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Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae
Abstract
Recently, a great deal of interest has been developed to isolate novel bioactive compounds from marine resources because of their numerous health beneficial effects. Among marine resources, marine algae are valuable sources of structurally diverse bioactive compounds. The cell walls of marine algae are rich in sulfated polysaccharides (SPs) such as fucoidans in brown algae, carrageenans in red algae and ulvans in green algae. These SPs exhibit many beneficial biological activities such as anticoagulant, antiviral, antioxidative, anticancer and immunomodulating activities. Therefore, marine algae derived SPs have great potential for further development as products in nutraceutical, pharmaceutical and cosmeceutical areas. This contribution presents an overview of biological activities and potential health benefits of SPs derived from marine algae.
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“This research is necessary for the solution of problems of standardization of preparations on the basis of fucoidans, which have attracted attention as practically nontoxic natural products [25,26,27] with antitumor, immunomodulatory, and other useful properties [24,28,29,30].”
From Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects (2013) · cites this paper as [30]
In the citing paper
“Cancer preventive properties of fucoidans have been shown in many experiments.”
From Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects (2013) · cites this paper as [30]
In the citing paper
“For example, decrease of clonogenic growth of tumor cells was demonstrated after treatment with fucoidans [30,45,56].”
From Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects (2013) · cites this paper as [30]
In the citing paper
“These sulphate linked sugar units increased the inhibition of factors Xa, IIa and thrombin with the help of antithrombin and heparin cofactor II in blood coagulation intrinsic pathway”
From Polysaccharides from macroalgae: Recent advances, innovative technologies and challenges in extraction and purification (2017) · cites this paper as Wijesekara et al., 2011
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Functional Ingredients from Marine Algae as Potential Antioxidants in the Food Industry
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Seaweeds and Cancer Prevention
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Metadata
- Authors
- Wijesekara, I., Pangestuti, R., & Kim, S.-K.
- Affiliations
- Pukyong National University (KR)
- Corresponding author
- Kim, Se-Kwon
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2011-02
- Volume
- 84
- Issue
- 1
- Pages
- 14-21
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W2068498799
- Cited by
- 992
- References
- 126
- Citations by year
- 2026: 24 · 2025: 59 · 2024: 65 · 2023: 61 · 2022: 67 · 2021: 81 · 2020: 96 · 2019: 73 · 2018: 76 · 2017: 75 · 2016: 78 · 2015: 64 · 2014: 50 · 2013: 57 · 2012: 35
- FWCI
- 58.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Carbohydrate Polymers (publishedVersion)
- Funders
- Marine Bioprocess Research Center of the Marine Bio 21 Project
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- sulfated polysaccharides, marine algae, fucoidan, carrageenan, ulvan, anticoagulant activity, antiviral activity, antioxidant activity, anticancer activity, immunomodulation, nutraceuticals, pharmaceuticals, cosmeceuticals, bioactive compounds
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