Effect of the Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 2 AZD8529 on Incubation of Methamphetamine Craving After Prolonged Voluntary Abstinence in a Rat Model
Open accessAbstract
Background Cue-induced methamphetamine craving increases after prolonged forced (experimenter-imposed) abstinence from the drug (incubation of methamphetamine craving). Here, we determined whether this incubation phenomenon would occur under conditions that promote voluntary (self-imposed) abstinence. We also determined the effect of the novel metabotropic glutamate receptor 2 positive allosteric modulator, AZD8529, on incubation of methamphetamine craving after forced or voluntary abstinence.Methods We trained rats to self-administer palatable food (6 sessions) and then to self-administer methamphetamine under two conditions: 12 sessions (9 hours/day) or 50 sessions (3 hours/day). We then assessed cue-induced methamphetamine seeking in extinction tests after 1 or 21 abstinence days. Between tests, the rats underwent either forced abstinence (no access to the food- or drug-paired levers) or voluntary abstinence (achieved via a discrete choice procedure between methamphetamine and palatable food; 20 trials per day) for 19 days. We also determined the effect of subcutaneous injections of AZD8529 (20 and 40 mg/kg) on cue-induced methamphetamine seeking 1 day or 21 days after forced or voluntary abstinence.Results Under both training and abstinence conditions, cue-induced methamphetamine seeking in the extinction tests was higher after 21 abstinence days than after 1 day (incubation of methamphetamine craving). AZD8529 decreased cue-induced methamphetamine seeking on day 21 but not day 1 of forced or voluntary abstinence.Conclusions We introduce a novel animal model to study incubation of drug craving and cue-induced drug seeking after prolonged voluntary abstinence, mimicking the human condition of relapse after successful contingency management treatment. Our data suggest that positive allosteric modulators of metabotropic glutamate receptor 2 should be considered for relapse prevention.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In animal models, animals extensively trained to self-administer drugs will readily forego the drug if offered a potent non-drug alternative.
“The critical role of alternative reinforcers was elegantly brought into modern neuroscience by Ahmed et al., who showed that rats extensively trained to self-administer cocaine would readily forego the drug if offered a sweet solution as an alternative [103].This was later also found to be the case for heroin [103], methamphetamine [104] and alcohol [105].”
From Addiction as a brain disease revised: why it still matters, and the need for consilience (2021) · cites this paper as [104]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works
Goldstein, R. Z., & Volkow, N. D. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1642 · Cited by 2,667 · see citing works
Transition from Moderate to Excessive Drug Intake: Change in Hedonic Set Point
Ahmed, S. H., & Koob, G. F. (1998) · Science · doi:10.1126/science.282.5387.298 · Cited by 1,159 · see citing works
Abstinence Symptomatology and Psychiatric Diagnosis in Cocaine Abusers
Gawin, F. H. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800020013003 · Cited by 1,143 · see citing works
Evidence for Addiction-like Behavior in the Rat
Deroche-Gamonet, V., Belin, D., & Piazza, P. V. (2004) · Science · doi:10.1126/science.1099020 · Cited by 1,135 · see citing works
Incubation of cocaine craving after withdrawal
Grimm, J. W., Hope, B. T., Wise, R. A., & Shaham, Y. (2001) · Nature · doi:10.1038/35084134 · Cited by 1,003 · see citing works
Self-citationSchoepp, D. D. (2001) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)29296-x · Cited by 693 · see citing works
Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission
Kalivas, P. W., Volkow, N., & Seamans, J. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.005 · Cited by 657 · see citing works
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure
Epstein, D., Preston, K., Stewart, J., & Shaham, Y. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0529-6 · Cited by 634 · see citing works
Self-citationNeurobiology of the incubation of drug craving
Pickens, C. L., Airavaara, M., Theberge, F. R. M., Fanous, S., Hope, B. T., & Shaham, Y. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2011.06.001 · Cited by 634 · see citing works
Self-citationIntense Sweetness Surpasses Cocaine Reward
Lenoir, M., Serre, F., Cantin, L., & Ahmed, S. H. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000698 · Cited by 608 · see citing works
Classical Conditioning in Drug‐Dependent Humansa
OʼBRIEN, C. P., Childress, A. R., McLellan, A. T., & Ehrman, R. N. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb25984.x · Cited by 489 · see citing works
Opiate versus psychostimulant addiction: the differences do matter
Badiani, A., Belin, D., Epstein, D. H., Calu, D. J., & Shaham, Y. (2011) · Nature reviews. Neuroscience · doi:10.1038/nrn3104 · Cited by 466 · see citing works
Self-citationBossert, J. M., Marchant, N. J., Calu, D. J., & Shaham, Y. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3120-y · Cited by 453 · see citing works
Self-citationIncubation of cocaine craving after withdrawal: a review of preclinical data
Lü, L., Grimm, J. W., Hope, B. T., & Shaham, Y. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.06.027 · Cited by 443 · see citing works
Self-citationNeisewander, J. L., Baker, D. L., Fuchs, R. A., Tran-Nguyen, L. T. L., Palmer, A., & Marshall, J. F. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-02-00798.2000 · Cited by 432 · see citing works
Clinical Implications of Reinforcement as a Determinant of Substance Use Disorders
Higgins, S. T., Heil, S. H., & Lussier, J. P. (2004) · Annual Review of Psychology · doi:10.1146/annurev.psych.55.090902.142033 · Cited by 393 · see citing works
A multi‐site comparison of psychosocial approaches for the treatment of methamphetamine dependence
Rawson, R. A., Marinelli‐Casey, P., Anglin, M. D., Dickow, A., Frazier, Y., Gallagher, C., Galloway, G. P., Herrell, J., Huber, A., McCann, M. J., et al. (2004) · Addiction · doi:10.1111/j.1360-0443.2004.00707.x · Cited by 387 · see citing works
Improvements in the community-reinforcement approach to alcoholism
Azrin, N. H. (1976) · Behaviour Research and Therapy · doi:10.1016/0005-7967(76)90021-8 · Cited by 371 · see citing works
Tamaru, Y., Nomura, S., Mizuno, N., & Shigemoto, R. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00305-0 · Cited by 345 · see citing works
Ma, Y.-Y., Lee, B. R., Wang, X., Guo, C., Liu, L., Cui, R., Lan, Y., Balcita-Pedicino, J. J., Wolf, M. E., Sesack, S. R., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.023 · Cited by 344 · see citing works
Self-citationConn, P. J., Lindsley, C. W., & Jones, C. K. (2008) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2008.10.006 · Cited by 330 · see citing works
Why behavior change is difficult to sustain
Bouton, M. E. (2014) · Preventive Medicine · doi:10.1016/j.ypmed.2014.06.010 · Cited by 322 · see citing works
Lee, B. R., Ma, Y., Huang, Y. H., Wang, X., Otaka, M., Ishikawa, M., Neumann, P. A., Graziane, N., Brown, T. E., Beroun, A., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3533 · Cited by 297 · see citing works
Self-citationThe anxiogenic drug yohimbine reinstates methamphetamine seeking in a rat model of drug relapse
Shepard, J. D., Bossert, J. M., Liu, S. Y., & Shaham, Y. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.02.032 · Cited by 295 · see citing works
Self-citationMonn, J. A., Valli, M. J., Massey, S. M., Hansen, M. M., Kress, T. J., Wepsiec, J. P., Harkness, A. R., John L. Grutsch, Wright, R. A., Johnson, B. G., et al. (1999) · Journal of Medicinal Chemistry · doi:10.1021/jm980616n · Cited by 293 · see citing works
Shalev, U., Morales, M., Hope, B. T., Yap, J. J., & Shaham, Y. (2001) · Psychopharmacology · doi:10.1007/s002130100748 · Cited by 290 · see citing works
Self-citationThe validity of the reinstatement model of craving and relapse to drug use
Katz, J. L., & Higgins, S. T. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1441-y · Cited by 273 · see citing works
Effects of Length of Abstinence on Decision-Making and Craving in Methamphetamine Abusers
Wang, G., Shi, J., Chen, N., Xu, L., Li, J., Li, P., Sun, Y., & Lu, L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068791 · Cited by 261 · see citing works
A Role of Ventral Tegmental Area Glutamate in Contextual Cue-Induced Relapse to Heroin Seeking
Bossert, J. M., Liu, S. Y., Lu, L., & Shaham, Y. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3207-04.2004 · Cited by 241 · see citing works
Self-citationAhmed, S. H. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.04.005 · Cited by 240 · see citing works
Baptista, M. A. S., Martin‐Fardon, R., & Weiss, F. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0176-04.2004 · Cited by 235 · see citing works
Incubation of Cue-Induced Cigarette Craving During Abstinence in Human Smokers
Bedi, G., Preston, K. L., Epstein, D. H., Heishman, S. J., Marrone, G. F., Shaham, Y., & de Wit, H. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.07.014 · Cited by 235 · see citing works
Self-citationHigh Impulsivity Predicts Relapse to Cocaine-Seeking After Punishment-Induced Abstinence
Economidou, D., Pelloux, Y., Robbins, T. W., Dalley, J. W., & Everitt, B. J. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.12.008 · Cited by 234 · see citing works
Contingency Management for Treatment of Substance Abuse
Stitzer, M. L., & Petry, N. M. (2006) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.2.022305.095219 · Cited by 232 · see citing works
A multistep general theory of transition to addiction
Piazza, P. V., & Deroche-Gamonet, V. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3224-4 · Cited by 227 · see citing works
The ups and downs of addiction: role of metabotropic glutamate receptors
Kenny, P. J., & Markou, A. (2004) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2004.03.009 · Cited by 223 · see citing works
The science of making drug-addicted animals
Ahmed, S. H. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.08.014 · Cited by 197 · see citing works
Liechti, M. E., Lhuillier, L., Kaupmann, K., & Markou, A. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.1766-07.2007 · Cited by 193 · see citing works
Lü, L., Uejima, J. L., Gray, S. M., Bossert, J. M., & Shaham, Y. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.011 · Cited by 192 · see citing works
Self-citationPeters, J., & Kalivas, P. W. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0372-9 · Cited by 190 · see citing works
Cocaine Is Low on the Value Ladder of Rats: Possible Evidence for Resilience to Addiction
Cantin, L., Lenoir, M., Augier, E., Vanhille, N., Dubreucq, S., Serre, F., Vouillac‐Mendoza, C., & Ahmed, S. H. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011592 · Cited by 190 · see citing works
Modulation of Group II Metabotropic Glutamate Receptor Signaling by Chronic Cocaine
Xi, Z., Ramamoorthy, S., Baker, D. L., Shen, H., Samuvel, D. J., & Kalivas, P. W. (2002) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.102.039735 · Cited by 181 · see citing works
Galici, R., Jones, C. K., Hemstapat, R., Nong, Y., Echemendia, N. G., Williams, L. C., de Paulis, T., & Conn, P. J. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.102046 · Cited by 169 · see citing works
Lü, L., Grimm, J. W., Dempsey, J., & Shaham, Y. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1860-4 · Cited by 168 · see citing works
Self-citationThe reinstatement model and relapse prevention: a clinical perspective
Epstein, D., & Preston, K. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1470-6 · Cited by 167 · see citing works
The Central Amygdala Nucleus is Critical for Incubation of Methamphetamine Craving
Li, X., Zeric, T., Kambhampati, S., Bossert, J. M., & Shaham, Y. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.320 · Cited by 163 · see citing works
Self-citationSchaffhauser, H., Rowe, B. A., Morales, S., Chavez-Noriega, L. E., Yin, R., Jachec, C., Rao, S. P., Bain, G., Pinkerton, A. B., Vernier, J., et al. (2003) · Molecular Pharmacology · doi:10.1124/mol.64.4.798 · Cited by 160 · see citing works
Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving
Loweth, J. A., Scheyer, A. F., Milovanovic, M., LaCrosse, A. L., Flores-Barrera, E., Werner, C. T., Li, X., Ford, K. A., Le, T., Olive, M. F., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3590 · Cited by 157 · see citing works
Self-citationIncubation of alcohol craving during abstinence in patients with alcohol dependence
Li, P., Wu, P., Xin, X., Fan, Y., Wang, G., Wang, F., Ma, M., Xue, M., Luo, Y., Yang, F., et al. (2014) · Addiction Biology · doi:10.1111/adb.12140 · Cited by 156 · see citing works
Reinforcement of Competing Behavior during Extinction
Leitenberg, H., Rawson, R. A., & Bath, K. E. (1970) · Science · doi:10.1126/science.169.3942.301 · Cited by 151 · see citing works
Opponent process properties of self-administered cocaine
Ettenberg, A. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2003.11.009 · Cited by 150 · see citing works
Recent developments in animal models of drug relapse
Marchant, N. J., Li, X., & Shaham, Y. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.01.003 · Cited by 148 · see citing works
Self-citationNeurobiology of addiction versus drug use driven by lack of choice
Ahmed, S. H., Lenoir, M., & Guillem, K. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.01.028 · Cited by 135 · see citing works
Podlesnik, C. A., Jimenez‐Gomez, C., & Shahan, T. A. (2006) · Behavioural Pharmacology · doi:10.1097/01.fbp.0000224385.09486.ba · Cited by 132 · see citing works
Pharmacotherapy of Methamphetamine Addiction: An Update
Elkashef, A. M., Vocci, F. J., Hanson, G. R., White, J. M., WICKES, W. A., & Tiihonen, J. (2008) · Substance Abuse · doi:10.1080/08897070802218554 · Cited by 121 · see citing works
Incubation of Methamphetamine and Palatable Food Craving after Punishment-Induced Abstinence
Krasnova, I. N., Marchant, N. J., Ladenheim, B., McCoy, M. T., Panlilio, L. V., Bossert, J. M., Shaham, Y., & Cadet, J. L. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.50 · Cited by 121 · see citing works
Self-citationContext-Induced Relapse to Alcohol Seeking After Punishment in a Rat Model
Marchant, N. J., Khuc, T., Pickens, C. L., Bonci, A., & Shaham, Y. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.07.007 · Cited by 120 · see citing works
Self-citationTheberge, F. R., Li, X., Kambhampati, S., Pickens, C. L., St. Laurent, R., Bossert, J. M., Baumann, M. H., Hutchinson, M. R., Rice, K. C., Watkins, L. R., et al. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.12.019 · Cited by 119 · see citing works
Self-citationBehavioral self-control program for Windows: Results of a controlled clinical trial.
Hester, R. K., & Delaney, H. D. (1997) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.65.4.686 · Cited by 117 · see citing works
Behavioral self-control program for Windows: Results of a controlled clinical trial.
Hester, R. K., & Delaney, H. D. (1997) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.65.4.686 · Cited by 117 · see citing works
Glutamate-based therapeutic approaches: allosteric modulators of metabotropic glutamate receptors
Marino, M. T., & Conn, P. J. (2005) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2005.09.006 · Cited by 111 · see citing works
Abdolahi, A., Acosta, G., Breslin, F. J., Hemby, S. E., & Lynch, W. J. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07114.x · Cited by 110 · see citing works
A conflict rat model of cue-induced relapse to cocaine seeking
Cooper, A., Barnea‐Ygael, N., Levy, D. J., Shaham, Y., & Zangen, A. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0827-7 · Cited by 105 · see citing works
Self-citationTime-dependent changes in alcohol-seeking behaviour during abstinence
Bieńkowski, P. (2004) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2003.10.005 · Cited by 103 · see citing works
Preclinical Determinants of Drug Choice under Concurrent Schedules of Drug Self-Administration
Banks, M. L., & Negus, S. S. (2012) · Advances in Pharmacological Sciences · doi:10.1155/2012/281768 · Cited by 100 · see citing works
Adewale, A. S., Platt, D. M., & Spealman, R. D. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.105387 · Cited by 89 · see citing works
Maintenance of reinforcement to address the chronic nature of drug addiction
Silverman, K., DeFulio, A., & Sigurdsson, S. O. (2012) · Preventive Medicine · doi:10.1016/j.ypmed.2012.03.013 · Cited by 86 · see citing works
Rodd, Z. A., McKinzie, D. L., Bell, R. L., McQueen, V. K., MURPHY, J., Schoepp, D. D., & McBride, W. J. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.03.032 · Cited by 86 · see citing works
Panlilio, L. V., Thorndike, E. B., & Schindler, C. W. (2003) · Psychopharmacology · doi:10.1007/s00213-002-1193-0 · Cited by 82 · see citing works
The runway model of drug self-administration
Ettenberg, A. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2008.11.003 · Cited by 82 · see citing works
Caprioli, D., Zeric, T., Thorndike, E. B., & Vènniro, M. (2015) · Addiction Biology · doi:10.1111/adb.12220 · Cited by 80 · see citing works
Self-citationDeroche‐Gamonet, V., & Piazza, P. V. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.07.014 · Cited by 79 · see citing works
Role of the Glutamatergic System in Nicotine Dependence
Liechti, M. E., & Markou, A. (2008) · CNS Drugs · doi:10.2165/00023210-200822090-00001 · Cited by 79 · see citing works
Jin, X., Semenova, S., Yang, L., Ardecky, R., Sheffler, D. J., Dahl, R. S., Conn, P. J., Cosford, N. D. P., & Markou, A. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.82 · Cited by 78 · see citing works
Bossert, J. M., Poles, G. C., Sheffler-Collins, S. I., & Ghitza, U. E. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.06.008 · Cited by 72 · see citing works
Self-citationQuick, S. L., Pyszczynski, A. D., Colston, K. A., & Shahan, T. A. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.239 · Cited by 69 · see citing works
Targeting cocaine versus heroin memories: divergent roles within ventromedial prefrontal cortex
Peters, J., Pattij, T., & Vries, T. J. D. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2013.10.004 · Cited by 68 · see citing works
Contingency management: an evidence‐based component of methamphetamine use disorder treatments
Roll, J. M. (2007) · Addiction · doi:10.1111/j.1360-0443.2006.01774.x · Cited by 68 · see citing works
Justinová, Z., Panlilio, L. V., Secci, M. E., Redhi, G. H., Schindler, C. W., Cross, A. J., Mrzljak, L., Medd, A. M., Shaham, Y., & Goldberg, S. R. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.01.014 · Cited by 63 · see citing works
Self-citationPelloux, Y., Murray, J. E., & Everitt, B. J. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3648-5 · Cited by 63 · see citing works
Substance-specific environmental influences on drug use and drug preference in animals and humans
Badiani, A. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.03.010 · Cited by 60 · see citing works
Ahmed, S. H. (2010) · Neuromethods · doi:10.1007/978-1-60761-934-5_10 · Cited by 57 · see citing works
Models of relapse and relapse prevention: A commentary.
Marlatt, G. A. (1996) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.4.1.55 · Cited by 56 · see citing works
Abstinence reinforcement maintenance contingency and one-year follow-up.
Preston, K., Umbricht, A., & Epstein, D. (2002) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(02)00023-6 · Cited by 52 · see citing works
Dhanya, R.-P., Sidique, S., Sheffler, D. J., Nickols, H. H., Herath, A., Yang, L., Dahl, R. S., Ardecky, R., Semenova, S., Markou, A., et al. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm1012165 · Cited by 52 · see citing works
Kufahl, P. R., Watterson, L. R., Nemirovsky, N. E., Hood, L. E., Villa, A., Halstengard, C., Zautra, N., & Olive, M. F. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.05.037 · Cited by 50 · see citing works
Crawford, J. T., Roberts, D. C. S., & Beveridge, T. J. R. (2013) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.07.024 · Cited by 39 · see citing works
Winterbauer, N. E., & Bouton, M. E. (2011) · Learning and Motivation · doi:10.1016/j.lmot.2011.01.002 · Cited by 35 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Scofield, M. D., Heinsbroek, J. A., Gipson, C. D., Kupchik, Y. M., Spencer, S., Smith, A. C. W., Roberts-Wolfe, D., & Kalivas, P. W. (2016) · Pharmacological Reviews · doi:10.1124/pr.116.012484 · Cited by 598 · see citing works
Synaptic mechanisms underlying persistent cocaine craving
Wolf, M. E. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2016.39 · Cited by 389 · see citing works
Volitional social interaction prevents drug addiction in rat models
Venniro, M., Zhang, M., Caprioli, D., Hoots, J. K., Golden, S. A., Heins, C., Morales, M., Epstein, D. H., & Shaham, Y. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0246-6 · Cited by 342 · see citing works
Self-citationAnimal models of drug relapse and craving
Vènniro, M., Caprioli, D., & Shaham, Y. (2015) · Progress in brain research · doi:10.1016/bs.pbr.2015.08.004 · Cited by 322 · see citing works
Self-citationTime to connect: bringing social context into addiction neuroscience
Heilig, M., Epstein, D. H., Nader, M. A., & Shaham, Y. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.67 · Cited by 298 · see citing works
Self-citationImproving translation of animal models of addiction and relapse by reverse translation
Venniro, M., Banks, M. L., Heilig, M., Epstein, D. H., & Shaham, Y. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-020-0378-z · Cited by 212 · see citing works
Self-citationCircuit and Synaptic Plasticity Mechanisms of Drug Relapse
Dong, Y., Taylor, J. R., Wolf, M. E., & Shaham, Y. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.1821-17.2017 · Cited by 170 · see citing works
Self-citationVenniro, M., Caprioli, D., Zhang, M., Whitaker, L. R., Zhang, S., Warren, B. L., Cifani, C., Marchant, N. J., Yizhar, O., Bossert, J. M., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.09.024 · Cited by 162 · see citing works
Self-citationVènniro, M., Zhang, M. H., Shaham, Y., & Caprioli, D. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.287 · Cited by 147 · see citing works
Self-citationSex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review
Nicolas, C., Zlebnik, N. E., Farokhnia, M., Leggio, L., Ikemoto, S., & Shaham, Y. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000367 · Cited by 144 · see citing works
Self-citationCaprioli, D., Vènniro, M., Zhang, M. H., Bossert, J. M., Warren, B. L., Hope, B. T., & Shaham, Y. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.3091-16.2016 · Cited by 143 · see citing works
Self-citationLi, X., Rubio, F. J., Zeric, T., Bossert, J. M., Kambhampati, S., Cates, H. M., Kennedy, P., Liu, Q., Cimbro, R., Hope, B. T., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.1022-15.2015 · Cited by 129 · see citing works
Self-citationRelapse to opioid seeking in rat models: behavior, pharmacology and circuits
Reiner, D. J., Fredriksson, I., Lofaro, O. M., Bossert, J. M., & Shaham, Y. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0234-2 · Cited by 131 · see citing works
Self-citationOperant Social Reward Decreases Incubation of Heroin Craving in Male and Female Rats
Venniro, M., Russell, T. I., Zhang, M., & Shaham, Y. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.05.018 · Cited by 127 · see citing works
Self-citationAnimal Models of (or for) Aggression Reward, Addiction, and Relapse: Behavior and Circuits
Golden, S. A., Jin, M., & Shaham, Y. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.0151-19.2019 · Cited by 121 · see citing works
Self-citationFebo, M., Blum, K., Badgaiyan, R. D., Pérez, P. D., Colón-Pérez, L. M., Thanos, P. K., Ferris, C. F., Kulkarni, P. P., Giordano, J., Baron, D. A., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0174774 · Cited by 105 · see citing works
Animal Models of Drug Relapse and Craving after Voluntary Abstinence: A Review
Fredriksson, I., Vènniro, M., Reiner, D. J., Chow, J. J., Bossert, J. M., & Shaham, Y. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000191 · Cited by 99 · see citing works
Self-citationAMPA Receptor Plasticity in Accumbens Core Contributes to Incubation of Methamphetamine Craving
Scheyer, A. F., Loweth, J. A., Christian, D., Uejima, J. L., Rabei, R., Le, T. Q., Dolubizno, H., Stefanik, M. T., Murray, C. H., Sakas, C., et al. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.04.003 · Cited by 98 · see citing works
An operant social self-administration and choice model in rats
Vènniro, M., & Shaham, Y. (2020) · Nature Protocols · doi:10.1038/s41596-020-0296-6 · Cited by 94 · see citing works
Self-citationCompulsive Addiction-like Aggressive Behavior in Mice
Golden, S. A., Heins, C., Vènniro, M., Caprioli, D., Zhang, M. H., Epstein, D. H., & Shaham, Y. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.03.004 · Cited by 93 · see citing works
Self-citationVènniro, M., Panlilio, L. V., Epstein, D. H., & Shaham, Y. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01148-6 · Cited by 92 · see citing works
Self-citationModeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms
Farrell, M. R., Schoch, H., & Mahler, S. V. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.01.002 · Cited by 85 · see citing works
How to study sex differences in addiction using animal models
Carroll, M. E., & Lynch, W. J. (2016) · Addiction Biology · doi:10.1111/adb.12400 · Cited by 82 · see citing works
Non-pharmacological factors that determine drug use and addiction
Ahmed, S. H., Badiani, A., Miczek, K. A., & Müller, C. P. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.08.015 · Cited by 83 · see citing works
Siemsen, B. M., Reichel, C. M., Leong, K.-C., García‐Keller, C., Gipson, C. D., Spencer, S. M., McFaddin, J. A., Hooker, K. N., Kalivas, P. W., & Scofield, M. D. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.03.040 · Cited by 81 · see citing works
Addictive behaviour in experimental animals: prospects for translation
Everitt, B. J., Giuliano, C., & Belin, D. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2017.0027 · Cited by 81 · see citing works
Trying to make sense of rodents' drug choice behavior
Ahmed, S. H. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.09.027 · Cited by 74 · see citing works
Reiner, D. J., Lofaro, O. M., Applebey, S. V., Korah, H. E., Vènniro, M., Cifani, C., Bossert, J. M., & Shaham, Y. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.2693-19.2020 · Cited by 70 · see citing works
Self-citationModeling the development of drug addiction in male and female animals
Lynch, W. J. (2017) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2017.06.006 · Cited by 70 · see citing works
Presynaptic G Protein-Coupled Receptors: Gatekeepers of Addiction?
Johnson, K. A., & Lovinger, D. M. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00264 · Cited by 66 · see citing works
Signals from the Fourth Dimension Regulate Drug Relapse
Mulholland, P. J., Chandler, L. J., & Kalivas, P. W. (2016) · Trends in Neurosciences · doi:10.1016/j.tins.2016.04.007 · Cited by 67 · see citing works
Vandaele, Y., Cantin, L., Serre, F., Vouillac‐Mendoza, C., & Ahmed, S. H. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.195 · Cited by 63 · see citing works
Abstinence-dependent dissociable central amygdala microcircuits control drug craving
Vènniro, M., Russell, T. I., Ramsey, L. A., Richie, C. T., Lesscher, H. M. B., Giovanetti, S. M., Messing, R. O., & Shaham, Y. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2001615117 · Cited by 65 · see citing works
Self-citationTranslational opportunities in animal and human models to study alcohol use disorder
Nieto, S. J., Grodin, E. N., Aguirre, C. G., Izquierdo, A., & Ray, L. A. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01615-0 · Cited by 64 · see citing works
Gregory, K. J., & Goudet, C. (2020) · Pharmacological Reviews · doi:10.1124/pr.119.019133 · Cited by 64 · see citing works
Justinová, Z., Panlilio, L. V., Secci, M. E., Redhi, G. H., Schindler, C. W., Cross, A. J., Mrzljak, L., Medd, A. M., Shaham, Y., & Goldberg, S. R. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.01.014 · Cited by 63 · see citing works
Self-citationFredriksson, I., Applebey, S. V., Minier-Toribio, A. M., Shekara, A., Bossert, J. M., & Shaham, Y. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0602-6 · Cited by 56 · see citing works
Self-citationGolden, S. A., Aleyasin, H., Heins, R., Flanigan, M. E., Heshmati, M., Takahashi, A., Russo, S. J., & Shaham, Y. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12310 · Cited by 58 · see citing works
Self-citationCaprioli, D., Justinova, Z., Venniro, M., & Shaham, Y. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.08.018 · Cited by 55 · see citing works
Self-citationFactors modulating the incubation of drug and non-drug craving and their clinical implications
Vènniro, M., Reverte, I., Ramsey, L. A., Papastrat, K. M., D’Ottavio, G., Milella, M. S., Li, X., Grimm, J. W., & Caprioli, D. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.09.050 · Cited by 58 · see citing works
Self-citationTargeting mGluR2/3 for treatment of neurodegenerative and neuropsychiatric diseases
Li, S. H., Abd‐Elrahman, K. S., & Ferguson, S. S. G. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108275 · Cited by 52 · see citing works
Oscillotherapeutics – Time-targeted interventions in epilepsy and beyond
Takeuchi, Y., & Berényi, A. (2020) · Neuroscience Research · doi:10.1016/j.neures.2020.01.002 · Cited by 51 · see citing works
Reprogramming of mPFC transcriptome and function in alcohol dependence
Heilig, M. A., Barbier, E., Johnstone, A. L., Tapocik, J. D., Meinhardt, M. W., Pfarr, S., Wahlestedt, C., & Sommer, W. H. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12344 · Cited by 50 · see citing works
Bossert, J. M., Hoots, J. K., Fredriksson, I., Adhikary, S., Zhang, M., Vènniro, M., & Shaham, Y. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.13955 · Cited by 49 · see citing works
Self-citationRole of Dorsal Striatum Histone Deacetylase 5 in Incubation of Methamphetamine Craving
Li, X., Carreria, M. B., Witonsky, K. R., Zeric, T., Lofaro, O. M., Bossert, J. M., Zhang, J., Surjono, F., Richie, C. T., Harvey, B. K., et al. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.12.008 · Cited by 48 · see citing works
Self-citationBernheim, A. P., Leong, K.-C., Berini, C., & Reichel, C. M. (2017) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2017.08.012 · Cited by 47 · see citing works
Kane, L. F., Vènniro, M., Quintana‐Feliciano, R., Madangopal, R., Rubio, F. J., Bossert, J. M., Caprioli, D., Shaham, Y., Hope, B. T., & Warren, B. L. (2020) · Addiction Biology · doi:10.1111/adb.12943 · Cited by 46 · see citing works
Self-citationNeurobiology of the incubation of drug craving: An update
Chow, J. J., Pitts, K. M., Negishi, K., Madangopal, R., Dong, Y., Wolf, M. E., & Shaham, Y. (2024) · Pharmacological Reviews · doi:10.1016/j.pharmr.2024.100022 · Cited by 45 · see citing works
Self-citationRage Against the Machine: Advancing the study of aggression ethology via machine learning.
Goodwin, N. L., Nilsson, S. R. O., & Golden, S. A. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05577-x · Cited by 43 · see citing works
Augier, E., Dulman, R. S., Rauffenbart, C., Augier, G., Cross, A. J., & Heilig, M. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.107 · Cited by 44 · see citing works
Chow, J. J., Beacher, N. J., Chabot, J. M., Oke, M., Vènniro, M., Lin, D., & Shaham, Y. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06064-1 · Cited by 44 · see citing works
Self-citationAdhikary, S., Caprioli, D., Vènniro, M., Kallenberger, P., Shaham, Y., & Bossert, J. M. (2016) · Addiction Biology · doi:10.1111/adb.12386 · Cited by 42 · see citing works
Self-citationLi, X., Witonsky, K. R., Lofaro, O. M., Surjono, F., Zhang, J., Bossert, J. M., & Shaham, Y. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.2873-17.2018 · Cited by 41 · see citing works
Self-citationRossi, L. M., Reverte, I., Ragozzino, D., Badiani, A., Vènniro, M., & Caprioli, D. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-019-0479-4 · Cited by 41 · see citing works
Self-citationD'Ottavio, G., Reverte, I., Ragozzino, D., Meringolo, M., Milella, M. S., Boix, F., Vènniro, M., Badiani, A., & Caprioli, D. (2022) · British Journal of Pharmacology · doi:10.1111/bph.15791 · Cited by 43 · see citing works
Self-citationAhmed, S. H. (2018) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2017.07.005 · Cited by 39 · see citing works
Fredriksson, I., Tsai, P.-J., Shekara, A., Duan, Y., Applebey, S. V., Lu, H., Bossert, J. M., Shaham, Y., & Yang, Y. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2106624118 · Cited by 39 · see citing works
Self-citationVènniro, M., Marino, R. A. M., Chow, J. J., Caprioli, D., Epstein, D. H., Ramsey, L. A., & Shaham, Y. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.0931-22.2022 · Cited by 38 · see citing works
Self-citationNovel models of drug relapse and craving after voluntary abstinence
Vènniro, M., Caprioli, D., & Shaham, Y. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0196-4 · Cited by 38 · see citing works
Self-citationNall, R. W., Craig, A. R., Browning, K. O., & Shahan, T. A. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.12.020 · Cited by 37 · see citing works
Role of orbitofrontal cortex in incubation of oxycodone craving in male rats
Altshuler, R. D., Yang, E. S., Garcia, K. T., Davis, I. R., Olaniran, A., Haile, M., Razavi, S., & Li, X. (2020) · Addiction Biology · doi:10.1111/adb.12927 · Cited by 37 · see citing works
Self-citationNeural mechanisms underlying incubation of methamphetamine craving: A mini-review
Altshuler, R. D., Lin, H., & Li, X. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.173058 · Cited by 37 · see citing works
Self-citationRoura‐Martínez, D., Ucha, M., Orihuel, J., Ballesteros‐Yáñez, I., Castillo, C. A., Marcos, A., Ambrosio, E., & Higuera‐Matas, A. (2019) · Addiction Biology · doi:10.1111/adb.12706 · Cited by 34 · see citing works
Rats choose alcohol over social reward in an operant choice procedure
Marchant, N. J., McDonald, A. J., Matsuzaki, R., van Mourik, Y., Schetters, D., & Vries, T. J. D. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01447-6 · Cited by 34 · see citing works
Self-citationFredriksson, I., Tsai, P.-J., Shekara, A., Duan, Y., Applebey, S. V., Minier-Toribio, A. M., Batista, A., Chow, J. J., Altidor, L., Barbier, E., et al. (2023) · Science Advances · doi:10.1126/sciadv.add8687 · Cited by 33 · see citing works
Self-citationDifferential Pharmacology and Binding of mGlu2 Receptor Allosteric Modulators
O’Brien, D. E., Shaw, D. M., Cho, H. P., Cross, A. J., Wesolowski, S. S., Felts, A. S., Bergare, J., Elmore, C. S., Lindsley, C. W., Niswender, C. M., et al. (2018) · Molecular Pharmacology · doi:10.1124/mol.117.110114 · Cited by 32 · see citing works
Camacho‐Morales, A., Montalvo-Martínez, L., Cárdenas-Pérez, R. E., Fuentes‐Mera, L., & Garza‐Ocañas, L. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.05.014 · Cited by 32 · see citing works
Bossert, J. M., Townsend, E. A., Altidor, L., Fredriksson, I., Shekara, A., Husbands, S. M., Sulima, A., Rice, K. C., Banks, M. L., & Shaham, Y. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15679 · Cited by 30 · see citing works
Self-citationMetabotropic Glutamate Receptor 2/3 as Targets for Treating Nicotine Addiction
Cross, A., Anthenelli, R., & Li, X. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.11.021 · Cited by 30 · see citing works
Self-citationCanchy, L., Girardeau, P., Durand, A., Vouillac‐Mendoza, C., & Ahmed, S. H. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0786-9 · Cited by 51 · see citing works
Sedighim, S., Carrette, L. L. G., Vènniro, M., Shaham, Y., de Guglielmo, G., & George, O. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05961-1 · Cited by 25 · see citing works
Self-citationGuerin, A. A., Nestler, E. J., Berk, M., Lawrence, A. J., Rossell, S. L., & Kim, J. H. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.11.001 · Cited by 30 · see citing works
Effects of alcohol dependence on discrete choice between alcohol and saccharin
Russo, M., Funk, D. R., Loughlin, A., Coen, K. M., & Lê, A. D. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0101-1 · Cited by 29 · see citing works
Wistar rats choose alcohol over social interaction in a discrete-choice model
Augier, G., Schwabl, V., Lguensat, A., Atudorei, M., Iyere, O. C., Solander, S. E., & Augier, E. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01526-8 · Cited by 26 · see citing works
Preventing incubation of drug craving to treat drug relapse: from bench to bedside
Liu, X., Yuan, K., Lu, T., Lin, X., Zheng, W., Xue, Y.-X., Shi, J., Lü, L., & Han, Y. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-01942-2 · Cited by 27 · see citing works
Fredriksson, I., Adhikary, S., Steensland, P., Vendruscolo, L. F., Bonci, A., Shaham, Y., & Bossert, J. M. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.209 · Cited by 27 · see citing works
Self-citationAugier, E. (2021) · Alcohol and Alcoholism · doi:10.1093/alcalc/agab003 · Cited by 27 · see citing works
Choice between delayed food and immediate oxycodone in rats
Secci, M. E., Factor, J., Schindler, C. W., & Panlilio, L. V. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4429-0 · Cited by 22 · see citing works
Extinction of conditioned cues attenuates incubation of cocaine craving in adolescent and adult rats
Madsen, H. B., Zbukvic, I., Luikinga, S. J., Lawrence, A. J., & Kim, J. H. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.09.002 · Cited by 24 · see citing works
Negus, S. S., & Banks, M. L. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-00815-4 · Cited by 24 · see citing works
mGlu5 function in the nucleus accumbens core during the incubation of methamphetamine craving
Murray, C. H., Christian, D., Milovanovic, M., Loweth, J. A., Hwang, E.-K., Caccamise, A. J., Funke, J. R., & Wolf, M. E. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108452 · Cited by 23 · see citing works
Neuronal representation of individual heroin choices in the orbitofrontal cortex
Guillem, K., Brenot, V., Durand, A., & Ahmed, S. H. (2017) · Addiction Biology · doi:10.1111/adb.12536 · Cited by 22 · see citing works
Campbell, E. J., Barker, D. J., Nasser, H. M., Kaganovsky, K., Dayas, C. V., & Marchant, N. J. (2017) · Behavioral Neuroscience · doi:10.1037/bne0000185 · Cited by 21 · see citing works
Self-citationPre-trial cocaine biases choice toward cocaine through suppression of the nondrug option
Freese, L., Durand, A., Guillem, K., & Ahmed, S. H. (2018) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2018.07.010 · Cited by 17 · see citing works
Hellyer, S. D., Leach, K., & Gregory, K. J. (2016) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2016.10.007 · Cited by 19 · see citing works
Johnson, K. A., & Lovinger, D. M. (2020) · Advances in pharmacology · doi:10.1016/bs.apha.2020.02.002 · Cited by 18 · see citing works
Bossert, J. M., Mejías-Aponte, C. A., Saunders, T. L., Altidor, L., Emery, M. A., Fredriksson, I., Batista, A., Claypool, S. M., Caldwell, K. E., Reiner, D. J., et al. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.2049-22.2023 · Cited by 18 · see citing works
Self-citationAcri, J. B., Cross, A. J., & Skolnick, P. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4501-9 · Cited by 17 · see citing works
Persistent vulnerability to relapse despite complete extinction of cocaine craving
Girardeau, P., Navailles, S., Durand, A., Vouillac‐Mendoza, C., Guillem, K., & Ahmed, S. H. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.05.036 · Cited by 16 · see citing works
Li, J., Jiang, W. A., Zhu, R., Fan, F., Fu, F., Wei, D., Tang, S., Tian, Y., Chen, J., Li, Y., et al. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.09.064 · Cited by 14 · see citing works
Relapse after electric barrier-induced voluntary abstinence: A review
Negishi, K., Fredriksson, I., Bossert, J. M., Zangen, A., & Shaham, Y. (2024) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2024.102856 · Cited by 15 · see citing works
Self-citationBusceti, C. L., Ginerete, R. P., Menna, L. D., D’Errico, G., Cisani, F., Pietro, P. D., Imbriglio, T., Bruno, V., Battaglia, G., Fornai, F., et al. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108692 · Cited by 15 · see citing works
Caprioli, D., Vènniro, M., Zhang, M. H., Bossert, J. M., Warren, B. L., Hope, B. T., & Shaham, Y. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3091-16.2017 · Cited by 14 · see citing works
Self-citationPreventing relapse after incentivized choice treatment: A laboratory model
Bouton, M. E., Thrailkill, E. A., Bergeria, C. L., & Davis, D. R. (2017) · Behavioural Processes · doi:10.1016/j.beproc.2017.02.005 · Cited by 14 · see citing works
Negishi, K., Duan, Y., Batista, A., Pishgar, M. S., Tsai, P.-J., Caldwell, K. E., Claypool, S. M., Reiner, D. J., Madangopal, R., Bossert, J. M., et al. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.0561-24.2025 · Cited by 13 · see citing works
Self-citationA mechanistic overview of approaches for the treatment of psychostimulant dependence
Jensen, K. L., Jensen, S. B., & Madsen, K. L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.854176 · Cited by 12 · see citing works
Nicolas, C., Russell, T. I., Shaham, Y., & Ikemoto, S. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.824741 · Cited by 12 · see citing works
Self-citationBlum, K., Marcelo, F., Dushaj, K., Fried, L., & Badgaiyan, R. D. (2016) · Journal of Systems and Integrative Neuroscience · doi:10.15761/jsin.1000129 · Cited by 12 · see citing works
Tuplin, E. W. N., Lightfoot, S. H. M., & Holahan, M. R. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00144 · Cited by 12 · see citing works
- Authors
- Caprioli, D., Venniro, M., Zeric, T., Li, X., Adhikary, S., Madangopal, R., Marchant, N. J., Lucantonio, F., Schoenbaum, G., Bossert, J. M., & Shaham, Y.
- Affiliations
- National Institutes of Health (US)
- Johns Hopkins University (US)
- Corresponding author
- Caprioli, Daniele
- ORCID
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2015-10
- Volume
- 78
- Issue
- 7
- Pages
- 463-473
- ISSN
- 0006-3223 (ISSN-L)
- PMC
- PMC4546920
- OpenAlex
- W2022691480
- Cited by
- 145
- References
- 88
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 9 · 2023: 6 · 2022: 14 · 2021: 16 · 2020: 19 · 2019: 6 · 2018: 20 · 2017: 21 · 2016: 20 · 2015: 5
- FWCI
- 10.22
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion, other-oa)
- Pure Amsterdam UMC (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- AstraZeneca
- National Institutes of Health
- Medical Research Council
- National Health and Medical Research Council (1053308)
- National Institute on Drug Abuse (ZIADA000434)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- incubation of craving, forced abstinence, mGluR2, positive allosteric modulators, relapse prevention, contingency management, extinction, self-administration
- MeSH terms
- Central Nervous System Stimulants, Animals, Cues, Disease Models, Animal, Extinction, Psychological, Food, Indoles, Methamphetamine, Oxadiazoles, Self Administration, Substance Withdrawal Syndrome, Time Factors, Volition, Receptors, Metabotropic Glutamate, Excitatory Amino Acid Agents, Amphetamine-Related Disorders, Rats, Drug-Seeking Behavior, Craving
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
