Novelty seeking, incentive salience and acquisition of cocaine self-administration in the rat

The Neural Basis of Addiction: A Pathology of Motivation and Choice

Kalivas, P. W., & Volkow, N. D. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.8.1403 · Cited by 2,757 · see citing works

Untitled work

(1994) · Cited by 2,675 · see citing works

AUTO‐SHAPING OF THE PIGEON'S KEY‐PECK1

Brown, P. L., & Jenkins, H. M. (1968) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.1968.11-1 · Cited by 1,544 · see citing works

Behavioral expressions and biosocial bases of sensation seeking

Corr, P. J. (1995) · Personality and Individual Differences · doi:10.1016/0191-8869(95)90059-4 · Cited by 1,525 · see citing works

Factors That Predict Individual Vulnerability to Amphetamine Self-Administration

Piazza, P. V., Deminière, J.-M., Moal, M. L., & Simon, H. (1989) · Science · doi:10.1126/science.2781295 · Cited by 1,355 · see citing works

The role of impulsive behavior in drug abuse

Perry, J. L., & Carroll, M. E. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1173-0 · Cited by 805 · see citing works

Bivariate median splits and spurious statistical significance.

Maxwell, S. E., & Delaney, H. D. (1993) · Psychological Bulletin · doi:10.1037/0033-2909.113.1.181 · Cited by 661 · see citing works

Neurobiological mechanisms in the transition from drug use to drug dependence

Koob, G. F., Ahmed, S. H., Boutrel, B., Chen, S. A., Kenny, P. J., Markou, A., O’Dell, L. E., Parsons, L. H., & Sanna, P. P. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2003.11.007 · Cited by 576 · see citing works

Corticosterone levels determine individual vulnerability to amphetamine self-administration.

Piazza, P. V., Maccari, S., Deminière, J.-M., Moal, M. L., Mormède, P., & Simon, H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.6.2088 · Cited by 567 · see citing works

Individual differences in the attribution of incentive salience to reward-related cues: implications for addiction

Flagel, S. B., Akil, H., & Robinson, T. E. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.06.027 · Cited by 561 · see citing works

Operant-Pavlovian Interactions

Davis, H., & Hurwitz, H. M. B. (2021) · Routledge eBooks · doi:10.4324/9781003150404 · Cited by 509 · see citing works

Novelty seeking, risk taking, and related constructs as predictors of adolescent substance use: An application of Cloninger's theory

Wills, T. A., Vaccaro, D., & McNamara, G. (1994) · Journal of Substance Abuse · doi:10.1016/s0899-3289(94)90039-6 · Cited by 480 · see citing works

Dissociating the Predictive and Incentive Motivational Properties of Reward-Related Cues Through the Study of Individual Differences

Robinson, T. E., & Flagel, S. B. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.006 · Cited by 416 · see citing works

Novelty-Seeking in Rats-Biobehavioral Characteristics and Possible Relationship with the Sensation-Seeking Trait in Man

Dellu-Hagedorn, F., Piazza, P. V., Mayo, W., Moal, M. L., & Simon, H. (2008) · Neuropsychobiology · doi:10.1159/000119305 · Cited by 394 · see citing works

Impulsivity (delay discounting) as a predictor of acquisition of IV cocaine self-administration in female rats

Perry, J. L., Larson, E. B., German, J. P., Madden, G. J., & Carroll, M. E. (2005) · Psychopharmacology · doi:10.1007/s00213-004-1994-4 · Cited by 388 · see citing works

Neurobiological Correlates of Individual Differences in Novelty-Seeking Behavior in the Rat: Differential Expression of Stress-Related Molecules

Kabbaj, M., Devine, D. P., Savage, V. R., & Akil, H. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-18-06983.2000 · Cited by 350 · see citing works

An Animal Model of Genetic Vulnerability to Behavioral Disinhibition and Responsiveness to Reward-Related Cues: Implications for Addiction

Flagel, S. B., Robinson, T. E., Clark, J. J., Clinton, S. M., Watson, S. J., Seeman, P., Phillips, P. E. M., & Akil, H. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.142 · Cited by 339 · see citing works

Individual differences in the propensity to approach signals vs goals promote different adaptations in the dopamine system of rats

Flagel, S. B., Watson, S. J., Robinson, T. E., & Akil, H. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0535-8 · Cited by 290 · see citing works

A Cocaine Cue Acts as an Incentive Stimulus in Some but not Others: Implications for Addiction

Saunders, B. T., & Robinson, T. E. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.11.015 · Cited by 271 · see citing works

Enhanced Vulnerability to Cocaine Self-Administration Is Associated with Elevated Impulse Activity of Midbrain Dopamine Neurons

Marinelli, M., & White, F. J. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-23-08876.2000 · Cited by 254 · see citing works

Regional and temporal differences in real-time dopamine efflux in the nucleus accumbens during free-choice novelty

Rebec, G. V., Christensen, J. R. C., Guerra, C., & Bardo, M. T. (1997) · Brain Research · doi:10.1016/s0006-8993(97)01004-4 · Cited by 235 · see citing works

Temperament and novelty seeking in adolescent substance use: Convergence of dimensions of temperament with constructs from Cloninger's theory.

Wills, T. A., Windle, M. T., & Cleary, S. D. (1998) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.74.2.387 · Cited by 229 · see citing works

Temperament and novelty seeking in adolescent substance use: Convergence of dimensions of temperament with constructs from Cloninger's theory.

Wills, T. A., Windle, M. T., & Cleary, S. D. (1998) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.74.2.387 · Cited by 205 · see citing works

Predisposition to self-administer amphetamine: the contribution of response to novelty and prior exposure to the drug

Pierre, P. J., & Vezina, P. (1997) · Psychopharmacology · doi:10.1007/s002130050191 · Cited by 197 · see citing works

The role of mesoaccumbens-pallidal circuitry in novelty-induced behavioral activation

Hooks, M. S., & Kalivas, P. W. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00409-x · Cited by 180 · see citing works

Behavioral characteristics and neurobiological substrates shared by Pavlovian sign-tracking and drug abuse

Tomie, A., Grimes, K. L., & Pohorecky, L. A. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.12.003 · Cited by 176 · see citing works

Acquisition of IV amphetamine and cocaine self-administration in rats as a function of dose

Carroll, M. E., & Lac, S. T. (1997) · Psychopharmacology · doi:10.1007/s002130050182 · Cited by 162 · see citing works

Individual differences in behavioral responses to novelty and amphetamine self-administration in male and female rats

Klebaur, J. E., Bevins, R. A., Segar, T. M., & Bardo, M. T. (2001) · Behavioural Pharmacology · doi:10.1097/00008877-200107000-00005 · Cited by 140 · see citing works

Individual differences in drug abuse vulnerability: d-Amphetamine and sensation-seeking status

Kelly, T., Robbins, G., Martin, C. A., Fillmore, M., Lane, S., Harrington, N., & Rush, C. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0487-z · Cited by 134 · see citing works

Effects of isolation, handling and novelty on the pituitary-adrenal response in the mouse

Misslin, R., Herzog, F., Koch, B., & Ropartz, P. (1982) · Psychoneuroendocrinology · doi:10.1016/0306-4530(82)90015-4 · Cited by 121 · see citing works

Novelty seeking and drug use: Contribution of an animal model.

Cain, M. E., Saucier, D. A., & Bardo, M. T. (2005) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.13.4.367 · Cited by 120 · see citing works

Novelty-induced place preference behavior in rats: Effects of opiate and dopaminergic drugs

Bardo, M. T., Neisewander, J. L., & Pierce, R. C. (1989) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(89)90018-x · Cited by 116 · see citing works

Ethanol induces impulsive-like responding in a delay-of-reward operant choice procedure: impulsivity predicts autoshaping

Tomie, A., Aguado, A. S., Pohorecky, L. A., & Benjamin, D. (1998) · Psychopharmacology · doi:10.1007/s002130050728 · Cited by 108 · see citing works

Animal models of drug addiction: Where do we go from here?

Olmstead, M. C. (2006) · Quarterly Journal of Experimental Psychology · doi:10.1080/17470210500356308 · Cited by 108 · see citing works

Effects of clomipramine on self-control choice in Lewis and Fischer 344 rats

Anderson, K. G., & Woolverton, W. L. (2005) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2004.11.015 · Cited by 106 · see citing works

The reinforcing, subject-rated, performance, and cardiovascular effects of d-amphetamine: Influence of sensation-seeking status

Stoops, W. W., Lile, J. A., Robbins, C. G., Martin, C. A., Rush, C. R., & Kelly, T. H. (2006) · Addictive Behaviors · doi:10.1016/j.addbeh.2006.08.006 · Cited by 87 · see citing works

Individual Differences in Vulnerability to Drug Abuse: The High Responders/Low Responders Model

Kabbaj, M. (2006) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152706778559318 · Cited by 83 · see citing works

Individual Differences in Pavlovian Autoshaping of Lever Pressing in Rats Predict Stress-Induced Corticosterone Release and Mesolimbic Levels of Monoamines

Tomie, A., Aguado, A., Pohorecky, L. A., & Benjamin, D. (2000) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(99)00241-5 · Cited by 78 · see citing works

Differences in impulsivity on a delay-discounting task predict self-administration of a low unit dose of methylphenidate in rats

Marusich, J. A., & Bardo, M. T. (2009) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e328330ad6d · Cited by 72 · see citing works

STEADY‐STATE ASSESSMENT OF IMPULSIVE CHOICE IN LEWIS AND FISCHER 344 RATS: BETWEEN‐CONDITION DELAY MANIPULATIONS

Madden, G. J., Smith, N. G., Brewer, A. T., Pinkston, J. W., & Johnson, P. S. (2008) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.2008.90-333 · Cited by 66 · see citing works

Mixed effects modeling of Morris water maze data: Advantages and cautionary notes

Young, M. E., Clark, M. H., Goffus, A. M., & Hoane, M. R. (2008) · Learning and Motivation · doi:10.1016/j.lmot.2008.10.004 · Cited by 55 · see citing works

The effect of novelty on amphetamine self-administration in rats classified as high and low responders

Cain, M. E., Smith, C. M., & Bardo, M. T. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1870-2 · Cited by 53 · see citing works

Pavlovian autoshaping procedures increase plasma corticosterone and levels of norepinephrine and serotonin in prefrontal cortex in rats

Tomie, A., Tirado, A. D., Yu, L., & Pohorecky, L. A. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.11.006 · Cited by 49 · see citing works

Individual Differences in Amphetamine Self-Administration: The Role of the Central Nucleus of the Amygdala

Cain, M. E., Denehy, E. D., & Bardo, M. T. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301478 · Cited by 46 · see citing works

A comparison of Lewis and Fischer rat strains on autoshaping (sign-tracking), discrimination reversal learning and negative automaintenance

Kearns, D. N., Gomez-Serrano, M. A., Weiss, S. J., & Riley, A. L. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.01.005 · Cited by 43 · see citing works

Escalation of food-maintained responding and sensitivity to the locomotor stimulant effects of cocaine in mice

Goeders, J. E., Murnane, K. S., Banks, M. L., & Fantegrossi, W. E. (2009) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2009.04.008 · Cited by 35 · see citing works

Performance and subjective effects of diazepam and d-amphetamine in high and low sensation seekers

Kelly, T. H., Delzer, T. A., Martin, C. A., Harrington, N. G., Hays, L. R., & Bardo, M. T. (2009) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3283305e8d · Cited by 30 · see citing works

Effect of rate of delivery of intravenous cocaine on self-administration in rats

Schindler, C. W., Panlilio, L. V., & Thorndike, E. B. (2009) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2009.05.008 · Cited by 28 · see citing works

Dissociation of core and shell single-unit activity in the nucleus accumbens in free-choice novelty

Wood, D. (2003) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.09.038 · Cited by 23 · see citing works

A selective role for dopamine in stimulus-reward learning

Flagel, S. B., Clark, J. J., Robinson, T. E., Mayo, L., Czuj, A., Willuhn, I., Akers, C. A., Clinton, S. M., Phillips, P. E. M., & Akil, H. (2011) · Nature · doi:10.1038/nature09588 · Cited by 1,026 · see citing works

The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis

Scofield, M. D., Heinsbroek, J. A., Gipson, C. D., Kupchik, Y. M., Spencer, S., Smith, A. C. W., Roberts-Wolfe, D., & Kalivas, P. W. (2016) · Pharmacological Reviews · doi:10.1124/pr.116.012484 · Cited by 598 · see citing works

Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use

Bock, R., Shin, J. H., Kaplan, A. R., Dobi, A., Markey, E., Kramer, P. F., Gremel, C. M., Christensen, C. H., Adrover, M. F., & Alvarez, V. A. (2013) · Nature Neuroscience · doi:10.1038/nn.3369 · Cited by 307 · see citing works

Quantifying Individual Variation in the Propensity to Attribute Incentive Salience to Reward Cues

Meyer, P., Lovic, V., Saunders, B. T., Yager, L. M., Flagel, S. B., Morrow, J. D., & Robinson, T. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038987 · Cited by 296 · see citing works

High-Novelty-Preference Rats are Predisposed to Compulsive Cocaine Self-administration

Belin, D., Berson, N., Balado, É., Piazza, P. V., & Deroche‐Gamonet, V. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.188 · Cited by 255 · see citing works

On the Motivational Properties of Reward Cues: Individual Differences

Robinson, T., Yager, L. M., Cogan, E. S., & Saunders, B. T. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.05.040 · Cited by 249 · see citing works

Aberrant learning and memory in addiction

Torregrossa, M. M., Corlett, P. R., & Taylor, J. R. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.02.014 · Cited by 223 · see citing works

Less is more: prolonged intermittent access cocaine self-administration produces incentive-sensitization and addiction-like behavior

Kawa, A. B., Bentzley, B. S., & Robinson, T. E. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4393-8 · Cited by 208 · see citing works

Stress in adolescence and drugs of abuse in rodent models: role of dopamine, CRF, and HPA axis

Burke, A. R., & Miczek, K. A. (2014) · Psychopharmacology · doi:10.1007/s00213-013-3369-1 · Cited by 207 · see citing works

Individual Variation in the Motivational Properties of Cocaine

Saunders, B. T., & Robinson, T. E. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.48 · Cited by 206 · see citing works

Structural and functional plasticity of dendritic spines – root or result of behavior?

Gipson, C. D., & Olive, M. F. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12324 · Cited by 192 · see citing works

Understanding Addiction Using Animal Models

Kuhn, B. N., Kalivas, P. W., & Bobadilla, A. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00262 · Cited by 171 · see citing works

Individual Differences and Social Influences on the Neurobehavioral Pharmacology of Abused Drugs

Bardo, M. T., Neisewander, J. L., & Kelly, T. H. (2013) · Pharmacological Reviews · doi:10.1124/pr.111.005124 · Cited by 167 · see citing works

Individual variation in resisting temptation: Implications for addiction

Saunders, B. T., & Robinson, T. E. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.02.008 · Cited by 165 · see citing works

A food predictive cue must be attributed with incentive salience for it to induce c-fos mRNA expression in cortico-striatal-thalamic brain regions

Flagel, S. B., Cameron, C., Pickup, K. N., Watson, S. J., Akil, H., & Robinson, T. E. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.09.004 · Cited by 153 · see citing works

Novelty, conditioning and attentional bias to sexual rewards

Banca, P., Morris, L. S., Mitchell, S., Harrison, N. A., Potenza, M. N., & Voon, V. (2016) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.10.017 · Cited by 137 · see citing works

Incentive Motivation, Cognitive Control, and the Adolescent Brain: Is It Time for a Paradigm Shift?

Luciana, M., & Collins, P. F. (2012) · Child Development Perspectives · doi:10.1111/j.1750-8606.2012.00252.x · Cited by 123 · see citing works

Rats that sign-track are resistant to Pavlovian but not instrumental extinction

Ahrens, A. M., Singer, B. F., Fitzpatrick, C. J., Morrow, J. D., & Robinson, T. E. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.07.055 · Cited by 112 · see citing works

How foraging works: Uncertainty magnifies food-seeking motivation

Anselme, P., & Güntürkün, O. (2018) · Behavioral and Brain Sciences · doi:10.1017/s0140525x18000948 · Cited by 103 · see citing works

A cocaine cue is more preferred and evokes more frequency-modulated 50-kHz ultrasonic vocalizations in rats prone to attribute incentive salience to a food cue

Meyer, P., Ma, S. T., & Robinson, T. E. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2429-7 · Cited by 93 · see citing works

The role of learning-related dopamine signals in addiction vulnerability

Huys, Q. J. M., Tobler, P. N., Hasler, G., & Flagel, S. B. (2014) · Progress in brain research · doi:10.1016/b978-0-444-63425-2.00003-9 · Cited by 87 · see citing works

Early-life adversity facilitates acquisition of cocaine self-administration and induces persistent anhedonia

Bolton, J. L., Ruiz, C. M., Rismanchi, N., Sanchez, G. A., Castillo, E., Huang, J. J., Cross, C., Baram, T. Z., & Mahler, S. V. (2018) · Neurobiology of Stress · doi:10.1016/j.ynstr.2018.01.002 · Cited by 91 · see citing works

Sign-tracking predicts increased choice of cocaine over food in rats

Tunstall, B. J., & Kearns, D. N. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.12.034 · Cited by 76 · see citing works

Behavioral endophenotypes of drug addiction: Etiological insights from neuroimaging studies

Jupp, B., & Dalley, J. W. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.05.041 · Cited by 77 · see citing works

Isolating the incentive salience of reward-associated stimuli: value, choice, and persistencePreprint

Beckmann, J. S., & Chow, J. J. (2015) · Learning & Memory · doi:10.1101/lm.037382.114 · Cited by 73 · see citing works

A potential role for the paraventricular nucleus of the thalamus in mediating individual variation in Pavlovian conditioned responses

Haight, J. L., & Flagel, S. B. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00079 · Cited by 71 · see citing works

Environmental enrichment reduces attribution of incentive salience to a food-associated stimulus

Beckmann, J. S., & Bardo, M. T. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.09.021 · Cited by 61 · see citing works

Inter-individual diversity and intra-individual stability of amphetamine-induced sensitization of frequency-modulated 50-kHz vocalization in Sprague–Dawley rats

Taracha, E., Hamed, A., Krząścik, P., Lehner, M., Skórzewska, A., Płaźnik, A., & Chrapusta, S. J. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2658-4 · Cited by 58 · see citing works

Incentive salience attribution, “sensation-seeking” and “novelty-seeking” are independent traits in a large sample of male and female heterogeneous stock rats

Netzley, A. H., Horvath, A. P., Holl, K., Palmer, A. A., Woods, L. C. S., Robinson, T. E., & Flagel, S. B. (2019) · Scientific Reports · doi:10.1038/s41598-019-39519-1 · Cited by 58 · see citing works

PYY3–36: Beyond food intake

Weber‐Stadlbauer, U., Woods, S. C., Langhans, W., & Meyer, U. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.12.003 · Cited by 53 · see citing works

Capacity of novelty-induced locomotor activity and the hole-board test to predict sensitivity to the conditioned rewarding effects of cocaine

Arenas, M. C., Daza‐Losada, M., Vidal‐Infer, A., Aguilar, M. A., Miñarro, J., & Rodríguez‐Arias, M. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.05.028 · Cited by 51 · see citing works

Effects of adolescent social defeat on adult amphetamine-induced locomotion and corticoaccumbal dopamine release in male rats

Burke, A. R., Forster, G. L., Novick, A. M., Roberts, C. L., & Watt, M. J. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.11.013 · Cited by 49 · see citing works

From sign-tracking to attentional bias: Implications for gambling and substance use disorders

Anselme, P., & Robinson, M. J. F. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.109861 · Cited by 41 · see citing works

Environmental enrichment reduces methamphetamine cue-induced reinstatement but does not alter methamphetamine reward or VMAT2 function

Hofford, R. S., Darna, M., Wilmouth, C. E., Dwoskin, L. P., & Bardo, M. T. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.007 · Cited by 42 · see citing works

Rats classified as low or high cocaine locomotor responders: A unique model involving striatal dopamine transporters that predicts cocaine addiction-like behaviors

Yamamoto, D. J., Nelson, A. M., Mandt, B. H., Larson, G. A., Rorabaugh, J. M., Ng, C. M. C., Barcomb, K., Richards, T. L., Allen, R. M., & Zahniser, N. R. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.07.002 · Cited by 41 · see citing works

Animal Models of Drug Addiction

Belin‐Rauscent, A., & Belin, D. (2012) · InTech eBooks · doi:10.5772/52079 · Cited by 39 · see citing works

Association of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice

Dickson, P. E., Ndukum, J., Wilcox, T. D., Clark, J., Roy, B. D., Zhang, L., Li, Y., Lin, D., & Chesler, E. J. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3737-5 · Cited by 37 · see citing works

Toward isolating the role of dopamine in the acquisition of incentive salience attribution

Chow, J. J., Nickell, J. R., Darna, M., & Beckmann, J. S. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.06.028 · Cited by 36 · see citing works

Drug specificity in drug versus food choice in male rats.

Tunstall, B. J., Riley, A. L., & Kearns, D. N. (2014) · Experimental and Clinical Psychopharmacology · doi:10.1037/a0037019 · Cited by 33 · see citing works

Sensitivity to food and cocaine cues are independent traits in a large sample of heterogeneous stock rats

King, C. P., Tripi, J. A., Netzley, A. H., Horvath, A. P., Lamparelli, A. C., Holl, K. L., Chitre, A. S., Polesskaya, O., Ishiwari, K., Woods, L. C. S., et al. (2021) · Scientific Reports · doi:10.1038/s41598-020-80798-w · Cited by 32 · see citing works

Influence of the Novelty-Seeking Endophenotype on the Rewarding Effects of Psychostimulant Drugs in Animal Models

Arenas, M. C., Aguilar, M. A., Montagud‐Romero, S., Mateos-García, A., Navarro-Francés, C. I., Miñarro, J., & Rodríguez‐Arias, M. (2015) · Current Neuropharmacology · doi:10.2174/1570159x13666150921112841 · Cited by 33 · see citing works

Environmental manipulations alter age differences in attribution of incentive salience to reward-paired cues

Anderson, R. I., Bush, P. C., & SPEAR, L. P. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.09.021 · Cited by 33 · see citing works

Pavlovian Sign-Tracking Model of Alcohol Abuse

Tomie, A., & Sharma, N. (2014) · Current Drug Abuse Reviews · doi:10.2174/18744737113069990023 · Cited by 31 · see citing works

Sex-dependent impact of early-life stress and adult immobilization in the attribution of incentive salience in rats

Fuentes, S., Carrasco, J., Hatto, A., Navarro, J. T., Armario, A., Monsonet, M., Ortiz, J., & Nadal, R. A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190044 · Cited by 29 · see citing works

Transient inactivation of the paraventricular nucleus of the thalamus enhances cue-induced reinstatement in goal-trackers, but not sign-trackers

Kuhn, B. N., Klumpner, M. S., Covelo, I. R., Campus, P., & Flagel, S. B. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4816-1 · Cited by 35 · see citing works

Sex and strain influence attribution of incentive salience to reward cues in mice

Dickson, P. E., McNaughton, K. A., Hou, L., Anderson, L. C., Long, K. H., & Chesler, E. J. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.05.039 · Cited by 30 · see citing works

Paradoxical tolerance to cocaine after initial supersensitivity in drug‐use‐prone animals

Ferris, M. J., Calipari, E. S., Melchior, J. R., Roberts, D. C. S., España, R. A., & Jones, S. R. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12266 · Cited by 28 · see citing works

The Y2 receptor agonist PYY3–36 increases the behavioural response to novelty and acute dopaminergic drug challenge in mice

Weber‐Stadlbauer, U., Weber, E., Langhans, W., & Meyer, U. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713001223 · Cited by 27 · see citing works

Early life adversity potentiates expression of addiction-related traits

Hynes, T. J., Thomas, C. S., Zumbusch, A. S., Samson, A., Petriman, I., Mrdja, U., Orr, A., Cutts, E., Ruzindana, B. G., Hazari, A., et al. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.09.005 · Cited by 24 · see citing works

Individual differences in food cue responsivity are associated with acute and repeated cocaine-induced vocalizations, but not cue-induced vocalizations

Tripi, J. A., Dent, M. L., & Meyer, P. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4476-6 · Cited by 23 · see citing works

How unpredictable access to food increases the body fat of small passerines: A mechanistic approach

Anselme, P., Otto, T., & Güntürkün, O. (2017) · Behavioural Processes · doi:10.1016/j.beproc.2017.08.013 · Cited by 22 · see citing works

Diurnal rhythms in cholinergic modulation of rapid dopamine signals and associative learning in the striatum

Stowe, T. A., Pitts, E. G., Leach, A. C., Iacino, M. C., Niere, F., Graul, B., Raab‐Graham, K. F., Yorgason, J. T., & Ferris, M. J. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110633 · Cited by 22 · see citing works

Individual Differences Are More Than a Gene × Environment Interaction: The Role of Learning

Byrom, N., & Murphy, R. (2018) · Journal of Experimental Psychology: Animal Learning and Cognition · doi:10.1037/xan0000157 · Cited by 20 · see citing works

Increased Goal Tracking in Adolescent Rats Is Goal-Directed and Not Habit-Like

Rode, A., Moghaddam, B., & Morrison, S. E. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00291 · Cited by 22 · see citing works

Comparison of cigarette, little cigar, and waterpipe tobacco smoke condensate and e-cigarette aerosol condensate in a self-administration model

Marusich, J. A., Wiley, J. L., Silinski, M. A. R., Thomas, B. F., Meredith, S. E., Gahl, R. F., & Jackson, K. J. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112061 · Cited by 18 · see citing works

Risk-promoting effects of reward-paired cues in human sign- and goal-trackers

Cherkasova, M. V., Clark, L., Barton, J. J. S., Stoessl, A. J., & Winstanley, C. A. (2024) · Behavioural Brain Research · doi:10.1016/j.bbr.2024.114865 · Cited by 19 · see citing works

Effects of Social Isolation on Perineuronal Nets in the Amygdala Following a Reward Omission Task in Female Rats

Vazquez-Sanroman, D. B., Wilson, G. A., & Bardo, M. T. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-02125-8 · Cited by 17 · see citing works

Behavioral predictors of individual differences in opioid addiction vulnerability as measured using i.v. self-administration in rats

Swain, Y., Gewirtz, J. C., & Harris, A. C. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.108561 · Cited by 18 · see citing works

Melatonin attenuates morphine‐induced conditioned place preference in Wistar rats

Alshehri, F. S., Alghamdi, B. S. A., Hakami, A. Y., Alshehri, A. A., & Althobaiti, Y. S. (2021) · Brain and Behavior · doi:10.1002/brb3.2397 · Cited by 16 · see citing works

VIPergic neurons of the infralimbic and prelimbic cortices control palatable food intake through separate cognitive pathways

Newmyer, B. A., Whindleton, C. M., Klein, P., Beenhakker, M. P., Jones, M., & Scott, M. M. (2019) · JCI Insight · doi:10.1172/jci.insight.126283 · Cited by 15 · see citing works

Harmonic and frequency modulated ultrasonic vocalizations reveal differences in conditioned and unconditioned reward processing

Garcia, E. J., Mccowan, T. J., & Cain, M. E. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.03.049 · Cited by 15 · see citing works

Investigating discriminative stimulus modulation of opioid seeking after conflict-induced abstinence in sign- and goal-tracking rats

Martin, D. A., Keefer, S. E., & Calu, D. J. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06204-7 · Cited by 14 · see citing works

A glucocorticoid receptor antagonist reduces sign-tracking behavior in male Japanese quail.

Rice, B. A., Eaton, S. E., Prendergast, M., & Akins, C. K. (2018) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000195 · Cited by 14 · see citing works

Implementations of sign- and goal-tracking behavior in humans: A scoping review

Heck, M., Durieux, N., Anselme, P., & Quertemont, É. (2024) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-024-01230-8 · Cited by 12 · see citing works

The role of glutamate signaling in incentive salience: second‐by‐second glutamate recordings in awake Sprague‐Dawley rats

Batten, S. R., Pomerleau, F., Quintero, J. E., Gerhardt, G. A., & Beckmann, J. S. (2018) · Journal of Neurochemistry · doi:10.1111/jnc.14298 · Cited by 12 · see citing works

A mechanical task for measuring sign- and goal-tracking in humans: A proof-of-concept study

Cope, L. M., Gheidi, A., Martz, M. E., Duval, E. R., Khalil, H., Allerton, T., & Morrow, J. D. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.114112 · Cited by 13 · see citing works

Novelty response and 50 kHz ultrasonic vocalizations: Differential prediction of locomotor and affective response to amphetamine in Sprague-Dawley rats

Garcia, E. J., & Cain, M. E. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4132-6 · Cited by 11 · see citing works

Foraging motivation favors the occurrence of Lévy walks

Anselme, P., Otto, T., & Güntürkün, O. (2017) · Behavioural Processes · doi:10.1016/j.beproc.2017.12.014 · Cited by 10 · see citing works

Genetic Loci Influencing Cue‐Reactivity in Heterogeneous Stock Rats

King, C. P., Chitre, A. S., Leal‐Gutiérrez, J. D., Tripi, J. A., Netzley, A. H., Horvath, A. P., Lamparelli, A. C., George, A. M., Martin, C. D., Pierre, C. L. S., et al. (2025) · Genes Brain & Behavior · doi:10.1111/gbb.70018 · Cited by 8 · see citing works

Repeated subcutaneous administration of PT150 has dose-dependent effects on sign tracking in male Japanese quail.

Rice, B. A., Saunders, M. A., Jagielo-Miller, J. E., Prendergast, M., & Akins, C. K. (2019) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000275 · Cited by 9 · see citing works

Resting-state brain activation patterns and network topology distinguish human sign and goal trackers

Schettino, M., Mauti, M., Parrillo, C., Ceccarelli, I., Giove, F., Napolitano, A., Ottaviani, C., Martelli, M., & Orsini, C. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03162-w · Cited by 8 · see citing works

Understanding the shift to compulsion in addiction: insights from personality traits, social factors, and neurobiology

Su, H., Ye, T., Cao, S., & Hu, C. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1416222 · Cited by 8 · see citing works

Repeated Cocaine Intake Differentially Impacts Striatal D2/3 Receptor Availability, Psychostimulant-Induced Dopamine Release, and Trait Behavioral Markers of Drug Abuse

Urueña‐Méndez, G., Dimiziani, A., Bellés, L., Goutaudier, R., & Ginovart, N. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713238 · Cited by 7 · see citing works

Exploration of a novel object in late adolescence predicts novelty-seeking behavior in adulthood: Associations among behavioral responses in four novelty-seeking tests

Cuenya, L., Sabariego, M., Donaire, R., Callejas-Aguilera, J. E., Torres, C., & Fernández‐Teruel, A. (2016) · Behavioural Processes · doi:10.1016/j.beproc.2016.02.003 · Cited by 8 · see citing works

Toward isolating reward changes in diet-induced obesity: A demand analysis

Batten, S. R., Hicks, K., Dwoskin, L. P., & Beckmann, J. S. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.112729 · Cited by 8 · see citing works

Constraint theory: A cognitive, motivational theory of dependence

Hammersley, R. (2013) · Addiction Research & Theory · doi:10.3109/16066359.2013.779678 · Cited by 7 · see citing works

Neural Basis of Drug Addiction

Gipson, C. D., & Kalivas, P. W. (2015) · Springer eBooks · doi:10.1007/978-3-319-17795-3_4 · Cited by 6 · see citing works

Modelling Differential Vulnerability to Substance Use Disorder in Rodents: Neurobiological Mechanisms

Jupp, B., Jones, J. A., & Dalley, J. W. (2019) · Handbook of experimental pharmacology · doi:10.1007/164_2019_300 · Cited by 6 · see citing works

Time-dependent changes in cognitive flexibility performance during intermittent social stress: Relevance for motivation and reward-seeking behavior

Sullivan, L. J., Shaffer, H., Hill, C., & Arco, A. D. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.111972 · Cited by 6 · see citing works

Novelty preference does not predict trait cocaine behaviors in male rats

O’Connor, S. L., Aston‐Jones, G., & James, M. H. (2022) · Addiction Neuroscience · doi:10.1016/j.addicn.2022.100013 · Cited by 6 · see citing works

Comment on Pohorala et al.: Sign-tracking as a predictor of addiction vulnerability

Flagel, S. B., Robinson, T. E., & Sarter, M. F. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05927-3 · Cited by 6 · see citing works

Effects of the cannabinoid receptor agonist CP-55,940 on incentive salience attribution

Gheidi, A., Cope, L. M., Fitzpatrick, C. J., Froehlich, B., Atkinson, R., Groves, C. K., Barcelo, C. N., & Morrow, J. D. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05571-3 · Cited by 5 · see citing works

Individual variation in the attribution of incentive salience to social cues

Fitzpatrick, C. J., & Morrow, J. D. (2020) · Scientific Reports · doi:10.1038/s41598-020-59378-5 · Cited by 4 · see citing works

Novelty preferences and cocaine-associated cues influence regions associated with the salience network in juvenile female rats

Rohan, M. L., Lowen, S. B., Rock, A., & Andersen, S. L. (2021) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2021.173117 · Cited by 4 · see citing works

The Role of D1 Dopamine Receptors on Incentive Salience Attribution

Chow, J. J. (2012) · UKnowledge (University of Kentucky) · Cited by 3 · see citing works

Disrupted Neuronal Dynamics of Reward Encoding in the Medial Prefrontal Cortex and the Ventral Tegmental Area after Episodic Social Stress

Harris, H. M., Woods, A., Chen, Y., & Arco, A. D. (2025) · eNeuro · doi:10.1523/eneuro.0229-25.2025 · Cited by 2 · see citing works

Adolescent neurocognitive development and cannabis use

Tervo‐Clemmens, B., Musket, C. W., Calabro, F. J., & Luna, B. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-817986-4.00046-8 · Cited by 1 · see citing works

Fentanyl reinstatement to discriminative cues after conflict in sign- and goal-tracking ratsPreprint

Martin, D. A., Keefer, S. E., & Calu, D. J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.10.479913 · Cited by 2 · see citing works

Self-administration acquisition latency predicts locomotor sensitivity to cocaine in male rats

Rakela, S., Sortman, B. W., Gobin, C. M., Hao, S., Caceres-Brun, D., & Warren, B. L. (2024) · Behavioural Brain Research · doi:10.1016/j.bbr.2024.115170 · Cited by 1 · see citing works

A Distinct Adolescent Profile for Activity and Dopamine Release in the Nucleus Accumbens during Pavlovian Conditioning

Herring, E. W., Hafenbreidel, M., Patel, E. D., Zeng, S., Syamala, T., Kupelian, P., Torregrossa, M. M., & Morrison, S. E. (2026) · eNeuro · doi:10.1523/eneuro.0173-26.2026 · Cited by 1 · see citing works

The effects of sleep restriction during abstinence on oxycodone seeking: Sex-dependent moderating effects of behavioral and hypothalamic-pituitary-adrenal axis-related phenotypes

Olsen, C. M., Glaeser, B., Szabó, A., Raff, H., & Everson, C. A. (2023) · Physiology & Behavior · doi:10.1016/j.physbeh.2023.114372 · Cited by 1 · see citing works

Incentive salience attribution, “sensation-seeking” and “novelty-seeking” are independent traits in a large sample of male and female heterogeneous stock ratsPreprint

Netzley, A. H., Horvath, A. P., Holl, K., Palmer, A. A., Woods, L. C. S., Robinson, T. E., & Flagel, S. B. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/421065 · Cited by 1 · see citing works

Conditioned orienting predicts preference for, and affective response to, amphetamine after multiple exposures in male ratsPreprint

Hilz, E. N., Morales-Grahl, E., Patel, A., Knight, T., Monfils, M., & Lee, H. J. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.06.674656 · Cited by 1 · see citing works

DEVELOPMENT OF AN AVIAN MODEL FOR IDENTIFYING INDIVIDUAL DIFFERENCES IN DRUG VULNERABILITY

Rice, B. A. (2015) · UKnowledge (University of Kentucky)

Contributions of individual differences in stress reactivity to post-traumatic stress disorder vulnerability and resilience

Hill, J. E. (2013)

Imprinted genes, impulsivity and risk-taking

Dent, C. L. (2014) · ORCA Online Research @Cardiff (Cardiff University)

Individual Variation in the Motivational Properties of Reward Cues.

Saunders, B. T. (2013) · Deep Blue (University of Michigan)

EXAMINING MEMORY CONSOLIDATION AND RECONSOLIDATION IN AN APPETITIVE PAVLOVIAN TASK

Chow, J. J. (2015) · UKnowledge (University of Kentucky) · doi:10.13023/etd.2016.004

Individual Variation in the Extent to Which Drug Cues Acquire Control Over Motivated Behavior.

Yager, L. M. (2014) · Deep Blue (University of Michigan)

Assessing individual differences: novelty and ultrasonic vocalizations predict acute and chronic D-amphetamine response in rats

Garcia, E. J. (2014) · K-State Research Exchange (Kansas State University)

Incentive salience attribution, “sensation-seeking” and “novelty-seeking” are independent traits in a large sample of male and female heterogeneous stock ratsPreprint

Netzley, A. H., Horvath, A. P., Holl, K., Palmer, A. A., Woods, L. C. S., Robinson, T. E., & Flagel, S. B. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/421065 · Cited by 1 · see citing works

A Cocaine Cue Acts as an Incentive Stimulus in Some but not Others: Implications for Addiction

Saunders, B. T., & Robinson, T. E. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.11.015 · Cited by 271 · see citing works

Individual differences in the attribution of incentive salience to reward-related cues: implications for addiction

Flagel, S. B., Akil, H., & Robinson, T. E. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.06.027 · Cited by 561 · see citing works

Incentive salience, not psychomotor sensitization or tolerance, drives escalation of cocaine self-administration in heterogeneous stock rats

Ramborger, J., Mosquera, J., Brennan, M., Sichel, B. C., Othman, D. N., Plasil, S. L., Sneddon, E. A., Bonnet-Zahedi, S., Morgan, A., Chonwattanagul, S., et al. (2026) · Neuropsychopharmacology · doi:10.1038/s41386-026-02350-0 · Cited by 4 · see citing works

A classically conditioned cocaine cue acquires greater control over motivated behavior in rats prone to attribute incentive salience to a food cue

Yager, L. M., & Robinson, T. E. (2013) · Psychopharmacology · doi:10.1007/s00213-012-2890-y · Cited by 123 · see citing works