Cited by 343Gut microbiota and healthHematopoietic Stem Cell TransplantationNeutropenia and Cancer Infections

Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota

Open access
Josefsdottir, Kamilla S., Baldridge, Megan T., Kadmon, Claudine S., King, Katherine Y.·2017·Blood

Abstract

Key Points: Antibiotics cause multilineage alterations in murine hematopoiesis, with marked suppression of multipotent progenitors. Suppression of bone marrow populations results from depletion of intestinal microbiota.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1182/blood-2016-03-708594

Cites

34 of 34 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The gut microbiota constantly communicates with vital organ systems of the host, such as the brain, bone marrow, vasculature, kidney, immune system and autonomic nervous system (ANS).

    “The gut microbiota constantly communicates with vital organ systems of the host, such as the brain6, bone marrow7, vasculature8, kidney9, immune system10 and autonomic nervous system (ANS)11,12.”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Josefsdottir, K. S., Baldridge, M. T., Kadmon, C. S., & King, K. Y.
Affiliations
  • Baylor College of Medicine (US)
  • Washington University in St. Louis (US)
Venue
Blood
Published
2017-02-09
Volume
129
Issue
6
Pages
729-739
ISSN
  • 0006-4971 (ISSN-L)
  • 1528-0020
OpenAlex
W2554797838
Cited by
343
References
34
Citations by year
2026: 25 · 2025: 42 · 2024: 46 · 2023: 31 · 2022: 50 · 2021: 43 · 2020: 40 · 2019: 30 · 2018: 25 · 2017: 11
FWCI
11.44
Type
journal article
Language
en
Open access
Locations
  • Blood (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • March of Dimes Foundation
  • Texas Children's Hospital
  • National Institutes of Health
  • National Cancer Institute (T32CA009547, P30CA125123)
  • National Institute of Allergy and Infectious Diseases (P30AI036211, R01AI141716, U19AI109725)
  • National Center for Research Resources (S10RR024574)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
  • Health Sciences › Medicine › Oncology › Neutropenia and Cancer Infections
Keywords
antibiotics, hematopoiesis, gut microbiota, fecal microbiota transplantation, germ-free mice, STAT1 signaling, T cell homeostasis, granulocyte maturation, myelosuppression
MeSH terms
Gastrointestinal Microbiome, Fecal Microbiota Transplantation, Anemia, Animals, Anti-Bacterial Agents, B-Lymphocytes, Bone Marrow Cells, Germ-Free Life, Granulocytes, Hematopoiesis, Hematopoietic Stem Cells, Leukopenia, Macrophages, Mice, Inbred C57BL, Thrombocytosis, Signal Transduction, Gene Expression, Mice, Knockout, CD8-Positive T-Lymphocytes, STAT1 Transcription Factor, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review