The one-two punch of alcoholism: role of central amygdala dynorphins/kappa-opioid receptors

The Rat Brain in Stereotaxic Coordinates

Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585 · see citing works

Guide for the Care and Use of Laboratory Animals: Eighth Edition

(2011) · doi:10.17226/12910 · Cited by 16,199 · see citing works

An opponent-process theory of motivation. I. Temporal dynamics of affect

Solomon, R. L., & Corbit, J. D. (1974) · Psychological Review · doi:10.1037/h0036128 · Cited by 1,704 · see citing works

The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991–1992 and 2001–2002

Grant, B. F., Dawson, D. A., Stinson, F. S., Chou, S. P., Dufour, M. C., & Pickering, R. P. (2004) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2004.02.004 · Cited by 1,509 · see citing works

New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: The striatopallidal, amygdaloid, and corticopetal components of substantia innominata

Alheid, G. F., & Heimer, L. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90217-5 · Cited by 1,217 · see citing works

Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

Chavkin, C., James, I. F., & D, A. G. M. (1982) · Science · doi:10.1126/science.6120570 · Cited by 1,171 · see citing works

Economic costs of excessive alcohol consumption in the U.S., 2006

Bouchery, E. E., Harwood, H. J., Sacks, J. J., Simon, C. J., & Brewer, R. D. (2011) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2011.06.045 · Cited by 1,041 · cited 4× · see citing works

Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain

Mansour, A., Khachaturian, H., Lewis, M. E. S., Akil, H., & Watson, S. J. (1988) · Pain · doi:10.1016/0304-3959(88)90103-0 · Cited by 973 · see citing works

Neurobiological similarities in depression and drug dependence: a self-medication hypothesis

Markou, A. (1998) · Neuropsychopharmacology · doi:10.1016/s0893-133x(97)00113-9 · Cited by 767 · see citing works

Multiple neural systems controlling food intake and body weight

Berthoud, H.-R. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(02)00014-3 · Cited by 725 · see citing works

Neurobiological mechanisms for opponent motivational processes in addiction

Koob, G. F., & Moal, M. L. (2008) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2008.0094 · Cited by 702 · see citing works

Chronic ethanol consumption:from neuroadaptation to neurodegeneration

Fadda, F. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00032-x · Cited by 564 · see citing works

Neuroimaging Abnormalities in the Amygdala in Mood Disorders

DREVETS, W. C. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07098.x · Cited by 544 · see citing works

A key role for corticotropin-releasing factor in alcohol dependence

Heilig, M., & Koob, G. F. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.06.006 · Cited by 503 · cited 1× · see citing works

Dynorphin, stress, and depression

Knoll, A. T., & Carlezon, W. A. (2010) · Brain Research · doi:10.1016/j.brainres.2009.09.074 · Cited by 465 · see citing works

An Opponent-Process Theory of Motivation

Solomon, R. L., & Corbit, J. D. (2008) · Cited by 461 · see citing works

Pharmacological evidence for a motivational role of κ-opioid systems in ethanol dependence

Walker, B. M., & Koob, G. F. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301438 · Cited by 392 · see citing works

Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking

Land, B. B., Bruchas, M. R., Schattauer, S., Giardino, W. J., Aita, M., Messinger, D., Hnasko, T. S., Palmiter, R. D., & Chavkin, C. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910705106 · Cited by 301 · see citing works

30 years of dynorphins — New insights on their functions in neuropsychiatric diseases

Schwarzer, C. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.05.006 · Cited by 290 · see citing works

Dynamics of Neuronal Circuits in Addiction: Reward, Antireward, and Emotional Memory

Koob, G. F. (2009) · Pharmacopsychiatry · doi:10.1055/s-0029-1216356 · Cited by 244 · see citing works

Systemic κ-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats

Walker, B. M., Zorrilla, E. P., & Koob, G. F. (2010) · Addiction Biology · doi:10.1111/j.1369-1600.2010.00226.x · Cited by 202 · see citing works

Association of the κ-opioid system with alcohol dependence

Xuei, X., Dick, D. M., Wetherill, L. F., Tian, H.-J., Arpana Agrawal, A., Bierut, L. J., Goate, A., Bucholz, K. K., Schuckit, M. A., Nürnberger, J. I., et al. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001882 · Cited by 177 · see citing works

Kappa receptor regulation of dopamine release from striatum and cortex of rats and guinea pigs.

Werling, L. L., Frattali, A. L., Portoghese, P. S., Takemori, A. E., & Cox, B. M. (1988) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)21016-3 · Cited by 177 · see citing works

Accelerated communciation: Constitutive μ opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence

Wang, Z. J., Bilsky, E. J., Porreca, F., & Sadée, W. (1994) · Life Sciences · doi:10.1016/0024-3205(94)90022-1 · Cited by 155 · see citing works

Differential effects of systemically administered nor-binaltorphimine (nor-BNI) on κ-opioid agonists in the mouse writhing assay

Broadbear, J. H., Negus, S. S., Butelman, E. R., de Costa, B. R., & Woods, J. H. (1994) · Psychopharmacology · doi:10.1007/bf02245071 · Cited by 139 · see citing works

κ-opioid receptors are implicated in the increased potency of intra-accumbens nalmefene in ethanol-dependent rats

Nealey, K. A., Smith, A. W., Davis, S. M., Smith, D. G., & Walker, B. M. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.02.012 · Cited by 133 · see citing works

Pharmacological and behavioral characteristics of 22 kHz alarm calls in rats

Brudzyński, S. M. (2001) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(01)00058-6 · Cited by 128 · see citing works

Repeated ethanol administration induces short- and long-term changes in enkephalin and dynorphin tissue concentrations in rat brain

Lindholm, S., Ploj, K., Franck, J., & Nylander, I. (2000) · Alcohol · doi:10.1016/s0741-8329(00)00118-x · Cited by 122 · see citing works

Early recovery from alcohol dependence: factors that promote or impede abstinence.

Charney, D., Zikos, E., & Gill, K. (2010) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2009.06.002 · Cited by 122 · see citing works

Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine

Wee, S., Orío, L., Ghirmai, S., Cashman, J. R., & Koob, G. F. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1563-y · Cited by 119 · see citing works

Kappa Opioid Receptor Activation in the Nucleus Accumbens Inhibits Glutamate and GABA Release Through Different Mechanisms

Hjelmstad, G. O., & Fields, H. L. (2003) · Journal of Neurophysiology · doi:10.1152/jn.01115.2002 · Cited by 119 · see citing works

The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat

Turchan-Cholewo, J. T., Przewłocka, B., Tóth, G., Lasoń, W., Borsodi, A. D., & Przewłocki, R. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00637-x · Cited by 109 · see citing works

Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence

Walker, B. M., Valdez, G. R., McLaughlin, J. P., & Bakalkin, G. Y. (2012) · Alcohol · doi:10.1016/j.alcohol.2011.10.006 · Cited by 106 · see citing works

Stress-Induced Activation of the Dynorphin/κ-Opioid Receptor System in the Amygdala Potentiates Nicotine Conditioned Place Preference

Smith, J. S., Schindler, A. G., Martinelli, E., Gustin, R. M., Bruchas, M. R., & Chavkin, C. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2980-11.2012 · Cited by 102 · see citing works

The kappa opioid receptor antagonist JDTic attenuates alcohol seeking and withdrawal anxiety

Schank, J. R., Goldstein, A., Rowe, K. E., King, C. E., Marusich, J. A., Wiley, J. L., Carroll, F. I., Thorsell, A., & Heilig, M. A. (2012) · Addiction Biology · doi:10.1111/j.1369-1600.2012.00455.x · Cited by 101 · see citing works

Kappa Opioid Receptor Inhibition of Glutamatergic Transmission in the Nucleus Accumbens Shell

Hjelmstad, G. O., & Fields, H. L. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.3.1153 · Cited by 90 · see citing works

Effects of acute ethanol on opioid peptide release in the central amygdala: an in vivo microdialysis study

Lam, M. P., Marinelli, P. W., Bai, L., & Gianoulakis, C. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1267-8 · Cited by 86 · see citing works

The endogenous opioid system in human alcoholics: molecular adaptations in brain areas involved in cognitive control of addiction

Bazov, I., Kononenko, O., Watanabe, H., Kuntić, V. S., Sarkisyan, D., Taqi, M. M., Hussain, M. Z., Nyberg, F., Yakovleva, T., & Bakalkin, G. Y. (2011) · Addiction Biology · doi:10.1111/j.1369-1600.2011.00366.x · Cited by 81 · see citing works

Ethanol withdrawal enhances the prodynorphin system activity in the rat nucleus accumbens

Przewłocka, B., Turchan, J., Lasoń, W., & Przewłocki, R. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00829-x · Cited by 80 · see citing works

A regulatory variation in OPRK1, the gene encoding the -opioid receptor, is associated with alcohol dependence

Edenberg, H. J., Wang, J., Tian, H., Pochareddy, S., Xuei, X., Wetherill, L. F., Goate, A., Hinrichs, T., Samuel Kuperman, C., Nürnberger, J. I., et al. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn068 · Cited by 74 · see citing works

Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain

D’Addario, C., Caputi, F. F., Rimondini, R., Gandolfi, O., Borrello, E. D., Candeletti, S., & Romualdi, P. (2011) · Addiction Biology · doi:10.1111/j.1369-1600.2011.00326.x · Cited by 73 · see citing works

Constitutive activity of the δ ‐opioid receptor expressed in C6 glioma cells: identification of non‐peptide δ ‐inverse agonists

Neilan, C. L., Akil, H., Woods, J. H., & Traynor, J. R. (1999) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702816 · Cited by 69 · see citing works

Alcohol-induced plasticity in the dynorphin/kappa-opioid receptor system

SIROHI, S. K., Bakalkin, G. Y., & Walker, B. M. (2012) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2012.00095 · Cited by 64 · see citing works

Enkephalins, dynorphins, and β‐endorphin in the rat dorsal horn: An immunofluorescence colocalization study

Marvizón, J. C. G., Chen, W., & Murphy, N. P. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.22130 · Cited by 54 · see citing works

The effect of intermittent alcohol vapor or pulsatile heroin on somatic and negative affective indices during spontaneous withdrawal in Wistar rats

Williams, A. M., Reis, D. J., Powell, A. S., Neira, L. J., Nealey, K. A., Ziegler, C. E., Kloss, N. D., Bilimoria, J. L., Smith, C. E., & Walker, B. M. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2691-3 · Cited by 53 · see citing works

Salvinorin A exerts opposite presynaptic controls on neurotransmitter exocytosis from mouse brain nerve terminals

Grilli, M., Neri, E., Zappettini, S., Massa, F., Bisio, A., Romussi, G., Marchi, M., & Pittaluga, A. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.07.023 · Cited by 53 · see citing works

The Relative Potency of Inverse Opioid Agonists and a Neutral Opioid Antagonist in Precipitated Withdrawal and Antagonism of Analgesia and Toxicity

SIROHI, S. K., Dighe, S. V., Madia, P. A., & Yoburn, B. C. (2009) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.109.152678 · Cited by 48 · see citing works

Toward affective circuit-based preclinical models of depression: Sensitizing dorsal PAG arousal leads to sustained suppression of positive affect in rats

Wright, J. S., & Panksepp, J. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.08.004 · Cited by 45 · see citing works

The long-lasting effects of JDTic, a kappa opioid receptor antagonist, on the expression of ethanol-seeking behavior and the relapse drinking of female alcohol-preferring (P) rats

Deehan, G. A., McKinzie, D. L., Carroll, F. I., McBride, W. J., & Rodd, Z. A. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2012.03.006 · Cited by 42 · see citing works

Chronic Ethanol Consumption Reduces δ‐and μ‐Opioid Receptor–Stimulated G‐Protein Coupling in Rat Brain

Saland, L. C., Abeyta, A., Frausto, S. F., Raymond‐Stintz, M. A., Hastings, C. M., Carta, M., Valenzuela, C. F., & Savage, D. D. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000108658.00243.bf · Cited by 36 · see citing works

Intracerebroventricular ethanol-induced conditioned place preferences are prevented by fluphenazine infusions into the nucleus accumbens of rats.

Walker, B. M., & Ettenberg, A. (2007) · Behavioral Neuroscience · doi:10.1037/0735-7044.121.2.401 · Cited by 36 · see citing works

Psychiatric disorders associated with alcoholism: 2 year follow-up of treatment.

Sánchez-Peña, J. F., Alvarez-Cotoli, P. G., & Rodríguez-Solano, J. J. (2013) · PubMed · Cited by 35 · see citing works

Conceptualizing withdrawal-induced escalation of alcohol self-administration as a learned, plasticity-dependent process

Walker, B. M. (2012) · Alcohol · doi:10.1016/j.alcohol.2012.01.001 · Cited by 23 · see citing works

Opioids and rate of positively reinforced behavior: III. Antagonism by the long-lasting kappa antagonist norbinaltorphimine.

Mj, P., Mathewson, C., & Rm, A. (1996) · PubMed · Cited by 21 · see citing works

Acute Amphetamine Exposure Selectively Desensitizes κ-Opioid Receptors in the Nucleus Accumbens

Xia, Y., Li, H., Whistler, J. L., & Hjelmstad, G. O. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301463 · Cited by 21 · see citing works

Basolateral to Central Amygdala Neural Circuits for Appetitive Behaviors

Kim, J., Zhang, X., Muralidhar, S., LeBlanc, S., & Tonegawa, S. (2017) · Neuron · doi:10.1016/j.neuron.2017.02.034 · Cited by 460 · see citing works

Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development

Koob, G. F. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000083 · Cited by 337 · see citing works

The Kappa Opioid Receptor: From Addiction to Depression, and Back

Lalanne, L., Ayrancı, G., Kieffer, B. L., & Lutz, P.-É. (2014) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2014.00170 · Cited by 227 · see citing works

Nalmefene: A Review of Its Use in the Treatment of Alcohol Dependence

Keating, G. M. (2013) · CNS Drugs · doi:10.1007/s40263-013-0101-y · Cited by 213 · see citing works

The Role of NFkB in Drug Addiction: Beyond Inflammation

Nennig, S. E., & Schank, J. R. (2016) · Alcohol and Alcoholism · doi:10.1093/alcalc/agw098 · Cited by 211 · see citing works

Pain-induced negative affect is mediated via recruitment of the nucleus accumbens kappa opioid system

Massaly, N., Copits, B. A., Wilson-Poe, A. R., Hipólito, L., Markovic, T., Yoon, H. J., Liu, S., Walicki, M. C., Bhatti, D. L., Sirohi, S., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.02.029 · Cited by 200 · see citing works

Influence of stress associated with chronic alcohol exposure on drinking

Becker, H. C. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.04.028 · Cited by 191 · see citing works

Alcohol Dependence, Withdrawal, and Relapse

Becker, H. C. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405941-2.00019-5 · Cited by 184 · see citing works

Operant alcohol self-administration in dependent rats: Focus on the vapor model

Vendruscolo, L. F., & Roberts, A. J. (2014) · Alcohol · doi:10.1016/j.alcohol.2013.08.006 · Cited by 166 · see citing works

Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala

Pleil, K. E., Lowery‐Gionta, E. G., Crowley, N. A., Li, C., Marcinkiewcz, C. A., Rose, J. H., McCall, N. M., Maldonado‐Devincci, A. M., Morrow, A. L., Jones, S. R., et al. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.06.017 · Cited by 158 · see citing works

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse

Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148 · see citing works

Supersensitive kappa opioid receptors promotes ethanol withdrawal-related behaviors and reduce dopamine signaling in the nucleus accumbens

Rose, J. H., Karkhanis, A. N., Chen, R., Gioia, D., Lopez, M. F., Becker, H. C., McCool, B. A., & Jones, S. R. (2016) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv127 · Cited by 136 · see citing works

Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment

Crowley, N. A., & Kash, T. L. (2015) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2015.01.001 · Cited by 132 · see citing works

Early-Life Social Isolation Stress Increases Kappa Opioid Receptor Responsiveness and Downregulates the Dopamine System

Karkhanis, A. N., Rose, J. H., Weiner, J. L., & Jones, S. R. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.21 · Cited by 131 · see citing works

A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists

Mores, K. L., Cummins, B. R., Cassell, R. J., & van Rijn, R. M. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00407 · Cited by 112 · see citing works

Nalmefene for the management of alcohol dependence: review on its pharmacology, mechanism of action and meta-analysis on its clinical efficacy

Mann, K. F., Torup, L., Sørensen, P. S., Gual, A., Swift, R. M., Walker, B. M., & van den Brink, W. (2016) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2016.10.008 · Cited by 97 · see citing works

Endogenous opiates and behavior: 2014

Bodnar, R. J. (2015) · Peptides · doi:10.1016/j.peptides.2015.10.009 · Cited by 85 · see citing works

Neurochemical mechanisms of alcohol withdrawal

Becker, H. C., & Mulholland, P. J. (2014) · Handbook of clinical neurology · doi:10.1016/b978-0-444-62619-6.00009-4 · Cited by 83 · see citing works

Postdependent state in rats as a model for medication development in alcoholism

Meinhardt, M. W., & Sommer, W. H. (2014) · Addiction Biology · doi:10.1111/adb.12187 · Cited by 83 · see citing works

Role of the Dynorphin/Kappa Opioid Receptor System in the Motivational Effects of Ethanol

Anderson, R. I., & Becker, H. C. (2017) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.13406 · Cited by 79 · see citing works

Kappa opioid receptor and dynorphin signaling in the central amygdala regulates alcohol intake

Bloodgood, D. W., Hardaway, J. A., Stanhope, C. M., Pati, D., Pina, M. M., Neira, S., Desai, S., Boyt, K. M., Palmiter, R. D., & Kash, T. L. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0690-z · Cited by 71 · see citing works

Preclinical evaluation of the kappa-opioid receptor antagonist CERC-501 as a candidate therapeutic for alcohol use disorders

Domi, E., Barbier, E., Augier, E., Augier, G., Gehlert, D. R., Barchiesi, R., Thorsell, A., Holm, L., & Heilig, M. A. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0015-y · Cited by 73 · see citing works

Stress-Induced Enhancement of Ethanol Intake in C57BL/6J Mice with a History of Chronic Ethanol Exposure: Involvement of Kappa Opioid Receptors

Anderson, R. I., Lopez, M. F., & Becker, H. C. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00045 · Cited by 69 · see citing works

Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: role of kappa opioid receptors

Karkhanis, A. N., Huggins, K. N., Rose, J. H., & Jones, S. R. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.07.022 · Cited by 68 · see citing works

Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice

Anderson, R. I., Lopez, M. F., Griffin, W. C., Haun, H. L., Bloodgood, D. W., Pati, D., Boyt, K. M., Kash, T. L., & Becker, H. C. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-018-0294-3 · Cited by 68 · see citing works

Kappa Opioid Receptor-Mediated Dysregulation of Gamma-Aminobutyric Acidergic Transmission in the Central Amygdala in Cocaine Addiction

Kallupi, M., Wee, S., Edwards, S., Whitfield, T. W., Oleata, C. S., Luu, G., Schmeichel, B. E., Koob, G. F., & Roberto, M. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.04.028 · Cited by 67 · see citing works

Voluntary Ethanol Intake Predicts κ-Opioid Receptor Supersensitivity and Regionally Distinct Dopaminergic Adaptations in Macaques

Siciliano, C. A., Calipari, E. S., Carlson, V. C. C., Helms, C. M., Lovinger, D. M., Grant, K. A., & Jones, S. R. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.4820-14.2015 · Cited by 61 · see citing works

Driving the downward spiral: alcohol-induced dysregulation of extended amygdala circuits and negative affect

Centanni, S. W., Bedse, G., Patel, S., & Winder, D. G. (2019) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.14178 · Cited by 58 · see citing works

Forced swim stress increases ethanol consumption in C57BL/6J mice with a history of chronic intermittent ethanol exposure

Anderson, R. I., Lopez, M. F., & Becker, H. C. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4257-2 · Cited by 56 · see citing works

Intermittent Access to Ethanol Drinking Facilitates the Transition to Excessive Drinking After Chronic Intermittent Ethanol Vapor Exposure

Kimbrough, A., Kim, S., Cole, M., Brennan, M., & George, O. (2017) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13434 · Cited by 54 · see citing works

CRF 1 Receptor‐Dependent Increases in Irritability‐Like Behavior During Abstinence from Chronic Intermittent Ethanol Vapor Exposure

Kimbrough, A., de Guglielmo, G., Kononoff, J., Kallupi, M., Zorrilla, E. P., & George, O. (2017) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13484 · Cited by 51 · see citing works

Maladaptive behavioral regulation in alcohol dependence: Role of kappa-opioid receptors in the bed nucleus of the stria terminalis

Erikson, C. M., Wei, G., & Walker, B. M. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.07.034 · Cited by 50 · see citing works

Dynorphin and its role in alcohol use disorder

Karkhanis, A. N., & Al-Hasani, R. (2020) · Brain Research · doi:10.1016/j.brainres.2020.146742 · Cited by 47 · see citing works

Asymmetry of the Endogenous Opioid System in the Human Anterior Cingulate: a Putative Molecular Basis for Lateralization of Emotions and Pain

Watanabe, H., Fitting, S., Hussain, M. Z., Kononenko, O., Iatsyshyna, A. P., Yoshitake, T., Kehr, J., Alkass, K., Druid, H., Wadensten, H., et al. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht204 · Cited by 45 · see citing works

Nalmefene: a new approach to the treatment of alcohol dependence

Paillé, F., & Martini, H. (2014) · Substance Abuse and Rehabilitation · doi:10.2147/sar.s45666 · Cited by 44 · see citing works

Comparison of three automated systems for urine chemistry and sediment analysis in routine laboratory practice.

Budak, Y., & Huysal, K. (2011) · PubMed · Cited by 44 · see citing works

Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit/Stress Surfeit Disorder

Koob, G. F., & Vendruscolo, L. F. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_424 · Cited by 44 · see citing works

Dissociating Motivational From Physiological Withdrawal in Alcohol Dependence: Role of Central Amygdala κ-Opioid Receptors

Kissler, J. L., & Walker, B. M. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.183 · Cited by 43 · see citing works

Role of κ-Opioid Receptors in the Bed Nucleus of Stria Terminalis in Reinstatement of Alcohol Seeking

Lê, A. D., Funk, D. R., Coen, K. M., Tamadon, S., & Shaham, Y. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.120 · Cited by 41 · see citing works

A balancing act: the role of pro‐ and anti‐stress peptides within the central amygdala in anxiety and alcohol use disorders

Walker, L. C. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15301 · Cited by 37 · see citing works

Dynorphin/kappa opioid receptor system regulation on amygdaloid circuitry: Implications for neuropsychiatric disorders

Limoges, A., Yarur, H. E., & Tejeda, H. A. (2022) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2022.963691 · Cited by 33 · see citing works

An Animal Model of Alcohol Dependence to Screen Medications for Treating Alcoholism

Becker, H. C., & Lopez, M. F. (2016) · International review of neurobiology · doi:10.1016/bs.irn.2016.02.006 · Cited by 32 · see citing works

Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics

Bazov, I., Sarkisyan, D., Kononenko, O., Watanabe, H., Yakovleva, T., Hansson, A. C., Sommer, W. H., Spanagel, R., & Bakalkin, G. Y. (2018) · Molecular Neurobiology · doi:10.1007/s12035-017-0844-4 · Cited by 34 · see citing works

Dynorphin/Kappa Opioid Receptor Activity Within the Extended Amygdala Contributes to Stress-Enhanced Alcohol Drinking in Mice

Haun, H. L., Lebonville, C. L., Solomon, M. G., Griffin, W. C., Lopez, M. F., & Becker, H. C. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.01.002 · Cited by 33 · see citing works

Alcohol: A stimulant activating brain stress responsive systems with persistent neuroadaptation

Zhou, Y., & Kreek, M. J. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.05.044 · Cited by 33 · see citing works

Behavioral, neurobiological, and neurochemical mechanisms of ethanol self-administration: A translational review

Vena, A. A., Zandy, S. L., Cofresí, R. U., & Gonzales, R. A. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107573 · Cited by 32 · see citing works

Anticipatory 50kHz ultrasonic vocalizations are associated with escalated alcohol intake in dependent rats

Buck, C. L., Malavar, J. C., George, O., Koob, G. F., & Vendruscolo, L. F. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.06.003 · Cited by 32 · see citing works

Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure

Rose, J. L., Karkhanis, A. N., Steiniger‐Brach, B., & Jones, S. R. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17081216 · Cited by 32 · see citing works

Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure

Siciliano, C. A., Karkhanis, A. N., Holleran, K. M., Melchior, J. R., & Jones, S. R. (2018) · Handbook of experimental pharmacology · doi:10.1007/164_2018_106 · Cited by 32 · see citing works

Biobehavioral Interactions Between Stress and Alcohol

Weera, M. M. (2019) · Alcohol research · doi:10.35946/arcr.v40.1.04 · Cited by 32 · see citing works

Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment

Kuzmin, A., Chefer, V. I., Bazov, I., Meis, J., Ögren, S. O., Shippenberg, T. S., & Bakalkin, G. Y. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.72 · Cited by 30 · see citing works

Kappa opioid receptors in the bed nucleus of the stria terminalis regulate binge-like alcohol consumption in male and female mice

Haun, H. L., Griffin, W. C., Lopez, M. F., & Becker, H. C. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.107984 · Cited by 30 · see citing works

The opioid receptors as targets for drug abuse medication

Noble, F., Lenoir, M., & Marie, N. (2015) · British Journal of Pharmacology · doi:10.1111/bph.13190 · Cited by 29 · see citing works

Age-dependent regulation of GABA transmission by kappa opioid receptors in the basolateral amygdala of Sprague-Dawley rats

Przybysz, K. R., Werner, D. F., & Diaz, M. R. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.01.036 · Cited by 29 · see citing works

Preclinical Studies on Nalfurafine (TRK-820), a Clinically Used KOR Agonist

Zhou, Y., Freeman, K. B., Setola, V., Cao, D., Kaski, S. W., Kreek, M. J., & Liu‐Chen, L. (2021) · Handbook of experimental pharmacology · doi:10.1007/164_2021_443 · Cited by 27 · see citing works

Alcohol‐Induced Changes in Opioid Peptide Levels in Adolescent Rats Are Dependent on Housing Conditions

Palm, S., & Nylander, I. (2014) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12586 · Cited by 26 · see citing works

Dissociable Effects of Kappa-Opioid Receptor Activation on Impulsive Phenotypes in Wistar Rats

Walker, B. M., & Kissler, J. L. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.129 · Cited by 25 · see citing works

Environmental stressors and alcoholism development: Focus on molecular targets and their epigenetic regulation

Pucci, M., Bonaventura, M. V. M. D., Wille‐Bille, A., Fernández, M. S., Maccarrone, M., Pautassi, R. M., Cifani, C., & D’Addario, C. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.07.004 · Cited by 24 · see citing works

The kappa opioid receptor modulates GABA neuron excitability and synaptic transmission in midbrain projections from the insular cortex

Pina, M. M., Pati, D., Hwa, L. S., Wu, S. Y., Mahoney, A. A., Omenyi, C. G., Navarro, M., & Kash, T. L. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.107831 · Cited by 24 · see citing works

Adolescent forced swim stress increases social anxiety-like behaviors and alters kappa opioid receptor function in the basolateral amygdala of male rats

Varlinskaya, E. I., Johnson, J. M., Przybysz, K. R., Terrence Deak, B., & Diaz, M. R. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109812 · Cited by 24 · see citing works

Combination of Clinically Utilized Kappa‐Opioid Receptor Agonist Nalfurafine With Low‐Dose Naltrexone Reduces Excessive Alcohol Drinking in Male and Female Mice

Zhou, Y., & Kreek, M. J. (2019) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14033 · Cited by 23 · see citing works

Maturational alterations in constitutive activity of medial prefrontal cortex kappa‐opioid receptors in Wistar rats

SIROHI, S. K., & Walker, B. M. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13279 · Cited by 23 · see citing works

The role of matrix metalloproteinase‐9 in negative reinforcement learning and plasticity in alcohol dependence

Go, B. S., SIROHI, S. K., & Walker, B. M. (2019) · Addiction Biology · doi:10.1111/adb.12715 · Cited by 23 · see citing works

Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone

Zhou, Y., Crowley, R. S., Ben, K. T., Prisinzano, T. E., & Kreek, M. J. (2017) · Brain Research · doi:10.1016/j.brainres.2017.02.027 · Cited by 21 · see citing works

Effect of chronic alcohol vapor exposure on reinstatement of alcohol seeking induced by U50,488

Funk, D. R., Coen, K. M., Tamadon, S., & Lê, A. D. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.01.017 · Cited by 21 · see citing works

Binge-like intake of HFD attenuates alcohol intake in rats

SIROHI, S. K., Cleef, A. V., & Davis, J. F. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.10.006 · Cited by 21 · see citing works

Involvement of Activated Brain Stress Responsive Systems in Excessive and “Relapse” Alcohol Drinking in Rodent Models: Implications for Therapeutics

Zhou, Y., & Kreek, M. J. (2018) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.117.245621 · Cited by 19 · see citing works

Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics

Bazov, I., Sarkisyan, D., Kononenko, O., Watanabe, H., Karpyak, V. M., Yakovleva, T., & Bakalkin, G. Y. (2018) · Translational Psychiatry · doi:10.1038/s41398-017-0075-5 · Cited by 19 · see citing works

Effects of Rearing Conditions on Behaviour and Endogenous Opioids in Rats with Alcohol Access during Adolescence

Palm, S., Daoura, L., Roman, E., & Nylander, I. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076591 · Cited by 18 · see citing works

Contribution of Dynorphin and Orexin Neuropeptide Systems to the Motivational Effects of Alcohol

Anderson, R. I., Moorman, D. E., & Becker, H. C. (2018) · Handbook of experimental pharmacology · doi:10.1007/164_2018_100 · Cited by 18 · see citing works

Evaluation of dynorphin and kappa-opioid receptor level in the human blood lymphocytes and plasma: Possible role as a biomarker in severe opioid use disorder

Shahkarami, K., Vousooghi, N., Golab, F., Mohsenzadeh, A., Baharvand, P., Sadat‐Shirazi, M., Babhadi‐Ashar, N., Shakeri, A., & Zarrindast, M. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.107638 · Cited by 18 · see citing works

Buprenorphine Pharmacodynamics: A Bridge to Understanding Buprenorphine Clinical Benefits

Davis, M. P. (2025) · Drugs · doi:10.1007/s40265-024-02128-y · Cited by 18 · see citing works

Differential regulation of alcohol consumption and reward by the transcriptional cofactor LMO4

Maiya, R., Pomrenze, M. B., Tran, T. N. A., Tiwari, G. R., Beckham, A., Paul, M. T., Mayfield, R. D., & Messing, R. O. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0706-8 · Cited by 17 · see citing works

Alcohol Dependence in Rats Is Associated with Global Changes in Gene Expression in the Central Amygdala

Kisby, B. R., Farris, S. P., McManus, M. M., Varodayan, F. P., Roberto, M., Harris, R. A., & Ponomarev, I. (2021) · Brain Sciences · doi:10.3390/brainsci11091149 · Cited by 15 · see citing works

Dysregulated kappa‐opioid receptors in the medial prefrontal cortex contribute to working memory deficits in alcohol dependence

Wei, G., Sirohi, S., & Walker, B. M. (2022) · Addiction Biology · doi:10.1111/adb.13138 · Cited by 15 · see citing works

Behavioral and Neurobiological Consequences of Hedonic Feeding on Alcohol Drinking

Brutman, J. N., Davis, J. F., & Sirohi, S. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200206092231 · Cited by 12 · see citing works

Los Antagonistas de los Receptores Opioides en el Tratamiento del Alcoholismo

Serecigni, J. G. (2015) · Adicciones · doi:10.20882/adicciones.708 · Cited by 14 · see citing works

Kappa‐opioid receptors differentially regulate low and high levels of ethanol intake in female mice

Veer, A. V., Smith, K. L., Cohen, B. M., Carlezon, W. A., & Bechtholt, A. J. (2016) · Brain and Behavior · doi:10.1002/brb3.523 · Cited by 14 · see citing works

Effects of mesyl salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice

Zhou, Y., Crowley, R. S., Prisinzano, T. E., & Kreek, M. J. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.02.056 · Cited by 14 · see citing works

Clinically utilized kappa-opioid receptor agonist nalfurafine combined with low-dose naltrexone prevents alcohol relapse-like drinking in male and female mice

Zhou, Y., & Kreek, M. J. (2019) · Brain Research · doi:10.1016/j.brainres.2019.146410 · Cited by 14 · see citing works

Nalmefene Hydrochloride: Potential Implications for Treating Alcohol and Opioid Use Disorder

Green, M., Veltri, C. A., & Grundmann, O. (2024) · Substance Abuse and Rehabilitation · doi:10.2147/sar.s431270 · Cited by 13 · see citing works

Nuclear transcriptional changes in hypothalamus of Pomc enhancer knockout mice after excessive alcohol drinking

Zhou, Y., Liang, Y., Low, M. J., & Kreek, M. J. (2019) · Genes Brain & Behavior · doi:10.1111/gbb.12600 · Cited by 13 · see citing works

A critical review of effects on ethanol intake of the dynorphin/kappa opioid receptor system in the extended amygdala: From inhibition to stimulation

Pirino, B. E., Kelley, A. M., Karkhanis, A. N., & Barson, J. R. (2023) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.15078 · Cited by 13 · see citing works

Effect of PDYN and OPRK1 polymorphisms on the risk of alcohol use disorder and the intensity of depressive symptoms

Özkan-Kotiloğlu, S., Kaya-Akyüzlü, D., Yurdakul, R., Yıldırım, M. A., & İlhan, İ. Ö. (2023) · Alcohol and Alcoholism · doi:10.1093/alcalc/agad036 · Cited by 12 · see citing works

Air-puff induced vocalizations: A novel approach to detecting negative affective state following concussion in rats

Browning, J. R., Whiteman, A. C., Leung, L. Y., Lu, X. M., & Shear, D. A. (2016) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2016.10.017 · Cited by 12 · see citing works

Nicotine increases alcohol self‐administration in male rats via a μ‐opioid mechanism within the mesolimbic pathway

Domi, E., Xu, L. X., Pätz, M., Nordeman, A., Augier, G., Holm, L., Toivainen, S., Augier, E., Hansson, A. C., & Heilig, M. A. (2020) · British Journal of Pharmacology · doi:10.1111/bph.15210 · Cited by 12 · see citing works

Brain proteomic atlas of alcohol use disorder in adult males

Teng, P.-N., Barakat, W., Tran, S. M., Tran, Z. M., Bateman, N. W., Conrads, K. A., Wilson, K. N., Oliver, J., Gist, G. D., Hood, B. L., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02605-0 · Cited by 11 · see citing works

Moderate adolescent chronic intermittent ethanol exposure sex-dependently disrupts synaptic transmission and kappa opioid receptor function in the basolateral amygdala of adult rats

Przybysz, K. R., Gamble, M. E., & Diaz, M. R. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108512 · Cited by 11 · see citing works

The Dynorphin/-Opioid Receptor System at the Interface of Hyperalgesia/Hyperkatifeia and Addiction

Marchette, R. C. N., Vendruscolo, L. F., & Koob, G. F. (2025) · Current Addiction Reports · doi:10.1007/s40429-025-00618-x · Cited by 13 · see citing works

Recapitulating phenotypes of alcohol dependence via overexpression of Oprk1 in the ventral tegmental area of non-dependent TH::Cre rats

Lepreux, G., Shinn, G. E., Wei, G., Suko, A. V., Concepcion, G., Sirohi, S., Go, B. S., Bruchas, M. R., & Walker, B. M. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109457 · Cited by 10 · see citing works

Ethanol and Naltrexone Have Distinct Effects on the Lateral Nano-organization of Mu and Kappa Opioid Receptors in the Plasma Membrane

Tobin, S. J., Wakefield, D. L., Terenius, L. Y., Vukojević, V. B., & Jovanović‐Talisman, T. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00488 · Cited by 10 · see citing works

Investigational therapies for the pharmacological treatment of alcoholism

Hillemacher, T., Leggio, L., & Heberlein, A. (2014) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2014.954037 · Cited by 10 · see citing works

Sex- and β-arrestin-dependent effects of kappa opioid receptor-mediated ethanol consumption

French, A. R., Gutridge, A. M., Yuan, J., Royer, Q. H., & van Rijn, R. M. (2022) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2022.173377 · Cited by 9 · see citing works

Leveraging Neural Networks in Preclinical Alcohol Research

Smith, L. C., & Kimbrough, A. (2020) · Brain Sciences · doi:10.3390/brainsci10090578 · Cited by 8 · see citing works

Clinical moderators of response to nalmefene in a randomized-controlled trial for alcohol dependence: An exploratory analysis

Hashimoto, N., Habu, H., Takao, S., Sakamoto, S., Okahisa, Y., Matsuo, K., Takaki, M., Kishi, Y., & Yamada, N. (2022) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2022.109365 · Cited by 8 · see citing works

Acute and chronic alcohol modulation of extended amygdala calcium dynamics

Roland, A. V., Chao, T.-H. H., Hon, O. J., Machinski, S. N., Sides, T. R., Lee, S. I., Shih, Y. I., & Kash, T. L. (2024) · Alcohol · doi:10.1016/j.alcohol.2024.02.004 · Cited by 9 · see citing works

Association of opioid receptor gene polymorphisms with drinking severity and impulsivity related to alcohol use disorder in a Korean population

Park, C. I., Hwang, S. S., Kim, H. W., Kang, J. I., Lee, S., & Kim, S. J. (2019) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13138 · Cited by 8 · see citing works

Targeting the Opioid Receptors: A Promising Therapeutic Avenue for Treatment in “Heavy Drinking Smokers”

Domi, A., Barbier, E., Adermark, L., & Domi, E. (2020) · Alcohol and Alcoholism · doi:10.1093/alcalc/agaa139 · Cited by 8 · see citing works

The amygdalar opioid system

Wilson, M. A., & McDonald, A. J. (2020) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-815134-1.00008-8 · Cited by 7 · see citing works

Kappa-Opioid Receptor Antagonism: A Mechanism for Treatment of Relief Drinking?

Heilig, M. A., & Schank, J. R. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.03.004 · Cited by 5 · see citing works

Dissociating Motivational From Physiological Withdrawal in Alcohol Dependence: Role of Central Amygdala κ-Opioid Receptors

Kissler, J. L., & Walker, B. M. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.183 · Cited by 43 · see citing works

Maladaptive behavioral regulation in alcohol dependence: Role of kappa-opioid receptors in the bed nucleus of the stria terminalis

Erikson, C. M., Wei, G., & Walker, B. M. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.07.034 · Cited by 50 · see citing works

Kappa-opioid receptor antagonism in the nucleus accumbens shell distinguishes escalated alcohol consumption and negative affective-like behavior from physiological withdrawal in alcohol-dependence

Lepreux, G., Henricks, A. M., Wei, G., Go, B. S., Erikson, C. M., Abella, R. M., Pham, A., & Walker, B. M. (2024) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2024.173840 · Cited by 6 · see citing works

The Role of the Dynorphin/Kappa Opioid Receptor System in the Actions of Alcohol

Sureshkumar, K., Go, J., Tran, M., Malhotra, S., Ahmad, S. M., & Lutfy, K. (2022) · Psychoactives · doi:10.3390/psychoactives1020006 · Cited by 5 · see citing works