The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis

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The Autophagy Receptor Adaptor p62 is Up‐regulated by UVA Radiation in Melanocytes and in Melanoma Cells

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A Prognostic Bio-Model Based on SQSTM1 and N-Stage Identifies Nasopharyngeal Carcinoma Patients at High Risk of Metastasis for Additional Induction Chemotherapy

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PDCD4 inhibits lung tumorigenesis by the suppressing p62-Nrf2 signaling pathway and upregulating Keap1 expression.

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Epigenetic regulation of autophagy: A key modification in cancer cells and cancer stem cells

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Standard Immunohistochemical Assays to Assess Autophagy in Mammalian Tissue

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Sequestosome 1/p62-related pathways as therapeutic targets in hepatocellular carcinoma

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RANKL Signaling Sustains Primary Tumor Growth in Genetically Engineered Mouse Models of Lung Adenocarcinoma

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EGFR TKIs impair lysosome-dependent degradation of SQSTM1 to compromise the effectiveness in lung cancer

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Insight into the role of p62 in the cisplatin resistant mechanisms of ovarian cancer

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p62 participates in the inhibition of NF-κB signaling and apoptosis induced by sulfasalazine in human glioma U251 cells

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Knockdown of BNIP3L or SQSTM1 alters cellular response to mitochondria target drugs

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Targeting autophagy as a therapeutic strategy against pancreatic cancer

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Autophagy-related Proteins in Genome Stability: Autophagy-Dependent and Independent Actions

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The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ

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Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation

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Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy

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Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to ΔPK oncolytic activity in melanoma

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ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds.

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The prognostic value of p62 in solid tumor patients: a meta-analysis

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Acetylation of p62 regulates base excision repair through interaction with APE1

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p62 Binding to Protein Kinase C ζ Regulates Tumor Necrosis Factor α–Induced Apoptotic Pathway in Endothelial Cells

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Regulation of glucose metabolism by p62/SQSTM1 through HIF1α

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Proapoptotic and proautophagic activity of 20-hydroxyecdysone in breast cancer cells in vitro

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Inflammation in Primary and Metastatic Liver Tumorigenesis–Under the Influence of Alcohol and High-Fat Diets

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The caspase-6–p62 axis modulates p62 droplets based autophagy in a dominant-negative manner

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The suppressive effect of Rho kinase inhibitor, Y-27632, on oncogenic Ras/RhoA induced invasion/migration of human bladder cancer TSGH cells

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Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells

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p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation

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Structural and biochemical insights into the homotypic PB1-PB1 complex between PKCζ and p62

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p62/SQSTM1 is required for cell survival of apoptosis‐resistant bone metastatic prostate cancer cell lines

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Enhanced p62 expression triggers concomitant autophagy and apoptosis in a rat chronic spinal cord compression model

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Endoplasmic reticulum-Golgi intermediate compartment protein 3 knockdown suppresses lung cancer through endoplasmic reticulum stress-induced autophagy

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Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1

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Sulindac‐derived retinoid X receptor‐α modulator attenuates atherosclerotic plaque progression and destabilization in ApoE−/− mice

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3-Decylcatechol induces autophagy-mediated cell death through the IRE1α/JNK/p62 in hepatocellular carcinoma cells

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Natural agents mediated autophagic signal networks in cancer

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Role of PARP1-mediated autophagy in EGFR-TKI resistance in non-small cell lung cancer

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Targeting receptor activator of nuclear factor-kappa B as a new therapy for bone metastasis in non-small cell lung cancer

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Behavioral effects of SQSTM1/p62 overexpression in mice: Support for a mitochondrial role in depression and anxiety

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Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis

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Inhibition of miR-191 contributes to radiation-resistance of two lung cancer cell lines by altering autophagy activity

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The expression of p‐p62 and nuclear Nrf2 in esophageal squamous cell carcinoma and association with radioresistance

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NF-kappa B Signaling-Related Signatures Are Connected with the Mesenchymal Phenotype of Circulating Tumor Cells in Non-Metastatic Breast Cancer

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Inhibitory effect of penta-acetyl geniposide on C6 glioma cells metastasis by inhibiting matrix metalloproteinase-2 expression involved in both the PI3K and ERK signaling pathways

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Effect of p62 on tau hyperphosphorylation in a rat model of Alzheimer's disease.

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QSOX1 Inhibits Autophagic Flux in Breast Cancer Cells

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Identification of an IKKβ inhibitor for inhibition of inflammation in vivo and in vitro

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Identification of an autophagy-related gene signature that can improve prognosis of hepatocellular carcinoma patients

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Protective effects of pioglitazone in renal ischemia–reperfusion injury (RIRI): focus on oxidative stress and inflammation

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p62 functions as a signal hub in metal carcinogenesis

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NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ

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Involvement of kinase PKC-zeta in the p62/p62P392L-driven activation of NF-κB in human osteoclasts

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LIMD1 is induced by and required for LMP1 signaling, and protects EBV-transformed cells from DNA damage-induced cell death

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Triclosan Enhances the Clearing of Pathogenic Intracellular Salmonella or Candida albicans but Disturbs the Intestinal Microbiota through mTOR-Independent Autophagy

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Role of Autophagy in Cancer and Tumor Progression

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Identification of nasopharyngeal carcinoma metastasis-related biomarkers by iTRAQ combined with 2D-LC-MS/MS

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aPKC in neuronal differentiation, maturation and function

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TRAF6-mediated ubiquitination of MST1/STK4 attenuates the TLR4-NF-κB signaling pathway in macrophages

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A glutathione-responsive silica-based nanosystem capped with in-situ polymerized cell-penetrating poly(disulfide)s for precisely modulating immuno-inflammatory responses

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Recent Insights into the Biomarkers, Molecular Targets and Mechanisms of Non-Alcoholic Steatohepatitis-Driven Hepatocarcinogenesis

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Melatonin‐mediated regulation of autophagy: Making sense of double‐edged sword in cancer

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p62 Negatively Regulates TLR4 Signaling via Functional Regulation of the TRAF6-ECSIT Complex

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The essential and downstream common proteins of amyotrophic lateral sclerosis: A protein-protein interaction network analysis

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Autophagy in Viral Development and Progression of Cancer

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AKR1C1 connects autophagy and oxidative stress by interacting with SQSTM1 in a catalytic-independent manner

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Intestinal antiviral signaling is controlled by autophagy gene Epg5 independent of the microbiota

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Autophagy and cancer metabolism—The two‐way interplay

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Nrf2 and Parkin-Hsc70 regulate the expression and protein stability of p62/SQSTM1 under hypoxia

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KLF7 promotes adipocyte inflammation and glucose metabolism disorder by activating the PKCζ / NF‐κB pathway

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Characterization of two types of intranuclear hepatocellular inclusions in NAFLD

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Autophagy hub-protein p62 orchestrates oxidative, endoplasmic reticulum stress, and inflammatory responses post-ischemia, exacerbating stroke outcome

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The protease inhibitor E64d improves ox-LDL-induced endothelial dysfunction in human aortic endothelial cells

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The macroenviromental control of cancer metabolism by p62

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P62 deficiency shifts mesenchymal/stromal stem cell commitment toward adipogenesis and disrupts bone marrow homeostasis in aged mice

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Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells

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