Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management

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Glucagon-like peptide-1(GLP-1) Prevents Doxorubicin-Induced Cardiotoxicity by Regulating Macrophage PolarizationPreprint

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Molecular mechanisms of doxorubicin-induced cardiotoxicity based on mitochondrial function and traditional Chinese medicine treatment

Wang, X., Ling, G., WeiLi, L. I., Wei, W. A. N. G., & Wang, Y. (2022) · Scientia Sinica Vitae · doi:10.1360/ssv-2021-0406

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Can Exercise Training Prevent Doxorubicin-induced Cardiomyopathy?

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The possible protective role of Moringa Oleifera and Vitamin E on Doxorubicin-induced cardiotoxicity in adult albino rats:Histological and Immunohistochemical study

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Characterization and synthesis of mesoporous silica nanoparticles modified using Zn, NH2, and graphene oxide containing Doxorubicin and assessment of its apoptosis induction, cytotoxicity, and anti-metastatic effects on MDA-MB-231 cell linePreprint

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Uterine effects of Chemotherapy and Preventive Methods

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The Effect of Oral Andrographolide on Cardiac Biomarkers in Doxorubicin-induced Rats

Hanifah, S., Arozal, W., & Juniantito, V. (2023) · Journal Of Medicine & Health · doi:10.28932/jmh.v5i2.5026

Cardiotoxicity of Chemotherapy in Lynch Syndrome – A Literature Review

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Poncirus trifoliata Aqueous Extract Protects Cardiomyocytes against Doxorubicin-Induced Toxicity through Upregulation of NAD(P)H Dehydrogenase Quinone Acceptor Oxidoreductase 1

Kim, M., Choi, H., Park, S., Lee, J.-I., & Lee, J. (2023) · Molecules · doi:10.3390/molecules28248090

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Sophora interrupta bedd., ameliorates doxorubicin induced myocardial necrosis by attenuation of oxidative stress and structural cardiomyocyte alterations in rats

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Cannabidiol Attenuates Doxorubicin-Related Cardiac Disorders Using Modulation of IL6R Signifying Trail in Adult Male Sprague Dawley RatsPreprint

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Sage (Salvia officinalis) alleviates trazadone induced rat cardiotoxicity mediated via modulation of autophagy and oxidative stress

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Anti-apoptotic effects of minocycline on doxorubicin-induced cardiotoxicity in male Wistar rats

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The cardioprotective properties of Persicaria maculosa and Citrus sinensis extracts against doxorubicin-induced cardiotoxicity in mice.

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Cannabidiol Attenuates Doxorubicin-Related Cardiac Disorders Using Modulation of IL6R Signifying Trail in Adult Male Sprague DawleyPreprint

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ROS Signaling Controls Lipid Accumulation in HepG2 Cells Driven by Doxorubicin-Induced Senescence

Yun, C., Noh, S. J., Zahrani, H. K., Kim, S. H., & Jung, Y. (2025) · Drug Targets and Therapeutics · doi:10.58502/dtt.24.0020

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Saravia, S. D., & Sahni, G. (2025) · Annals of Internal Medicine Clinical Cases · doi:10.7326/aimcc.2024.0576

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Co-medication effects of Doxorubicin and Bendamustine on DNA molecules ananlyized with a variety of single-molecule spectroscopy

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Xiao, S., Li, Y. R., Li, B., Wang, H., Wang, K., & Yang, S. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s526611

Integrating Microarray Analysis, Machine Learning, and Molecular Docking to Explore the Mechanism of Doxorubicin-induced Cardiotoxicity

Zhu, Y., He, J., & Wei, R. (2025) · Current Medicinal Chemistry · doi:10.2174/0109298673401752250709101602

Development of sublingual melatonin nanofibers in enhancing the anticancer effects of doxorubicin, in vitro and in vivo studies

Shahgordi, S., Nosratzadeh, N., Kaffash, E., Dehestani, S., Ansari, B., Marouzi, S., Abbaspour, M., & Hashemi, M. (2025) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2025.107304

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Tarannum, M., Goel, R., & Kumar, R. (2025) · International Journal of Newgen Research in Pharmacy & Healthcare · doi:10.61554/ijnrph.v3i1.2025.146

Doxorubicin-Induced Cardiotoxicity at Non-Cumulative Dose in a Dog with Multicentric Lymphoma

Go, J., Ahn, S., Heo, S., Hwang, S., Ryu, H., Park, J., Shin, C., Jung, D., Yu, D., & Bae, H. (2025) · Journal of Veterinary Clinics · doi:10.17555/jvc.2025.42.4.190

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Демянчук, Н., & Пазюк, Л. (2025) · Перспективи та інновації науки · doi:10.52058/2786-4952-2025-8(54)-2123-2138

Correlation Between Blood Transforming Growth Factor-Beta 1 (TGF-β1) Levels and Cardiac Function Parameters Following Doxorubicin Chemotherapy

Yazid, M., Lnu, M., Koesnoe, S., Rinaldi, I., Winston, K., & Putra, D. (2025) · Cureus · doi:10.7759/cureus.91632

Nontraditional Models for Acute Kidney Injury Research: Organoids, Zebrafish, and More

Jog, E., Wu, T., Maggiore, J. C., & Hukriede, N. A. (2025) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2025.151668

Engineering a bi-functional nanoplatform containing FH peptide for preferential cardiac delivery to counteract doxorubicin-induced cardiotoxicity

Li, J., Zhong, Z.-L., Tang, J. Y., Chen, Y., Xiang, C.-P., Li, J., Tian, J., Luo, X., Jian-jie, Z., & Tian, Y. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-08617-w

Pharmacotherapies in Prevention of Myocardial Oxidative Stress Mediated by Anthracyclines, Taxanes, and Alkylating Agents

Osuji, E., Wright, J. L., Brar, T., Scott, S. S., & Smith, S. A. (2025) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-3-031-97517-2_6

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Scott, S. S., Albers, C., Iqbal, M., Ailemen, I., Smith, S. A., & Parinandi, N. L. (2025) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-3-031-97517-2_4

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Bhullar, S. K., Thingnam, R., Rabinovich-Nikitin, I., & Kirshenbaum, L. A. (2025) · Advances in biochemistry in health and disease · doi:10.1007/978-3-031-90598-8_17

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Dohadwala, T. K., Abbas, R. H., Siji, S. M., Nadar, S., Sakina, S., Jairath, N., Patel, H. A., & Zurashvili, T. (2025) · Discoveries · doi:10.15190/d.2025.15

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Additional file 1 of Momordica charantia L.-derived exosome-like nanovesicles stabilize p62 expression to ameliorate doxorubicin cardiotoxicity

Ye, C., Yan, C., Bian, S., Li, X.-R., Li, Y., Wang, K.-X., Zhu, Y.-H., Wang, L., Wang, Y.-C., Wang, Y.-Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26488302

Additional file 1 of Liguzinediol potentiates the metabolic remodeling by activating the AMPK/SIRT3 pathway and represses Caspase-3/GSDME-mediated pyroptosis to ameliorate cardiotoxicity

Zhu, W., Lian, N., Wang, J., Zhao, F., Liu, B., Sheng, J., Zhang, C., Zhou, X., Wenbai, G., Xie, C., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26043670

Additional file 1 of [123I]MIBG is a better early marker of anthracycline cardiotoxicity than [18F]FDG: a preclinical SPECT/CT and simultaneous PET/MR study

Oudot, A., Courteau, A., Guillemin, M., Vrigneaud, J., WALKER, P. M., Brunotte, F., Cochet, A., & Collin, B. (2021) · Figshare · doi:10.6084/m9.figshare.16649975

Additional file 1 of Soluble urokinase plasminogen activator receptor and cardiotoxicity in doxorubicin-treated breast cancer patients: a prospective exploratory study

Chu, J., Tung, L., Attalah, I., Wei, C., Cobleigh, M., Rao, R. D., Feinstein, S. B., Usha, L., Banach, K., Reiser, J., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25001686

Additional file 1 of Cardioprotective effect of crude polysaccharide fermented by Trametes Sanguinea Lyoyd on doxorubicin-induced myocardial injury mice

Shen, C., Yang, B., Huang, L., Chen, Y., Zhao, H., & Zhu, Z. (2023) · Figshare · doi:10.6084/m9.figshare.22600799

Additional file 1 of Doxorubicin-loaded polymeric nanoparticles containing ketoester-based block and cholesterol moiety as specific vehicles to fight estrogen-dependent breast cancer

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Additional file 1 of Bento: a toolkit for subcellular analysis of spatial transcriptomics data

Mah, C. K., Ahmed, N., Lopez, N. A., Lam, D. C., Pong, A., Monell, A., Kern, C., Han, Y., Prasad, G., Cesnik, A. J., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25530351

Additional file 2 of Bento: a toolkit for subcellular analysis of spatial transcriptomics data

Mah, C. K., Ahmed, N., Lopez, N. A., Lam, D. C., Pong, A., Monell, A., Kern, C., Han, Y., Prasad, G., Cesnik, A. J., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25530473

Biomarkers for Early Detection of Doxorubicin-Induced Cardiotoxicity: A Focus on miRNAs and EXOs

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AI-Driven Risk Stratification in Cardiology: Predicting Cardiovascular Outcomes, Sudden Cardiac Death, Cardiotoxicity, and Heart Failure with CMR

Jolfayi, A. G., Montazeri, S., Poopak, A., Soheili, A., Tavakoli, A. M., Salmanipour, A., Adimi, S., & Rezaei-Kalantari, K. (2025) · Springer eBooks · doi:10.1007/978-981-95-0313-1_8

The Cardioprotective Effects Of Bromelain On Wistar Rat Myocardial Cells Induced By Doxorubicin: An Evaluation Based On Troponin T And Troponin I

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Nanomedicine-Based Strategies for Mitigating Chemo/Radiotherapy-Induced Cardiac Inflammation and Fibrosis

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Cardioprotective Effects of Bromelain on Wistar Rat (Rattus norvegicus) Cardiomyocytes Exposed to Doxorubicin

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Doxorubicin-induced phosphorylation of lamin A/C enhances DNMT1 and activates cardiomyocyte death via suppressing GATA-4 and Bcl-xL in rat heart

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Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity

Ferreira, A., Cunha‐Oliveira, T., Simões, R. F., Carvalho, F. S., Burgeiro, A., Nordgren, K. K. S., Wallace, K. B., & Oliveira, P. J. (2017) · Toxicology · doi:10.1016/j.tox.2017.08.011 · Cited by 78

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Mitigation of doxorubicin-induced cardiotoxicity by dichloroacetate: potential roles of restoration of PGC-1α/SIRT3 signaling and suppression of oxidative stress and apoptosis.

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