The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies
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“Studies have identified inflammatory cytokines, including IL1β, IL6, and TNFα, are elevated in individuals and murine models with TET2 CH.”
From Clonal hematopoiesis related TET2 loss-of-function impedes IL1β-mediated epigenetic reprogramming in hematopoietic stem and progenitor cells (2023) · cites this paper as [9]
In the citing paper
“These studies suggest that inflammatory cytokines exert a selective pressure to drive the aberrant myeloid expansion of preleukemic cells in vivo7–9.”
From Clonal hematopoiesis related TET2 loss-of-function impedes IL1β-mediated epigenetic reprogramming in hematopoietic stem and progenitor cells (2023) · cites this paper as [9]
In the citing paper
“Inflammation is widely implicated in promoting the expansion of TET2-mediated clonal hematopoiesis and associated myeloid bias7–9,11; however, the mechanism is not completely defined.”
From Clonal hematopoiesis related TET2 loss-of-function impedes IL1β-mediated epigenetic reprogramming in hematopoietic stem and progenitor cells (2023) · cites this paper as [9]
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Citations
Cites
Mutation in TET2 in Myeloid Cancers
Delhommeau, F., Dupont, S., Valle, V. D., James, C., Trannoy, S., Massé, A., Kosmider, O., Le Couedic, J.-P., Robert, F., Alberdi, A., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810069 · Cited by 1,776
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
Moran-Crusio, K., Reavie, L., Shih, A., Abdel-Wahab, O., Ndiaye-Lobry, D., Lobry, C., Figueroa, M. E., Vasanthakumar, A., Patel, J., Zhao, X., et al. (2011) · Cancer Cell · doi:10.1016/j.ccr.2011.06.001 · Cited by 1,339
Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host
Meisel, M., Hinterleitner, R., Pacis, A., Chen, L., Earley, Z. M., Mayassi, T., Pierre, J. F., Ernest, J. D., Galipeau, H. J., Thuille, N., et al. (2018) · Nature · doi:10.1038/s41586-018-0125-z · Cited by 406
Cai, Z., Kotzin, J. J., Ramdas, B., Chen, S., Nelanuthala, S., Palam, L. R., Pandey, R., Mali, R. S., Liu, Y., Kelley, M. R., et al. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.10.013 · Cited by 394
Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota
Josefsdottir, K. S., Baldridge, M. T., Kadmon, C. S., & King, K. Y. (2017) · Blood · doi:10.1182/blood-2016-03-708594 · Cited by 343
Self-citationShih, A. H., Jiang, Y., Meydan, C., Shank, K., Pandey, S., Barreyro, L., Antony-Debre, I., Viale, A., Socci, N., Sun, Y., et al. (2015) · Cancer Cell · doi:10.1016/j.ccell.2015.03.009 · Cited by 236
Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells
Pan, F., Wingo, T. S., Zhao, Z., Gao, R., Makishima, H., Qu, G., Lin, L., Yu, M., Ortega, J. R., Wang, J., et al. (2017) · Nature Communications · doi:10.1038/ncomms15102 · Cited by 117
Mutation in TET2 in Myeloid Cancers
(2009) · New England Journal of Medicine · doi:10.1056/nejmc091348 · Cited by 66
Research works printed but not linked: 24
- Lemonnier, 2012, Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters, Blood, 120, 1466, 10.1182/blood-2012-02-408542 · DOI · Paper page
- Couronne, 2012, TET2 and DNMT3A mutations in human T-cell lymphoma, N. Engl. J. Med., 366, 95, 10.1056/NEJMc1111708 · DOI · Paper page
- Itzykson, 2013, Prognostic score including gene mutations in chronic myelomonocytic leukemia, J. Clin. Oncol., 31, 2428, 10.1200/JCO.2012.47.3314 · DOI
- Tefferi, 2009, Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML, Leukemia, 23, 1343, 10.1038/leu.2009.59 · DOI
- Grossmann, 2011, Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance, Leukemia, 25, 877, 10.1038/leu.2011.10 · DOI
- Quivoron, 2011, TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis, Cancer Cell, 20, 25, 10.1016/j.ccr.2011.06.003 · DOI · Paper page
- Chiba, 2017, Dysregulation of TET2 in hematologic malignancies, Int. J. Hematol., 105, 17, 10.1007/s12185-016-2122-z · DOI
- Busque, 2012, Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis, Nat. Genet., 44, 1179, 10.1038/ng.2413 · DOI · Paper page
- Ko, 2011, Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice, Proc. Natl. Acad. Sci. U. S. A., 108, 14566, 10.1073/pnas.1112317108 · DOI · Paper page
- Li, 2011, Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies, Blood, 118, 4509, 10.1182/blood-2010-12-325241 · DOI · Paper page
- Zhang, 2016, DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells, Nat. Genet., 48, 1014, 10.1038/ng.3610 · DOI · Paper page
- Zang, 2017, Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis, J. Clin. Investig., 127, 2998, 10.1172/JCI92026 · DOI
- Muto, 2013, Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders, J. Exp. Med., 210, 2627, 10.1084/jem.20131144 · DOI
- Cortes, 2018, RHOA G17V induces T Follicular helper cell specification and promotes lymphomagenesis, Cancer Cell, 33, 259, 10.1016/j.ccell.2018.01.001 · DOI · Paper page
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- King, 2011, Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response, Nat. Rev. Immunol., 11, 685, 10.1038/nri3062 · DOI · Paper page
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- Dalamaga, 2002, Risk factors for myelodysplastic syndromes: a case-control study in Greece, Cancer Causes Control, 13, 603
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- Khayr, 2012, Infections in hematological malignancies, Dis. Mon., 58, 239, 10.1016/j.disamonth.2012.01.001 · DOI
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- Abegunde, 2018, An inflammatory environment containing TNFalpha favors Tet2-mutant clonal hematopoiesis, Exp. Hematol., 59, 60, 10.1016/j.exphem.2017.11.002 · DOI · Paper page
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Cited by
Aging drives Tet2 +/− clonal hematopoiesis via IL-1 signaling
Caiado, F., Kovtonyuk, L. V., Gonullu, N. G., Fullin, J., Boettcher, S., & Manz, M. G. (2023) · Blood · doi:10.1182/blood.2022016835 · Cited by 161
Clonal hematopoiesis: Mutation-specific adaptation to environmental change
Florez, M. A., Tran, B. T., Wathan, T. K., DeGregori, J., Pietras, E. M., & King, K. Y. (2022) · Cell Stem Cell · doi:10.1016/j.stem.2022.05.006 · Cited by 129
Self-citationMcClatchy, J., Strogantsev, R., Wolfe, E., Lin, H. Y., Mohammadhosseini, M., Davis, B. A., Eden, C., Goldman, D., Fleming, W. H., Conley, P., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-43697-y · Cited by 95
Metadata
- Authors
- Zeng, H., He, H., Guo, L., Li, J., Lee, M., Han, W., Guzman, A. G., Zang, S., Zhou, Y., Zhang, X., Goodell, M. A., King, K. Y., Sun, D., & Huang, Y.
- Venue
- Cancer Letters
- Publisher
- Elsevier BV
- Published
- 2019-12
- Volume
- 467
- Pages
- 1-8
- ISSN
- 0304-3835
- PMC
- PMC6945766
- Cited by
- 38
- References
- 8
- Language
- en
- Funders
- National Institutes of Health
- American Cancer Society
- Welch Foundation
- John S. Dunn Foundation
- Cancer Prevention and Research Institute of Texas
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- CoChat. (2026). Citation check: Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies. https://app.cochat.ai/papers/10.1016/j.canlet.2019.09.013
- The paper
- Zeng, H., He, H., Guo, L., Li, J., Lee, M., Han, W., Guzman, A. G., Zang, S., Zhou, Y., Zhang, X., Goodell, M. A., King, K. Y., Sun, D., & Huang, Y. (2019). Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies. Cancer Letters. https://doi.org/10.1016/j.canlet.2019.09.013