Cited by 79Neurobiology of Language and BilingualismReading and Literacy DevelopmentNeural and Behavioral Psychology Studies

Phonological working memory with auditory presentation of pseudo-words—an event related fMRI Study

Strand, Fredrik, Forssberg, Hans, Klingberg, Torkel, Norrelgen, Fritjof·2008·Brain Research

Abstract

Phonological working memory (PWM) tasks consist of a sequence of stimulus-encoding, maintenance and response. Few previous functional magnetic resonance imaging (fMRI) studies of PWM have employed event-related designs that make it possible to analyze the activations associated with each phase of such a task. The exploration of the cortical activation that takes place during the maintenance of PWM has been of particular interest to us. It has been suggested that temporary storage is served by the inferior parietal cortex. However, to the best of our knowledge earlier studies have used visual stimuli that might generate different cortical activations than auditory stimuli, which, presumably, would be more dependent on the auditory association cortex in the temporal lobe. This study involved an auditory stimulus presentation and a forced two-choice task. We used a parametric event-related design with fMRI. The stimuli consisted of pseudo-words of five, seven and nine syllables in length. In the control task, acoustically analogous stimuli without phonetic or linguistic content were used for passive listening. The left inferior frontal gyrus was activated during the stimulus-encoding, maintenance and response, in agreement with previous studies. However, in contrast to previous studies using visual presentation of verbal material, the inferior parietal cortex was not activated during the maintenance in the present study, but only active in the comparison and decision phase. Significant activation of the auditory cortex in the middle temporal gyrus was observed during the maintenance phase, which, together with the inferior frontal gyrus activation might underly the maintenance of phonological information.

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Crossref · 10.1016/j.brainres.2008.02.097

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Authors
Strand, F., Forssberg, H., Klingberg, T., & Norrelgen, F.
Affiliations
Karolinska Institutet (SE)
Venue
Brain Research
Publisher
Elsevier BV
Published
2008-05
Volume
1212
Pages
48-54
ISSN
0006-8993 (ISSN-L)
OpenAlex
W2033846968
Cited by
79
References
31
Citations by year
2026: 1 · 2025: 6 · 2024: 3 · 2023: 1 · 2022: 5 · 2021: 5 · 2020: 4 · 2019: 4 · 2018: 3 · 2017: 3 · 2016: 4 · 2015: 6 · 2014: 7 · 2013: 5 · 2012: 4
FWCI
3.10
Type
journal article
Language
en
Open access
closed
Locations
  • Brain Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
  • Social Sciences › Psychology › Developmental and Educational Psychology › Reading and Literacy Development
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
phonological working memory, auditory presentation, pseudowords, working memory maintenance, inferior parietal cortex, inferior frontal gyrus, middle temporal gyrus, auditory cortex, event-related design, syllable duration, passive listening
MeSH terms
Acoustic Stimulation, Adult, Brain Mapping, Cerebral Cortex, Choice Behavior, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Memory, Short-Term, Oxygen, Phonetics, Linear Models

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