Alcohol alters hepatic FoxO1, p53, and mitochondrial SIRT5 deacetylation function

Surfing the p53 network

Vogelstein, B., Lane, D., & Levine, A. J. (2000) · Nature · doi:10.1038/35042675 · Cited by 6,607 · see citing works

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y., et al. (2004) · Science · doi:10.1126/science.1094637 · Cited by 3,239 · see citing works

p53 Regulates Mitochondrial Respiration

Matoba, S., Kang, J.-G., Patino, W. D., Wragg, A., Boehm, M., Gavrilova, O., Hurley, P. J., Bunz, F., & Hwang, P. M. (2006) · Science · doi:10.1126/science.1126863 · Cited by 1,650 · see citing works

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

Michishita, E., Park, J. Y., Burneskis, J. M., Barrett, J. C., & Horikawa, I. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-01-0033 · Cited by 1,364 · see citing works

Mammalian sirtuins—emerging roles in physiology, aging, and calorie restriction

Haigis, M. C., & Guarente, L. P. (2006) · Genes & Development · doi:10.1101/gad.1467506 · Cited by 1,295 · see citing works

NAD+ metabolism in health and disease

Belenky, P. A., Bogan, K. L., & Brenner, C. (2006) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2006.11.006 · Cited by 983 · see citing works

Cytochrome P-4502E1: its physiological and pathological role

Lieber, C. S. (1997) · Physiological Reviews · doi:10.1152/physrev.1997.77.2.517 · Cited by 889 · see citing works

Mitochondrial Signaling

Butow, R. A., & Avadhani, N. G. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00179-0 · Cited by 882 · see citing works

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

Schwer, B., Bunkenborg, J., Verdin, R. O., Andersen, J. S., & Verdin, E. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603968103 · Cited by 705 · see citing works

Inhibition of SIRT1 Catalytic Activity Increases p53 Acetylation but Does Not Alter Cell Survival following DNA Damage

Solomon, J. M., Pasupuleti, R., Xu, L., McDonagh, T., Curtis, R., DiStefano, P. S., & Huber, L. J. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.26.1.28-38.2006 · Cited by 481 · see citing works

Sirtuin Functions in Health and Disease

Yamamoto, H., Schoonjans, K., & Auwerx, J. (2007) · Molecular Endocrinology · doi:10.1210/me.2007-0079 · Cited by 480 · see citing works

Metabolism of Alcohol

Lieber, C. S. (2005) · Clinics in Liver Disease · doi:10.1016/j.cld.2004.10.005 · Cited by 274 · see citing works

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

Rena, G., Prescott, A. R., Guo, S., Cohen, P., & Unterman, T. G. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3540605 · Cited by 261 · see citing works

Involvement of mammalian sirtuin 1 in the action of ethanol in the liver

You, M., Liang, X., Ajmo, J. M., & Ness, G. C. (2008) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00575.2007 · Cited by 214 · see citing works

FOXO transcription factors: key regulators of cell fate

Lam, E. W. ‐., Francis, R. E., & Petković, M. (2006) · Biochemical Society Transactions · doi:10.1042/bst0340722 · Cited by 214 · see citing works

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

Rena, G., Prescott, A. R., Shaodong, G. U. O., et al. (2001) · Biochemical Journal · doi:10.1042/bj3540605 · Cited by 199 · see citing works

[58] Animal models of chronic ethanol toxicity

LIEBER, C. S., & DeCarli, L. M. (1994) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(94)33061-1 · Cited by 196 · see citing works

Elevated Mitochondrial Cytochrome P450 2E1 and Glutathione S-Transferase A4-4 in Streptozotocin-Induced Diabetic Rats

Raza, H., Prabu, S. K., Robin, M.-A., & Avadhani, N. G. (2004) · Diabetes · doi:10.2337/diabetes.53.1.185 · Cited by 186 · see citing works

The expression of SIRT1 in nonalcoholic fatty liver disease induced by high‐fat diet in rats

Deng, X., Chen, L., & Li, N. (2007) · Liver International · doi:10.1111/j.1478-3231.2007.01497.x · Cited by 174 · see citing works

NAD metabolism and sirtuins: Metabolic regulation of protein deacetylation in stress and toxicity

Yang, T., & Sauve, A. A. (2006) · The AAPS Journal · doi:10.1208/aapsj080472 · Cited by 170 · see citing works

The Forkhead Transcription Factor FoxO1 Regulates Proliferation and Transdifferentiation of Hepatic Stellate Cells

Adachi, M., Osawa, Y., Uchinami, H., Kitamura, T., Accili, D., & Brenner, D. A. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.01.033 · Cited by 155 · see citing works

Effect of chronic alcohol consumption on Hepatic SIRT1 and PGC-1α in rats

Lieber, C. S., Leo, M. A., Wang, X., & DeCarli, L. M. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.03.005 · Cited by 135 · see citing works

In Defense of “Dependence”

Erickson, C. K. (2007) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2007.00521.x · Cited by 104 · see citing works

Energy sensing and regulation of gene expression in skeletal muscle

Freyssenet, D. G. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01126.2005 · Cited by 83 · see citing works

Gene Expression Profiling of Alcoholic Liver Disease in the Baboon (Papio hamadryas) and Human Liver

Seth, D., Leo, M. A., McGuinness, P. H., Lieber, C. S., Brennan, Y., Williams, R. B. H., Wang, X. M., McCaughan, G. W., Gorrell, M. D., & Haber, P. (2003) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63587-0 · Cited by 78 · see citing works

Acute ethanol exposure inhibits insulin signaling in the liver

He, J., de la Monte, S. M., & Wands, J. R. (2007) · Hepatology · doi:10.1002/hep.21904 · Cited by 71 · see citing works

Adipose Differentiation‐Related Protein Is a Reliable Lipid Droplet Marker in Alcoholic Fatty Liver of Rats

Mak, K. M., Ren, C., Ponomarenko, A. N., Cao, Q., & Lieber, C. S. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00624.x · Cited by 60 · see citing works

Alcohol intoxication impairs phosphorylation of S6K1 and S6 in skeletal muscle independently of ethanol metabolism.

Lang, C. H., Pruznak, A., Deshpande, N., Palopoli, M., Frost, R., & Vary, T. (2004) · Alcoholism: Clinical and Experimental Research · doi:10.1097/01.alc.0000145787.66405.59 · Cited by 56 · see citing works

Role of Medium‐Chain Triglycerides in the Alcohol‐Mediated Cytochrome P450 2E1 Induction of Mitochondria

Lieber, C. S., Cao, Q., DeCarli, L. M., Leo, M. A., Mak, K. M., Ponomarenko, A. N., Ren, C., & Wang, X. (2007) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2007.00475.x · Cited by 46 · see citing works

Acetylation in Nuclear Receptor Signaling and the Role of Sirtuins

Wang, C., Powell, M. J., Popov, V. M., & Pestell, R. G. (2007) · Molecular Endocrinology · doi:10.1210/me.2007-0379 · Cited by 39 · see citing works

Ethanol feeding enhances age-related deterioration of the rat hepatic mitochondrion

Cahill, A., Hershman, S. H., Davies, A. M., & Sýkora, P. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00193.2005 · Cited by 30 · see citing works

Nicotinamide Counteracts Alcohol-Induced Impairment of Hepatic Protein Metabolism in Humans ,

Volpi, E., Lucidi, P., Cruciani, G., Monacchia, F., Reboldi, G., Brunetti, P., Bolli, G. B., & Feo, P. D. (1997) · Journal of Nutrition · doi:10.1093/jn/127.11.2199 · Cited by 23 · see citing works

Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury

Rungratanawanich, W., Qu, Y., Wang, X., Essa, M. M., & Song, B.-J. (2021) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00561-7 · Cited by 411 · see citing works

Resveratrol alleviates alcoholic fatty liver in mice

Ajmo, J. M., Liang, X., Rogers, C. Q., Pennock, B., & You, M. (2008) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.90358.2008 · Cited by 370 · see citing works

Control of metabolism by p53 – Cancer and beyond

Labuschagne, C. F., Zani, F., & Vousden, K. H. (2018) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2018.06.001 · Cited by 219 · see citing works

Contributing roles of mitochondrial dysfunction and hepatocyte apoptosis in liver diseases through oxidative stress, post-translational modifications, inflammation, and intestinal barrier dysfunction

LeFort, K. R., Rungratanawanich, W., & Song, B.-J. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-05061-7 · Cited by 202 · see citing works

Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease

Derdák, Z., Villegas, K. A., Harb, R., Wu, A. M., Sousa, A., & Wands, J. R. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.11.042 · Cited by 193 · see citing works

Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-α production in cultured macrophage cell lines

Shen, Z., Ajmo, J. M., Rogers, C. Q., Liang, X., Le, L., Murr, M. M., Peng, Y., & You, M. (2009) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00016.2009 · Cited by 172 · see citing works

PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis

Mukhopadhyay, P., Horváth, B., Rajesh, M., Varga, Z. V., Gariani, K., Ryu, D., Cao, Z., Holovac, E., Park, O., Zhou, Z., et al. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2016.10.023 · Cited by 168 · see citing works

Adiponectin and alcoholic fatty liver disease

Rogers, C. Q., Ajmo, J. M., & You, M. (2008) · IUBMB Life · doi:10.1002/iub.124 · Cited by 138 · see citing works

Epigenetic Regulation of miR-34a Expression in Alcoholic Liver Injury

Meng, F., Glaser, S. S., Francis, H., Yang, F., Han, Y., Stokes, A., Staloch, D. A., McCarra, J., Liu, J., Venter, J. K., et al. (2012) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.06.010 · Cited by 140 · see citing works

Direct evidence of sirtuin downregulation in the liver of non-alcoholic fatty liver disease patients.

Wu, T., Liu, Y., Fu, Y., Liu, X., & Zhou, X.-H. (2014) · PubMed · Cited by 135 · see citing works

Sirtuin 1 signaling and alcoholic fatty liver disease.

You, M., Jogasuria, A. P., Taylor, C., & Wu, J. (2015) · PubMed Central · doi:10.3978/j.issn.2304-3881.2014.12.06 · Cited by 132 · see citing works

Mitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modifications

Song, B.-J., Akbar, M., Abdelmegeed, M. A., Byun, K., Lee, B., Yoon, S. K., & Hardwick, J. P. (2014) · Redox Biology · doi:10.1016/j.redox.2014.10.004 · Cited by 123 · see citing works

Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice

Fritz, K. S., Galligan, J. J., Hirschey, M. D., Verdin, E., & Petersen, D. R. (2012) · Journal of Proteome Research · doi:10.1021/pr2008384 · Cited by 121 · see citing works

Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease

Derdák, Z., Lang, C. H., Villegas, K. A., Tong, M., Mark, N. M., de la Monte, S. M., & Wands, J. R. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.08.007 · Cited by 114 · see citing works

Adiponectin: A Key Adipokine in Alcoholic Fatty Liver

You, M., & Rogers, C. Q. (2009) · Experimental Biology and Medicine · doi:10.3181/0902-mr-61 · Cited by 113 · see citing works

Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates

Yao, Y.-L., & Yang, W.-M. (2010) · Journal of Biomedicine and Biotechnology · doi:10.1155/2011/146493 · Cited by 120 · see citing works

NAD+-dependent histone deacetylases (sirtuins) as novel therapeutic targets

Schemies, J., Uciechowska, U., Sippl, W., & Jung, M. (2009) · Medicinal Research Reviews · doi:10.1002/med.20178 · Cited by 91 · see citing works

Who watches the watchmen? Regulation of the expression and activity of sirtuins

Buler, M., Andersson, U., & Hakkola, J. (2016) · The FASEB Journal · doi:10.1096/fj.201600410rr · Cited by 84 · see citing works

Alcohol-induced protein hyperacetylation: Mechanisms and consequences

Shepard, B. D. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.1219 · Cited by 83 · see citing works

Chapter 5 Sirtuins and p53

van Leeuwen, I., & Laı́n, S. (2009) · Advances in cancer research · doi:10.1016/s0065-230x(09)02005-3 · Cited by 79 · see citing works

Inhibitors to understand molecular mechanisms of NAD+-dependent deacetylases (sirtuins)

Lawson, M. K., Uciechowska, U., Schemies, J., Rumpf, T., Jung, M., & Sippl, W. (2010) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2010.06.003 · Cited by 76 · see citing works

Function and regulation of the mitochondrial Sirtuin isoform Sirt5 in Mammalia

Gertz, M., & Steegborn, C. (2009) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2009.09.011 · Cited by 75 · see citing works

Post-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications

Song, B.-J., Abdelmegeed, M. A., Yoo, S.-H., Kim, B.-J., Jo, S. A., Jo, I., & Moon, K.-H. (2011) · Journal of Proteomics · doi:10.1016/j.jprot.2011.05.013 · Cited by 73 · see citing works

Targeting oxidative stress in cancer

Lawless, M. W., O'Byrne, K. J., & Gray, S. G. (2010) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2010.526933 · Cited by 72 · see citing works

Using mitochondrial sirtuins as drug targets: disease implications and available compounds

Gertz, M., & Steegborn, C. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2180-7 · Cited by 71 · see citing works

Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats

Li, M., Lü, Y., Hu, Y. W., Zhai, X., Xu, W. L., Jing, H., Tian, X., Lin, Y., Gao, D., & Yao, J. (2014) · Toxicology Letters · doi:10.1016/j.toxlet.2014.04.011 · Cited by 70 · see citing works

Ethanol intoxication increases hepatic N-lysyl protein acetylation

Picklo, M. J. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.09.039 · Cited by 60 · see citing works

Insulin resistance in clinical and experimental alcoholic liver disease

Carr, R. M., & Correnti, J. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12787 · Cited by 56 · see citing works

Roles of sirtuins in the regulation of antioxidant defense and bioenergetic function of mitochondria under oxidative stress

Wu, Y., Wu, S., & Wei, Y. (2014) · Free Radical Research · doi:10.3109/10715762.2014.920956 · Cited by 56 · see citing works

Mitochondrial sirtuins and metabolic homeostasis

Pirinen, E., Sasso, G. L., & Auwerx, J. H. (2012) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2012.05.001 · Cited by 56 · see citing works

A Unifying Hypothesis Linking Hepatic Adaptations for Ethanol Metabolism to the Proinflammatory and Profibrotic Events of Alcoholic Liver Disease

Zhong, Z., & Lemasters, J. J. (2018) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13877 · Cited by 55 · see citing works

Ethanol Metabolism Modifies Hepatic Protein Acylation in Mice

Fritz, K. S., Green, M. F., Petersen, D. R., & Hirschey, M. D. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075868 · Cited by 53 · see citing works

Translational Implications of the Alcohol-Metabolizing Enzymes, Including Cytochrome P450-2E1, in Alcoholic and Nonalcoholic Liver Disease

Song, B., Akbar, M. D., Jo, I., Hardwick, J. P., & Abdelmegeed, M. A. (2015) · Advances in pharmacology · doi:10.1016/bs.apha.2015.04.002 · Cited by 49 · see citing works

Hepatic p63 regulates steatosis via IKKβ/ER stress

Porteiro, B., Fondevila, M. F., Delgado, T. C., Iglesias, C., Imbernón, M., Iruzubieta, P., Crespo, J., Zabala‐Letona, A., Fernø, J., González‐Terán, B., et al. (2017) · Nature Communications · doi:10.1038/ncomms15111 · Cited by 47 · see citing works

The Adiponectin-SIRT1-AMPK Pathway in Alcoholic Fatty Liver Disease in the Rat

Jiang, Z., Zhou, J., Zhou, D., Zhu, Z., Sun, L., & Nanji, A. A. (2015) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12641 · Cited by 47 · see citing works

Rutin Attenuates Hepatotoxicity in High‐Cholesterol‐Diet‐Fed Rats

AlSharari, S. D., Al-Rejaie, S. S., Abuohashish, H. M., Ahmed, M. M. M., & Hafez, M. M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/5436745 · Cited by 46 · see citing works

Regulation and protection of mitochondrial physiology by sirtuins

Pereira, C. V., Lebiedzińska, M., Wieckowski, M. R., & Oliveira, P. J. (2011) · Mitochondrion · doi:10.1016/j.mito.2011.07.003 · Cited by 45 · see citing works

Vitexin protects against ethanol-induced liver injury through Sirt1/p53 signaling pathway

Yuan, H., Duan, S., Guan, T., Yuan, X., Lin, J., Hou, S., Lai, X., Huang, S. M., Du, X., & Chen, S. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173007 · Cited by 45 · see citing works

Methyl ferulic acid attenuates ethanol-induced hepatic steatosis by regulating AMPK and FoxO1 Pathways in Rats and L-02 cells

Cheng, Q., Li, Y., Yang, C., Zhong, Y., He, H., Zhu, F.-C., & Li, L. (2018) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2018.06.028 · Cited by 40 · see citing works

Peroxisome Proliferator‐Activated Receptor and Retinoic X Receptor in Alcoholic Liver Disease

Mello, T., Polvani, S., & Galli, A. (2009) · PPAR Research · doi:10.1155/2009/748174 · Cited by 38 · see citing works

Understanding the Tumor Suppressor PTEN in Chronic Alcoholism and Hepatocellular Carcinoma

Shearn, C. T., & Petersen, D. R. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-09614-8_10 · Cited by 35 · see citing works

Aberrant post-translational protein modifications in the pathogenesis of alcohol-induced liver injury

Osna, N. A., Carter, W. G., Ganesan, M., Kirpich, I., McClain, C. J., Petersen, D. R., Shearn, C. T., Tomasi, M. L., & Kharbanda, K. K. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i27.6192 · Cited by 28 · see citing works

NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice

Xiong, X., Yu, J., Fan, R., Zhang, C., Xu, L., Sun, X., Huang, Y., Wang, Q., Ruan, H., & Qian, X. (2019) · PLoS ONE · doi:10.1371/journal.pone.0212523 · Cited by 28 · see citing works

In Vivo Metabolic Tracing Demonstrates the Site‐Specific Contribution of Hepatic Ethanol Metabolism to Histone Acetylation

Kriss, C. L., Gregory‐Lott, E., Storey, A. J., Tackett, A. J., Wahls, W. P., & Stevens, S. M. (2018) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13843 · Cited by 25 · see citing works

Meta-analysis reveals up-regulation of cholesterol processes in non-alcoholic and down-regulation in alcoholic fatty liver disease

Wruck, W., & Adjaye, J. (2017) · World Journal of Hepatology · doi:10.4254/wjh.v9.i8.443 · Cited by 24 · see citing works

p53 in liver pathologies—taking the good with the bad

Charni‐Natan, M., Rivlin, N., Molchadsky, A., Aloni-Grinstein, R., & Rotter, V. (2014) · Journal of Molecular Medicine · doi:10.1007/s00109-014-1223-5 · Cited by 24 · see citing works

Insights of mitochondrial involvement in alcoholic fatty liver disease

Nithyananthan, S. (2023) · Journal of Cellular Physiology · doi:10.1002/jcp.31100 · Cited by 22 · see citing works

Allium victorialis L. Extracts Promote Activity of FXR to Ameliorate Alcoholic Liver Disease: Targeting Liver Lipid Deposition and Inflammation

Cui, Z., Han, X., Jiang, Y.-C., Dou, J.-Y., Yao, K.-C., Hu, Z.-H., Yuan, M.-H., Bao, X.-X., Zhou, M.-J., Liu, Y., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.738689 · Cited by 20 · see citing works

Post-translational modifications of histone and non-histone proteins in epigenetic regulation and translational applications in alcohol-associated liver disease: Challenges and research opportunities

Rungratanawanich, W., Ballway, J. W., Wang, X., Won, K., Hardwick, J. P., & Song, B. (2023) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2023.108547 · Cited by 22 · see citing works

Role of SIRT5 in cancer. Friend or Foe?

Lagunas‐Rangel, F. A. (2023) · Biochimie · doi:10.1016/j.biochi.2023.02.008 · Cited by 19 · see citing works

Identification of key genes, MicroRNAs and potentially regulated pathways in alcoholic hepatitis by integrative analysis

Yao, J., Cheng, Y., Zhang, D., Fan, J., Zhao, Z., Li, Y., Jiang, Y., & Guo, Y. (2019) · Gene · doi:10.1016/j.gene.2019.144035 · Cited by 19 · see citing works

Sphingolipids and the link between alcohol and cancer

Barron, K. A., Jeffries, K. A., & Krupenko, N. I. (2020) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2020.109058 · Cited by 19 · see citing works

Biochemical Mechanisms of Sirtuin-Directed Protein Acylation in Hepatic Pathologies of Mitochondrial Dysfunction

McGinnis, C. D., Jennings, E. Q., Harris, P. S., Galligan, J. J., & Fritz, K. S. (2022) · Cells · doi:10.3390/cells11132045 · Cited by 18 · see citing works

Actions of Alcohol in Brain: Genetics, Metabolomics, GABA Receptors, Proteomics and Glutamate Transporter GLAST/EAAT1

Kashem, M. A., Šerý, O., Pow, D. V., Rowlands, B. D., Rae, C. D., & Balcar, V. J. (2020) · Current Molecular Pharmacology · doi:10.2174/1874467213666200424155244 · Cited by 17 · see citing works

The role of SIRT5 and p53 proteins in the sensitivity of colon cancer cells to chemotherapeutic agent 5-Fluorouracil

Ekremoglu, O., & Koç, A. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06558-9 · Cited by 17 · see citing works

The p53 Codon 72 Polymorphism Modifies the Cellular Response to Inflammatory Challenge in the Liver

Leu, J. I.-J., Murphy, M. E., & George, D. L. (2013) · Journal of Liver · doi:10.4172/2167-0889.1000117 · Cited by 15 · see citing works

Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder

Moreno, M. C., Mooney, S. M., & Middleton, F. A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180873 · Cited by 13 · see citing works

Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis

Fonseca, T. L., Fernandes, G. W., Bocco, B. M. L. C., Keshavarzian, A., Jakate, S. M., Donohue, T. M., Gereben, B., & Bianco, A. C. (2019) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14027 · Cited by 13 · see citing works

Role of p53 family in birth defects: Lessons from zebrafish

Danilova, N., Sakamoto, K. M., & Lin, S. (2008) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.20129 · Cited by 13 · see citing works

Cytochrome P450 2E1‐dependent hepatic ethanol metabolism induces fatty acid‐binding protein 4 and steatosis

Attal, N., Marrero, E., Thompson, K. J., & McKillop, I. H. (2022) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14828 · Cited by 12 · see citing works

Caffeic acid dimethyl ether alleviates alcohol-induced hepatic steatosis via microRNA-378b-mediated CaMKK2-AMPK pathway

Lu, J., Zhang, Y., Wang, Y., Li, Y., Wang, R., Zhong, Y.-J., Chen, L., Song, M.-W., Li, L., Li, Y., et al. (2022) · Bioengineered · doi:10.1080/21655979.2022.2060586 · Cited by 11 · see citing works

Alcoholic and Non-Alcoholic Liver Diseases: Promising Molecular Drug Targets and their Clinical Development

Thapa, K., Grewal, A. S., Kanojia, N., Rani, L., Sharma, N., & Singh, S. (2020) · Current Drug Discovery Technologies · doi:10.2174/1570163817666200121143959 · Cited by 12 · see citing works

Elevated expression of forkhead box protein O1 (FoxO1) in alcohol-induced intestinal barrier dysfunction

Wang, Y., Tong, J., Zou, D., Chang, B., Wang, B., & Wang, B. (2013) · Acta Histochemica · doi:10.1016/j.acthis.2012.12.005 · Cited by 8 · see citing works

Alcohol exposure suppresses ribosome biogenesis and causes nucleolar stress in cranial neural crest cells

Flentke, G. R., Wilkie, T. E., Baulch, J. W., Huang, Y., & Smith, S. M. (2024) · PLoS ONE · doi:10.1371/journal.pone.0304557 · Cited by 7 · see citing works

Cloning, chromosomal characterization and FISH mapping of the NAD+-dependent histone deacetylase gene sirtuin 5 in the mouse

Voelter‐Mahlknecht, S., & Mahlknecht, U. (2013) · International Journal of Oncology · doi:10.3892/ijo.2013.1939 · Cited by 5 · see citing works

Plasma metabolic profiles in alcohol use disorder: diagnostic role of arginine and emotional implications of N6-acetyl-lysine and succinic acid

Cao, G., Chen, B., Sun, Y., Qiao, J., Liu, T., Hou, J., Han, X., Tang, Y., Fu, Y., Ye, J., et al. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-07014-9 · Cited by 4 · see citing works

Prospect of Mitochondria-Targeted Antioxidants as a Hepatoprotective and Anti-Alcoholic Liver Disease AgentPreprint

Abugri, J., & Adu‐Frimpong, M. (2021) · Preprints.org · doi:10.20944/preprints202103.0143.v1 · Cited by 2 · see citing works

Current World Literature

(2009) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e32832cef8f · Cited by 1 · see citing works

Sirtuins as Potential Drug Targets for Metabolic Diseases

Tong, Q. (2011) · doi:10.1002/9780470910016.ch15

Role of iron in ethanol derived hepatic stress

Thornton, J. A. (2013)

Mechanisms of Hepatic Steatosis

Nagy, L. E. (2010) · Elsevier eBooks · doi:10.1016/b978-0-08-046884-6.01010-1

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Lieber, C. S., Leo, M. A., Wang, X., & DeCarli, L. M. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.03.005 · Cited by 135 · see citing works

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Yin, H., Hu, M., Liang, X., Ajmo, J. M., Li, X., Bataller, R. A., Òdena, G., Stevens, S. M., & You, M. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.11.008 · Cited by 211 · see citing works

Involvement of mitochondrial protein post translational modification in the pathogenesis of alcoholic liver disease

Assiri, M. (2019) · doi:10.25677/mmxf-2t82

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do Nascimento, A. F., Ip, B. C., Luvizotto, R. A. M., Seitz, H. K., & Wang, X. (2013) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2304-3881.2013.07.05 · Cited by 24 · see citing works

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Moon, K.-H., Hood, B. L., Kim, B.-J., Hardwick, J. P., Conrads, T. P., Veenstra, T. D., & Song, B. J. (2006) · Hepatology · doi:10.1002/hep.21372 · Cited by 120 · see citing works