PLC and PI3K signaling in the development of cancer, Futur. Lipidol., 2, 303, 10.2217/17460875.2.3.303 · DOI
  169. Gonzales, 2006, Nuclear phosphoinositide kinases and inositol phospholipids, J. Cell. Biochem., 97, 252, 10.1002/jcb.20655 · DOI
  170. Kumar, 2011, Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survival, Mol. Biol. Cell, 31, 2122, 10.1128/MCB.01313-10 · DOI
  171. Toska, 2012, Repression of transcription by WT1-BASP1 requires the myristoylation of BASP1 and the PIP2-dependent recruitment of histone deacetylase, Cell Rep., 2, 462, 10.1016/j.celrep.2012.08.005 · DOI
  172. Yu, 1998, Phosphatidylinositol 4,5-bisphosphate reverses the inhibition of RNA transcription caused by histone H1, Eur. J. Biochem., 251, 281, 10.1046/j.1432-1327.1998.2510281.x · DOI
  173. Zhao, 1998, Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling, Cell, 95, 625, 10.1016/S0092-8674(00)81633-5 · DOI
  174. Gonzales, 2008, CKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAs, J. Biol. Chem., 283, 12665, 10.1074/jbc.M800656200 · DOI
  175. Li, 2012, Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIalpha and PKCdelta signaling, Mol. Cell, 45, 25, 10.1016/j.molcel.2011.11.017 · DOI
  176. Mellman, 2008, A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs, Nature, 451, 1013, 10.1038/nature06666 · DOI
  177. Osborne, 2001, Nuclear PtdIns(4,5)P2 assembles in a mitotically regulated particle involved in pre-mRNA splicing, J. Cell Sci., 114, 2501, 10.1242/jcs.114.13.2501 · DOI
  178. Rakesh, 2011, CKI isoforms alpha and epsilon regulate Star‚ÄìPAP target messages by controlling Star-PAP poly(A) polymerase activity and phosphoinositide stimulation, Nucleic Acids Res., 39, 7961, 10.1093/nar/gkr549 · DOI
  179. Jani, 2012, Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export, Nucleic Acids Res., 40, 4562, 10.1093/nar/gks059 · DOI
  180. Okada, 2008, Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY, Proc. Natl. Acad. Sci. U. S. A., 105, 8649, 10.1073/pnas.0802533105 · DOI
  181. Dunaief, 1994, The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest, Cell, 79, 119, 10.1016/0092-8674(94)90405-7 · DOI
  182. Boronenkov, 1998, Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors, Mol. Biol. Cell, 9, 3547, 10.1091/mbc.9.12.3547 · DOI
  183. Wang, 2010, Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIalpha and IIbeta and a partial nuclear localization of the IIalpha isoform, Biochem. J., 430, 215, 10.1042/BJ20100340 · DOI
  184. Bultsma, 2010, PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4Kalpha, Biochem. J., 430, 223, 10.1042/BJ20100341 · DOI
  185. Ciruela, 2000, Nuclear targeting of the beta isoform of type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its alpha-helix 7, Biochem. J., 346, 587, 10.1042/0264-6021:3460587 · DOI
  186. Bunce, 2008, Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate, J. Biol. Chem., 283, 8678, 10.1074/jbc.M710222200 · DOI
  187. Li, 2013, The novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3′-end of mRNAs, Adv. Biol. Regul., 53, 64, 10.1016/j.jbior.2012.10.004 · DOI
  188. Laishram, 2010, The poly A polymerase Star-PAP controls 3′-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA, EMBO J., 29, 4132, 10.1038/emboj.2010.287 · DOI
  189. Gross, 1999, The casein kinase Ialpha isoform is both physically positioned and functionally competent to regulate multiple events of mRNA metabolism, J. Cell Sci., 112, 2647, 10.1242/jcs.112.16.2647 · DOI
  190. O'Brian, 1987, The activation of protein kinase C by the polyphosphoinositides phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-monophosphate, FEBS Lett., 214, 339, 10.1016/0014-5793(87)80083-2 · DOI
  191. Chauhan, 1988, Phosphatidylinositol-4,5-bisphosphate may antecede diacylglycerol as activator of protein kinase C, Biochem. Biophys. Res. Commun., 155, 18, 10.1016/S0006-291X(88)81043-X · DOI
  192. Chauhan, 1989, Phosphatidylinositol 4,5-bisphosphate competitively inhibits phorbol ester binding to protein kinase C, Biochemistry, 28, 4952, 10.1021/bi00438a007 · DOI
  193. Chauhan, 1991, Interaction of protein kinase C with phosphoinositides, Arch. Biochem. Biophys., 287, 283, 10.1016/0003-9861(91)90480-7 · DOI
  194. Li, 2014, Star-PAP controls HPV E6 regulation of p53 and sensitizes cells to VP-16, Oncogene, 33, 928, 10.1038/onc.2013.14 · DOI
  195. Sablin, 2009, Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands, Mol. Endocrinol., 23, 25, 10.1210/me.2007-0508 · DOI
  196. Blind, 2014, The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1, Proc. Natl. Acad. Sci. U. S. A., 111, 15054, 10.1073/pnas.1416740111 · DOI
  197. Blind, 2012, Direct modification and activation of a nuclear receptor-PIP(2) complex by the inositol lipid kinase IPMK, Sci. Signal., 5, ra44, 10.1126/scisignal.2003111 · DOI · Paper page
  198. Nishikawa, 1998, Association of protein kinase Cmu with type II phosphatidylinositol 4-kinase and type I phosphatidylinositol-4-phosphate 5-kinase, J. Biol. Chem., 273, 23126, 10.1074/jbc.273.36.23126 · DOI
  199. Jones, 2000, Type I phosphatidylinositol 4-phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the golgi compartment, J. Biol. Chem., 275, 13962, 10.1074/jbc.C901019199 · DOI
  200. Balla, 2005, A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1, Mol. Biol. Cell, 16, 1282, 10.1091/mbc.E04-07-0578 · DOI

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Metadata

Authors
Choi, S., Thapa, N., Tan, X., Hedman, A. C., & Anderson, R. A.
Venue
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Publisher
Elsevier BV
Published
2015-06
Volume
1851
Issue
6
Pages
711-723
ISSN
1388-1981
DOI
10.1016/j.bbalip.2015.01.009
PMC
PMC4380618
Cited by
75
References
6
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Funders
NIH (CA104708, GM057549)

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