Cited by 20Sleep and Wakefulness ResearchNeural dynamics and brain functionMemory and Neural Mechanisms

Phase-locking of spontaneous and tone-elicited pontine waves to hippocampal theta waves during REM sleep in rats

Karashima, Akihiro, Katayama, Norihiro, Nakao, Mitsuyuki·2007·Brain Research

Abstract

Temporal relationships between hippocampal theta waves and pontine waves (P waves) during rapid-eye-movement (REM) sleep were investigated in rats. P waves were phase-locked to the positive theta peak. The phase relationships of P waves elicited by a tone stimulus (P(E) waves) to hippocampal theta waves were also analyzed to qualitatively clarify the mechanism of phase-locking between these two phenomena. P(E) waves occurred at the positive theta peak, as seen for spontaneous P waves. This phase preference of P(E) waves could be understood as that of the response probability to tone stimulus. These data suggest that the P-wave generator receives inputs that mimic theta waves. As hippocampal theta waves and P waves are known to be involved in learning and memory processes during REM sleep, the present studies could help to clarify these functions.

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Crossref · 10.1016/j.brainres.2007.08.060

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48 of 48 references verified0 citation errors · 0 not checkable

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  • Theta activity, i.e., periods of synchronized activity in the 4-8 Hz frequency band, is a hallmark of tonic REM sleep and correlates with rapid eye movements and PGO waves.

    “Theta activity, i.e., periods of synchronized activity in the 4 -8 Hz frequency band, is a hallmark of tonic REM sleep (REM sleep without actual rapid eye movements) (161) and correlates with rapid eye movements and PGO waves (618 -620).”

    From About Sleep's Role in Memory (2013) · cites this paper as [618]

  • PGO waves tend to occur phase-locked to theta oscillations.

    “PGO waves tend to occur phase-locked to theta oscillations (618).”

    From About Sleep's Role in Memory (2013) · cites this paper as [618]

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Authors
Karashima, A., Katayama, N., & Nakao, M.
Affiliations
Tohoku University (JP)
Corresponding author
Karashima, Akihiro
Venue
Brain Research
Publisher
Elsevier BV
Published
2007-11
Volume
1182
Pages
73-81
ISSN
0006-8993 (ISSN-L)
OpenAlex
W2067562916
Cited by
20
References
48
Citations by year
2026: 1 · 2025: 2 · 2023: 2 · 2022: 1 · 2021: 3 · 2019: 1 · 2015: 1 · 2014: 1 · 2013: 1 · 2012: 1
FWCI
1.00
Type
journal article
Language
en
Open access
closed
Locations
  • Brain Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
Japan Society for the Promotion of Science
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords
REM sleep, phase locking, rats
MeSH terms
Acoustic Stimulation, Animals, Hippocampus, Models, Biological, Pons, Probability, Reaction Time, Sleep, REM, Theta Rhythm, Rats, Sprague-Dawley, Rats

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