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Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

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ROS function in redox signaling and oxidative stress

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Oxidative stress: oxidants and antioxidants

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Thiol–Ene Click Chemistry

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Glutathione Metabolism and Its Implications for Health

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Association of reactive oxygen species levels and radioresistance in cancer stem cells

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Functional Nanomaterials for Phototherapies of Cancer

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Antioxidants Maintain Cellular Redox Homeostasis by Elimination of Reactive Oxygen Species

He, L., He, T., Farrar, S., Ji, L., Liu, T., & Ma, X. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000485089 · Cited by 2,207

Glutathione synthesis

Lu, S. C.-L. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2012.09.008 · Cited by 2,192

A Redox‐Triggered Polymeric Nanoparticle for Disrupting Redox Homeostasis and Enhanced Ferroptosis

Li, Y., Han, S., Zhao, Y., Yan, J., Luo, K., Li, F., He, B., Sun, Y. Y., Li, F., & Liang, Y. (2024) · Small · doi:10.1002/smll.202404299 · Cited by 17

The safe Laccase@ZIF-8-prodrug system with GSH redox cycle for effective targeted cancer therapy with low off-target toxicity

Zhou, Y., Zhang, C., Wang, Y., Zhang, J., Yan, X., You, S., Qi, W., Su, R., & He, Z. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.112853 · Cited by 17

GSH‐Responsive Mn 2+ Burst Nanoboxes as Mitophagy Intervention Agents Augment Ferroptosis and Chemoimmunotherapy in Triple‐Negative Breast Cancer

Zhang, G., Duan, J., Yu, F., Qi, Y., Zhao, S., Zhao, Y., Han, X., Liu, H., Sang, Y., & Yu, D. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202500491 · Cited by 16

GSTM1 suppresses cardiac fibrosis post-myocardial infarction through inhibiting lipid peroxidation and ferroptosis

Chen, K.-J., Zhang, Y., Zhu, X.-Y., Yu, S., Xie, Y., Jin, C. W., Shen, Y., Zhou, S.-Y., Dai, X.-C., Su, S., et al. (2025) · Military Medical Research · doi:10.1186/s40779-025-00610-6 · Cited by 17

Advances in hydrogel systems for bone regeneration: trends, innovations, and prospects

Han, Y., Liu, J., Hu, C., Wang, Y., & He, C. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb02041g · Cited by 18

Glutathione responsive nanomedicine leverages tumor redox imbalance for targeted cancer theranostics

Sadda, R. R. E. (2026) · Discover Oncology · doi:10.1007/s12672-026-04456-9 · Cited by 21

Metal–Phenolic Networks-Based Nanozyme Reprograms Tumor Metabolism and Immunosuppressive Microenvironment to Enhance Ferroptosis and Potentiate Cancer Immunotherapy

Ma, R., Deng, Q., Lin, Y., Gu, S., Su, Q., Wang, Y., Deng, P., Fu, Z., Yang, Y., & Dai, Y. (2026) · ACS Nano · doi:10.1021/acsnano.5c18701 · Cited by 16

Fabrication of phenyl boronic acid modified pH-responsive zinc oxide nanoparticles as targeted delivery of chrysin on human A549 cells

Mahalanobish, S., Kundu, M., Ghosh, S., Das, J., & Sil, P. C. (2022) · Toxicology Reports · doi:10.1016/j.toxrep.2022.04.017 · Cited by 17

Glutathione S-Transferases S1, Z1 and A1 Serve as Prognostic Factors in Glioblastoma and Promote Drug Resistance through Antioxidant Pathways

Cheng, B., Wang, Y., Ayanlaja, A. A., Zhu, J., Kambey, P. A., Qiu, Z., Zhang, C., & Hu, W. (2022) · Cells · doi:10.3390/cells11203232 · Cited by 16

Comparative bioactivity analysis of hydro-methanolic extracts of root, leaf, and inflorescence of Tupistra nutans Wall. ex Lindl: An in vitro study on antioxidant and anti-hepatocellular carcinoma activity

Roy, A. C., Prasad, A., Singh, S., Priya, K., & Ghosh, I. (2023) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2023.102819 · Cited by 16

Manganese-induced neurological pyroptosis: Unveiling the mechanism through the ROS activaed Caspase-3/GSDME signaling pathway

He, J., Ma, X., Zhang, J., Yang, Y., Qin, H., Chen, H., Wei, S., Li, F., Wang, J., Liang, G., et al. (2023) · Food and Chemical Toxicology · doi:10.1016/j.fct.2023.114322 · Cited by 16

Bio-responsive Au-miR-183 inhibitor enhances immunotherapy in hepatocellular carcinoma by inducing immunogenic cell death

Yin, L., Wei, Y., Liu, Y., Mo, X., Song, J., & Cai, W. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.02.036 · Cited by 16

Mitochondrial GCN5L1 acts as a novel regulator for iron homeostasis to promote sorafenib sensitivity in hepatocellular carcinoma

Hu, X., Zhang, P., Li, S., Zhang, J., Wang, D., Wang, Z., Zhu, L., & Wang, L. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05404-3 · Cited by 16

Photocatalysis-promoted tumor ferroptosis enabled by MOF-derived black TiO2

Zhuang, H., Wang, L., Shao, S., Jing, H., Xue, P., Bai, T., Deng, J., Zeng, X., Qin, X., & Yan, S. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.154204 · Cited by 16

Fibroin nanodisruptor with Ferroptosis-Autophagy synergism is potent for lung cancer treatment

Shu, L., Luo, P., Chen, Q., Liu, J., Huang, Y., Wu, C., Pan, X., & Huang, Z. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.124582 · Cited by 16

α-Arbutin ameliorates UVA-induced photoaging through regulation of the SIRT3/PGC-1α pathway

Lu, F. Y., Zhou, Q., Liang, M., Liang, H., Yu, Y., Yang, L., Zhang, Y., Lu, L., Zheng, Y., Hao, J., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1413530 · Cited by 17

Cu-Mn nanocomposite for enhanced tumor cuproptosis achieved by remodeling the tumor microenvironment and activating the antitumor immunogenic responses

Fan, M., Yang, P., Huo, L., Bao, J., Tan, M., Zeng, J., Zhu, S., Liu, M., Zhao, J., Miao, W., et al. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.01.044 · Cited by 16

A cascade reaction nanoplatform with magnetic resonance imaging capability for combined photothermal/chemodynamic/gas cancer therapy

Wang, J., Guo, Y., Wu, X., Ma, Y., Qiao, Q., Li, L., Liao, T., Kuang, Y., & Li, C. (2025) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2025.101223 · Cited by 15

Oxidative Stress and Redox Signaling in Gastric Cancer: From Mechanisms to Therapeutic Implications

Chen, Z., Fan, J., Chen, X., Yang, K., & Wang, K. (2025) · Antioxidants · doi:10.3390/antiox14030258 · Cited by 15

Hydrogel-enabled ROS-GSH modulation for sustained copper-mediated chemodynamic therapy of oral squamous cell carcinoma

Wu, S., Xia, X., Zhou, R., & Zhao, H. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.113772 · Cited by 15

Role of ferroptosis in breast cancer: Molecular mechanisms and therapeutic interventions

Wang, W., Liu, Z., Li, J., Xu, J., Guo, Y., Zhang, J.-X., Chu, T., Feng, Z.-F., Jiang, Q., & Wu, D. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.111869 · Cited by 15

Targeting the redox-programmed cell death axis in breast cancer: from molecular mechanisms to therapeutic resistance

Wen, Y., Lin, Z., Jiang, Z., Li, Y., & Wu, T. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02743-y · Cited by 16

Hydrogen sulfide in cancer therapy: Intelligent delivery platforms and synergistic therapeutic paradigms

Yang, N., Cai, Y., Sun, S., Nie, J., Gong, F., Pei, Z., & Cheng, L. (2025) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2025.115717 · Cited by 15

Emerging nano-delivery systems for targeting mitochondria

Burska, A. N., Raish, K., Bayandy, D., & Paunov, V. N. (2025) · Nanoscale · doi:10.1039/d5nr03935e · Cited by 18

A disulfide-induced supra-amphiphilic co-assembly for glycosylated pro-drug-photosensitizer nanoparticles in combination therapies

Jin, W., Chen, Z., Yang, S., Qu, Y., Pei, Y., & Pei, Z. (2022) · Chemical Communications · doi:10.1039/d2cc04777b · Cited by 15

Flash dissolving nanofiber membranes for chemo/cascade chemodynamic therapy of oral cancer

Kim, S., Hao, Q., Jeong, D. I., Huh, J. W., Choi, Y. E., & Cho, H. (2023) · Materials & Design · doi:10.1016/j.matdes.2023.112063 · Cited by 15

The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis

Yang, R., Zhou, Y., Zhang, T., Wang, S., Wang, J., Cheng, Y., Li, H., Jiang, W., Yang, Z., & Zhang, X. (2023) · PLoS Biology · doi:10.1371/journal.pbio.3001862 · Cited by 15

Therapeutic Role of Synthetic Lethality in ARID1A -Deficient Malignancies

Hein, K. Z., Stephen, B., & Fu, S. (2023) · Journal of Immunotherapy and Precision Oncology · doi:10.36401/jipo-22-37 · Cited by 17

Glutathione supplementation improves fat graft survival by inhibiting ferroptosis via the SLC7A11/GPX4 axis

Li, Z., Lu, J., Dong, Z., Liang, J., Li, S., Han, W., Cui, T., & Liu, H. (2024) · Stem Cell Research & Therapy · doi:10.1186/s13287-024-03644-0 · Cited by 15

Synergistic suppression of ovarian cancer by combining NRF2 and GPX4 inhibitors: in vitro and in vivo evidence

Li, N., Jiang, X., Zhang, Q., Huang, Y., Wei, J., Zhang, H., & Luo, H. (2024) · Journal of Ovarian Research · doi:10.1186/s13048-024-01366-8 · Cited by 15

New Janus Organic Type-I Photosensitizer Capable of Transforming Glutathione from Opponent to Ally for Assisting Photodynamic Therapy

Wang, H., Yang, Z., Zhang, K., Wang, W., Lin, F., Huang, H., Qin, W., Chi, Z., & Yang, Z. (2024) · ACS Materials Letters · doi:10.1021/acsmaterialslett.3c01210 · Cited by 15

Targeting nanoplatform synergistic glutathione depletion-enhanced chemodynamic, microwave dynamic, and selective-microwave thermal to treat lung cancer bone metastasis

Shu, M., Wang, J., Xu, Z., Lu, T., He, Y., Li, R., Zhong, G., Yan, Y., Zhang, Y., Chu, X., et al. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.04.016 · Cited by 17

Silica nanoparticles triggered epithelial ferroptosis via miR-21-5p/GCLM signaling to contribute to fibrogenesis in the lungs

Lv, S., Li, Y., Li, X., Zhu, Y., Zhu, Y., Guo, C., & Li, Y. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.111121 · Cited by 15

Comprehensive analyses show the enhancement effect of exogenous melatonin on fluroxypyr-meptyl multiple phase metabolisms in Oryza sativa for reducing environmental risks

Chen, Z. J., Li, S. Y., Qu, Y. N., Ai, G., Wang, Y. H., Pan, D., Wang, H. W., Lü, D., & Liu, X. L. (2024) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2024.106021 · Cited by 15

Advances in photo-responsive hydrogel integrated with biomedical materials for antitumor applications

Chen, Z., Chen, T., Guo, B., & Yang, F. (2024) · European Polymer Journal · doi:10.1016/j.eurpolymj.2024.113431 · Cited by 15

Ferroptosis: insight into the treatment of hepatocellular carcinoma

Liao, C., He, Y.-W., Luo, X.-N., & Deng, G.-L. (2024) · Cancer Cell International · doi:10.1186/s12935-024-03559-z · Cited by 14

Breaking barriers: Nitric oxide-releasing nanocomplexes for collagen degradation and enhanced αPD-L1 immunotherapy in deep tumor

Lee, J., Cho, H., Kim, J., Lim, J., Kang, Y., & Kim, W. J. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.02.072 · Cited by 15

Activatable Sulfur Dioxide Nanosonosensitizer Enables Precisely Controllable Sono‐Gaseous Checkpoint Trimodal Therapy for Orthotopic Hepatocellular Carcinoma

Liang, J., Cheng, G., Qiu, L., Xue, L., Xu, H., Qiao, X., Guo, N., Xiang, H., Chen, Y., & Ding, H. (2024) · Advanced Science · doi:10.1002/advs.202409442 · Cited by 14

Ferrostatin supplementation improves microalgal activities and nutrient removal in wastewater under high temperature shock: From ferroptosis-like inhibition to enhanced oxidation resistance

Liu, Y., Qiu, S., Huang, H., Wu, Z., & Ge, S. (2024) · Water Research · doi:10.1016/j.watres.2024.123033 · Cited by 14

Iron-Dependent Cell Death: Exploring Ferroptosis as a Unique Target in Triple-Negative Breast Cancer Management

Tan, L.-K., Liu, J., Ma, C., Huang, S., He, F.-H., Long, Y., Zheng, Z., Liang, J.-L., Xu, N., Wang, G.-H., et al. (2025) · Cancer Management and Research · doi:10.2147/cmar.s503932 · Cited by 16

Innovative sarcoma therapy using multifaceted nano-PROTAC-induced EZH2 degradation and immunity enhancement

Chen, Z., Tai, Y., Deng, C., Sun, Y., Chen, H., Luo, T., Lin, J., Chen, W., Xu, H., Song, G., et al. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123344 · Cited by 14

Metal ions-induced programmed cell death: how does oxidative stress regulate cell death?

Wang, X., Liu, Z., & Lin, C. (2025) · Life Sciences · doi:10.1016/j.lfs.2025.123688 · Cited by 16

Sevoflurane exposure triggers ferroptosis of neuronal cells initiated by the activation of ATM/p53 in the neonatal mouse brain via JNK/p38 MAPK-mediated oxidative DNA damage

Gu, W., Pan, T., Wang, X., Kang, L., Liu, N., Piao, M., & Feng, C. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114866 · Cited by 16

GPX4 in triple-negative breast cancer: A key regulator of ferroptosis and therapeutic target.

Baskar, G. (2025) · Cancer Genetics · doi:10.1016/j.cancergen.2025.06.009 · Cited by 14

Intersection of ferroptosis and nanomaterials brings benefits to breast cancer

Gao, J., Ma, N., Ni, S., & Han, X. F. (2025) · Cell Biology and Toxicology · doi:10.1007/s10565-025-10067-x · Cited by 17

Cross-linked selenolipoic acid nanoplatform modulates intracellular and extracellular reactive oxygen species for cancer immunotherapy

Tan, Y., Zhang, S., Cheng, Y., & Zhang, S. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114130 · Cited by 14

Metabolic Hijacking by Engineered Probiotics Reprograms Tumor Metabolism and Immune Microenvironment for Self-Reinforcing Photodynamic Immunotherapy

Qin, S., Wang, Q., Zhang, Z., Gu, J., He, G., Zeng, F., Chen, R., He, B., Wang, Y., Wang, M., et al. (2025) · Journal of the American Chemical Society · doi:10.1021/jacs.5c10242 · Cited by 14

Beyond Protein Building Blocks: A Review of Biological Roles and Therapeutic Potential of Free Amino Acids

Petkova, D., Stoyanova, S., Dinkov, G., & Bogdanov, M. G. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311264 · Cited by 18

SETD1A ‐mediated H3K4me3 methylation upregulates lncRNA HOXC‐AS3 and the binding of HOXC‐AS3 to EP300 and increases EP300 stability to suppress the ferroptosis of NSCLC cells

Shi, Z., Zhang, H., Shen, Y., Zhang, S., Zhang, X., Xu, Y., & Sun, D. (2023) · Thoracic Cancer · doi:10.1111/1759-7714.15037 · Cited by 14

Effects of Skeleton Structure of Mesoporous Silica Nanoadjuvants on Cancer Immunotherapy

Tan, J., Ding, B., Chen, H., Meng, Q., Li, J., Yang, C., Zhang, W., Li, X., Han, D., Zheng, P., et al. (2023) · Small · doi:10.1002/smll.202305567 · Cited by 14

Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1α Pathway

Lu, Z., Song, C., Zou, S., Pan, S., Lai, K., Li, N., & Geng, Q. (2023) · Current Issues in Molecular Biology · doi:10.3390/cimb45120616 · Cited by 14

Porphyrin‐Based Nanozymes for Biomedical Applications

Cheng, E., Li, B., & Zou, Q. (2023) · Advanced Therapeutics · doi:10.1002/adtp.202300329 · Cited by 14

Design of a nanozyme-based magnetic nanoplatform to enhance photodynamic therapy and immunotherapy

Bai, C. G., Liu, J., Bai, L., Yao, D., Li, X., Zhang, H., & Guo, D. M. (2023) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2023.12.018 · Cited by 15

Multifunctional fluorescent probe for simultaneous revealing Cys and ONOO– dynamic correlation in the ferroptosis

Liu, X., Zhu, J., Zhang, Q., Hu, H., Zhang, W., Xu, H., Huang, Y., Xie, J., Liu, H., Feng, Y., et al. (2024) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2024.124248 · Cited by 14

Biodegradable Manganese-Containing Mesoporous Silica Nanoparticles for Precisely Controlled Quercetin Delivery

Guo, Z.-Y., Luan, X., Wang, T., Hu, L., & Zhang, W. (2024) · ACS Applied Nano Materials · doi:10.1021/acsanm.4c00168 · Cited by 14

Long non‑coding RNA lung cancer‑associated transcript 1 regulates ferroptosis via microRNA‑34a‑5p‑mediated GTP cyclohydrolase 1 downregulation in lung cancer cells

Tai, F., Zhai, R., Ding, K., Zhang, Y., Yang, H., Li, H., Wang, Q., Cao, Z., Ge, C., Fu, H., et al. (2024) · International Journal of Oncology · doi:10.3892/ijo.2024.5652 · Cited by 17

Maleimide functionalized polycaprolactone micelles for glutathione quenching and doxorubicin delivery

Babanyinah, G. K., Bhadran, A., Polara, H., Wang, H., Shah, T. V., Biewer, M. C., & Stefan, M. C. (2024) · Chemical Science · doi:10.1039/d4sc01625d · Cited by 14

Investigating the protective effects of Astragalus polysaccharides on cyclophosphamide-induced bone marrow suppression in mice and bone mesenchymal stem cells

Wang, W., Zhang, K., Dai, L., Hou, A., Meng, P., & Ma, J. (2024) · Molecular Immunology · doi:10.1016/j.molimm.2024.05.008 · Cited by 14

Dual‐Responsive Nanoreactor Initiates In Situ Generation of Copper Complex for Paraptosis‐Mediated Tumor Chemo‐Immunotherapy

Niu, M., Li, Q., Huang, Q., Liu, L., Qin, Y., Wu, C., Cheng, S., & Zhang, X. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202404822 · Cited by 15

IGF2BP3 suppresses ferroptosis in lung adenocarcinoma by m6A-dependent regulation of TFAP2A to transcriptionally activate SLC7A11/GPX4

Li, P., Chu, D., Ding, G., Qin, D., Bu, Y., & Tian, B. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05068-z · Cited by 14

Novel insights and future perspectives on the nanomedicine-mediated synergistic anticancer effect of the combination of ferroptosis and photothermal therapy

Qi, H., Wang, H., Wang, L., Sun, D., Wei, M., & Li, Z. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.156921 · Cited by 14

Ferroptosis in schizophrenia: Mechanisms and therapeutic potentials (Review)

Lv, S., & Luo, C. (2024) · Molecular Medicine Reports · doi:10.3892/mmr.2024.13402 · Cited by 14

The evolution of S-nitrosylation detection methodology and the role of protein S-nitrosylation in various cancers

Liang, F., Wang, M., Li, J., & Guo, J. (2024) · Cancer Cell International · doi:10.1186/s12935-024-03568-y · Cited by 14

Ferroptosis: A novel cell death modality as a synergistic therapeutic strategy with photodynamic therapy

Wang, Y., Xu, Y., Qu, Y., Jin, Y., Cao, J., Zhan, J., Li, Z., Chai, C., Huang, C., & Li, M. (2024) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2024.104463 · Cited by 14

Self-amplifying ROS-responsive SN38 prodrug nanoparticles for combined chemotherapy and ferroptosis in cancer treatment

Yu, Q., Liu, N., Wang, F., Gao, Z., Luo, C., Tian, C., & Kamei, K. (2025) · Carbon · doi:10.1016/j.carbon.2025.120099 · Cited by 14

Recent advances in near-infrared-II (NIR-II) small molecule fluorophores for cancer theranostics

Zhu, Q., Nie, J., Li, Y., Li, N., Kong, X., Zhou, H., & Wu, J. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb01249j · Cited by 14

Alleviation of Tris(2-chloroethyl) Phosphate Toxicity on the Marine Rotifer Brachionus plicatilis by Polystyrene Microplastics: Features and Molecular Evidence

Ma, W., Sun, Z., Zhang, X., Tang, X., & Tang, X. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094934 · Cited by 14

Hypoxia responsive fucoidan-based micelles for oxidative stress-augmented chemotherapy

Li, L., Wang, B., Zhang, Q., Song, P., Jiang, T.-Z., & Zhao, X. (2022) · European Polymer Journal · doi:10.1016/j.eurpolymj.2022.111340 · Cited by 11

Cu-Hemin Nanosheets and Indocyanine Green Co-Loaded Hydrogel for Photothermal Therapy and Amplified Photodynamic Therapy

Shu, Z., Wang, S., Liu, C., Lyu, M., & Huang, Q. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.918416 · Cited by 14

Grape seed extract proanthocyanidin antagonizes aristolochic acid I-induced liver injury in rats by activating PI3K-AKT pathway

Wang, S., Liu, Z., Wang, Y., Shi, B., Jin, Y., Wang, Y., Jiang, X., Song, M., & Yu, W. (2022) · Toxicology Mechanisms and Methods · doi:10.1080/15376516.2022.2103479 · Cited by 14

Supramolecular Coassembled Peptide Hydrogels for Efficient Anticancer Therapy by RNS‐Based PDT and Immune Microenvironment Regulation

Wang, D., Li, H., Wang, D., Hao, Y., Gui, H., Liu, J., Zhang, Y., Liu, J., & Yang, C. (2022) · Macromolecular Bioscience · doi:10.1002/mabi.202200359 · Cited by 14

Renal-clearable and tumor-retained nanodots overcoming metabolic reprogramming to boost mitochondrial-targeted photodynamic therapy in triple-negative breast cancer

Yao, D., Wang, Y., Dong, X., Chen, Y., Ji, D., Zou, R., Huang, Y., Huang, W., & Wang, D. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03264-7 · Cited by 14

The Acetyltransferase ARD1 Induces Glutathione Synthesis to Facilitate Ferroptosis Evasion in Hepatocellular Carcinoma

Liu, Y., Liu, F., Liu, J., Cairang, D., Li, X., Xia, P., Ma, W., Wu, T., Gongye, X., Zhang, Z., et al. (2025) · Cancer Research · doi:10.1158/0008-5472.can-24-4015 · Cited by 13

Harnessing engineered metal-phenolic networks as theranostic nanomedicines for cancer treatments

Liu, Z., Ma, P., & Lin, J. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.217230 · Cited by 13

Bidirectionally H2O2-suppliable and antioxidant-consumable copper peroxide nanoparticles for photochemodynamic immunotherapy

Zhao, Y., Li, T., Yao, Y., Xue, S., Xu, T., Mi, S., Li, D., Tang, X., Zhi, F., Ding, D., et al. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.123988 · Cited by 13

Biomimetic cascade “four-in-one” Nanozyme for remodeling the redox tumor microenvironment and disrupting energy homeostasis to enhance ferroptosis against triple-negative breast cancer

Li, L., Liu, A., Wang, Z., Liang, H., Whittake, A. K., Guo, H., & Lin, Q. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124001 · Cited by 13

Advances in Fenton reaction-mediated ferroptosis for enhanced cancer therapy: mechanisms, amplification strategies, and synergistic approaches

Huang, Q., Ma, C., Wei, P., Wang, Q., Ren, H., & Li, X. (2026) · Journal of Materials Chemistry B · doi:10.1039/d5tb02738a · Cited by 13

Bioinformatics and Network Pharmacology of the First Crystal Structured Clerodin: Anticancer and Antioxidant Potential against Human Breast Carcinoma Cell

Pakrashy, S., Mandal, P. K., Goswami, J. N., Dey, S. K., Choudhury, S. M., Bhattacharya, B., Emmerling, F., Alasmary, F. A., & Dolai, M. (2022) · ACS Omega · doi:10.1021/acsomega.2c07173 · Cited by 15

Ultrasensitive photoelectrochemical detection of glutathione based on the multifunctional catalytic properties of phosphotungstic acid

Jiang, Y., Zhang, H., Xu, M., Luo, F., Lin, C., Qiu, B., Lin, Z., Zhou, J., & Wang, J. (2023) · The Analyst · doi:10.1039/d3an00702b · Cited by 13

Engineering of a GSH activatable photosensitizer for enhanced photodynamic therapy through disrupting redox homeostasis

Fu, D., Wang, Y., Kaiwen, L., Huang, L., Xu, J., & Wu, H. (2023) · RSC Advances · doi:10.1039/d3ra04074g · Cited by 13

Biotin-Functionalized Iridium-Based Nanoparticles as Tumor Targeted Photosensitizers for Enhanced Oxidative Damage in Tumor Photodynamic Therapy

Wei, L., He, X., Liu, C., Kandawa-Shultz, M., Shao, G., & Wang, Y. (2023) · ACS Applied Nano Materials · doi:10.1021/acsanm.3c05145 · Cited by 14

MRI-visualized PTT/CDT for breast cancer ablation and distant metastasis prevention

Xu, Q., Ban, X., Yang, L., Chen, Y., Zhang, F., Wang, Y., Cao, P., Yu, M., & Duan, X. (2024) · Applied Materials Today · doi:10.1016/j.apmt.2024.102059 · Cited by 13

A Chemo/photo-responsive immunomodulatory nanoplatform for treatment of multidrug-resistant bacterial sepsis

Yao, W., Liu, T., Wang, Y., Yuan, Y., Yuan, Y., Liu, L., Guo, Z., Ye, J., Liu, X., Wang, X., et al. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.150124 · Cited by 13

NIR Light‐Fuse Drug‐Free Photothermal Armor‐Piercing Microcapsule for Femoral Vein Thrombosis Therapy

Yang, N., Qian, Z., Yuan, R., Li, W., Tan, X., Liu, Z., Zhang, Q., Ge, L., & Liu, L. (2024) · Small · doi:10.1002/smll.202312191 · Cited by 13

Exposure to resorcinol bis (diphenyl phosphate) induces colonization of alien microorganisms with potential impacts on the gut microbiota and metabolic disruption in male zebrafish

Wang, X., Lu, T., Yang, B., Cao, J., & Li, M. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.172892 · Cited by 13

Therapeutic potentials of FexMoyS-PEG nanoparticles in colorectal cancer: a multimodal approach via ROS-ferroptosis-glycolysis regulation

Yu, Z., Wang, C., Ye, Y., Wang, S., & Jiang, K. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02515-3 · Cited by 13

A multifunctional nanoplatform for chemotherapy and nanocatalytic synergistic cancer therapy achieved by amplified lipid peroxidation

Zhuge, X., Tang, R., Jiang, Y., Lin, L., Xi, D., & Yang, H. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.06.029 · Cited by 13

Engineering Magnetic Extracellular Vesicles Mimetics for Enhanced Targeting Chemodynamic Therapy to Overcome Ovary Cancer

Wang, S., Mao, Y., Rong, S., Liu, G., Cao, Y., Yang, Z. Y., Yu, H., Zhang, X., Fang, H., Cai, Z., et al. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c06862 · Cited by 13

Zwitterionic-hydrogel-based sensing system enables real-time ROS monitoring for ultra-long hypothermic cell preservation

Tian, Y., Ma, Y., Kang, Y., Tian, S., Li, Q., Zhang, L., & Yang, J. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.07.043 · Cited by 13

Investigating the mechanism of ferroptosis induction by sappanone A in hepatocellular carcinoma: NRF2/xCT/GPX4 axis

Xing, Y., Yang, H., Dai, C.-L., Qiu, Z., Guan, Y., & Zhang, L. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176965 · Cited by 13

Deferiprone protects photoreceptors by inhibiting ferroptosis after experimental retinal detachment

Ye, Z., Yan, Y., Jin, F., Jiang, J., Deng, C., Wang, L., & Dong, K. (2024) · Experimental Eye Research · doi:10.1016/j.exer.2024.110156 · Cited by 13

A minimalist multifunctional nano-prodrug for drug resistance reverse and integration with PD-L1 mAb for enhanced immunotherapy of hepatocellular carcinoma

Zou, T., Huang, Y., Zhou, Z., He, S., Liu, J., Chen, Y., Liu, H., Luo, Z. K., Liu, M., Wei, H., et al. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-03027-w · Cited by 13

Chemotherapeutic hormesis induced by the tumor microenvironment in refractory ovarian cancer

Chang, X., Tamauchi, S., Nakagawa, A., Xinyuan, W., Yoshida, K., Yokoi, A., Yoshikawa, N., & Kajiyama, H. (2025) · Scientific Reports · doi:10.1038/s41598-024-84290-7 · Cited by 13

Baicalin restores dopamine homeostasis in the ADHD model by regulating DAT-VMAT2 transport imbalance through activation of the Nrf2/Keap-1/HO-1 pathway

Ding, X., Ma, B., Zhou, R., Zhang, Y., Zhang, Y., Xie, X., Wang, M., Wu, C., & Jia, J. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.02.032 · Cited by 14

“Dual lock-and-key” triggered and endoplasmic reticulum targeting nanophotosensitizers for activatable Type-I photodynamic and photothermal therapies

Zhan, R., Zhou, W., Ma, H., Zou, M., Zhang, M., Zhang, W., & Tian, J. H. (2025) · Chemical Science · doi:10.1039/d5sc01987g · Cited by 13

Integrative single-cell and spatial transcriptomics uncover ELK4-mediated mechanisms in NDUFAB1+ tumor cells driving gastric cancer progression, metabolic reprogramming, and immune evasion

Sun, Y., Nie, W., Xiahou, Z., Wang, X., Liu, W., Liu, Z., Lin, Z., & Zd, L. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1591123 · Cited by 13

Effective Genome Editing Using CRISPR‐Cas9 Nanoflowers

Zhang, C., Ren, H., Liu, G., Li, J., Wang, X., & Zhang, Y. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202102365 · Cited by 13

A carrier free photodynamic oxidizer for enhanced tumor therapy by redox homeostasis disruption

Ni, Y., Zheng, R., Chen, Z., Wang, R.-X., Zhao, L., Chen, X., Chen, L., Xu, L., Li, S., & Chen, A. (2022) · Biomaterials Science · doi:10.1039/d1bm01876k · Cited by 13

Dual stimuli-responsive nanocarriers based on polyethylene glycol-mediated schiff base interactions for overcoming tumour chemoresistance

Wei, D., Tong, Q., An, Q., Ma, X., Jiang, X. L., Li, X., & Zeng, Y. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.112408 · Cited by 13

Tumor-targeted dual-starvation therapy based on redox-responsive micelle nanosystem with co-loaded LND and BPTES

Fu, Z., Du, H., Meng, S., Yao, M., Zhao, P., Li, X., Zheng, X., Zhang, Y., Yang, H., Cai, K., et al. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100449 · Cited by 13

Nanotherapeutics induced redox resetting of oxidative and nitrosative stress: targeting glutathione-depletion in cancer

Dangi, K., Kumar, V., Mittal, D., Yadav, P., Malik, M., & Verma, A. K. (2025) · Nanomedicine · doi:10.1080/17435889.2025.2489918 · Cited by 13

Engineering nanomedicine for glutathione depletion-augmented cancer therapy

Xiong, Y., Xiao, C., Li, Z., & Yang, X. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00718h · Cited by 702

Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy

Roy, N., & Paira, P. (2024) · ACS Omega · doi:10.1021/acsomega.3c08890 · Cited by 60

Harnessing ROS Amplification and GSH Depletion Using a Carrier‐Free Nanodrug to Enhance Ferroptosis‐Based Cancer Therapy

Zhang, H., Shan, G., Liu, M., Sun, Q., Yang, T., Peng, R., Li, X., Mei, Y., He, X., & Qiao, L. (2024) · Small · doi:10.1002/smll.202409250 · Cited by 33

Novel strategies of glutathione depletion in photodynamic and chemodynamic therapy: A review

Wolny, D., Stojko, M., & Zajdel, A. (2024) · Advances in Clinical and Experimental Medicine · doi:10.17219/acem/191025 · Cited by 11