Extracellular vesicles: A bright star of nanomedicine

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin‐Smith, G. K., et al. (2018) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2018.1535750 · Cited by 11,099

The biology , function , and biomedical applications of exosomes

Kalluri, R., & LeBleu, V. S. (2020) · Science · doi:10.1126/science.aau6977 · Cited by 10,770

Shedding light on the cell biology of extracellular vesicles

van Niel, G., D'Angelo, G., & Raposo, G. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.125 · Cited by 8,369

Extracellular vesicles: Exosomes, microvesicles, and friends

Raposo, G., & Stoorvogel, W. (2013) · Journal of Cell Biology · doi:10.1083/jcb.201211138 · Cited by 8,099

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

Colombo, M., Raposo, G., & Théry, C. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-101512-122326 · Cited by 6,186

Biological properties of extracellular vesicles and their physiological functions

Yáñez‐Mó, M., Siljander, P. R. ‐., Andreu, Z., Bedina Zavec, A., Borràs, F. E., Buzas, E. I., Buzas, K., Casal, E., Cappello, F., Carvalho, J., et al. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.27066 · Cited by 5,926

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Skog, J., Würdinger, T., van Rijn, S., Meijer, D. H., Gainche, L., Curry, W. T., Carter, B. S., Krichevsky, A. M., & Breakefield, X. O. (2008) · Nature Cell Biology · doi:10.1038/ncb1800 · Cited by 5,001

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., & Wood, M. J. A. (2011) · Nature Biotechnology · doi:10.1038/nbt.1807 · Cited by 4,930

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

Trajković, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B., & Simons, M. (2008) · Science · doi:10.1126/science.1153124 · Cited by 3,760

Engineered small extracellular vesicles as bioactive materials: Integrating engineering strategies for cargo loading and targeted delivery systems

Xu, H., Liu, R., Zhou, H., Kong, B., Shen, K., Zhao, T., Du, X., Zhang, H., Song, H., Guo, D., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.12.029 · Cited by 15

Global research trends in extracellular vesicles based on stem cells from 1991 to 2021: A bibliometric and visualized study

Lin, J., Yang, Z., Wang, L., Xing, D., & Lin, J. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.956058 · Cited by 14

Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering

Yang, T., Zhao, F., Zhao, J., Geng, J., Shao, C., Liu, J., Sheng, F., Zhou, L., Xu, H., & Jia, R. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.10.048 · Cited by 13

Revolutionizing cancer treatment via bioengineered extracellular vesicles: Exploring nanovesicles to fully synthetic solutions

Shao, M., Rodrigues, J. D. S., Sousa‐Oliveira, I., Moradialvand, M., Asadollahi, P., Veiga, F., Hameed, H., Jha, N. K., Sillanpää, M. E. T., Sethi, G., et al. (2024) · Applied Materials Today · doi:10.1016/j.apmt.2024.102395 · Cited by 13

Enhancing Gene Delivery to Breast Cancer with Highly Efficient siRNA Loading and pH-Responsive Small Extracellular Vesicles

Kim, G., Zhu, R., Yu, S., Fan, B., Jeon, H., Leon, J., Webber, M. J., & Wang, Y. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.4c01595 · Cited by 13

Extracellular vesicles: a new frontier in diagnosing and treating graft-versus-host disease after allogeneic hematopoietic cell transplantation

Wu, P., Wang, Z., Sun, Y., Cheng, Z., Wang, M., & Wang, B. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03297-y · Cited by 14

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Premcheska, S., Skirtach, A. G., & Kaczmarek, A. M. (2025) · Advanced NanoBiomed Research · doi:10.1002/anbr.202500003 · Cited by 13

Exosomal LncRNAs in Gastrointestinal Cancer: Biological Functions and Emerging Clinical Applications

Sun, Y., Sun, F., Jin, J., Xu, W., & Qian, H. (2023) · Cancers · doi:10.3390/cancers15030959 · Cited by 13

Roles of extracellular vesicles in ageing-related chronic kidney disease: Demon or angel

Yin, S., Zhou, Z., Fu, P., Jin, C., Wu, P., Ji, C., Shan, Y., Shi, L., Xu, M., & Qian, H. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106795 · Cited by 12

Engineered Extracellular Vesicles to Enhance Antigen Presentation for Boosting Light‐Driven Tumor Immunotherapy

Li, X., He, S., Luo, B., Li, P., Chen, X., Wu, M., Song, C. Q., Liu, C., Yang, T., Zhang, X., et al. (2023) · Small · doi:10.1002/smll.202303541 · Cited by 12

Regulation of regulated cell death by extracellular vesicles in acute kidney injury and chronic kidney disease

Zhou, Z., Shi, L., Chen, B., & Qian, H. (2023) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2023.12.006 · Cited by 13

Mesenchymal stem cells and their extracellular vesicles: new therapies for cartilage repair

Yang, H., Yang, H., Wang, Q., Ji, H., Qian, T., Qiao, Y., Shi, J., & Meng, C. (2025) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2025.1591400 · Cited by 12

Research hotspots and trends of mesenchymal stem cell-derived extracellular vesicles for drug delivery: a bibliometric and visualization analysis from 2013 to 2023

Zhao, T., Mu, Y., Deng, H., Liang, K., Zhou, F., Lin, Q., Cao, F., Zhou, F., & Yang, Z. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1412363 · Cited by 11

Overcoming drug resistance through extracellular vesicle-based drug delivery system in cancer treatment

Zheng, L. T., Chang, R., Liang, B., Wang, Y., Zhu, Y., Jia, Z., Fan, J., Zhang, Z., Du, B., & Kong, D. (2024) · Cancer Drug Resistance · doi:10.20517/cdr.2024.107 · Cited by 11

Engineered MEVs for photoreceptor-targeted delivery of USP25 to alleviate diabetic retinopathy

Sun, Y., Chen, S., Qi, X., Sun, Y., Jiang, Z., Chang, J., Ma, Y., Huang, J., You, B., & Sun, F. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03671-w · Cited by 13

Exosomal microRNAs mediating crosstalk between cancer cells and cancer-associated fibroblasts in the tumor microenvironment

Wang, Y., Liang, H., & Zheng, J. (2022) · Pathology - Research and Practice · doi:10.1016/j.prp.2022.154159 · Cited by 11

The antitumor effect of extracellular vesicles derived from cytokine-activated CD8+ T cells

Zhang, L., Meng, Y., An, Y., Yang, X., Wei, F., & Ren, X. (2024) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiae117 · Cited by 10

Maximizing arsenic trioxide's anticancer potential: Targeted nanocarriers for solid tumor therapy

Yang, S., Raza, F., Li, K., Qiu, Y., Su, J., & Qiu, M. (2024) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2024.114014 · Cited by 10

Emerging Frontiers in acute kidney injury: The role of extracellular vesicles

Li, S., Zhou, L., Huang, Y., & Tang, S. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.02.018 · Cited by 11

Abscopal Effect, Extracellular Vesicles and Their Immunotherapeutic Potential in Cancer Treatment

Salazar, A., Chavarria, V., Flores, I., Ruiz, S., de la Cruz, V. P., Sánchez‐García, F. J., & Pineda, B. (2023) · Molecules · doi:10.3390/molecules28093816 · Cited by 10

The role of exosomes in the stemness maintenance and progression of acute myeloid leukemia

Li, Q., Wang, M., & Liu, L. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115539 · Cited by 11

Extracellular vesicles and glycans

Janković, T., & Janković, M. (2024) · Biochemia Medica · doi:10.11613/bm.2024.020503 · Cited by 9

Cutting-edge insights into liver fibrosis: advanced therapeutic strategies and future perspectives using engineered mesenchymal stem cell-derived exosomes

Didamoony, M. A., Soubh, A. A., & Ahmed, L. A. (2025) · Drug Delivery and Translational Research · doi:10.1007/s13346-024-01784-7 · Cited by 9

Extracellular vesicles and their mimetics: clinical application prospects in medical aesthetics

Sun, Z., Li, J., Wu, Z., Zhang, J., Wang, T., Zheng, Y., Xu, X., Ding, W., Qian, H., & Tan, Y. (2025) · Burns & Trauma · doi:10.1093/burnst/tkaf033 · Cited by 11

Targeted delivery of engineered extracellular vesicles to simultaneously promote vascularization and muscle regeneration in ischemic limbs

Zhong, T., Gao, N., Niu, H. M., Guan, Y., Wen, J., Liu, Z., & Guan, J. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.113938 · Cited by 9

Biological Nanotherapeutics Derived From Human Umbilical Cord Mesenchymal Stem Cells: Mechanisms and Translational Potential in Multisystem Therapies for Regeneration and Oncology

Zhang, R., Xu, Z., Xu, S., Li, R., & Qian, H. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s550390 · Cited by 11

The molecular mechanism of human stem cell-derived extracellular vesicles in retinal repair and regeneration

Yang, M., & Peng, G.-H. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03319-2 · Cited by 11

Emerging Theragnostic Metal-Based Nanomaterials to Combat Cancer

Manikandan, S., Subbaiya, R., Saravanan, M., Barabadi, H., & Ramaswamy, A. (2021) · Nanotechnology in the life sciences · doi:10.1007/978-3-030-74330-7_11 · Cited by 9

Targeting cerebral diseases with enhanced delivery of therapeutic proteins across the blood-brain barrier

Bao, Y., & Lu, W. (2023) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2023.2193390 · Cited by 10

Exosomes: New Insights into the Pathogenesis of Metabolic Syndrome

Wang, N., Li, J., Hu, Z., Ngowi, E. E., Yan, B., & Qiao, A. (2023) · Biology · doi:10.3390/biology12121480 · Cited by 11

Better together: biomimetic nanomedicines for high performance tumor therapy

Mohammad, I. S., Kurşunluoğlu, G., Patel, A. K., Ishaq, H. M., Tunç, C. Ü., Kanarya, D., Rehman, M., Aydin, Ö. F., & Lifang, Y. (2025) · Beilstein Journal of Nanotechnology · doi:10.3762/bjnano.16.92 · Cited by 9

Emerging Roles of Extracellular Vesicles in the Pathogenesis, Diagnosis, and Therapy of Periodontitis

Fu, Y., Wang, M., Teng, R., & Li, A. (2025) · Biomedicines · doi:10.3390/biomedicines13102521 · Cited by 8

Engineering Bacterial Extracellular Vesicles as Nanoweapons to Fight against Bacterial Infections

Shi, Y., Li, Y., Liu, Z., Kong, X., Hu, X., Liu, X., Zhang, C., & Hu, H. (2026) · Research · doi:10.34133/research.1135 · Cited by 10

Fostering “Education”: Do Extracellular Vesicles Exploit Their Own Delivery Code?

Paolillo, M., Comincini, S., & Schinelli, S. (2021) · Cells · doi:10.3390/cells10071741 · Cited by 8

Research progress of odontogenic extracellular vesicles in regeneration of dental pulp

Li, Y., Liu, C., & Han, G. (2022) · Oral Diseases · doi:10.1111/odi.14451 · Cited by 8

Ribosomal proteins in hepatocellular carcinoma: mysterious but promising

Su, Q., Sun, H., Mei, L., Yan, Y., Ji, H., Chang, L., & Wang, L. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01316-3 · Cited by 9

Engineered extracellular vesicles for targeted FGF20 delivery enhance neuroplasticity and functional recovery in ischemic stroke

Guo, S., Wang, Z., Shi, R., Huang, P., Fang, Y., Chen, S., Huang, M. J., Hu, J. P., Lu, Y., Xu, X., et al. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114080 · Cited by 9

Current status and future prospects of mesenchymal stem cell-derived exosomes therapy for premature ovarian insufficiency

Zhang, X., & Wang, S. (2025) · Journal of Ovarian Research · doi:10.1186/s13048-025-01813-0 · Cited by 9

Extracellular vesicles in bone aging: therapeutic strategies and applications

Tang, L., Wang, P., Sheng, S., Yang, H., Jiang, Y., Jing, Y., Liu, H., & Su, J. (2025) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2025.58 · Cited by 9

Neural stem cell-derived exosomes: a cell-free transplant for potential cure of neurological diseases

Huang, J., Wang, W., Lin, W., CAI, H., ZHU, Z., Waqas, A., Zhang, Q. Y., LIU, J., Zhang, Y., Li, R., et al. (2024) · Biocell · doi:10.32604/biocell.2024.053148 · Cited by 7

Isolation, characterization and therapeutic potentials of exosomes in lung cancer: Opportunities and challenges

Shah, K. A., Ali, T., Hussain, Y., Dormocara, A., You, B., & Cui, J.-H. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.151707 · Cited by 8

Bioengineering extracellular vesicles as novel nanocarriers towards brain disorders

Wu, J., Ma, L., Sun, D., Zhang, X., Cui, J., Du, Y., Guo, Y., Wang, X., Di, L., & Wang, R. (2022) · Nano Research · doi:10.1007/s12274-022-4913-2 · Cited by 8

Potential clinical application of microRNAs in bladder cancer

Wang, P., Wei, X., Qu, X., & Zhu, Y. (2024) · Journal of Biomedical Research · doi:10.7555/jbr.37.20230245 · Cited by 7

Mesenchymal stem cell-derived exosome: The likely game-changer in stem cell research

Ocansey, D. K. W., Xu, X., ZHANG, L., & Mao, F. (2022) · Biocell · doi:10.32604/biocell.2022.018470 · Cited by 7

Visualization strategies of extracellular vesicles: Illuminating the invisible ‘dust’ in theranostics

Zhang, K., Hu, J., & Hu, Y. (2024) · Extracellular Vesicle · doi:10.1016/j.vesic.2024.100061 · Cited by 6

Optical biosensors for detection of exosomes

Vafadar, A., Maleki, M., Ehtiati, S., Moghadam, H. Z., & Savardashtaki, A. (2025) · Clinica Chimica Acta · doi:10.1016/j.cca.2025.120704 · Cited by 7

Extracellular Vesicles and Obesity

Wang, K., & Zeng, C. (2023) · Advances in experimental medicine and biology · doi:10.1007/978-981-99-1443-2_10 · Cited by 6

Mesenchymal stem cells and their extracellular vesicles in urological cancers: Prostate, bladder, and kidney

Saadh, M. J., Alhuthali, H. M., Aníbal, O. G., Asenjo‐Alarcón, J. A., Younus, D. G., Alhili, A., Adhab, Z. H., Alsalmi, O. A., Gharib, A. F., Pecho, R. D. C., et al. (2023) · Cell Biology International · doi:10.1002/cbin.12098 · Cited by 6

Engineered Nanoparticles for Theranostic Applications in Kidney Repair

Jin, C., Xue, L., Zhang, L., Yu, L., Wu, P., & Qian, H. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202402480 · Cited by 6

Cross-Scale Integration of Nano-Sized Extracellular Vesicle-Based Biomarker and Radiomics Features for Predicting Suspected Sub-Solid Pulmonary Nodules

Patel, N. D., Xu, W., Deng, Y., Jin, J., & Zhang, H. (2021) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2021.3097 · Cited by 6

The emerging role of extracellular vesicles in retinal diseases.

Sun, F., Xu, W., & Qian, H. (2021) · PubMed · Cited by 8

Nanometer-Sized and Near-Infrared-II Fluorescent Extracellular Vesicles for Noninvasive High-Contrast Imaging of Tumors with High EGFR Expression

Hong, Z., Liu, H.-M., Yu, Z., Chen, G., & Wu, M. Y. (2023) · ACS Applied Nano Materials · doi:10.1021/acsanm.3c01527 · Cited by 6

Antitumor Immunity: Role of NK Cells and Extracellular Vesicles in Cancer Immunotherapy

Prokopeva, A. E., Emene, C. C., & Gomzikova, M. O. (2023) · Current Issues in Molecular Biology · doi:10.3390/cimb46010011 · Cited by 6

Lipoaspirate fluid derived factors and extracellular vesicles accelerate wound healing in a rat burn model

Wu, Y., Hong, P., Liu, P., Zhang, Q., Zhang, Y., Baohua, Y., Liu, H., Liu, L., Tian, W., & Yu, M. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1185251 · Cited by 6

Safety Evaluation and Biodistribution of Fetal Umbilical Cord Mesenchymal Stem Cells-Derived Small Extracellular Vesicles in Sprague Dawley Rats

Krishnan, I., Vijakumaran, U., Ng, M. H., Law, J. X., Yusof, M. R. M., Thangarajah, T., Tan, G. C., Wong, Y. P., Kalyanasundaram, A., Mahmood, Z., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26146806 · Cited by 7

Extracellular Vesicles in Nonalcoholic Fatty Liver Disease: Mechanisms and Therapeutic Opportunities

Dong, Y., Xiong, L., Zhu, N., Wang, Z., Xia, H., Cheng, C., Huang, J., Han, Y., Rahman, A., Zhao, J., et al. (2025) · iNew Medicine · doi:10.1002/inm3.3 · Cited by 5

Bacterial extracellular vesicles as bioactive nanocarriers for wound treatment

Shi, Y., Zheng, Z., Li, Y., Wang, Y., Azevedo, H. S., Liu, X., Zhang, C., & Hu, H. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.01.007 · Cited by 6

LnCRNAs in the Regulation of Endometrial Receptivity for Embryo Implantation

Hasanabadi, H. E., Govahi, A., Chaichian, S., Mehdizadeh, M., Haghighi, L., & Ajdary, M. (2024) · JBRA · doi:10.5935/1518-0557.20240038 · Cited by 5

Basic Science and Principles of Stem Cells, Platelet‐Rich Plasma, and Exosomes

Lyles, E., Stegura, C., Broughton, L., Snyder, A., & Schlesinger, T. E. (2024) · Dermatological Reviews · doi:10.1002/der2.258 · Cited by 5

Agonist-induced extracellular vesicles contribute to the transfer of functional bombesin receptor-subtype 3 to recipient cells

Wang, Z., Wu, L., Wang, H., Zhang, Y., & Xiao, H. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-04114-z · Cited by 5

The emerging applications and advancements of Raman spectroscopy in pediatric cancers

Li, C., Feng, C., Xu, R., Jiang, B., Li, L., He, Y., Tu, C., & Li, Z. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1044177 · Cited by 5

Exosomes: A promising new strategy for treating osteoporosis in the future

Hu, S., Liang, Y., & Pan, X. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105571 · Cited by 6

Exosome-drug conjugates delivery: a promising strategy for ameliorating the pharmacokinetic profile of artesunate

Wang, D., Bai, Y., Cheng, G., Shen, S., Xiao, G., Ma, D., Zhao, G., Chen, W., Li, T., Zhang, L., et al. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1437787 · Cited by 5

Ulva lactuca extracellular vesicles protect against high-fat diet-induced intestinal damage via Nrf2/Keap1/HO-1 activation

Li, J., Li, Y., Song, X., Wang, Y., Zhang, Y., Gao, X., Tan, M., & Su, W. (2025) · Food & Function · doi:10.1039/d5fo03126e · Cited by 4

Extracellular Vesicles as Emerging Drug Delivery Platforms in Triple-Negative Breast Cancer: A Systematic Review

Tian, J., Chin, Y. Z., Ng, M. H., Pang, K. L., & Law, J. X. (2026) · International Journal of Nanomedicine · doi:10.2147/ijn.s570252 · Cited by 5

Exosome-mediated lymphatic regeneration: Mechanisms, therapeutic strategies, and translational opportunities

Li, Y., Xu, Z., Kusumbe, A. P., & Chen, J. (2026) · Dental Research · doi:10.1016/j.dtrs.2026.100029 · Cited by 4

Dysregulated Repair in Aging and Disease: Extracellular Vesicles as an Emerging Protective Strategy

Calabrò, A., Accardi, G., Batista-Duharte, A., Ligotti, M. E., Pera, A., Puleo, C., Soresi, M., Candore, G., & Aiello, A. (2026) · Cells · doi:10.3390/cells15080662 · Cited by 5

The role of extracellular vesicles in intercellular communication within the oral cavity

Semlali, A., Al-zharani, M., & Al-Ansari, J. (2026) · Journal of Oral Microbiology · doi:10.1080/20002297.2026.2673760 · Cited by 6

Therapeutically Harnessing Tumor Cell-Derived Extracellular Vesicles for Multiple Myeloma: Recent Advances and Future Perspectives

Xiao, S., Chen, L., Chen, Z., & Li, Q. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16111439 · Cited by 4

Galangin exosomes induce cell apoptosis through miR-10b/P53 axis in gastric cancer

Li, Q., Zhang, Y., Shi, B., Lin, C., Feng, Q., Zhou, H., Hao, M., Ding, Y., Ma, C., Mu, J., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-95908-9 · Cited by 4

Therapeutic potential of extracellular vesicle-polyphenol nanoplatform in regenerative medicine

Ma, M., Wu, Q., Wang, T., Ma, Y., Le, F., Wang, Y., Jiang, L., Gu, Z., & Hao, Z. (2025) · Nano Materials Science · doi:10.1016/j.nanoms.2025.05.008 · Cited by 5

Melanoma extracellular vesicles inhibit tumor growth and metastasis by stimulating CD8 T cells

Dan, Y., Ma, J., Long, Y., Jiang, Y., Fang, L., & Bai, J. (2024) · Molecular Immunology · doi:10.1016/j.molimm.2024.03.003 · Cited by 4

The role of extracellular vesicles in pyroptosis-mediated infectious and non-infectious diseases

Zhang, C., Lu, D.-C., Liu, Y., Wang, L., Sethi, G., & Ma, Z. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112633 · Cited by 5

Regulation and Clinical Application of Exosomes in Venous Thrombosis

Shao, F., He, R., Yang, J., Pang, Y., Sun, Z., Zhang, B., & Jin, S. H. (2025) · Angiology · doi:10.1177/00033197251319597 · Cited by 4

Apoptotic vesicles act as natural antibacterial agents for infected wound healing by interfering with the bacterial catabolic process

Wang, M., Gui, H., Hu, Z., Wu, P., Zhao, W., Liu, Z., & Wang, X. (2025) · Nano Research · doi:10.26599/nr.2025.94907776 · Cited by 4

Mesenchymal stem cell-derived extracellular vesicles: emerging concepts in the treatment of spinal cord injury.

Wang, S., Du, C., & Li, G. (2023) · PubMed Central · Cited by 5

Treatment with Exosomes Derived from Mesenchymal Stem Cells: A New Window of Healing Science in Regenerative Medicine

Hormozi, A., Hasanzadeh, S., Ebrahimi, F., Daei, N., Hajimortezayi, Z., Mehdizadeh, A., & Zamani, M. (2023) · Current Stem Cell Research & Therapy · doi:10.2174/1574888x18666230824165014 · Cited by 4

Modulatory effects of cancer stem cell-derived extracellular vesicles on the tumor immune microenvironment

Li, X., Zhang, C., Yue, W., & Jiang, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1362120 · Cited by 4

Exosome, an important transmitter in the drug resistance of non-small cell lung cancer

Ji, H., Zhang, L., & Ye, L. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1539047 · Cited by 3

Revealing the complexity of the epicardial secretome

Oliveira, C. C., Córdoba, J., Pearson, J. R., Guruceaga, E., Marín‐Sedeño, E., López-Moreno, M. F., Guadix, J. A., García‐Caballero, M., Pérez-Pomares, J. M., & Ruiz‐Villalba, A. (2025) · Scientific Reports · doi:10.1038/s41598-025-24980-y · Cited by 4

Neonatal Sepsis-Induced Coagulopathy: An Evolving Frontier at the Crossroads of Inflammation and Hemostasis

Sokou, R., Lianou, A., Gounari, E. A., Tsantes, A. G., Bonovas, S., Nikolopoulos, G. K., Tsantes, A. Ε., & Iacovidou, N. M. (2026) · Seminars in Thrombosis and Hemostasis · doi:10.1055/a-2823-8395 · Cited by 3

Biological Cargo: Exosomes and their Role in Cancer Progression and Metastasis

Tripathi, S., Sharma, Y., & Kumar, D. (2024) · Current Topics in Medicinal Chemistry · doi:10.2174/0115680266304636240626055711 · Cited by 3

Sparstolonin B potentiates the antitumor activity of nanovesicle-loaded drugs by suppressing the phagocytosis of macrophages in vivo

Zhang, Y., Mou, Z., Song, W., He, X., Qin, Y., Wang, Z., Mao, X., Wang, W., Xu, Y., Shen, Y., et al. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-03001-6 · Cited by 3

Extracellular vesicles in thalassemia: Mechanisms, implications, and therapeutic potential

Jiskani, S. A. (2024) · Aspects of Molecular Medicine · doi:10.1016/j.amolm.2024.100061 · Cited by 3

Recent Advances in the Development of Membrane-derived Vesicles for Cancer Immunotherapy

Xiao, Y., Wu, M., Xue, C., & Wang, Y. (2023) · Current Drug Delivery · doi:10.2174/1567201820666230504120841 · Cited by 3

Apoptotic bodies encapsulating Ti2N nanosheets for synergistic chemo-photothermal therapy

Yang, K., Ren, D., Wang, Z., Dong, Q., Xu, M., Wang, T., & Wang, Z. (2024) · Nanotechnology · doi:10.1088/1361-6528/ad5690 · Cited by 3

Electrochemical Microfluidic Immunosensor Based on Porous Nanomaterial Towards to Claudin7 Determination for Colorectal Cancer DiagnosisPreprint

Ortega, F. G., Gómez, G. E., Boni, C., García, I. C., Garrido-Navas, M. C., D'Vries, R. F., Vallejos, M. P. M., Fernández, M. J. S., Messina, G. A., Expósito, J., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4125877 · Cited by 3

Real-Time Isolation and Versatile Detection for Extracellular Vesicles Based on Ordered Porous Layer Interferometry

Wu, F., Li, Y., Zhang, L., Zhou, Y., Xu, Y., Cai, Y., Ding, L., Zhang, L., Wang, Y., & Qian, H. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.4c07108 · Cited by 2

Oral Administration of Ginseng Extracellular Vesicle-Loaded Sodium Alginate Hydrogel for Modulating Macrophage-Mediated Inflammation in Ulcerative Colitis

Yan, B., Liu, H., Wang, J., & Gao, M. (2025) · BioNanoScience · doi:10.1007/s12668-025-02054-7 · Cited by 2

Therapeutic Applications of Mesenchymal Stem Cell‐Derived Extracellular Vesicles in Diabetic Neuropathy; Challenges and Future Prospective

Shi, L., Che, H. X., Yang, H., Li, Y., & Jin, Y. Y. (2025) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.70459 · Cited by 2

Targeted delivery of Prussian blue modified exosomes to CD90-expressing synovial fibroblasts for Rheumatoid arthritis immunotherapy

Yang, H., Hu, X., Zhu, F., Zhao, B., Wang, Y., Deng, Y., Jin, F., Zhang, Y., Lin, S., & Mei, X. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102580 · Cited by 3

Detecting Erythrocyte-Derived Extracellular Vesicles Generated from Blood Pump Flow and the Challenges Encountered

Foster, K. M., Banayosy, A. M. E., Banayosy, A. E., Setiadi, H., Bajpai, V. K., & O’Rear, E. A. (2026) · Cells · doi:10.3390/cells15070642 · Cited by 2

Engineered extracellular vesicles and cancer therapy

Liao, S., Yan, Z., Zhao, W., & Li, N. (2022) · Scientia Sinica Vitae · doi:10.1360/ssv-2021-0451 · Cited by 2

Insights into the complex interactions between Rab22a and extracellular vesicles in cancers

Huang, S., Bao, Y., Kong, L., Gao, S., & Hua, C. (2023) · Inflammation Research · doi:10.1007/s00011-023-01821-0 · Cited by 2

Maximizing oxaliplatin's impact on EGFR + colorectal cancer through targeted extracellular vesicles

Chien, S., Huang, Y.-J., Huang, M., Fang, Y., Chao, S.-W., Li, C.-T., Jhang, W.-Y., Hsu, Y.-H., Wang, S.-H., & Chuang, C.-H. (2024) · Cancer Nanotechnology · doi:10.1186/s12645-024-00284-0 · Cited by 2

Extracellular Vesicles: Therapeutic Delivery

Ma, R., Chen, L., & Hu, G. (2024) · Springer eBooks · doi:10.1007/978-3-031-68237-7_47 · Cited by 2

Homologous Targeting and Adhesion Abilities of Cellular Microvesicles for Enhanced Intravesical Therapy of Bladder Cancer

Fan, Q., Wang, L., Bi, L., Han, X., Yan, J., Song, P., Wan, X., Wang, Y., Kang, Y., Ding, X., et al. (2023) · Advanced Therapeutics · doi:10.1002/adtp.202300280 · Cited by 2

Extracellular Vesicles: The Challenges on the Way and Engineering Perspectives

Attia, N., Ibrahim, H. G., Abdulla, H., Mashal, M., Puras, G., & Pedraz, J. L. (2024) · Springer eBooks · doi:10.1007/978-981-99-7119-0_56 · Cited by 1

New Challenges and Opportunities: Extracellular Vesicles in Biological and Biochemical Processes

Giusti, I., & Bavisotto, C. C. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26073395 · Cited by 1

Intracellular transport efficiencies of bacterial extracellular vesicles containing cytosolic and membrane-associated protein cargos

Park, A.-R., Park, J., & Lim, S. I. (2025) · Biotechnology and Bioprocess Engineering · doi:10.1007/s12257-025-00227-5 · Cited by 1

Extracellular Vesicles: Diagnostic and Therapeutic Applications in Cancer

Bella, M. A. D., & Taverna, S. (2024) · Biology · doi:10.3390/biology13090716 · Cited by 24

Engineering Extracellular Vesicles as Nanotherapeutics for Regenerative Medicine

Ramasubramanian, L., Kumar, P., & Wang, A. (2019) · Biomolecules · doi:10.3390/biom10010048 · Cited by 102

Preparation and characterization of extracellular vesicles and their cutting-edge applications in regenerative medicine

Tang, P., Song, F., Chen, Y., Gao, C., Ran, X., Li, Y., Chen, Z., Zhang, Z., Wei, W., Peng, Z., et al. (2024) · Applied Materials Today · doi:10.1016/j.apmt.2024.102084 · Cited by 25

Engineered Extracellular Vesicles as a Reliable Tool in Cancer Nanomedicine

Susa, F., Limongi, T., Dumontel, B., Vighetto, V., & Cauda, V. (2019) · Cancers · doi:10.3390/cancers11121979 · Cited by 103

Theranostic Potential of Extracellular Vesicles

Afkhami, H., Razavi, Z. S., Yousefi, M. H., Yang, P., Reza, M. A. S., & Sheykhhasan, M. (2026) · Molecular and translational medicine · doi:10.1007/978-3-032-23810-8_11