Cited by 116Mindfulness and Compassion InterventionsTelomeres, Telomerase, and SenescenceReligion, Spirituality, and Psychology

The DOI matches its Crossref record; 46 of the 47 references it cites were found in a registry or an index.

Loving-Kindness Meditation practice associated with longer telomeres in women

Abstract

Relatively short telomere length may serve as a marker of accelerated aging, and shorter telomeres have been linked to chronic stress. Specific lifestyle behaviors that can mitigate the effects of stress might be associated with longer telomere lengths. Previous research suggests a link between behaviors that focus on the well-being of others, such as volunteering and caregiving, and overall health and longevity. We examined relative telomere length in a group of individuals experienced in Loving-Kindness Meditation (LKM), a practice derived from the Buddhist tradition which utilizes a focus on unselfish kindness and warmth towards all people, and control participants who had done no meditation. Blood was collected by venipuncture, and Genomic DNA was extracted from peripheral blood leukocytes. Quantitative real time PCR was used to measure relative telomere length (RTL) (Cawthon, 2002) in fifteen LKM practitioners and 22 control participants. There were no significant differences in age, gender, race, education, or exposure to trauma, but the control group had a higher mean body mass index (BMI) and lower rates of past depression. The LKM practitioners had longer RTL than controls at the trend level (p=.083); among women, the LKM practitioners had significantly longer RTL than controls, (p=.007), which remained significant even after controlling for BMI and past depression. Although limited by small sample size, these results offer the intriguing possibility that LKM practice, especially in women, might alter RTL, a biomarker associated with longevity.

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Crossref · 10.1016/j.bbi.2013.04.005

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Metadata

Authors
Hoge, E. A., Chen, M. M., Orr, E., Metcalf, C. A., Fischer, L. E., Pollack, M. H., DeVivo, I., & Simon, N. M.
Affiliations
  • Harvard University (US)
  • Rush University Medical Center (US)
Corresponding author
Hoge, Elizabeth A.
Venue
Brain, Behavior, and Immunity
Publisher
Elsevier BV
Published
2013-08
Volume
32
Pages
159-163
ISSN
0889-1591 (ISSN-L)
OpenAlex
W2052944489
Cited by
116
References
47
Citations by year
2025: 3 · 2024: 6 · 2023: 11 · 2022: 10 · 2021: 11 · 2020: 12 · 2019: 11 · 2018: 10 · 2017: 8 · 2016: 9 · 2015: 8 · 2014: 12 · 2013: 5
FWCI
12.50
Type
journal article
Language
en
Open access
closed
Locations
  • Brain Behavior and Immunity (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institutes of Health Award (8UL1TR000170-05)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
  • Social Sciences › Health › Religion, Spirituality, and Psychology
Keywords
loving-kindness meditation, telomere length, relative telomere length, accelerated aging, women, Buddhist meditation, longevity, aging biomarkers, stress, body mass index, depression
MeSH terms
Adult, Data Interpretation, Statistical, DNA, Female, Humans, Leukocytes, Love, Male, Middle Aged, Body Mass Index, Polymerase Chain Reaction, Telomere, Meditation

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