The DOI matches its Crossref record; 148 of the 148 references it cites were found in a registry or an index.
Vascular NADPH oxidases: molecular mechanisms of activation
Abstract
Oxygen-derived free radicals are thought to contribute to the initiation and progression of cardiovascular disease via several different mechanisms, such as consumption of nitric oxide, oxidation of proteins and lipids, and activation of redox-sensitive signalling cascades. Vascular NADPH oxidases are important sources of vascular radical formation. The activities of these enzymes, which in some aspects are similar to the leukocyte NADPH oxidase, are controlled on the expression level and complex activation mechanisms. As a plethora of vascular stimuli, such as growth factors, cytokines, physical stimuli, and lipids elicits radical formation by these enzymes, a careful analysis is required for the understanding of the activation of the NADPH oxidases. This article reviews the components of the NADPH oxidases in leukocytes and vascular tissue. Emphasis is put on the activation of the oxidases, including upstream signalling events and molecular modes of interaction between the subunits.
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2 retracted
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RetractedThe phosphoinositide 3-kinase pathway
Cantley, L. C. (2002) · Science · doi:10.1126/science.296.5573.1655 · Cited by 5,621
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
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Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
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Cell transformation by the superoxide-generating oxidase Mox1
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Epidermal Growth Factor (EGF)-induced Generation of Hydrogen Peroxide
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Cited by
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
Bedard, K., & Krause, K.-H. (2007) · Physiological Reviews · doi:10.1152/physrev.00044.2005 · Cited by 6,989
“Several specialized reviews have been published recently (80, 102, 320, 636, 883).”
BackgroundRoles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis
Förstermann, U., Xia, N., & Li, H. (2017) · Circulation Research · doi:10.1161/circresaha.116.309326 · Cited by 1,519
Pacher, P., Nivorozhkin, A., & Szabó, C. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.1.6 · Cited by 1,218
NADPH oxidases: An overview from structure to innate immunity-associated pathologies
Panday, A., Sahoo, M. K., Osorio, D., & Batra, S. (2015) · Cellular & Molecular Immunology · doi:10.1038/cmi.2014.89 · Cited by 944
Role of microRNAs in vascular diseases, inflammation, and angiogenesis
Urbich, C., Kuehbacher, A., & Dimmeler, S. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn156 · Cited by 880
Metadata
- Authors
- BRANDES, R., & KREUZER, J.
- Venue
- Cardiovascular Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-01-01
- Volume
- 65
- Issue
- 1
- Pages
- 16-27
- ISSN
- 0008-6363 (ISSN-L)
- OpenAlex
- W2007981595
- Cited by
- 397
- References
- 148
- FWCI
- 13.68
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
