Mosaic Analysis with Double Markers in Mice

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

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Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein

Shaner, N. C., Campbell, R. E., Steinbach, P. A., Giepmans, B. N. G., Palmer, A. E., & Tsien, R. Y. (2004) · Nature Biotechnology · doi:10.1038/nbt1037 · Cited by 4,619

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

Gong, S., Zheng, C., Doughty, M. L., Losos, K., Didkovsky, N., Schambra, U. B., Nowak, N. J., Joyner, A., Leblanc, G., Hatten, M. E., et al. (2003) · Nature · doi:10.1038/nature02033 · Cited by 2,108

The knockout mouse project

The Comprehensive Knockout Mouse Project Consortium (2004) · Nature Genetics · doi:10.1038/ng0904-921 · Cited by 608

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

Madisen, L., Zwingman, T. A., Sunkin, S. M., Oh, S. W., Zariwala, H. A., Gu, H., Ng, L. L., Palmiter, R. D., Hawrylycz, M. J., Jones, A. R., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2467 · Cited by 6,907

A global double-fluorescent Cre reporter mouse

Muzumdar, M. D., Tasic, B., Miyamichi, K., Li, L., & Luo, L. (2007) · genesis · doi:10.1002/dvg.20335 · Cited by 3,491

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

Ming, G.-L., & Song, H. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.001 · Cited by 2,651

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system

Livet, J., Weissman, T. A., Kang, H., Draft, R. W., Lu, J., Bennis, R. A., Sanes, J. R., & Lichtman, J. W. (2007) · Nature · doi:10.1038/nature06293 · Cited by 1,876

In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics

Bonaguidi, M. A., Wheeler, M. A., Shapiro, J. S., Stadel, R. P., Sun, G. J., Ming, G.-L., & Song, H. (2011) · Cell · doi:10.1016/j.cell.2011.05.024 · Cited by 831

Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

Wanner, I. B., Anderson, M. A., Song, B., Levine, J., Fernandez, A., Gray-Thompson, Z., Ao, Y., & Sofroniew, M. V. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2121-13.2013 · Cited by 839

Targeting cells with single vectors using multiple-feature Boolean logic

Fenno, L. E., Mattis, J., Ramakrishnan, C., Hyun, M., Lee, S. Y., He, M., Tucciarone, J., Selimbeyoglu, A., Berndt, A., Grosenick, L., et al. (2014) · Nature Methods · doi:10.1038/nmeth.2996 · Cited by 557

Distinct behavioural and network correlates of two interneuron types in prefrontal cortex

Kvitsiani, D., Ranade, S., Hangya, B., Taniguchi, H., Huang, J. Z., & Kepecs, A. (2013) · Nature · doi:10.1038/nature12176 · Cited by 516

Genetic Fate Mapping Reveals That the Caudal Ganglionic Eminence Produces a Large and Diverse Population of Superficial Cortical Interneurons

Miyoshi, G., Hjerling-Leffler, J., Karayannis, T., Sousa, V. H., Butt, S. J. B., Battiste, J., Johnson, J. E., Machold, R. P., & Fishell, G. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4515-09.2010 · Cited by 559

Development of a Method for the Purification and Culture of Rodent Astrocytes

Foo, L. C., Allen, N. J., Bushong, E. A., Ventura, P. B., Chung, W.-S., Zhou, L., Cahoy, J. D., Daneman, R., Zong, H., Ellisman, M. H., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.07.022 · Cited by 433

Architectures of neuronal circuits

Luo, L. (2021) · Science · doi:10.1126/science.abg7285 · Cited by 390

Single-Cell Transcriptomics Meets Lineage Tracing

Kester, L., & van Oudenaarden, A. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.04.014 · Cited by 375

Microbiota controls the homeostasis of glial cells in the gut lamina propria

Kabouridis, P. S., Lasrado, R., McCallum, S., Chng, S. H., Snippert, H. J., Clevers, H., Pettersson, S., & Pachnis, V. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.037 · Cited by 358

Building a lineage from single cells: genetic techniques for cell lineage tracking

Woodworth, M. B., Girskis, K. M., & Walsh, C. A. (2017) · Nature Reviews Genetics · doi:10.1038/nrg.2016.159 · Cited by 236

Site-specific integrase-mediated transgenesis in mice via pronuclear injection

Tasic, B., Hippenmeyer, S., Wang, C., Gamboa, M., Zong, H., Chen-Tsai, Y., & Luo, L. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019507108 · Cited by 246

All β Cells Contribute Equally to Islet Growth and Maintenance

Brennand, K., Huangfu, D., & Melton, D. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050163 · Cited by 210

Depolarizing effect of neocortical chandelier neurons

Woodruff, A. (2009) · Frontiers in Neural Circuits · doi:10.3389/neuro.04.015.2009 · Cited by 163

Current issues in mouse genome engineering

Glaser, S., Anastassiadis, K., & Stewart, A. F. (2005) · Nature Genetics · doi:10.1038/ng1668 · Cited by 160

Brainbow: New Resources and Emerging Biological Applications for Multicolor Genetic Labeling and Analysis

Weissman, T. A., & Pan, Y. A. (2015) · Genetics · doi:10.1534/genetics.114.172510 · Cited by 153

Single-neuron labeling with inducible Cre-mediated knockout in transgenic mice

Young, P., Qiu, L., Wang, D., Zhao, S., Gross, J., & Feng, G. (2008) · Nature Neuroscience · doi:10.1038/nn.2118 · Cited by 152

Clonally related forebrain interneurons disperse broadly across both functional areas and structural boundaries

Mayer, C., Jaglin, X. H., Cobbs, L. V., Bandler, R. C., Streicher, C., Cepko, C. L., Hippenmeyer, S., & Fishell, G. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.011 · Cited by 113

Tracing oncogene-driven remodelling of the intestinal stem cell niche

Yum, M. K., Han, S., Fink, J., Wu, S.-H. S., Dabrowska, C., Trendafilova, T., Mustata, R., Chatzeli, L., Azzarelli, R., Pshenichnaya, I., et al. (2021) · Nature · doi:10.1038/s41586-021-03605-0 · Cited by 114

Mapping cell fate and function using recombinase-based intersectional strategies

Dymecki, S. M., Ray, R. S., & Kim, J. C. (2010) · Methods in Enzymology · doi:10.1016/s0076-6879(10)77011-7 · Cited by 104

Cellular origin of glioblastoma and its implication in precision therapy

Yao, M., Li, S., Wu, X., Diao, S., Zhang, G., He, H., Bian, L., & Lu, Y. (2018) · Cellular & Molecular Immunology · doi:10.1038/cmi.2017.159 · Cited by 94

Distinct Lineage-Dependent Structural and Functional Organization of the Hippocampus

Xu, H.-T., Han, Z., Gao, P., He, S., Li, Z., Shi, W., Kodish, O., Shao, W., Brown, K. N., Huang, K., et al. (2014) · Cell · doi:10.1016/j.cell.2014.03.067 · Cited by 80

Radial glial cells in the adult dentate gyrus: what are they and where do they come from?

Berg, D. A., Bond, A. M., Ming, G.-L., & Song, H. (2018) · F1000Research · doi:10.12688/f1000research.12684.1 · Cited by 89

SPARC enables genetic manipulation of precise proportions of cells

Isaacman-Beck, J., Paik, K. C., Wienecke, C. F. R., Yang, H. H., Fisher, Y. E., Wang, I. E., Ishida, I. G., Maimon, G., Wilson, R. I., & Clandinin, T. R. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-0668-9 · Cited by 77

Molecular genetics and imaging technologies for circuit-based neuroanatomy

Arenkiel, B. R., & Ehlers, M. D. (2009) · Nature · doi:10.1038/nature08536 · Cited by 78

Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers

Muzumdar, M. D., Dorans, K. J., Chung, K. M., Robbins, R., Tammela, T., Gocheva, V., Li, C. M.-C., & Jacks, T. (2016) · Nature Communications · doi:10.1038/ncomms12685 · Cited by 72

Large neutral amino acid levels tune perinatal neuronal excitability and survival

Knaus, L. S., Basilico, B., Malzl, D., Gerykova Bujalkova, M., Smogavec, M., Schwarz, L. A., Gorkiewicz, S., Amberg, N., Pauler, F. M., Knittl-Frank, C., et al. (2023) · Cell · doi:10.1016/j.cell.2023.02.037 · Cited by 70

In situ cell-type-specific cell-surface proteomic profiling in mice

Shuster, S. A., Li, J., Chon, U., Sinantha-Hu, M. C., Luginbuhl, D. J., Udeshi, N. D., Carey, D. K., Takeo, Y. H., Xie, Q., Xu, C., et al. (2022) · Neuron · doi:10.1016/j.neuron.2022.09.025 · Cited by 70

Extensions of MADM (mosaic analysis with double markers) in mice

Tasic, B., Miyamichi, K., Hippenmeyer, S., Dani, V. S., Zeng, H., Joo, W., Zong, H., Chen-Tsai, Y., & Luo, L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033332 · Cited by 63

Essentials of Recombinase-Based Genetic Fate Mapping in Mice

Jensen, P., & Dymecki, S. M. (2014) · Methods in Molecular Biology · doi:10.1007/978-1-60327-292-6_26 · Cited by 54

iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications

Fernández-Chacón, M., Casquero-García, V., Luo, W., Francesca Lunella, F., Ferreira Rocha, S., Del Olmo-Cabrera, S., & Benedito, R. (2019) · Nature Communications · doi:10.1038/s41467-019-10239-4 · Cited by 54

Impaired cortical neurogenesis in plexin‐B 1 and ‐B 2 double deletion mutant

Daviaud, N., Chen, K., Huang, Y., Friedel, R. H., & Zou, H. (2016) · Developmental Neurobiology · doi:10.1002/dneu.22364 · Cited by 35

Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs

Henderson, N. T., Le Marchand, S. J., Hruska, M., Hippenmeyer, S., Luo, L., & Dalva, M. B. (2019) · eLife · doi:10.7554/elife.41563 · Cited by 15

Morphological pseudotime ordering and fate mapping reveals diversification of cerebellar inhibitory interneurons

Wang, W. X., & Lefebvre, J. L. (2020) · doi:10.1101/2020.02.29.971366