The Role of DNA Copy Number Variation in Schizophrenia

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

The International Schizophrenia Consortium (2009) · Nature · doi:10.1038/nature08185 · Cited by 4,821 · see citing works

Strong association of de novo copy number mutations with autism

Sebat, J., Lakshmi, B., Malhotra, D., Troge, J., Lese-Martin, C., Walsh, T., Yamrom, B., Yoon, S., Krasnitz, A., Kendall, J., et al. (2007) · Science · doi:10.1126/science.1138659 · Cited by 2,795 · see citing works

22q11.2 deletion syndrome

McDonald-McGinn, D. M., Sullivan, K. E., Marino, B., Philip, N., Swillen, A., Vorstman, J. A. S., Zackai, E. H., Emanuel, B. S., Vermeesch, J. R., Morrow, B. E., et al. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.71 · Cited by 2,236 · see citing works

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

Lohmueller, K. E., Pearce, C. L., Pike, M., Lander, E. S., & Hirschhorn, J. N. (2003) · Nature Genetics · doi:10.1038/ng1071 · Cited by 1,900 · see citing works

Structural Variation of Chromosomes in Autism Spectrum Disorder

Marshall, C. R., Noor, A., Vincent, J. B., Lionel, A. C., Feuk, L., Skaug, J., Shago, M., Moessner, R., Pinto, D., Ren, Y., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.12.009 · Cited by 1,815 · see citing works

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

Walsh, T., McClellan, J. M., McCarthy, S. E., Addington, A. M., Pierce, S. B., Cooper, G. M., Nord, A. S., Kusenda, M., Malhotra, D., Bhandari, A., et al. (2008) · Science · doi:10.1126/science.1155174 · Cited by 1,800 · see citing works

Large recurrent microdeletions associated with schizophrenia.

GROUP, Stefansson, H., Rujescu, D., Cichon, S., Pietiläinen, O. P. H., Ingason, A., Steinberg, S., Fossdal, R., Sigurdsson, E., Sigmundsson, T., et al. (2008) · Nature · doi:10.1038/nature07229 · Cited by 1,745 · see citing works

Common variants conferring risk of schizophrenia

†Genetic Risk and Outcome in Psychosis (GROUP), Stefansson, H., Ophoff, R. A., Steinberg, S., Andreassen, O. A., Cichon, S., Rujescu, D., Werge, T., Pietiläinen, O. P. H., Mors, O., et al. (2009) · Nature · doi:10.1038/nature08186 · Cited by 1,677 · see citing works

Rare chromosomal deletions and duplications increase risk of schizophrenia

The International Schizophrenia Consortium (2008) · Nature · doi:10.1038/nature07239 · Cited by 1,475 · see citing works

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

The Autism Genome Project Consortium (2007) · Nature Genetics · doi:10.1038/ng1985 · Cited by 1,402 · see citing works

Disruption of two novel genes by a translocation co-segregating with schizophrenia

Millar, J. K. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.9.1415 · Cited by 1,254 · see citing works

Are Rare Variants Responsible for Susceptibility to Complex Diseases?

Pritchard, J. K. (2001) · The American Journal of Human Genetics · doi:10.1086/321272 · Cited by 1,197 · see citing works

Proteomic analysis of NMDA receptor–adhesion protein signaling complexes

Husi, H., Ward, M. A., Choudhary, J. S., Blackstock, W. P., & Grant, S. G. N. (2000) · Nature Neuroscience · doi:10.1038/76615 · Cited by 1,194 · see citing works

Common variants on chromosome 6p22.1 are associated with schizophrenia

Shi, J., Levinson, D. F., Duan, J., Sanders, A. R., Zheng, Y., Pe’er, I., Dudbridge, F., Holmans, P., Whittemore, A. S., Mowry, B. J., et al. (2009) · Nature · doi:10.1038/nature08192 · Cited by 1,154 · see citing works

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

Freedman, R., Coon, H., Myles-Worsley, M., Orr-Urtreger, A., Olincy, A., Davis, A., Polymeropoulos, M., Holik, J., Hopkins, J., Hoff, M., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.2.587 · Cited by 1,141 · see citing works

Identification of loci associated with schizophrenia by genome-wide association and follow-up

Molecular Genetics of Schizophrenia Collaboration, O'Donovan, M. C., Craddock, N., Norton, N., Williams, H., Peirce, T., Moskvina, V., Nikolov, I., Hamshere, M., Carroll, L., et al. (2008) · Nature Genetics · doi:10.1038/ng.201 · Cited by 1,070 · see citing works

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

Mei, L., & Xiong, W.-C. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2392 · Cited by 1,030 · see citing works

High rates of schizophrenia in adults with velo-cardio-facial syndrome

Murphy, K. C., Jones, L. A., & Owen, M. J. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.10.940 · Cited by 1,024 · see citing works

Segmental Duplications and Copy-Number Variation in the Human Genome

Sharp, A. J., Locke, D. P., McGrath, S. D., Cheng, Z., Bailey, J. A., Vallente, R. U., Pertz, L. M., Clark, R. A., Schwartz, S., Segraves, R., et al. (2005) · The American Journal of Human Genetics · doi:10.1086/431652 · Cited by 973 · see citing works

Strong association of de novo copy number mutations with sporadic schizophrenia

Xu, B., Roos, J. L., Levy, S., van Rensburg, E. J., Gogos, J. A., & Karayiorgou, M. (2008) · Nature Genetics · doi:10.1038/ng.162 · Cited by 813 · see citing works

Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes

Mefford, H. C., Sharp, A. J., Baker, C., Itsara, A., Jiang, Z., Buysse, K., Huang, S., Maloney, V. K., Crolla, J. A., Baralle, D., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0805384 · Cited by 804 · see citing works

Schizophrenia and Affective Disorders—Cosegregation with a Translocation at Chromosome 1q42 That Directly Disrupts Brain-Expressed Genes: Clinical and P300 Findings in a Family

Blackwood, D., Fordyce, A., Walker, M. T., Clair, D. M. S., Porteous, D. J., & Muir, W. J. (2001) · The American Journal of Human Genetics · doi:10.1086/321969 · Cited by 734 · see citing works

Association within a family of a balanced autosomal translocation with major mental illness

St Clair, D., Blackwood, D., Muir, W., Walker, M., St Clair, D., Muir, W., Carothers, A., Spowart, G., Gosden, C., & Evans, H. J. (1990) · The Lancet · doi:10.1016/0140-6736(90)91520-k · Cited by 727 · see citing works

The allelic architecture of human disease genes: common disease-common variant... or not?

Pritchard, J. K. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.20.2417 · Cited by 711 · see citing works

Copy-number variations associated with neuropsychiatric conditions

Cook Jr, E. H., & Scherer, S. W. (2008) · Nature · doi:10.1038/nature07458 · Cited by 659 · see citing works

DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling

Millar, J. K., Pickard, B. S., Mackie, S., James, R., Christie, S., Buchanan, S. R., Malloy, M. P., Chubb, J. E., Huston, E., Baillie, G. S., et al. (2005) · Science · doi:10.1126/science.1112915 · Cited by 648 · see citing works

Neurexin–neuroligin signaling in synapse development

Craig, A. M., & Kang, Y. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.01.011 · Cited by 640 · see citing works

Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11.

Karayiorgou, M., Morris, M. A., Morrow, B., Shprintzen, R. J., Goldberg, R., Borrow, J., Gos, A., Nestadt, G., Wolyniec, P. S., & Lasseter, V. K. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.17.7612 · Cited by 628 · see citing works

Copy-number variation and association studies of human disease

McCarroll, S. A., & Altshuler, D. M. (2007) · Nature Genetics · doi:10.1038/ng2080 · Cited by 622 · see citing works

Neurexin mediates the assembly of presynaptic terminals

Dean, C., Scholl, F. G., Choih, J., DeMaria, S., Berger, J., Isacoff, E., & Scheiffele, P. (2003) · Nature Neuroscience · doi:10.1038/nn1074 · Cited by 617 · see citing works

The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP

Napoli, I., Mercaldo, V., Boyl, P. P., Eleuteri, B., Zalfa, F., De Rubeis, S., Di Marino, D., Mohr, E., Massimi, M., Falconi, M., et al. (2008) · Cell · doi:10.1016/j.cell.2008.07.031 · Cited by 609 · see citing works

A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures.

Sharp, A. J., Mefford, H. C., Li, K., Baker, C., Skinner, C., Stevenson, R. E., Schroer, R. J., Novara, F., De Gregori, M., Ciccone, R., et al. (2008) · Nature Genetics · doi:10.1038/ng.93 · Cited by 582 · see citing works

Disruption of neurexin 1 associated with autism spectrum disorder

Kim, H.-G., Kishikawa, S., Higgins, A. W., Seong, I.-S., Donovan, D. J., Shen, Y., Lally, E., Weiss, L. A., Najm, J., Kutsche, K., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.09.011 · Cited by 578 · see citing works

The DISC locus in psychiatric illness

Chubb, J. E., Bradshaw, N. J., Soares, D. C., Porteous, D. J., & Millar, J. K. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002106 · Cited by 542 · see citing works

Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels.

Poliak, S., Gollan, L., Martinez, R., Custer, A., Einheber, S., Salzer, J., Trimmer, J., Shrager, P., & Peles, E. (1999) · Neuron · doi:10.1016/s0896-6273(00)81049-1 · Cited by 530 · see citing works

Behavioral phenotypes of Disc1 missense mutations in mice

Clapcote, S. J., Lipina, T. V., Millar, J. K., Mackie, S., Christie, S., Ogawa, F., Lerch, J. P., Trimble, K., Uchiyama, M., Sakuraba, Y., et al. (2007) · Neuron · doi:10.1016/j.neuron.2007.04.015 · Cited by 526 · see citing works

Psychiatric genetics: progress amid controversy

Burmeister, M., McInnis, M. G., & Zöllner, S. K. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2381 · Cited by 522 · see citing works

PDZ Domain Proteins: Plug and Play!

Nourry, C., Grant, S. G. N., & Borg, J. (2003) · Science Signaling · doi:10.1126/stke.2003.179.re7 · Cited by 490 · see citing works

The Behavioral Phenotype in Fragile X: Symptoms of Autism in Very Young Children with Fragile X Syndrome, Idiopathic Autism, and Other Developmental Disorders

Rogers, S. J., Wehner, E. A., & Hagerman, R. J. (2001) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200112000-00008 · Cited by 487 · see citing works

Disruption of the neurexin 1 gene is associated with schizophrenia

Rujescu, D., Ingason, A., Cichon, S., Pietiläinen, O. P. H., Barnes, M. R., Toulopoulou, T., Picchioni, M., Vassos, E., Ettinger, U., Bramon, E., et al. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddn351 · Cited by 471 · see citing works

A common molecular basis for rearrangement disorders on chromosome 22q11

Edelmann, L. J. (1999) · Human Molecular Genetics · doi:10.1093/hmg/8.7.1157 · Cited by 452 · see citing works

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome

Collins, M., Husi, H., Yu, L., Brandon, J. M., Anderson, C. N. G., Blackstock, W., Choudhary, J., & Grant, S. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03507.x · Cited by 448 · see citing works

Disrupted in Schizophrenia 1 (DISC1): Association with Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder

Hodgkinson, C. A., Goldman, D. A., Jaeger, J., Persaud, S. D., Kane, J. M., Lipsky, R. H., & Malhotra, A. K. (2004) · The American Journal of Human Genetics · doi:10.1086/425586 · Cited by 437 · see citing works

Genomic rearrangements and sporadic disease

Lupski, J. R. (2007) · Nature Genetics · doi:10.1038/ng2084 · Cited by 424 · see citing works

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

Kirov, G., Gumus, D., Chen, W., Norton, N., Georgieva, L., Sari, M., O'Donovan, M. C., Erdogan, F., Owen, M. J., Ropers, H.-H., et al. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm323 · Cited by 377 · see citing works

A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability

Zalfa, F., Eleuteri, B., Dickson, K. S., Mercaldo, V., Rubeis, S. D., di Penta, A., Tabolacci, E., Chiurazzi, P., Neri, G., Grant, S. G. N., et al. (2007) · Nature Neuroscience · doi:10.1038/nn1893 · Cited by 364 · see citing works

The comorbidity of autism with the genomic disorders of chromosome 15q11.2-q13

Hogart, A., Wu, D., LaSalle, J. M., & Schanen, N. C. (2008) · Neurobiology of Disease · doi:10.1016/j.nbd.2008.08.011 · Cited by 354 · see citing works

Genomewide association for schizophrenia in the CATIE study: results of stage 1

Sullivan, P. F., Lin, D. Y., Tzeng, J., van den Oord, E. J. C. G., Perkins, D. O., Stroup, T. S., Wagner, M. J., Lee, S., Wright, F. A., Zou, F., et al. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.25 · Cited by 354 · see citing works

Symptoms, signs, and diagnosis of schizophrenia

Andreasen, N. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91325-4 · Cited by 344 · see citing works

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia

Pletnikov, M. V., Ayhan, Y., Nikolskaia, O. V., Xu, Y., Ovanesov, M. V., Huang, H., Mori, S., Moran, T. H., & Ross, C. A. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002079 · Cited by 339 · see citing works

Oligonucleotide Microarray Analysis of Genomic Imbalance in Children with Mental Retardation

Friedman, J. M., Baross, Á., Delaney, A. D., Ally, A., Arbour, L. T., Asano, J. K., Bailey, D. K., Barber, S., Birch, P. H., Brown-John, M., et al. (2006) · The American Journal of Human Genetics · doi:10.1086/507471 · Cited by 325 · see citing works

The Genetics of Schizophrenia

Sullivan, P. F. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020212 · Cited by 324 · see citing works

Genetic variation at the 22q11 <i>PRODH2/DGCR6</i> locus presents an unusual pattern and increases susceptibility to schizophrenia

Liu, H., Heath, S. C., Sobin, C., Roos, J. L., Galke, B. L., Blundell, M. L., Lenane, M., Robertson, B., Wijsman, E. M., Rapoport, J. L., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.042700699 · Cited by 323 · see citing works

Chromosome 1 loci in Finnish schizophrenia families

Ekelund, J. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.15.1611 · Cited by 313 · see citing works

Schizophrenia: genes at last?

Owen, M. J., Craddock, N. J., & O’Donovan, M. C. (2005) · Trends in Genetics · doi:10.1016/j.tig.2005.06.011 · Cited by 308 · see citing works

Probing genetic overlap among complex human phenotypes

Rzhetsky, A., Wajngurt, D., Park, N., & Zheng, T. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704820104 · Cited by 298 · see citing works

CNTNAP2 gene dosage variation is associated with schizophrenia and epilepsy

Friedman, J. I., Vrijenhoek, T., Markx, S., Janssen, I. M., van der Vliet, W. A., Faas, B. H. W., Knoers, N. V. A. M., Cahn, W., Kahn, R. S., Edelmann, L. J., et al. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002049 · Cited by 297 · see citing works

Schizophrenia: a common disease caused by multiple rare alleles

McClellan, J. M., Susser, E., & King, M.-C. (2007) · British Journal of Psychiatry · doi:10.1192/bjp.bp.106.025585 · Cited by 296 · see citing works

Schizophrenia and velo-cardio-facial syndrome

Murphy, K. C. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07604-3 · Cited by 284 · see citing works

The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95

Todd, P. K., Mack, K. J., & Malter, J. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2336265100 · Cited by 280 · see citing works

The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses

Garcia, R. A. G., Vasudevan, K., & Buonanno, A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3596 · Cited by 278 · see citing works

Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia

Lencz, T., Morgan, T., Athanasiou, M., Dain, B., Reed, C. R., Kane, J. M., Kucherlapati, R., & Malhotra, A. K. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001983 · Cited by 278 · see citing works

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice

Koike, H., Arguello, P. A., Kvajo, M., Karayiorgou, M., & Gogos, J. A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511189103 · Cited by 276 · see citing works

Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways †

Nishimura, Y., Martin, C. L., Vazquez-Lopez, A., Spence, S. J., Alvarez-Retuerto, A. I., Sigman, M., Steindler, C., Pellegrini, S., Schanen, N. C., Warren, S. T., et al. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm116 · Cited by 276 · see citing works

Targeted tandem affinity purification of PSD‐95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins

Fernández, E., Collins, M. O., Uren, R. T., Kopanitsa, M. V., Komiyama, N. H., Croning, M. D. R., Zografos, L., Armstrong, J. D., Choudhary, J. S., & Grant, S. G. N. (2009) · Molecular Systems Biology · doi:10.1038/msb.2009.27 · Cited by 275 · see citing works

High frequency of neurexin 1β signal peptide structural variants in patients with autism

Feng, J., Schroer, R. J., Jin, Y., Song, W., Yang, C., Bockholt, A., Cook, E. H., Skinner, C. D., Schwartz, C. E., & Sommer, S. S. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.08.017 · Cited by 271 · see citing works

Recurrent CNVs Disrupt Three Candidate Genes in Schizophrenia Patients

Vrijenhoek, T., Buizer‐Voskamp, J. E., van der Stelt, I., Strengman, E., Sabatti, C., van Kessel, A. G., Brunner, H. G., Ophoff, R. A., & Veltman, J. A. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.09.011 · Cited by 265 · see citing works

Schizophrenia-Related Neural and Behavioral Phenotypes in Transgenic Mice Expressing TruncatedDisc1

Shen, S., Lang, B., Nakamoto, C., Zhang, F., Pu, J., Kuan, S. L., Chatzi, C. A., He, S., Mackie, I., Brandon, N. J., et al. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3299-08.2008 · Cited by 250 · see citing works

Mints as Adaptors

Biederer, T., & Südhof, T. C. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.c000656200 · Cited by 240 · see citing works

Autism spectrum disorders in Prader???Willi and Angelman syndromes: a systematic review

Veltman, M. W. M., Craig, E. E., & Bolton, P. (2005) · Psychiatric Genetics · doi:10.1097/00041444-200512000-00006 · Cited by 218 · see citing works

Autism Spectrum Disorders and Symptoms in Children with Molecularly Confirmed 22q11.2 Deletion Syndrome

Fine, S. E., Weissman, A., Gerdes, M., Pinto‐Martin, J. A., Zackai, E. H., McDonald‐McGinn, D. M., & Emanuel, B. S. (2005) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-005-5036-9 · Cited by 213 · see citing works

Molecular characterization of two proximal deletion breakpoint regions in both Prader-Willi and Angelman syndrome patients.

Christian, S. L., Robinson, W. P., Huang, B., Mutirangura, A., Line, M. R., Nakao, M., Surti, U., Chakravarti, A., & Ledbetter, D. H. (1995) · Europe PMC (PubMed Central) · Cited by 188 · see citing works

Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice

Lin, W., Sanchez, H. B., Deerinck, T. J., Morris, J. K., Ellisman, M. H., & Lee, K. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1299 · Cited by 188 · see citing works

Chromosome 22q11 deletion syndrome: Update and review of the clinical features, cognitive-behavioral spectrum, and psychiatric complications

Swillen, A., Vogels, A., Devriendt, K., & Fryns, J. P. (2000) · American Journal of Medical Genetics · doi:10.1002/1096-8628(200022)97:2 · Cited by 188 · see citing works

Autistic Spectrum Disorders in Velo-cardio Facial Syndrome (22q11.2 Deletion)

Antshel, K. M., Aneja, A., Strunge, L., Peebles, J., Fremont, W. P., Stallone, K., AbdulSabur, N., Higgins, A. M., Shprintzen, R. J., & Kates, W. R. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0308-6 · Cited by 183 · see citing works

A robust statistical method for case-control association testing with copy number variation

Barnes, C. P., Plagnol, V., Fitzgerald, T. W., Redon, R., Marchini, J., Clayton, D. G., & Hurles, M. E. (2008) · Nature Genetics · doi:10.1038/ng.206 · Cited by 176 · see citing works

Mutations in the DLG3 Gene Cause Nonsyndromic X-Linked Mental Retardation

Tarpey, P., Parnau, J., Blow, M., Woffendin, H., Bignell, G., Cox, C., Cox, J., Davies, H., Edkins, S., Holden, S., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/422703 · Cited by 176 · see citing works

DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder

Hennah, W., Thomson, P. A., McQuillin, A., Bass, N. J., Loukola, A., Anjorin, A., Blackwood, D., Curtis, D., Deary, I. J., Harris, S. E., et al. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.22 · Cited by 165 · see citing works

Neurexin 1α structural variants associated with autism

Jin, Y., Noltner, K., Feng, J., Li, W., Schroer, R. J., Skinner, C. D., Zeng, W., Schwartz, C. E., & Sommer, S. S. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.04.074 · Cited by 156 · see citing works

Velo-cardio-facial syndrome: a model for understanding the genetics and pathogenesis of schizophrenia

Murphy, K. C., & Owen, M. J. (2001) · The British Journal of Psychiatry · doi:10.1192/bjp.179.5.397 · Cited by 148 · see citing works

Evolutionarily conserved low copy repeats (LCRs) in 22q11 mediate deletions, duplications, translocations, and genomic instability: An update and literature review

Shaikh, T. H., Kurahashi, H., & Emanuel, B. S. (2001) · Genetics in Medicine · doi:10.1097/00125817-200101000-00003 · Cited by 147 · see citing works

High-resolution mapping of DNA copy alterations in human chromosome 22 using high-density tiling oligonucleotide arrays

Urban, A. E., Korbel, J. O., Selzer, R. R., Richmond, T., Hacker, A. M., Popescu, G. V., Cubells, J. F., Green, R., Emanuel, B. S., Gerstein, M., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511340103 · Cited by 138 · see citing works

A patient with vertebral, cognitive and behavioural abnormalities and a de novo deletion of NRXN1α

Zahir, F., Baross, Á., Delaney, A. D., Eydoux, P., Fernandes, N., Pugh, T. J., Marra, M. A., & Friedman, J. M. (2007) · Journal of Medical Genetics · doi:10.1136/jmg.2007.054437 · Cited by 132 · see citing works

The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour

Pocklington, A. J., Cumiskey, M. A., Armstrong, J. D., & Grant, S. G. N. (2006) · Molecular Systems Biology · doi:10.1038/msb4100041 · Cited by 130 · see citing works

The Role of Neuronal Complexes in Human X-Linked Brain Diseases

Laumonnier, F., Cuthbert, P. C., & Grant, S. G. N. (2007) · The American Journal of Human Genetics · doi:10.1086/511441 · Cited by 121 · see citing works

Chromosomal abnormalities and mental illness

MacIntyre, D. J., Blackwood, D., Porteous, D. J., Pickard, B. S., & Muir, W. J. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001232 · Cited by 107 · see citing works

Phenotypic and genetic complexity of psychosis

Craddock, N. J., O’Donovan, M. C., & Owen, M. J. (2007) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.106.033761 · Cited by 103 · see citing works

Mutational analysis of the neurexin/neuroligin complex reveals essential and regulatory components

Reißner, C., Klose, M., Fairless, R., & Missler, M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801639105 · Cited by 98 · see citing works

Autistic-like symptomatology in Prader-Willi syndrome: A review of recent findings

Dimitropoulos, A., & Schultz, R. T. (2007) · Current Psychiatry Reports · doi:10.1007/s11920-007-0086-7 · Cited by 95 · see citing works

Case–control study and transmission disequilibrium test provide consistent evidence for association between schizophrenia and genetic variation in the 22q11 gene ZDHHC8

Chen, W.-Y., Shi, Y., Zheng, Y., Zhao, X., Zhang, G., Chen, S.-Q., Yang, P.-D., & He, L. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh322 · Cited by 90 · see citing works

Reproductive fitness in familial schizophrenia

Bassett, A. S., Bury, A. S., Hodgkinson, K. A., & Honer, W. G. (1996) · Schizophrenia Research · doi:10.1016/0920-9964(96)00018-7 · Cited by 84 · see citing works

Detection of a novel familial deletion of four genes between BP1 and BP2 of the Prader-Willi/Angelman syndrome critical region by oligo-array CGH in a child with neurological disorder and speech impairment

Murthy, S. K., Nygren, A. O. H., El Shakankiry, H. M., Schouten, J. P., Al Khayat, A. I., Ridha, A., & Al Ali, M. T. (2007) · Cytogenetic and Genome Research · doi:10.1159/000097433 · Cited by 79 · see citing works

DISC1, PDE4B, and NDE1 at the centrosome and synapse

Bradshaw, N. J., Ogawa, F., Antolin‐Fontes, B., Chubb, J. E., Carlyle, B. C., Christie, S., Claessens, A., Porteous, D. J., & Millar, J. K. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.10.120 · Cited by 78 · see citing works

G2Cdb: the Genes to Cognition database

Croning, M. D. R., Marshall, M. C., McLaren, P., Armstrong, J. D., & Grant, S. G. N. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn700 · Cited by 75 · see citing works

Genomic disorders : the genomic basis of disease

Lupski, J. R., & Stankiewicz, P. (2006) · doi:10.1007/978-1-59745-039-3 · Cited by 72 · see citing works

Association study of polymorphisms in the 5′ upstream region of human DISC1 gene with schizophrenia

Kockelkorn, T. T. J. P., Arai, M., Matsumoto, H., Fukuda, N., Yamada, K., Minabe, Y., Toyota, T., Ujike, H., Sora, I., Mori, N., et al. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.06.048 · Cited by 70 · see citing works

Presynaptic Type III Neuregulin1-ErbB signaling targets α7 nicotinic acetylcholine receptors to axons

Hancock, M., Canetta, S., Role, L. W., & Talmage, D. A. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200710037 · Cited by 62 · see citing works

On the analysis of copy‐number variations in genome‐wide association studies: a translation of the family‐based association test

Ionita‐Laza, I., Perry, G. H., Raby, B. A., Klanderman, B. J., Lee, C., Laird, N. M., Weiss, S. T., & Lange, C. (2008) · Genetic Epidemiology · doi:10.1002/gepi.20302 · Cited by 59 · see citing works

Connexin 50 gene on human chromosome 1q21 is associated with schizophrenia in matched case–control and family-based studies

Ni, X., Valente, J., Azevedo, M. H., Pato, M. T., Pato, C. N., & Kennedy, J. L. (2007) · Journal of Medical Genetics · doi:10.1136/jmg.2006.047944 · Cited by 49 · see citing works

Schizophrenia: Genome, Interrupted

Cantor, R. M., & Geschwind, D. H. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.007 · Cited by 28 · see citing works

Dissecting DISC1 function through protein–protein interactions

Brandon, N. J. (2007) · Biochemical Society Transactions · doi:10.1042/bst0351283 · Cited by 28 · see citing works

Twin studies of schizophrenia: From bow-and-arrow concordances to Star Wars Mx and functional genomics

Cardno, A. G., & Gottesman, I. I. (2000) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(200021)97:1

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

Kirov, G., Pocklington, A. J., Holmans, P., Ivanov, D., Ikeda, M., Ruderfer, D., Moran, J., Chambert, K., Toncheva, D., Georgieva, L., et al. (2012) · Molecular Psychiatry · doi:10.1038/mp.2011.154 · Cited by 844 · see citing works

The Dynamics of DNA Methylation in Schizophrenia and Related Psychiatric Disorders

Grayson, D. R., & Guidotti, A. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.125 · Cited by 267 · see citing works

Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice

Doherty, J. L., & Owen, M. J. (2014) · Genome Medicine · doi:10.1186/gm546 · Cited by 228 · see citing works

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder

Casey, J. P., Magalhaes, T., Conroy, J. M., Regan, R., Shah, N., Anney, R., Shields, D. C., Abrahams, B. S., Almeida, J., Bacchelli, E., et al. (2012) · Human Genetics · doi:10.1007/s00439-011-1094-6 · Cited by 200 · see citing works

Single-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin Isoforms

Fuccillo, M. V., Földy, C., Gökçe, Ö., Rothwell, P. E., Sun, G. L., Malenka, R. C., & Südhof, T. C. (2015) · Neuron · doi:10.1016/j.neuron.2015.06.028 · Cited by 173 · see citing works

Human Spermatogenic Failure Purges Deleterious Mutation Load from the Autosomes and Both Sex Chromosomes, including the Gene DMRT1

Lopes, A. M., Aston, K. I., Thompson, E. E., Carvalho, F., Gonçalves, J., Huang, N., Matthiesen, R., Noordam, M. J., Quintela, I., Ramu, A., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003349 · Cited by 142 · see citing works

Confirmed rare copy number variants implicate novel genes in schizophrenia

Tam, G. W. C., van de Lagemaat, L. N., Redon, R., Strathdee, K. E., Croning, M. D. R., Malloy, M. P., Muir, W. J., Pickard, B. S., Deary, I. J., Blackwood, D. H. R., et al. (2010) · Biochemical Society Transactions · doi:10.1042/bst0380445 · Cited by 139 · see citing works

Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses

Dai, J., Aoto, J. N., & Südhof, T. C. (2019) · Neuron · doi:10.1016/j.neuron.2019.03.032 · Cited by 136 · see citing works

A comprehensive survey of copy number variation in 18 diverse pig populations and identification of candidate copy number variable genes associated with complex traits

Chen, C., Qiao, R., Wei, R., Guo, Y., Ai, H., Ma, J., Ren, J., & Huang, L. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-733 · Cited by 103 · see citing works

Revisiting the Relationship Between Autism and Schizophrenia: Toward an Integrated Neurobiology

de Lacy, N., & King, B. H. (2013) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050212-185627 · Cited by 98 · see citing works

A new paradigm emerges from the study of de novo mutations in the context of neurodevelopmental disease

Ku, C., Polychronakos, C., Tan, E., Naidoo, N., Yudi Pawitan, Y., Roukos, D. H., Mort, M. E., & Cooper, D. N. (2012) · Molecular Psychiatry · doi:10.1038/mp.2012.58 · Cited by 97 · see citing works

Hydroxyurea induces de novo copy number variants in human cells

Arlt, M. F., Ozdemir, A. C., Birkeland, S. R., Wilson, T. E., & Glover, T. W. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1109272108 · Cited by 95 · see citing works

Recent genomic advances in schizophrenia

Doherty, J. L., O’Donovan, M. C., & Owen, M. (2011) · Clinical Genetics · doi:10.1111/j.1399-0004.2011.01773.x · Cited by 93 · see citing works

The genomically mosaic brain: Aneuploidy and more in neural diversity and disease

Bushman, D. M., & Chun, J. J. M. (2013) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2013.02.003 · Cited by 93 · see citing works

Pathogenic or not? Assessing the clinical relevance of copy number variants

Hehir‐Kwa, J. Y., Pfundt, R., Veltman, J. A., & de Leeuw, N. (2013) · Clinical Genetics · doi:10.1111/cge.12242 · Cited by 93 · see citing works

Schizophrenia in a genomic era: a review from the pathogenesis, genetic and environmental etiology to diagnosis and treatment insights

Zamanpoor, M. (2019) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000245 · Cited by 91 · see citing works

New Copy Number Variations in Schizophrenia

Magri, C., Sacchetti, E., Traversa, M., Valsecchi, P., Gardella, R., Bonvicini, C., Minelli, A., Gennarelli, M., & Barlati, S. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013422 · Cited by 86 · see citing works

Genome-wide association studies of schizophrenia

Bergen, S. E., & Petryshen, T. L. (2012) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32835035dd · Cited by 85 · see citing works

RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia

Xu, J., Sun, J., Chen, J., Wang, L. H.-C., Li, A., Helm, M., Dubovsky, S. L., Bacanu, S., Zhao, Z., & Chen, X. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-s8-s2 · Cited by 77 · see citing works

Whole genome/exome sequencing in mood and psychotic disorders

Kato, T. (2014) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12247 · Cited by 70 · see citing works

Genome-wide analysis shows increased frequency of copy number variation deletions in Dutch schizophrenia patients

Buizer-Voskamp, J. E., Muntjewerff, J.-W., Strengman, E., Sabatti, C., Stefansson, H., Vorstman, J. A. S., & Ophoff, R. A. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.02.015 · Cited by 68 · see citing works

The DGCR5 long noncoding RNA may regulate expression of several schizophrenia-related genes

Meng, Q., Wang, K., Brunetti, T. M., Xia, Y., Jiao, C., Dai, R., Fitzgerald, D., Thomas, A. F., Jay, L., Eckart, H., et al. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aat6912 · Cited by 68 · see citing works

Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder

Kogan, J. H., Gross, A. K., Featherstone, R. E., Shin, R., Chen, Q., Heusner, C. L., Adachi, M., Lin, A., Walton, N. M., Miyoshi, S., et al. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.3967-14.2015 · Cited by 59 · see citing works

Implications of Genetic Findings for Understanding Schizophrenia

Owen, M. J. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs103 · Cited by 58 · see citing works

Rare CNVs and Tag SNPs at 15q11.2 are associated with schizophrenia in the Han Chinese population

Zhao, Q., Li, T., Zhao, X., Huang, K., Wang, T., Li, Z., Ji, J., Zeng, Z., Zhang, Z., Li, K., et al. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr197 · Cited by 58 · see citing works

De Novo CNV Formation in Mouse Embryonic Stem Cells Occurs in the Absence of Xrcc4-Dependent Nonhomologous End Joining

Arlt, M. F., Rajendran, S., Birkeland, S. R., Wilson, T. E., & Glover, T. W. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002981 · Cited by 54 · see citing works

Identification and characterization of three inherited genomic copy number variations associated with familial schizophrenia

Liao, H.-M., Chao, Y.-L., Huang, A.-L., Cheng, M.-C., Chen, Y.-J., Lee, K.-F., Fang, J., Hsu, C.-H., & Chen, C. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.05.015 · Cited by 53 · see citing works

Association of SNPs in EGR3 and ARC with Schizophrenia Supports a Biological Pathway for Schizophrenia Risk

Huentelman, M. J., Muppana, L., Corneveaux, J. J., Dinu, V., Pruzin, J. J., Reiman, R., Borish, C. N., De Both, M., Ahmed, A., Todorov, A., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0135076 · Cited by 52 · see citing works

Ethics and neuropsychiatric genetics: a review of major issues

Hoge, S. K., & Appelbaum, P. S. (2012) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145711001982 · Cited by 53 · see citing works

Family-based genome-wide copy number scan identifies five new genes of dyslexia involved in dendritic spinal plasticity

Veerappa, A. M., Saldanha, M., Padakannaya, P., & Ramachandra, N. B. (2013) · Journal of Human Genetics · doi:10.1038/jhg.2013.47 · Cited by 47 · see citing works

Germ cell mutagens: Risk assessment challenges in the 21st century

Singer, T. M., & Yauk, C. L. (2010) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20613 · Cited by 42 · see citing works

Progress in defining the biological causes of schizophrenia

Pickard, B. S. (2011) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399411001955 · Cited by 38 · see citing works

Next‐generation sequencing in schizophrenia and other neuropsychiatric disorders

Schreiber, M. A., Dorschner, M. O., & Tsuang, D. W. (2013) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32156 · Cited by 34 · see citing works

The X Files: “The Mystery of X Chromosome Instability in Alzheimer’s Disease”

Bajić, V., Essack, M., Živković, L., Stewart, A. J., Zafirovic, S. S., Bajić, V. B., Gojobori, T., Isenović, E. R., & Spremo‐Potparević, B. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2019.01368 · Cited by 33 · see citing works

Minor physical anomalies: potentially informative vestiges of fetal developmental disruptions in schizophrenia

Compton, M. T., Chan, R. C. K., Walker, E. F., & Buckley, P. F. (2010) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2010.10.006 · Cited by 31 · see citing works

Muscarinic Acetylcholine Receptor 3 Is Dominant in Myopia Progression

Lin, H.-J., Wan, L., Chen, W., Lin, J.-M., Lin, C.-J., & Tsai, F. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.11-9031 · Cited by 30 · see citing works

How genetic analysis may contribute to the understanding of avoidant/restrictive food intake disorder (ARFID)

Kennedy, H. L., Dinkler, L., Kennedy, M. A., Bulik, C. M., & Jordan, J. (2022) · Journal of Eating Disorders · doi:10.1186/s40337-022-00578-x · Cited by 29 · see citing works

Epigenetics and Biomarkers in the Staging of Neuropsychiatric Disorders

Archer, T., Beninger, R. J., Palomo, T., & Kostrzewa, R. M. (2010) · Neurotoxicity Research · doi:10.1007/s12640-010-9163-5 · Cited by 29 · see citing works

The Yin and Yang of nucleic acid-based therapy in the brain

Gustincich, S., Zucchelli, S., & Mallamaci, A. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.11.001 · Cited by 27 · see citing works

Heterogeneous contribution of microdeletions in the development of common generalised and focal epilepsies

Pérez‐Palma, E., Helbig, I., Klein, K. M., Anttila, V., Horn, H., Reinthaler, E. M., Gormley, P., Ganna, A., Byrnes, A., Pernhorst, K., et al. (2017) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2016-104495 · Cited by 26 · see citing works

Performance of copy number variants detection based on whole-genome sequencing by DNBSEQ platforms

Rao, J., Peng, L., Liang, X., Jiang, H., Geng, C., Zhao, X., Liu, X., Fan, G., Chen, F., & Mu, F. (2020) · BMC Bioinformatics · doi:10.1186/s12859-020-03859-x · Cited by 27 · see citing works

SNPranker 2.0: a gene-centric data mining tool for diseases associated SNP prioritization in GWAS

Ivan Merelli, A., Calabria, A., Cozzi, P., Viti, F., Mosca, E., & Milanesi, L. (2013) · BMC Bioinformatics · doi:10.1186/1471-2105-14-s1-s9 · Cited by 27 · see citing works

Converging levels of analysis on a genomic hotspot for psychosis: Insights from 22q11.2 Deletion Syndrome

Schreiner, M. J., Lázaro, M. T., Jalbrzikowski, M., & Bearden, C. E. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.09.012 · Cited by 27 · see citing works

Increased spontaneous gamma power and synchrony in schizophrenia patients having higher minor physical anomalies

Tikka, S. K., Nizamie, S. H., Das, B., Katshu, M. Z. U. H., & Goyal, N. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.09.006 · Cited by 27 · see citing works

New technologies provide insights into genetic basis of psychiatric disorders and explain their co-morbidity.

Rudan, I. (2010) · PubMed · Cited by 26 · see citing works

Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa

Simam, J., Rono, M. K., Ngoi, J. M., Nyonda, M. A., Mok, S., Marsh, K., Bozdech, Z., & Mackinnon, M. J. (2018) · BMC Genomics · doi:10.1186/s12864-018-4689-7 · Cited by 23 · see citing works

Hidden Markov Model-Based CNV Detection Algorithms for Illumina Genotyping Microarrays

Seiser, E., & Innocenti, F. (2014) · Cancer Informatics · doi:10.4137/cin.s16345 · Cited by 23 · see citing works

Comparison of Constitutional and Replication Stress-Induced Genome Structural Variation by SNP Array and Mate-Pair Sequencing

Arlt, M. F., Ozdemir, A. C., Birkeland, S. R., Lyons, R. H., Glover, T. W., & Wilson, T. E. (2011) · Genetics · doi:10.1534/genetics.110.124776 · Cited by 22 · see citing works

SVM 2 : an improved paired-end-based tool for the detection of small genomic structural variations using high-throughput single-genome resequencing data

Chiara, M., Pesole, G., & Horner, D. S. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks606 · Cited by 22 · see citing works

Evaluation of spontaneous dense array gamma oscillatory activity and minor physical anomalies as a composite neurodevelopmental endophenotype in schizophrenia

Tikka, S. K., Nizamie, S. H., Goyal, N., Pradhan, N., Tikka, D. L., & Katshu, M. Z. U. H. (2014) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2014.11.002 · Cited by 21 · see citing works

Psychiatrists’ Views of the Genetic Bases of Mental Disorders and Behavioral Traits and Their Use of Genetic Tests

Klitzman, R., Abbate, K., Chung, W. K., Marder, K. S., Ottman, R., Taber, K. J., Leu, C., & Appelbaum, P. S. (2014) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000154 · Cited by 21 · see citing works

Glutathione S-Transferase Deletion Polymorphisms in Early-Onset Psychotic and Bipolar Disorders: A Case-Control Study

Pejovic-Milovancevic, M. M., Mandić-Maravić, V., Coric, V. M., Mitković-Vončina, M., Kostic, M. V., Savic-Radojevic, A. R., Ercegovac, M., Matic, M. G., Peljto, A., Lečić‐Toševski, D., et al. (2016) · Laboratory Medicine · doi:10.1093/labmed/lmw017 · Cited by 19 · see citing works

Family-based association study of early growth response gene 3 with child bipolar I disorder

Gallitano, A. L., Tillman, R., Dinu, V., & Geller, B. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.01.011 · Cited by 19 · see citing works

Further investigation of the association between rs7341475 and rs17746501 and schizophrenia

Ben‐David, E., & Shifman, S. (2010) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.31093 · Cited by 18 · see citing works

An introduction to genes, genomes and disease

Hall, P. A., Reis-Filho, J. S., Tomlinson, I. P. M., & Poulsom, R. (2009) · The Journal of Pathology · doi:10.1002/path.2652 · Cited by 17 · see citing works

Genomic copy number variations: A breakthrough in our knowledge on schizophrenia etiology?

Hosák, L., Šilhán, P., & Hosáková, J. (2012) · PubMed · Cited by 16 · see citing works

Family based genome‐wide copy number scan identifies complex rearrangements at 17q21.31 in dyslexics

Veerappa, A. M., Saldanha, M., Padakannaya, P., & Ramachandra, N. B. (2014) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32260 · Cited by 16 · see citing works

A Pilot Study on Collective Effects of 22q13.31 Deletions on Gray Matter Concentration in Schizophrenia

Liu, J., Ulloa, A., Perrone‐Bizzozero, N. I., Yeo, R. A., Chen, J., & Calhoun, V. D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052865 · Cited by 15 · see citing works

Proteomic investigations of the synaptic vesicle interactome

Barth, J., & Volknandt, W. (2011) · Expert Review of Proteomics · doi:10.1586/epr.11.7 · Cited by 15 · see citing works

A case–control study and meta-analysis of association between a common copy number variation of the glutathione S-transferase mu 1 (GSTM1) gene and schizophrenia

Watanabe, Y., Nunokawa, A., Kaneko, N., & Someya, T. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.08.001 · Cited by 14 · see citing works

Copy Number Variants: A New Molecular Frontier in Clinical Psychiatry

Moreno‐De‐Luca, D., & Cubells, J. F. (2011) · Current Psychiatry Reports · doi:10.1007/s11920-011-0183-5 · Cited by 12 · see citing works

Long non-coding RNAs in schizophrenia: Genetic variations, treatment markers and potential targeted signaling pathways

Cao, T., Zhang, S., Chen, Q., Zeng, C., Wang, L., Jiao, S., Chen, H., Zhang, B., & Cai, H. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.07.027 · Cited by 11 · see citing works

Biomarker Identification Through Integrating fMRI and Epigenetics

Bai, Y., Zillé, P., Hu, W., Calhoun, V. D., & Wang, Y. (2019) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2019.2932895 · Cited by 11 · see citing works

Investigation of copy number variation in subjects with major depression based on whole-genome sequencing data

Yu, C., Baune, B. T., Wong, M., & Licinio, J. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.05.044 · Cited by 10 · see citing works

Neurobehavioral Dimensions of Prader Willi Syndrome: Relationships Between Sleep and Psychosis-Risk Symptoms

O’Hora, K., Zhang, Z., Vajdi, A., Kushan, L., Huang, Z. S., Pacheco-Hansen, L., Roof, E., Holland, A. J., Gur, R. C., & Bearden, C. E. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.868536 · Cited by 9 · see citing works

Zooming in on a gene

Piggins, H. D. (2011) · Nature · doi:10.1038/471455a · Cited by 8 · see citing works

Identifying Potential Regions of Copy Number Variation for Bipolar Disorder

Chen, Y., Lu, R., Hung, H., & Kuo, P. (2014) · Microarrays · doi:10.3390/microarrays3010052 · Cited by 8 · see citing works

The Genetics of Schizophrenia

Samson, J. N., & Wong, A. H. C. (2015) · Royal Society of Chemistry eBooks · doi:10.1039/9781782622499-00001 · Cited by 6 · see citing works

Pseudo‐heterozygous rearrangement mutation of parkin

Funayama, M., Yoshino, H., Li, Y., Kusaka, H., Tomiyama, H., & Hattori, N. (2012) · Movement Disorders · doi:10.1002/mds.24906 · Cited by 6 · see citing works

Genome-wide study of copy number variation implicates multiple novel loci for schizophrenia risk in Han Chinese family trios

Wu, X., Huai, C., Shen, L., Li, M., Yang, C., Zhang, J., Chen, L., Zhu, W., Fan, L., Zhou, W., et al. (2021) · iScience · doi:10.1016/j.isci.2021.102894 · Cited by 5 · see citing works

The psychosis risk timeline: can we improve our preventive strategies? Part 1: early life

Romain, K., Eriksson, A., Onyon, R., & Kumar, M. T. (2019) · BJPsych Advances · doi:10.1192/bja.2018.66 · Cited by 4 · see citing works

The Genetics of Schizophrenia

Walters, J., O’Donovan, M. C., & Owen, M. J. (2011) · Wiley eBooks · doi:10.1002/9780470978672.ch4 · Cited by 4 · see citing works

Restoring synaptic balance in schizophrenia: Insights from a thalamo-cortical conductance-based model

Berndt, L. C. S., Singh, K. D., & Shaw, A. D. (2026) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaf149 · Cited by 3 · see citing works

Neurodevelopmental Theories of Schizophrenia: Twenty‐First Century Perspectives

Haut, K. M., Schvarcz, A., Cannon, T. D., & Bearden, C. E. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy223 · Cited by 3 · see citing works

Genetische Aspekte der Neuropsychologie psychischer Störungen

Wagner, M. (2004) · Springer eBooks · doi:10.1007/978-3-662-08959-0_8 · Cited by 2 · see citing works

Schizophrenia in the Context of Neurodevelopmental Disorders in 16p12.2 Chromosomal Deletion: A Case Report

Uppinkudru, C., Basavaraju, R., Udupi, G. A., & Mehta, U. M. (2024) · Indian Journal of Psychological Medicine · doi:10.1177/02537176231222570 · Cited by 1 · see citing works

Genomic variants in an inbred mouse model predict mania-like behaviors

Saul, M. C., Stevenson, S. A., Zhao, C., Driessen, T. M., Eisinger, B. E., & Gammie, S. C. (2018) · PLoS ONE · doi:10.1371/journal.pone.0197624 · Cited by 1 · see citing works

Risperidone vs olanzapine in treatment of schizophrenia: a double blind clinical trial

Shafti, S. S., & Gilanipoor, M. (2018) · MOJ Addiction Medicine & Therapy · doi:10.15406/mojamt.2018.05.00095 · Cited by 1 · see citing works

Selected genetic polymorphisms of epidermal growth factor, dopamine-2 receptor, neuregulin-1 and inflammatory cytokines in schizophrenia

Hänninen, K. (2014) · Tampere University Institutional Repository (Tampere University) · Cited by 1 · see citing works

Neurobehavioral dimensions of Prader Willi Syndrome: Relationships between sleep disturbance and psychotic experiencesPreprint

Zhang, Z., Vajdi, A., Kushan, L., Huang, Z. S., Pacheco-Hansen, L., Roof, E., Holland, A. J., Port, A. M., Gur, R. C., & Bearden, C. E. (2020) · Research Square · doi:10.21203/rs.3.rs-131462/v1 · Cited by 1 · see citing works

Introduction

Cross, A. J. (2012) · doi:10.1002/9781118309421.ch · Cited by 1 · see citing works

Absolute quantification of gene copy number variation in Plasmodium falciparum novel putative genes associated to drug resistance (the actin-binding coronin protein, cysteine desulfurase and plasmepsin 2), using Eva green-based quantitative PCRPreprint

Diarra, H., Mobegi, V. A., Makhulu, E. E., Kinyua, J., & Herren, J. K. (2022) · Research Square · doi:10.21203/rs.3.rs-1451928/v1 · Cited by 1 · see citing works

Genomic copy number variation in schizophrenia

Rudd, D. S. (2014) · doi:10.17077/etd.ezs0wnfu

Tagging systems for sequencing large cohorts

Neiman, M. (2010) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

Association of copy number variation in Fc gamma receptor IIIb gene with risk of Graves' ophthalmopathy

Liao, W., Liu, Y.-H., Wan, L., Chang, C., Chen, C., Chen, Y., & Tsai, F. (2012) · ScienceAsia · doi:10.2306/scienceasia1513-1874.2012.38.256

Schizophrenia Has a High Heritability, but Where Are the Genes?

McDonald, P. P., & Singh, S. M. (2011) · Springer eBooks · doi:10.1007/978-94-007-0837-2_9

A stochastic inference of de novo CNV detection and association test in multiplex schizophrenia families

Wang, S., Chen, W. J., Tsai, Y.-C., Huang, Y.-H., Hwu, H., & Hsiao, C. K. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00185

A computational method for detecting multi-locus associations :an application to bipolar disorder

Mooney, M. A. (2014) · doi:10.6083/m4pc30cw

Comprehensive genetic association analysis of genes from the Reelin and DISC1 networks in schizophrenia and neurocognitive endophenotypes

Bouwer, S. (2010) · UWA Profiles and Research Repository (UWA)

Proteomics of Schizophrenia

Coba, M. P. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801829-3.00020-3

Identification and analysis of recently duplicated genes in channel catfish (Ictalurus punctatus) genome

Zhang, Y. (2013)

Heterogeneous Contribution of Microdeletions in the Development of Common Generalized and Focal epilepsiesPreprint

Pérez‐Palma, E., Helbig, I., Klein, K. M., Anttila, V., Horn, H., Reinthaler, E. M., Gormley, P., Ganna, A., Byrnes, A., Pernhorst, K., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/131359

Detecção precoce da deleção 22q11.2 em recém-nascidos e lactentes portadores de cardiopatia congênita

Grassi, M. S. (2020) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2020.tde-11032020-145355

Neurobehavioral dimensions of Prader Willi Syndrome: Relationships between sleep disturbance and psychotic experiencesPreprint

Zhang, Z., Vajdi, A., Kushan, L., Huang, Z. S., Pacheco-Hansen, L., Roof, E., Holland, A. J., Port, A. M., Gur, R. C., & Bearden, C. E. (2021) · Research Square · doi:10.21203/rs.3.rs-131462/v2

Introduction

Ebstein, R. P., Monakhov, M. V., Lai, P. S., & Shamay‐Tsoory, S. (2011) · Wiley eBooks · doi:10.1002/9781118101803.ch

Genetische Aspekte der Neuropsychologie psychischer Störungen

Wagner, M., & Petrovsky, N. (2010) · Springer eBooks · doi:10.1007/978-3-540-72340-0_8

Harnessing New Genomics Technologies to Assess Environmental Risk Factors That May Cause Heritable Genetic Disease

Beal, M. A. (2017) · doi:10.22215/etd/2017-11975

The impact of CNV burden on age at onset of schizophrenia

Muntané, G., Valle, A., Ramon-Cañellas, P., Martorell, L., & Vilella, E. (2026) · Schizophrenia Research · doi:10.1016/j.schres.2026.02.006

Copy number variants: a common mechanism in complex diseases

Estivill, X. (2008) · European Journal of Cancer Supplements · doi:10.1016/s1359-6349(08)71842-1

New Copy Number Variations in Schizophrenia

Magri, C., Sacchetti, E., Traversa, M., Valsecchi, P., Gardella, R., Bonvicini, C., Minelli, A., Gennarelli, M., & Barlati, S. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013422 · Cited by 86 · see citing works

Copy Number Variations in Schizophrenia: Critical Review and New Perspectives on Concepts of Genetics and Disease

Bassett, A. S., Scherer, S. W., & Brzustowicz, L. M. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09071016 · Cited by 201 · see citing works

Genomic copy number variations: A breakthrough in our knowledge on schizophrenia etiology?

Hosák, L., Šilhán, P., & Hosáková, J. (2012) · PubMed · Cited by 16 · see citing works

Copy Number Variations and Schizophrenia

Szecówka, K., Misiak, B., Łaczmańska, I., Frydecka, D., & Moustafa, A. A. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-03185-8 · Cited by 20 · see citing works