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Sorting out the cellular functions of sorting nexins

Worby, Carolyn A., Dixon, Jack E.·2002·Nature Reviews Molecular Cell Biology
DOI 10.1038/nrm974
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Abstract

Sorting nexins are a diverse group of cellular trafficking proteins that are unified by the presence of a phospholipid-binding motif - the PX domain. The ability of these proteins to bind specific phospholipids, as well as their propensity to form protein-protein complexes, points to a role for these proteins in membrane trafficking and protein sorting. It will be interesting to determine whether the various sorting nexins have specialized or generalized roles in protein trafficking.

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Metadata

Authors
Worby, C. A., & Dixon, J. E.
Venue
Nature Reviews Molecular Cell Biology
Publisher
Springer Science and Business Media LLC
Published
2002-12-01
Volume
3
Issue
12
Pages
919-931
ISSN
  • 1471-0072
  • 1471-0080
DOI
10.1038/nrm974
Cited by
364
References
2
Language
en
Update notices
correction (2003-02-01)
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