Biofabrication of bone tissue: approaches, challenges and translation for bone regeneration

3D bioprinting of tissues and organs

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Porosity of 3D biomaterial scaffolds and osteogenesis

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Mesenchymal stem cells

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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering

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Biomaterials & scaffolds for tissue engineering

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On the mechanisms of biocompatibility

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Bone Tissue Engineering: Recent Advances and Challenges

Amini, A. R., Laurencin, C. T., & Nukavarapu, S. P. (2012) · Critical Reviews in Biomedical Engineering · doi:10.1615/critrevbiomedeng.v40.i5.10 · Cited by 2,342 · see citing works

Recent advances in bone tissue engineering scaffolds

Bose, S., Roy, M., & Bandyopadhyay, A. K. (2012) · Trends in biotechnology · doi:10.1016/j.tibtech.2012.07.005 · Cited by 2,217 · see citing works

3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs

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WNT signaling in bone homeostasis and disease: From human mutations to treatments

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Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

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25th Anniversary Article: Engineering Hydrogels for Biofabrication

Malda, J., Visser, J., Melchels, F. P., Jüngst, T., Hennink, W. E., Dhert, W. J. A., Groll, J., & Hutmacher, D. W. (2013) · Advanced Materials · doi:10.1002/adma.201302042 · Cited by 1,901 · see citing works

Bone tissue engineering using 3D printing

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25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine

Annabi, N., Tamayol, A., Uquillas, J. A., Akbari, M., Bertassoni, L. E., Cha, C., Camci‐Unal, G., Dokmeci, M. R., Peppas, N. A., & Khademhosseini, A. (2014) · Advanced Materials · doi:10.1002/adma.201303233 · Cited by 1,409 · see citing works

A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering

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Bone regenerative medicine: classic options, novel strategies, and future directions

Oryan, A., Alidadi, S., Moshiri, A., & Maffulli, N. (2014) · Journal of Orthopaedic Surgery and Research · doi:10.1186/1749-799x-9-18 · Cited by 1,249 · see citing works

Additive manufacturing of tissues and organs

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Stem cell fate dictated solely by altered nanotube dimension

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Printing and Prototyping of Tissues and Scaffolds

Derby, B. (2012) · Science · doi:10.1126/science.1226340 · Cited by 1,108 · see citing works

Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate

Dalby, M. J., Gadegaard, N., & Oreffo, R. O. C. (2014) · Nature Materials · doi:10.1038/nmat3980 · Cited by 1,082 · see citing works

Fibrin: A versatile scaffold for tissue engineering applications

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Osteogenesis and angiogenesis: The potential for engineering bone

Kanczler, J. M., & Oreffo, R. (2008) · European Cells and Materials · doi:10.22203/ecm.v015a08 · Cited by 984 · see citing works

ENGINEERING PRINCIPLES OF CLINICAL CELL-BASED TISSUE ENGINEERING

Muschler, G. F., Nakamoto, C., & Griffith, L. G. (2004) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-200407000-00029 · Cited by 878 · see citing works

Laser assisted bioprinting of engineered tissue with high cell density and microscale organization

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A review of rapid prototyping techniques for tissue engineering purposes

Turunen, S., Melchels, F. P. W., Grijpma, D. W., & Kellomäki, M. (2008) · Annals of Medicine · doi:10.1080/07853890701881788 · Cited by 752 · see citing works

Reinforcement of hydrogels using three-dimensionally printed microfibres

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In vitro and in vivo characteristics of PCL scaffolds with pore size gradient fabricated by a centrifugation method

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Human microvasculature fabrication using thermal inkjet printing technology

Cui, X., & Boland, T. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.07.056 · Cited by 706 · see citing works

Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies

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Characterization of cell viability during bioprinting processes

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Creating perfused functional vascular channels using 3D bio-printing technology

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The chicken chorioallantoic membrane model in biology, medicine and bioengineering

Nowak-Sliwinska, P. M., Segura, T., & Iruela‐Arispe, M. L. (2014) · Angiogenesis · doi:10.1007/s10456-014-9440-7 · Cited by 481 · see citing works

Hydrogels as Extracellular Matrices for Skeletal Tissue Engineering: State-of-the-Art and Novel Application in Organ Printing

Fedorovich, N. E., Alblas, J., de Wijn, J. R., Hennink, W. E., Verbout, A. J., & Dhert, W. J. A. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0175 · Cited by 467 · see citing works

Bone grafting, orthopaedic biomaterials, and the clinical need for bone engineering

Brydone, A. S., Meek, D. R. M., & Maclaine, S. E. (2010) · Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine · doi:10.1243/09544119jeim770 · Cited by 456 · see citing works

Vascularization in Bone Tissue Engineering: Physiology, Current Strategies, Major Hurdles and Future Challenges

Santos, M. I., & Reis, R. L. (2009) · Macromolecular Bioscience · doi:10.1002/mabi.200900107 · Cited by 445 · see citing works

Cell patterning technologies for organotypic tissue fabrication

Guillotin, B., & Guillemot, F. (2011) · Trends in biotechnology · doi:10.1016/j.tibtech.2010.12.008 · Cited by 430 · see citing works

Bioprinting for stem cell research

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Three-Dimensional Fiber Deposition of Cell-Laden, Viable, Patterned Constructs for Bone Tissue Printing

Fedorovich, N. E., de Wijn, J. R., Verbout, A. J., Alblas, J., & Dhert, W. J. A. (2008) · Tissue Engineering Part A · doi:10.1089/ten.a.2007.0158 · Cited by 415 · see citing works

Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells

Simmons, C. A., Alsberg, E., Hsiong, S. X., Kim, W. J., & Mooney, D. J. (2004) · Bone · doi:10.1016/j.bone.2004.02.027 · Cited by 414 · see citing works

Bioprinting of hybrid tissue constructs with tailorable mechanical properties

Schuurman, W., Khristov, V., Pot, M. W., van Weeren, P. R., Dhert, W. J. A., & Malda, J. (2011) · Biofabrication · doi:10.1088/1758-5082/3/2/021001 · Cited by 411 · see citing works

Biofabrication of Osteochondral Tissue Equivalents by Printing Topologically Defined, Cell-Laden Hydrogel Scaffolds

Fedorovich, N. E., Schuurman, W., Wijnberg, H. M., Prins, H., van Weeren, P. R., Malda, J., Alblas, J., & Dhert, W. J. A. (2011) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2011.0060 · Cited by 402 · see citing works

Bioprinting of a mechanically enhanced three-dimensional dual cell-laden construct for osteochondral tissue engineering using a multi-head tissue/organ building system

Shim, J., Lee, J., Kim, J. Y., & Cho, D. (2012) · Journal of Micromechanics and Microengineering · doi:10.1088/0960-1317/22/8/085014 · Cited by 382 · see citing works

Biofabrication: a 21st century manufacturing paradigm

Mironov, V. A., Trusk, T. C., Kasyanov, V. A., Little, S., Swaja, R., & Markwald, R. R. (2009) · Biofabrication · doi:10.1088/1758-5082/1/2/022001 · Cited by 369 · see citing works

Microenvironments Engineered by Inkjet Bioprinting Spatially Direct Adult Stem Cells Toward Muscle- and Bone-Like Subpopulations

Phillippi, J. A., Miller, E. D., Weiss, L. E., Huard, J., Waggoner, A. S., & Campbell, P. G. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0520 · Cited by 361 · see citing works

Bioactive nanoparticles stimulate bone tissue formation in bioprinted three‐dimensional scaffold and human mesenchymal stem cells

Gao, G., Schilling, A. F., Yonezawa, T., Wang, J., Dai, G., & Cui, X. (2014) · Biotechnology Journal · doi:10.1002/biot.201400305 · Cited by 352 · see citing works

Laser-based direct-write techniques for cell printing

Schiele, N. R., Corr, D. T., Huang, Y. H., Raof, N. A., Xie, Y., & Chrisey, D. B. (2010) · Biofabrication · doi:10.1088/1758-5082/2/3/032001 · Cited by 335 · see citing works

A review of materials, fabrication methods, and strategies used to enhance bone regeneration in engineered bone tissues

Stevens, B., Yang, Y., Mohandas, A., Stucker, B. E., & Nguyen, K. T. (2007) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.30962 · Cited by 326 · see citing works

Vascularized Bone Tissue Engineering: Approaches for Potential Improvement

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Scaffolds with covalently immobilized VEGF and Angiopoietin-1 for vascularization of engineered tissues

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Evaluating 3D‐Printed Biomaterials as Scaffolds for Vascularized Bone Tissue Engineering

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Laser Printing of Stem Cells for Biofabrication of Scaffold-Free Autologous Grafts

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Vascularization in Bone Tissue Engineering Constructs

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The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells

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Engineering biomaterials to integrate and heal: The biocompatibility paradigm shifts

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Development of a hybrid scaffold with synthetic biomaterials and hydrogel using solid freeform fabrication technology

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Additively manufactured 3D porous Ti-6Al-4V constructs mimic trabecular bone structure and regulate osteoblast proliferation, differentiation and local factor production in a porosity and surface roughness dependent manner

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Photo-patterning of porous hydrogels for tissue engineering

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Concepts of scaffold‐based tissue engineering—the rationale to use solid free‐form fabrication techniques

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Dose Effect of Dual Delivery of Vascular Endothelial Growth Factor and Bone Morphogenetic Protein-2 on Bone Regeneration in a Rat Critical-Size Defect Model

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Anabolic Effects of 1,25-Dihydroxyvitamin D3 on Osteoblasts Are Enhanced by Vascular Endothelial Growth Factor Produced by Osteoblasts and by Growth Factors Produced by Endothelial Cells*

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There is no such thing as a biocompatible material

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Laser-assisted bioprinting for creating on-demand patterns of human osteoprogenitor cells and nano-hydroxyapatite

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Impact of pore size on the vascularization and osseointegration of ceramic bone substitutes in vivo

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Biofabrication: an overview of the approaches used for printing of living cells

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Laser Printing of Single Cells: Statistical Analysis, Cell Viability, and Stress

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Stem cells in bone tissue engineering

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Tunable dual growth factor delivery from polyelectrolyte multilayer films

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Mesenchymal Stem Cells: Lineage, Plasticity, and Skeletal Therapeutic Potential

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Bone tissue engineering with human stem cells

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Organ printing: the future of bone regeneration?

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Engineering bone tissue substitutes from human induced pluripotent stem cells

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Three-Dimensional Printing of Nanomaterial Scaffolds for Complex Tissue Regeneration

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Methods for Photocrosslinking Alginate Hydrogel Scaffolds with High Cell Viability

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Effect of Grafting RGD and BMP-2 Protein-Derived Peptides to a Hydrogel Substrate on Osteogenic Differentiation of Marrow Stromal Cells

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Tissue engineered bone using select growth factors: A comprehensive review of animal studies and clinical translation studies in man

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The Correlation Between the Internal Structure and Vascularization of Controllable Porous Bioceramic Materials In Vivo : A Quantitative Study

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Influence of β-tricalcium phosphate granule size and morphology on tissue reaction in vivo

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A fibrinogen-based precision microporous scaffold for tissue engineering

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Review of vascularised bone tissue-engineering strategies with a focus on co-culture systems

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Microporous nanofibrous fibrin-based scaffolds for bone tissue engineering

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Biomaterial-based scaffolds – current status and future directions

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Gingiva-Derived Mesenchymal Stem Cell-Mediated Therapeutic Approach for Bone Tissue Regeneration

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Bone Tissue Engineering: Current Strategies and Techniques—Part I: Scaffolds

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Controlling laser-induced jet formation for bioprinting mesenchymal stem cells with high viability and high resolution

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Concise Review: Bridging the Gap: Bone Regeneration Using Skeletal Stem Cell-Based Strategies—Where Are We Now?

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Distinct Tissue Formation by Heterogeneous Printing of Osteo- and Endothelial Progenitor Cells

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Targeting osteoclast-osteoblast communication

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Controlled Release Strategies for Bone, Cartilage, and Osteochondral Engineering—Part II: Challenges on the Evolution from Single to Multiple Bioactive Factor Delivery

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Reprogramming of mesenchymal stem cells derived from iPSCs seeded on biofunctionalized calcium phosphate scaffold for bone engineering

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Cell Sources for Bone Regeneration: The Good, the Bad, and the Ugly (But Promising)

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Layer-by-Layer Tissue Microfabrication Supports Cell Proliferation In Vitro and In Vivo

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Improving vascularization of engineered bone through the generation of pro-angiogenic effects in co-culture systems

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