Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

Neurogenesis in the adult human hippocampus

Eriksson, P. S., Perfilieva, E., Björk-Eriksson, T., Alborn, A.-M., Nordborg, C., Peterson, D. A., & Gage, F. H. (1998) · Nature Medicine · doi:10.1038/3305 · Cited by 6,369 · see citing works

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

Reynolds, B. A., & Weiss, S. (1992) · Science · doi:10.1126/science.1553558 · Cited by 5,413 · see citing works

Mammalian neural stem cells.

Gage, F. H. (2000) · Science · doi:10.1126/science.287.5457.1433 · Cited by 3,949 · see citing works

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898 · see citing works

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

van Praag, H., Kempermann, G., & Gage, F. H. (1999) · Nature Neuroscience · doi:10.1038/6368 · Cited by 3,880 · see citing works

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

Altman, J., & Das, G. D. (1965) · Journal of Comparative Neurology · doi:10.1002/cne.901240303 · Cited by 3,592 · see citing works

More hippocampal neurons in adult mice living in an enriched environment

Kempermann, G., Kuhn, H. G., & Gage, F. H. (1997) · Nature · doi:10.1038/386493a0 · Cited by 3,513 · see citing works

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

Kuhn, H., Dickinson-Anson, H., & Gage, F. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-06-02027.1996 · Cited by 3,139 · see citing works

Mechanisms and Functional Implications of Adult Neurogenesis

Zhao, C., Deng, W., & Gage, F. H. (2008) · Cell · doi:10.1016/j.cell.2008.01.033 · Cited by 3,007 · see citing works

Functional neurogenesis in the adult hippocampus

van Praag, H., Schinder, A. F., Christie, B. R., Toni, N., Palmer, T. D., & Gage, F. H. (2002) · Nature · doi:10.1038/4151030a · Cited by 2,853 · see citing works

Neuronal replacement from endogenous precursors in the adult brain after stroke

Arvidsson, A., Collin, T., Kirik, D., Kokaia, Z., & Lindvall, O. (2002) · Nature Medicine · doi:10.1038/nm747 · Cited by 2,799 · see citing works

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

Monje, M. L., Toda, H., & Palmer, T. D. (2003) · Science · doi:10.1126/science.1088417 · Cited by 2,426 · see citing works

The relationship between the spleen colony-forming cell and the haemopoietic stem cell.

Schofield, R. (1978) · PubMed · Cited by 2,319 · see citing works

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

Deng, W., Aimone, J. B., & Gage, F. H. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2822 · Cited by 2,120 · see citing works

Neurons derived from radial glial cells establish radial units in neocortex

Noctor, S. C., Flint, A. C., Weissman, T. A., Dammerman, R. S., & Kriegstein, A. R. (2001) · Nature · doi:10.1038/35055553 · Cited by 2,016 · see citing works

Neurogenesis in the adult is involved in the formation of trace memories

Shors, T. J., Miesegaes, G. R., Beylin, A. V., Zhao, M., Rydel, T. A., & Gould, E. (2001) · Nature · doi:10.1038/35066584 · Cited by 2,014 · see citing works

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

Snippert, H. J., van der Flier, L. G., Sato, T., van Es, J. H., van den Born, M., Kroon-Veenboer, C., Barker, N., Klein, A. M., van Rheenen, J., Simons, B. D., et al. (2010) · Cell · doi:10.1016/j.cell.2010.09.016 · Cited by 1,951 · see citing works

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

Morrison, S. J., & Spradling, A. C. (2008) · Cell · doi:10.1016/j.cell.2008.01.038 · Cited by 1,951 · see citing works

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system

Livet, J., Weissman, T. A., Kang, H., Draft, R. W., Lu, J., Bennis, R. A., Sanes, J. R., & Lichtman, J. W. (2007) · Nature · doi:10.1038/nature06293 · Cited by 1,876 · see citing works

Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus

Parent, J. M., Yu, T. W., Leibowitz, R. T., Geschwind, D. H., Sloviter, R. S., & Lowenstein, D. H. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-10-03727.1997 · Cited by 1,853 · see citing works

ADULT NEUROGENESIS IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM

Ming, G., & Song, H. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.28.051804.101459 · Cited by 1,829 · see citing works

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

Sierra, A., Encinas, J. M., Deudero, J. J. P., Chancey, J. H., Enikolopov, G., Overstreet-Wadiche, L. S., Tsirka, S. E., & Maletic-Savatic, M. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.08.014 · Cited by 1,622 · see citing works

Wnt signalling regulates adult hippocampal neurogenesis

Lie, D. C., Colamarino, S. A., Song, H., Désiré, L., Mira, H., Consiglio, A., Lein, E. S., Jessberger, S., Lansford, H., Dearie, A. R., et al. (2005) · Nature · doi:10.1038/nature04108 · Cited by 1,510 · see citing works

Astrocytes give rise to new neurons in the adult mammalian hippocampus

Seri, B., Garcı́a-Verdugo, J. M., McEwen, B. S., & Alvarez-Buylla, A. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-18-07153.2001 · Cited by 1,495 · see citing works

Astroglia induce neurogenesis from adult neural stem cells

Song, H., Stevens, C. F., & Gage, F. H. (2002) · Nature · doi:10.1038/417039a · Cited by 1,452 · see citing works

Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells

Morshead, C. M., Reynolds, B. A., Craig, C. G., McBurney, M. W., Staines, W. A., Morassutti, D., Weiss, S., & van der Kooy, D. (1994) · Neuron · doi:10.1016/0896-6273(94)90046-9 · Cited by 1,403 · see citing works

Neurogenic radial glia in the outer subventricular zone of human neocortex

Hansen, D. V., Lui, J. H., Parker, P. R. L., & Kriegstein, A. R. (2010) · Nature · doi:10.1038/nature08845 · Cited by 1,388 · see citing works

Adult neurogenesis and functional plasticity in neuronal circuits

Lledo, P., Alonso, M., & Grubb, M. S. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn1867 · Cited by 1,364 · see citing works

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

Guo, J. U., Su, Y., Zhong, C., Ming, G., & Song, H. (2011) · Cell · doi:10.1016/j.cell.2011.03.022 · Cited by 1,355 · see citing works

Chain Migration of Neuronal Precursors

Lois, C., García-Verdugo, J.-M., & Alvarez-Buylla, A. (1996) · Science · doi:10.1126/science.271.5251.978 · Cited by 1,331 · see citing works

Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration

Sanai, N., Tramontin, A. D., Quiñones‐Hinojosa, A., Barbaro, N. M., Gupta, N. M., Kunwar, S., Lawton, M. T., McDermott, M. W., Parsa, A. T., García‐Verdugo, J. M., et al. (2004) · Nature · doi:10.1038/nature02301 · Cited by 1,315 · see citing works

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

Molofsky, A. V., Pardal, R., Iwashita, T., Park, I.-K., Clarke, M. F., & Morrison, S. J. (2003) · Nature · doi:10.1038/nature02060 · Cited by 1,301 · see citing works

Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus

Schmidt-Hieber, C., Jonas, P., & Bischofberger, J. (2004) · Nature · doi:10.1038/nature02553 · Cited by 1,292 · see citing works

GABA regulates synaptic integration of newly generated neurons in the adult brain

Ge, S., Goh, E. L. K., Sailor, K. A., Kitabatake, Y., Ming, G., & Song, H. (2005) · Nature · doi:10.1038/nature04404 · Cited by 1,261 · see citing works

Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus

Zhao, C., Teng, E. M., Summers, R. G., Ming, G.-L., & Gage, F. H. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.3648-05.2006 · Cited by 1,257 · see citing works

Coexistence of Quiescent and Active Adult Stem Cells in Mammals

Li, L., & Clevers, H. (2010) · Science · doi:10.1126/science.1180794 · Cited by 1,247 · see citing works

STEM CELL NICHE: Structure and Function

Li, L., & Xie, T. (2005) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.012704.131525 · Cited by 1,228 · see citing works

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

Ziv, Y., Ron, N., Butovsky, O., Landa, G., Sudai, E., Greenberg, N., Cohen, H., Kipnis, J., & Schwartz, M. (2006) · Nature Neuroscience · doi:10.1038/nn1629 · Cited by 1,209 · see citing works

Adult hippocampal neurogenesis in depression

Sahay, A., & Hen, R. (2007) · Nature Neuroscience · doi:10.1038/nn1969 · Cited by 1,206 · see citing works

A translational profiling approach for the molecular characterization of CNS cell types

Heiman, M., Schaefer, A., Gong, S., Peterson, J. D., Day, M., Ramsey, K. E., Suárez-Fariñas, M., Schwarz, C., Stephan, D. A., Surmeier, D. J., et al. (2008) · Cell · doi:10.1016/j.cell.2008.10.028 · Cited by 1,134 · see citing works

Noggin Antagonizes BMP Signaling to Create a Niche for Adult Neurogenesis

Lim, D. A., Tramontin, A. D., Trevejo, J., Herrera, D. G., García‐Verdugo, J. M., & Álvarez-Buylla, A. (2000) · Neuron · doi:10.1016/s0896-6273(00)00148-3 · Cited by 1,090 · see citing works

EGF Converts Transit-Amplifying Neurogenic Precursors in the Adult Brain into Multipotent Stem Cells

Doetsch, F. K., Petreanu, L., Caillé, I., García‐Verdugo, J. M., & Álvarez-Buylla, A. (2002) · Neuron · doi:10.1016/s0896-6273(02)01133-9 · Cited by 1,048 · see citing works

A specialized vascular niche for adult neural stem cells

Tavazoie, M., Van der Veken, L., Silva-Vargas, V., Louissaint, M., Colonna, L., Zaidi, B., Garcia-Verdugo, J. M., & Doetsch, F. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.025 · Cited by 1,033 · see citing works

Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions

Shen, Q., Wang, Y., Kokovay, E., Lin, G., Chuang, S.-M., Goderie, S. K., Roysam, B., & Temple, S. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.026 · Cited by 1,027 · see citing works

Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain

Mirzadeh, Z., Merkle, F. T., Soriano-Navarro, M., Garcia-Verdugo, J. M., & Alvarez-Buylla, A. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.004 · Cited by 1,015 · see citing works

Neuronal Activity–Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

Dengke, K., Jang, M., Guo, J. U., Kitabatake, Y., Chang, M.-L., Pow-anpongkul, N., Flavell, R. A., Lu, B., Ming, G., & Song, H. (2009) · Science · doi:10.1126/science.1166859 · Cited by 929 · see citing works

A Critical Period for Enhanced Synaptic Plasticity in Newly Generated Neurons of the Adult Brain

Ge, S., Yang, C.-H., Hsu, K.-S., Ming, G.-L., & Song, H. (2007) · Neuron · doi:10.1016/j.neuron.2007.05.002 · Cited by 927 · see citing works

Fibroblast Growth Factor-2 Activates a Latent Neurogenic Program in Neural Stem Cells from Diverse Regions of the Adult CNS

Palmer, T. D., Markakis, E. A., Willhoite, A. R., Safar, F., & Gage, F. H. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-19-08487.1999 · Cited by 909 · see citing works

Stems Cells and the Pathways to Aging and Cancer

Rossi, D. J., Jamieson, C. H. M., & Weissman, I. L. (2008) · Cell · doi:10.1016/j.cell.2008.01.036 · Cited by 895 · see citing works

Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension

Curtis, M. A., Kam, M., Nannmark, U., Anderson, M. F., Axell, M. Z., Wikkelsø, C., Holtås, S., van Roon‐Mom, W., Björk‐Eriksson, T., Nordborg, C., et al. (2007) · Science · doi:10.1126/science.1136281 · Cited by 887 · see citing works

Oligodendrocyte Precursor Cells Reprogrammed to Become Multipotential CNS Stem Cells

Kondo, T., & RAFF, M. C. (2000) · Science · doi:10.1126/science.289.5485.1754 · Cited by 880 · see citing works

Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus

Kee, N., Teixeira, C. M., Wang, A. H., & Frankland, P. W. (2007) · Nature Neuroscience · doi:10.1038/nn1847 · Cited by 875 · see citing works

Mosaic Organization of Neural Stem Cells in the Adult Brain

Merkle, F. T., Mirzadeh, Z., & Álvarez-Buylla, A. (2007) · Science · doi:10.1126/science.1144914 · Cited by 821 · see citing works

In Vivo Fate Analysis Reveals the Multipotent and Self-Renewal Capacities of Sox2+ Neural Stem Cells in the Adult Hippocampus

Suh, H., Consiglio, A., Ray, J., Sawai, T., D’Amour, K. A., & Gage, F. H. (2007) · Cell stem cell · doi:10.1016/j.stem.2007.09.002 · Cited by 818 · see citing works

New Neurons Follow the Flow of Cerebrospinal Fluid in the Adult Brain

Sawamoto, K., Wichterle, H., González-Pérez, Ó., Cholfin, J. A., Yamada, M., Spassky, N., Murcia, N. S., García‐Verdugo, J. M., Marín, Ó., Rubenstein, J. L. R., et al. (2006) · Science · doi:10.1126/science.1119133 · Cited by 803 · see citing works

Brain inflammation and adult neurogenesis: The dual role of microglia

Ekdahl, C. T., Kokaia, Z., & Lindvall, O. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2008.06.052 · Cited by 801 · see citing works

Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment

Warner‐Schmidt, J. L., & Duman, R. S. (2006) · Hippocampus · doi:10.1002/hipo.20156 · Cited by 787 · see citing works

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

Mao, Y., Ge, X., Frank, C. L., Madison, J. M., Koehler, A. N., Doud, M. K., Tassa, C., Berry-Scott, E., Soda, T., Singh, K. K., et al. (2009) · Cell · doi:10.1016/j.cell.2008.12.044 · Cited by 768 · see citing works

GABAergic Excitation Promotes Neuronal Differentiation in Adult Hippocampal Progenitor Cells

Tozuka, Y., Fukuda, S., Namba, T., Seki, T., & Hisatsune, T. (2005) · Neuron · doi:10.1016/j.neuron.2005.08.023 · Cited by 741 · see citing works

Neurons born in the adult dentate gyrus form functional synapses with target cells

Toni, N., Laplagne, D. A., Zhao, C., Lombardi, G., Ribak, C. E., Gage, F. H., & Schinder, A. F. (2008) · Nature Neuroscience · doi:10.1038/nn.2156 · Cited by 741 · see citing works

Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains

Imayoshi, I., Sakamoto, M., Yamaguchi, M., Mori, K., & Kageyama, R. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4987-09.2010 · Cited by 716 · see citing works

Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging

Lugert, S., Basak, O., Knuckles, P., Haussler, U., Fabel, K., Götz, M., Haas, C. A., Kempermann, G., Taylor, V., & Giachino, C. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.03.017 · Cited by 704 · see citing works

Stress and adult neurogenesis

Mirescu, C., & Gould, E. (2006) · Hippocampus · doi:10.1002/hipo.20155 · Cited by 701 · see citing works

In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog

Ahn, S., & Joyner, A. L. (2005) · Nature · doi:10.1038/nature03994 · Cited by 699 · see citing works

FGF-2-Responsive Neuronal Progenitors Reside in Proliferative and Quiescent Regions of the Adult Rodent Brain

Palmer, T. D., Ray, J., & Gage, F. H. (1995) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1995.1035 · Cited by 699 · see citing works

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

Zhang, F., Gradinaru, V., Adamantidis, A. R., Durand, R., Airan, R. D., de Lecea, L., & Deisseroth, K. (2010) · Nature Protocols · doi:10.1038/nprot.2009.226 · Cited by 692 · see citing works

Neuronal differentiation in the adult hippocampus recapitulates embryonic development

Espósito, M. S., Piatti, V. C., Laplagne, D. A., Morgenstern, N. A., Ferrari, C. C., Pitossi, F. J., & Schinder, A. F. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3114-05.2005 · Cited by 679 · see citing works

Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation

Aimone, J. B., Deng, W., & Gage, F. H. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.010 · Cited by 663 · see citing works

How widespread is adult neurogenesis in mammals?

Gould, E. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2147 · Cited by 658 · see citing works

Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years

Knoth, R., Singec, I., Ditter, M., Pantazis, G., Capetian, P., Meyer, R. P., Horvat, V., Volk, B., & Kempermann, G. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008809 · Cited by 650 · see citing works

Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

Kuwabara, T., Hsieh, J., Muotri, A., Yeo, G., Warashina, M., Lie, D. C., Moore, L., Nakashima, K., Asashima, M., & Gage, F. H. (2009) · Nature Neuroscience · doi:10.1038/nn.2360 · Cited by 648 · see citing works

Neuronal fate determinants of adult olfactory bulb neurogenesis

Hack, M., Saghatelyan, A., de Chevigny, A., Pfeifer, A., Ashery-Padan, R., Lledo, P., & Götz, M. (2005) · Nature Neuroscience · doi:10.1038/nn1479 · Cited by 648 · see citing works

Origin of New Glial Cells in Intact and Injured Adult Spinal Cord

Barnabé-Heider, F., Göritz, C., Sabelström, H., Takebayashi, H., Pfrieger, F. W., Meletis, K., & Frisén, J. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.07.014 · Cited by 628 · see citing works

Retrospective Birth Dating of Cells in Humans

Spalding, K. L., Bhardwaj, R. D., Buchholz, B. A., Druid, H., & Frisén, J. (2005) · Cell · doi:10.1016/j.cell.2005.04.028 · Cited by 626 · see citing works

NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus

Tashiro, A., Sandler, V. M., Toni, N., Zhao, C., & Gage, F. H. (2006) · Nature · doi:10.1038/nature05028 · Cited by 620 · see citing works

Effects of Adult Neurogenesis on Synaptic Plasticity in the Rat Dentate Gyrus

Snyder, J. S., Kee, N., & Wojtowicz, J. M. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.6.2423 · Cited by 619 · see citing works

Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

Stranahan, A. M., Arumugam, T. V., Cutler, R. G., Lee, K. M., Egan, J. M., & Mattson, M. P. (2008) · Nature Neuroscience · doi:10.1038/nn2055 · Cited by 610 · see citing works

Mosaic Analysis with Double Markers in Mice

Zong, H., Espinosa, J. S., Su, H. H., Muzumdar, M. D., & Luo, L. (2005) · Cell · doi:10.1016/j.cell.2005.02.012 · Cited by 586 · see citing works

FoxO3 Regulates Neural Stem Cell Homeostasis

Renault, V. M., Rafalski, V. A., Morgan, A. A., Salih, D. A. M., Brett, J. O., Webb, A. E., Villeda, S. A., Thekkat, P. U., Guillerey, C., Denko, N. C., et al. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2009.09.014 · Cited by 586 · see citing works

Synapse formation on neurons born in the adult hippocampus

Toni, N., Teng, E. M., Bushong, E. A., Aimone, J. B., Zhao, C., Consiglio, A., van Praag, H., Martone, M. E., Ellisman, M. H., & Gage, F. H. (2007) · Nature Neuroscience · doi:10.1038/nn1908 · Cited by 579 · see citing works

In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus

Roy, N. S., Wang, S., Jiang, L., Kang, J., Benraiss, A., Harrison‐Restelli, C., Fraser, R. A. R., Couldwell, W. T., Kawaguchi, A., Okano, H., et al. (2000) · Nature Medicine · doi:10.1038/73119 · Cited by 559 · see citing works

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

Han, Y.-G., Spassky, N., Romaguera-Ros, M., Garcia-Verdugo, J.-M., Aguilar, A., Schneider-Maunoury, S., & Alvarez-Buylla, A. (2008) · Nature Neuroscience · doi:10.1038/nn2059 · Cited by 547 · see citing works

De novo generation of neuronal cells from the adult mouse brain.

Richards, L. J., Kilpatrick, T. J., & Bartlett, P. F. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.18.8591 · Cited by 544 · see citing works

Disrupted-In-Schizophrenia 1 Regulates Integration of Newly Generated Neurons in the Adult Brain

Duan, X., Chang, J. H., Ge, S., Faulkner, R. L., Kim, J. Y., Kitabatake, Y., Liu, X.-B., Yang, C.-H., Jordan, J. D., Ma, D. K., et al. (2007) · Cell · doi:10.1016/j.cell.2007.07.010 · Cited by 538 · see citing works

Multipotent Stem/Progenitor Cells with Similar Properties Arise from Two Neurogenic Regions of Adult Human Brain

Kukekov, V. G., Laywell, E. D., Suslov, O. N., Davies, K. G., Scheffler, B., Thomas, L. B., O'Brien, T. J., Kusakabe, M., & Steindler, D. A. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7028 · Cited by 522 · see citing works

Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh

Favaro, R., Valotta, M., Ferri, L., Latorre, E., Mariani, J., Giachino, C., Lancini, C., Tosetti, V., Ottolenghi, S., Taylor, V., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2397 · Cited by 504 · see citing works

Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain

Manganas, L. N., Zhang, X., Li, Y., Hazel, R. D., Smith, S. D. B., Wagshul, M. E., Henn, F. A., Benveniste, H., Djurić, P. M., Enikolopov, G., et al. (2007) · Science · doi:10.1126/science.1147851 · Cited by 486 · see citing works

Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus

Mira, H., Andreu, Z., Suh, H., Lie, D. C., Jessberger, S., Consiglio, A., San Emeterio, J., Hortigüela, R., Marqués-Torrejón, M. Á., Nakashima, K., et al. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.04.016 · Cited by 480 · see citing works

Neurod1 is essential for the survival and maturation of adult-born neurons

Gao, Z., Ure, K., Ables, J. L., Lagace, D. C., Nave, K.-A., Goebbels, S., Eisch, A. J., & Hsieh, J. (2009) · Nature Neuroscience · doi:10.1038/nn.2385 · Cited by 473 · see citing works

Deficient Neurogenesis in Forebrain-Specific Presenilin-1 Knockout Mice Is Associated with Reduced Clearance of Hippocampal Memory Traces

Feng, R., Rampon, C., Tang, Y., Shrom, D., Jin, J., Kyin, M., Sopher, B. L., Martin, G. M., Kim, S., Langdon, R. B., et al. (2001) · Neuron · doi:10.1016/s0896-6273(01)00523-2 · Cited by 467 · see citing works

Neurons Generated in the Adult Brain Are Recruited into Functional Circuits

Paton, J. A., & Nottebohm, F. (1984) · Science · doi:10.1126/science.6474166 · Cited by 466 · see citing works

Contribution of olfactory neural stem cells to tissue maintenance and regeneration

Leung, C. T., Coulombe, P. A., & Reed, R. R. (2007) · Nature Neuroscience · doi:10.1038/nn1882 · Cited by 466 · see citing works

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

Paik, J.-H., Ding, Z., Narurkar, R., Ramkissoon, S., Muller, F., Kamoun, W. S., Chae, S.-S., Zheng, H., Ying, H., Mahoney, J., et al. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2009.09.013 · Cited by 459 · see citing works

Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke

Carlén, M., Meletis, K., Göritz, C., Darsalia, V., Evergren, E., Tanigaki, K., Amendola, M., Barnabé‐Heider, F., Yeung, M. S. Y., Naldini, L., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2268 · Cited by 453 · see citing works

The Adult Substantia Nigra Contains Progenitor Cells with Neurogenic Potential

Lie, D. C., Dziewczapolski, G., Willhoite, A. R., Kaspar, B. K., Shults, C. W., & Gage, F. H. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06639.2002 · Cited by 449 · see citing works

Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors

Liu, X., Wang, Q., Haydar, T. F., & Bordey, A. (2005) · Nature Neuroscience · doi:10.1038/nn1522 · Cited by 446 · see citing works

Neurodegenerative disease and adult neurogenesis

Winner, B., Kohl, Z., & Gage, F. H. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07613.x · Cited by 405 · see citing works

Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells

Lim, D., Huang, Y.-C., Swigut, T., Mirick, A. L., García-Verdugo, J., Wysocka, J., Ernst, P., & Álvarez-Buylla, A. (2009) · Nature · doi:10.1038/nature07726 · Cited by 400 · see citing works

Excitatory GABA Action Is Essential for Morphological Maturation of Cortical Neurons <i>In Vivo</i>

Cancedda, L., Fiumelli, H., Chen, K., & Poo, M.-M. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5169-06.2007 · Cited by 392 · see citing works

Endothelial Trophic Support of Neuronal Production and Recruitment from the Adult Mammalian Subependyma

Leventhal, C., Rafii, S., Rafii, D., Shahar, A., & Goldman, S. A. (1999) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1999.0762 · Cited by 389 · see citing works

Adult generation of glutamatergic olfactory bulb interneurons

Brill, M. S., Ninkovic, J., Winpenny, E. M., Hodge, R. D., Ozen, I., Yang, R., Lepier, A., Gascón, S., Erdélyi, F., Szabó, G., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2416 · Cited by 364 · see citing works

Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis

Lim, D. A., & Álvarez-Buylla, A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.13.7526 · Cited by 362 · see citing works

Notch in the Vertebrate Nervous System: An Old Dog with New Tricks

Pierfelice, T. J., Alberi, L. A., & Gaiano, N. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.031 · Cited by 353 · see citing works

Epigenetic Modulation of Seizure-Induced Neurogenesis and Cognitive Decline

Jessberger, S., Nakashima, K., Clemenson, G. D., Mejia, E., Mathews, E. A., Ure, K., Ogawa, S., Sinton, C. M., Gage, F. H., & Hsieh, J. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0110-07.2007 · Cited by 353 · see citing works

In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells

Beckervordersandforth, R., Tripathi, P., Ninkovic, J., Bayam, E., Lepier, A., Stempfhuber, B., Kirchhoff, F., Hirrlinger, J., Haslinger, A., Lie, D. C., et al. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.11.017 · Cited by 335 · see citing works

Integration of New Neurons into Functional Neural Networks

Ramı́rez-Amaya, V., Marrone, D. F., Gage, F. H., Worley, P. F., & Barnes, C. A. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2195-06.2006 · Cited by 332 · see citing works

Epigenetic choreographers of neurogenesis in the adult mammalian brain

Dengke, K., Marchetto, M. C., Guo, J. U., Ming, G., Gage, F. H., & Song, H. (2010) · Nature Neuroscience · doi:10.1038/nn.2672 · Cited by 332 · see citing works

CD133 + neural stem cells in the ependyma of mammalian postnatal forebrain

Coskun, V., Wu, H., Blanchi, B., Tsao, S. W., Kim, K., Zhao, J., Biancotti, J. C., Hutnick, L. K., Krueger, R. C., Fan, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710000105 · Cited by 331 · see citing works

GABA-cAMP Response Element-Binding Protein Signaling Regulates Maturation and Survival of Newly Generated Neurons in the Adult Hippocampus

Jagasia, R., Steib, K., Englberger, E., Herold, S., Faus-Keßler, T., Saxe, M., Gage, F. H., Song, H., & Lie, D. C. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1054-09.2009 · Cited by 328 · see citing works

Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro.

Gabay, L., Lowell, S., Lee, R.-B. L., & Anderson, D. J. (2003) · Neuron · doi:10.1016/s0896-6273(03)00637-8 · Cited by 326 · see citing works

DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212

Kim, J. Y., Duan, X., Liu, C. Y., Jang, M.-H., Guo, J. U., Pow-anpongkul, N., Kang, E., Song, H., & Ming, G.-L. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.008 · Cited by 319 · see citing works

RBPJκ-Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus

Ehm, O., Göritz, C., Covic, M., Schäffner, I., Schwarz, T. J., Karaca, E., Kempkes, B., Kremmer, E., Pfrieger, F. W., Espinosa, L., et al. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1567-10.2010 · Cited by 315 · see citing works

Identification and characterization of neuroblasts in the subventricular zone and rostral migratory stream of the adult human brain

Wang, C., Liu, F., Liu, Y.-Y., Zhao, C.-H., You, Y., Wang, L., Zhang, J., Wei, B. K., Ma, T., Zhang, Q., et al. (2011) · Cell Research · doi:10.1038/cr.2011.83 · Cited by 309 · see citing works

Subventricular Zone-Derived Neural Progenitor Cells Migrate Along a Blood Vessel Scaffold Toward The Post-stroke Striatum

Kojima, T., Hirota, Y., Ema, M., Takahashi, S., Miyoshi, I., Okano, H., & Sawamoto, K. (2010) · Stem Cells · doi:10.1002/stem.306 · Cited by 307 · see citing works

Epigenetic Regulation of miR-184 by MBD1 Governs Neural Stem Cell Proliferation and Differentiation

Liu, C., Teng, Z., Santistevan, N. J., Szulwach, K. E., Guo, W., Jin, P., & Zhao, X. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.02.017 · Cited by 304 · see citing works

Identification of Astrocyte-expressed Factors That Modulate Neural Stem/Progenitor Cell Differentiation

Barkho, B. Z., Song, H., Aimone, J. B., Smrt, R. D., Kuwabara, T., Nakashima, K., Gage, F. H., & Zhao, X. (2006) · Stem Cells and Development · doi:10.1089/scd.2006.15.407 · Cited by 303 · see citing works

Development of neural stem cell in the adult brain

Duan, X., Kang, E., Liu, C. Y., Ming, G., & Song, H. (2008) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2008.04.001 · Cited by 302 · see citing works

Orphan nuclear receptor TLX activates Wnt/β-catenin signalling to stimulate neural stem cell proliferation and self-renewal

Qu, Q., Sun, G., Li, W., Su, Y., Ye, P., Zhao, C., Yu, R. T., Gage, F. H., Evans, R. M., & Shi, Y. (2009) · Nature Cell Biology · doi:10.1038/ncb2001 · Cited by 299 · see citing works

GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knockin Mice

Li, G., Bien-Ly, N., Andrews-Zwilling, Y., Xu, Q., Bernardo, A., Ring, K., Halabisky, B., Deng, C., Mahley, R. W., & Huang, Y. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2009.10.015 · Cited by 288 · see citing works

Is adult neurogenesis essential for olfaction?

Lazarini, F., & Lledo, P. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.09.006 · Cited by 285 · see citing works

Brain micro-ecologies: neural stem cell niches in the adult mammalian brain

Riquelme, P. A., Drapeau, E., & Doetsch, F. K. (2007) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2006.2016 · Cited by 277 · see citing works

High Levels of Id1 Expression Define B1 Type Adult Neural Stem Cells

Nam, H.-S., & Benezra, R. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.08.017 · Cited by 272 · see citing works

LIF and BMP signaling generate separate and discrete types of GFAP-expressing cells

Bonaguidi, M. A., McGuire, T. L., Hu, M., Kan, L., Samanta, J., & Kessler, J. A. (2005) · Development · doi:10.1242/dev.02166 · Cited by 268 · see citing works

Seizures accelerate functional integration of adult-generated granule cells

Overstreet-Wadiche, L. S., Bromberg, D. A., Bensen, A. L., & Westbrook, G. L. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.5508-05.2006 · Cited by 266 · see citing works

Directed differentiation of hippocampal stem/progenitor cells in the adult brain

Jessberger, S., Toni, N., Clemenson, G. D., Ray, J., & Gage, F. H. (2008) · Nature Neuroscience · doi:10.1038/nn.2148 · Cited by 265 · see citing works

Time-lapse imaging of disease progression in deep brain areas using fluorescence microendoscopy

Barretto, R. P. J., Ko, T. H., Jung, J. C., Wang, T. J., Capps, G., Waters, A. C., Ziv, Y., Attardo, A., Recht, L. D., & Schnitzer, M. J. (2011) · Nature Medicine · doi:10.1038/nm.2292 · Cited by 253 · see citing works

Transneuronal circuit tracing with neurotropic viruses

Callaway, E. M. (2008) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.03.007 · Cited by 252 · see citing works

Adult neurogenesis promotes synaptic plasticity in the olfactory bulb

Nissant, A., Bardy, C., Katagiri, H., Murray, K., & Lledo, P. (2009) · Nature Neuroscience · doi:10.1038/nn.2298 · Cited by 252 · see citing works

Environment Matters: Synaptic Properties of Neurons Born in the Epileptic Adult Brain Develop to Reduce Excitability

Jakubs, K., Nanobashvili, A., Bonde, S., Ekdahl, C. T., Kokaia, Z., Kokaia, M., & Lindvall, O. (2006) · Neuron · doi:10.1016/j.neuron.2006.11.004 · Cited by 250 · see citing works

Cell types to order: temporal specification of CNS stem cells

Okano, H., & Temple, S. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.04.003 · Cited by 240 · see citing works

Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons

Smrt, R. D., Eaves-Egenes, J., Barkho, B. Z., Santistevan, N. J., Zhao, C., Aimone, J. B., Gage, F. H., & Zhao, X. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.04.005 · Cited by 239 · see citing works

Prox1 Is Required for Granule Cell Maturation and Intermediate Progenitor Maintenance During Brain Neurogenesis

Lavado, A., Lagutin, O. V., Chow, L. M. L., Baker, S. J., & Oliver, G. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000460 · Cited by 238 · see citing works

Fragile X Mental Retardation Protein Regulates Proliferation and Differentiation of Adult Neural Stem/Progenitor Cells

Luo, Y., Shan, G., Guo, W., Smrt, R. D., Johnson, E. B., Li, X., Pfeiffer, R. L., Szulwach, K. E., Duan, R., Barkho, B. Z., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1000898 · Cited by 238 · see citing works

Doublecortin maintains bipolar shape and nuclear translocation during migration in the adult forebrain

Koizumi, H., Higginbotham, H., Poon, T., Tanaka, T., Brinkman, B. C., & Gleeson, J. G. (2006) · Nature Neuroscience · doi:10.1038/nn1704 · Cited by 237 · see citing works

Immune Influence on Adult Neural Stem Cell Regulation and Function

Carpentier, P. A., & Palmer, T. D. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.038 · Cited by 235 · see citing works

Reelin Regulates Neuronal Progenitor Migration in Intact and Epileptic Hippocampus

Gong, C., Wang, T., Huang, H. S., & Parent, J. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3111-06.2007 · Cited by 233 · see citing works

NMDA Receptors Activated by Subventricular Zone Astrocytic Glutamate Are Critical for Neuroblast Survival Prior to Entering a Synaptic Network

Platel, J., Dave, K. A., Gordon, V., Lacar, B., Rubio, M. E., & Bordey, A. (2010) · Neuron · doi:10.1016/j.neuron.2010.03.009 · Cited by 225 · see citing works

Anatomical gradients of adult neurogenesis and activity: Young neurons in the ventral dentate gyrus are activated by water maze training

Snyder, J. S., Radik, R., Wojtowicz, J. M., & Cameron, H. A. (2008) · Hippocampus · doi:10.1002/hipo.20525 · Cited by 224 · see citing works

Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning

Guo, W., Allan, A. M., Zong, R.-T., Zhang, L., Johnson, E. B., Schaller, E., Murthy, A. C., Goggin, S. L., Eisch, A. J., Oostra, B. A., et al. (2011) · Nature Medicine · doi:10.1038/nm.2336 · Cited by 221 · see citing works

Signaling in adult neurogenesis

Mu, Y., Lee, S. W., & Gage, F. H. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.04.010 · Cited by 217 · see citing works

Chordin-induced lineage plasticity of adult SVZ neuroblasts after demyelination

Jablonska, B., Aguirre, A. A., Raymond, M., Szabó, G., Kitabatake, Y., Sailor, K. A., Ming, G., Song, H., & Gallo, V. (2010) · Nature Neuroscience · doi:10.1038/nn.2536 · Cited by 215 · see citing works

New Neurons Clear the Path of Astrocytic Processes for Their Rapid Migration in the Adult Brain

Kaneko, N., Marín, O., Koike, M., Hirota, Y., Uchiyama, Y., Wu, J. Y., Lu, Q., Tessier-Lavigne, M., Alvarez-Buylla, A., Okano, H., et al. (2010) · Neuron · doi:10.1016/j.neuron.2010.06.018 · Cited by 212 · see citing works

A Dlx2- and Pax6-Dependent Transcriptional Code for Periglomerular Neuron Specification in the Adult Olfactory Bulb

Brill, M. S., Snapyan, M., Wohlfrom, H., Ninkovic, J., Jawerka, M., Mastick, G. S., Ashery‐Padan, R., Saghatelyan, A., Berninger, B., & Götz, M. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0700-08.2008 · Cited by 212 · see citing works

Postnatal Deletion of Numb/Numblike Reveals Repair and Remodeling Capacity in the Subventricular Neurogenic Niche

Kuo, C. T., Mirzadeh, Z., Soriano‐Navarro, M., Rašin, M. R., Wang, D., Shen, J., Šestan, N., García‐Verdugo, J. M., Álvarez-Buylla, A., Jan, L. Y., et al. (2006) · Cell · doi:10.1016/j.cell.2006.10.041 · Cited by 211 · see citing works

Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain

Faulkner, R. L., Jang, M., Liu, X.-B., Duan, X., Sailor, K. A., Kim, J. Y., Ge, S., Jones, E. G., Ming, G., Song, H., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806658105 · Cited by 208 · see citing works

The Developmental Stage of Dentate Granule Cells Dictates Their Contribution to Seizure-Induced Plasticity

Kron, M. M., Zhang, H., & Parent, J. M. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5655-09.2010 · Cited by 208 · see citing works

Synaptic integration and plasticity of new neurons in the adult hippocampus

Ge, S., Sailor, K. A., Ming, G., & Song, H. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.155655 · Cited by 206 · see citing works

Imbalance between GABAergic and glutamatergic transmission impairs adult neurogenesis in an animal model of Alzheimer’s Disease.

Sun, B., Halabisky, B., Zhou, Y., Palop, J. J., Yu, G., Mucke, L., & Gan, L. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2009.10.003 · Cited by 205 · see citing works

Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus

Lacefield, C. O., Itskov, V., Reardon, T., Hen, R., & Gordon, J. A. (2012) · Hippocampus · doi:10.1002/hipo.20860 · Cited by 188 · see citing works

Tracking adult stem cells

Snippert, H. J. G., & Clevers, H. C. (2011) · EMBO Reports · doi:10.1038/embor.2010.216 · Cited by 180 · see citing works

Learning and survival of newly generated neurons: when time matters

Mouret, A., Gheusi, G., Gabellec, M.-M., de Chaumont, F., Olivo-Marin, J.-C., & Lledo, P.-M. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.2954-08.2008 · Cited by 180 · see citing works

Delayed Development of Adult-Generated Granule Cells in Dentate Gyrus

Overstreet‐Wadiche, L., Bensen, A. L., & Westbrook, G. L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4111-05.2006 · Cited by 179 · see citing works

Hedgehog Signaling in the Subventricular Zone Is Required for Both the Maintenance of Stem Cells and the Migration of Newborn Neurons

Balordi, F., & Fishell, G. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1040-07.2007 · Cited by 173 · see citing works

Non-Cell-Autonomous Effects of Presenilin 1 Variants on Enrichment-Mediated Hippocampal Progenitor Cell Proliferation and Differentiation

Choi, S. H., Veeraraghavalu, K., Lazarov, O., Marler, S., Ransohoff, R. M., Ramirez, J., & Sisodia, S. S. (2008) · Neuron · doi:10.1016/j.neuron.2008.07.033 · Cited by 171 · see citing works

Spatial and temporal expression of short, long/medium, or both opsins in human fetal cones

Xiao, M., & Hendrickson, A. E. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20001002)425:4 · Cited by 165 · see citing works

Ephrins and Eph receptors in stem cells and cancer

Genander, M., & Frisén, J. (2010) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2010.08.005 · Cited by 152 · see citing works

The Chemokine Stromal Cell-Derived Factor-1 Regulates GABAergic Inputs to Neural Progenitors in the Postnatal Dentate Gyrus

Bhattacharyya, B. J., Banisadr, G., Jung, H., Ren, D., Cronshaw, D. G., Zou, Y.-R., & Miller, R. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1677-08.2008 · Cited by 149 · see citing works

Krüppel-Like Factor 9 Is Necessary for Late-Phase Neuronal Maturation in the Developing Dentate Gyrus and during Adult Hippocampal Neurogenesis

Scobie, K. N., Hall, B. J., Wilke, S. A., Klemenhagen, K. C., Fujii‐Kuriyama, Y., Ghosh, A., Hen, R., & Sahay, A. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2260-09.2009 · Cited by 144 · see citing works

Everything that glitters isn't gold: a critical review of postnatal neural precursor analyses.

Breunig, J., Arellano, J., Macklis, J., & Rakic, P. (2007) · Cell Stem Cell · doi:10.1016/j.stem.2007.11.008 · Cited by 136 · see citing works

Signaling in adult neurogenesis: from stem cell niche to neuronal networks

Ninkovic, J., & Götz, M. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.04.006 · Cited by 136 · see citing works

Adult neurogenesis and the plasticity of the dentate gyrus network

Mongiat, L. A., & Schinder, A. F. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07603.x · Cited by 127 · see citing works

Learning-Induced Survival of New Neurons Depends on the Cognitive Status of Aged Rats

Drapeau, E., Montaron, M., Aguerre, S., & Abrous, D. N. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1031-07.2007 · Cited by 119 · see citing works

A Novel Secretory Factor, Neurogenesin-1, Provides Neurogenic Environmental Cues for Neural Stem Cells in the Adult Hippocampus

Ueki, T., Tanaka, M., Yamashita, K., Mikawa, S., Qiu, Z., Maragakis, N. J., Hevner, R. F., Miura, N., Sugimura, H., & Sato, K. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-37-11732.2003 · Cited by 115 · see citing works

Disruption of Adult Neurogenesis in the Olfactory Bulb Affects Social Interaction but not Maternal Behavior

Feierstein, C. E., Lazarini, F., Wagner, S., Gabellec, M., de Chaumont, F., Olivo‐Marín, J., Boussin, F. D., Lledo, P., & Gheusi, G. (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00176 · Cited by 112 · see citing works

The specific role of histone deacetylase 2 in adult neurogenesis

Jawerka, M., Colak, D., Dimou, L., Spiller, C., Lagger, S., Montgomery, R. L., Olson, E. N., Wurst, W., Göttlicher, M., & Götz, M. (2010) · Neuron Glia Biology · doi:10.1017/s1740925x10000049 · Cited by 107 · see citing works

Epigenetic regulation of neurogenesis in the adult mammalian brain

Sun, J., Sun, J., Ming, G., & Song, H. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07607.x · Cited by 102 · see citing works

EphB Signaling Controls Lineage Plasticity of Adult Neural Stem Cell Niche Cells

Nomura, T., Göritz, C., Catchpole, T., Henkemeyer, M. J., & Frisén, J. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.11.009 · Cited by 96 · see citing works

Fragile X mental retardation protein regulates new neuron differentiation in the adult olfactory bulb

Scotto-Lomassese, S., Nissant, A., Mota, T., Néant-Féry, M., Oostra, B. A., Greer, C. A., Lledo, P.-M., Trembleau, A., & Caillé, I. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.5514-10.2011 · Cited by 80 · see citing works

Modeling new neuron function: a history of using computational neuroscience to study adult neurogenesis

Aimone, J. B., & Gage, F. H. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07615.x · Cited by 77 · see citing works

Dopaminergic Modulation of Cortical Inputs during Maturation of Adult-Born Dentate Granule Cells

Mu, Y., Zhao, C., & Gage, F. H. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4913-10.2011 · Cited by 75 · see citing works

Visualization and genetic manipulation of adult neurogenesis using transgenic mice

Dhaliwal, J., & Lagace, D. C. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07600.x · Cited by 70 · see citing works

How, When, and Where New Inhibitory Neurons Release Neurotransmitters in the Adult Olfactory Bulb

Bardy, C., Alonso, M., Bouthour, W., & Lledo, P. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4543-10.2010 · Cited by 64 · see citing works

Presenilin 1 Mutants Impair the Self-Renewal and Differentiation of Adult Murine Subventricular Zone-Neuronal Progenitors via Cell-Autonomous Mechanisms Involving Notch Signaling

Veeraraghavalu, K., Choi, S. H., Zhang, X., & Sisodia, S. S. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0527-10.2010 · Cited by 61 · see citing works

A Critical Time Window for the Recruitment of Bulbar Newborn Neurons by Olfactory Discrimination Learning

Belnoue, L., Grosjean, N., Abrous, D. N., & Koehl, M. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3941-10.2011 · Cited by 49 · see citing works

Adult neurogenesis as a cellular model to study schizophrenia

Christian, K. M., Song, H., & Ming, G. (2010) · Cell Cycle · doi:10.4161/cc.9.4.10932 · Cited by 21 · see citing works

New directions in neuroregeneration

Kim, J. Y., Schafer, J., & Ming, G. (2006) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.6.8.735 · Cited by 16 · see citing works

Continual lifelong learning with neural networks: A review

Parisi, G. I., Kemker, R., Part, J. L., Kanan, C., & Wermter, S. (2019) · Neural Networks · doi:10.1016/j.neunet.2019.01.012 · Cited by 3,117 · see citing works

Molecular diversity and specializations among the cells of the adult mouse brain

Saunders, A., Macosko, E. Z., Wysoker, A., Goldman, M., Krienen, F. M., de Rivera, H., Bien, E., Baum, M., Bortolin, L., Wang, S., et al. (2018) · Cell · doi:10.1016/j.cell.2018.07.028 · Cited by 1,847 · see citing works

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

Bussian, T. J., Aziz, A., Meyer, C. F., Swenson, B. L., van Deursen, J. M., & Baker, D. J. (2018) · Nature · doi:10.1038/s41586-018-0543-y · Cited by 1,289 · see citing works

Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States

Mattson, M. P., & Arumugam, T. V. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.05.011 · Cited by 1,242 · see citing works

Single-cell sequencing-based technologies will revolutionize whole-organism science

Shapiro, E., Biezuner, T., & Linnarsson, S. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3542 · Cited by 1,177 · see citing works

The Role of Microglia in the Healthy Brain: Figure 1.

Tremblay, M.-È., Stevens, B., Sierra, A., Wake, H., Bessis, A., & Nimmerjahn, A. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4158-11.2011 · Cited by 992 · see citing works

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

Liu, L., Zhang, K., Sandoval, H., Yamamoto, S., Jaiswal, M., Sanz, E., Li, Z., Hui, J., Graham, B. H., Quintana, A., et al. (2015) · Cell · doi:10.1016/j.cell.2014.12.019 · Cited by 876 · see citing works

In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics

Bonaguidi, M. A., Wheeler, M. A., Shapiro, J. S., Stadel, R. P., Sun, G. J., Ming, G.-L., & Song, H. (2011) · Cell · doi:10.1016/j.cell.2011.05.024 · Cited by 831 · see citing works

Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis

Shin, J., Berg, D. A., Zhu, Y., Shin, J. Y., Song, J., Bonaguidi, M. A., Enikolopov, G., Nauen, D. W., Christian, K. M., Ming, G.-L., et al. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2015.07.013 · Cited by 784 · see citing works

Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury

Llorens-Bobadilla, E., Zhao, S., Baser, A., Saiz-Castro, G., Zwadlo, K., & Martin-Villalba, A. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2015.07.002 · Cited by 778 · see citing works

Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later

Bond, A. M., Ming, G.-L., & Song, H. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2015.09.003 · Cited by 791 · see citing works

The role of adult hippocampal neurogenesis in brain health and disease

Toda, T., Parylak, S. L., Linker, S. B., & Gage, F. H. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0036-2 · Cited by 719 · see citing works

The organization of the stress system and its dysregulation in depressive illness

Gold, P. W. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.163 · Cited by 654 · see citing works

Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons

Habib, N., Li, Y., Heidenreich, M., Swiech, L., Avraham-Davidi, I., Trombetta, J. J., Hession, C., Zhang, F., & Regev, A. (2016) · Science · doi:10.1126/science.aad7038 · Cited by 601 · see citing works

Neural stem cells: origin, heterogeneity and regulation in the adult mammalian brain

Obernier, K., & Alvarez-Buylla, A. (2019) · Development · doi:10.1242/dev.156059 · Cited by 578 · see citing works

Pattern separation: a common function for new neurons in hippocampus and olfactory bulb

Sahay, A., Wilson, D. A., & Hen, R. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.012 · Cited by 514 · see citing works

Depression and Hippocampal Neurogenesis: A Road to Remission?

Eisch, A. J., & Petrik, D. (2012) · Science · doi:10.1126/science.1222941 · Cited by 516 · see citing works

Neural Mechanisms of Stress Resilience and Vulnerability

Franklin, T. B., Saab, B. J., & Mansuy, I. M. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.016 · Cited by 500 · see citing works

Neurogenesis in the embryonic and adult brain: same regulators, different roles

Urbán, N., & Guillemot, F. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00396 · Cited by 493 · see citing works

Embryonic origin of postnatal neural stem cells

Fuentealba, L. C., Rompani, S. B., Parraguez, J. I., Obernier, K., Romero, R., Cepko, C. L., & Alvarez-Buylla, A. (2015) · Cell · doi:10.1016/j.cell.2015.05.041 · Cited by 488 · see citing works

Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1

Yousef, H., Czupalla, C. J., Lee, D., Chen, M. B., Burke, A. N., Zera, K. A., Zandstra, J., Berber, E., Lehallier, B., Mathur, V., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0440-4 · Cited by 442 · see citing works

Ageing, Cellular Senescence and Neurodegenerative Disease

Kritsilis, M., V. Rizou, S., Koutsoudaki, P. N., Evangelou, K., Gorgoulis, V. G., & Papadopoulos, D. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19102937 · Cited by 448 · see citing works

NADPH oxidase in brain injury and neurodegenerative disorders

Ma, M. W., Wang, J., Zhang, Q., Wang, R., Dhandapani, K. M., Vadlamudi, R. K., & Brann, D. W. (2017) · Molecular Neurodegeneration · doi:10.1186/s13024-017-0150-7 · Cited by 432 · see citing works

Psychoneuroimmunology of early-life stress: the hidden wounds of childhood trauma?

Danese, A., & J Lewis, S. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.198 · Cited by 393 · see citing works

Microglial Dynamics and Role in the Healthy and Diseased Brain: A Paradigm of Functional Plasticity

Gomez-Nicola, D., & Perry, V. H. (2015) · The Neuroscientist · doi:10.1177/1073858414530512 · Cited by 340 · see citing works

Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells

Furutachi, S., Miya, H., Watanabe, T., Kawai, H., Yamasaki, N., Harada, Y., Imayoshi, I., Nelson, M., Nakayama, K. I., Hirabayashi, Y., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.3989 · Cited by 329 · see citing works

Wnt signaling in the nervous system and in Alzheimer's disease

Inestrosa, N. C., & Varela-Nallar, L. (2014) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjt051 · Cited by 324 · see citing works

Neurobiology of Resilience: Interface Between Mind and Body

Cathomas, F., Murrough, J. W., Nestler, E. J., Han, M.-H., & Russo, S. J. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.04.011 · Cited by 296 · see citing works

Sleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive function

Kreutzmann, J. C., Havekes, R., Abel, T., & Meerlo, P. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.04.053 · Cited by 309 · see citing works

Brain development and aging: Overlapping and unique patterns of change

Tamnes, C. K., Walhovd, K. B., Dale, A. M., Østby, Y., Grydeland, H., Richardson, G., Westlye, L. T., Roddey, J. C., Hagler, D. J., Due-Tønnessen, P., et al. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2012.11.039 · Cited by 287 · see citing works

Neuronal plasticity and neurotrophic factors in drug responses

Castrén, E., & Antila, H. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.61 · Cited by 284 · see citing works

BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission

Waterhouse, E. G., An, J. J., Orefice, L. L., Baydyuk, M., Liao, G.-Y., Zheng, K., Lu, B., & Xu, B. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.0709-12.2012 · Cited by 287 · see citing works

DNA methylation atlas of the mouse brain at single-cell resolution

Liu, H., Zhou, J., Tian, W., Luo, C., Bartlett, A., Aldridge, A., Lucero, J., Osteen, J. K., Nery, J. R., Chen, H., et al. (2021) · Nature · doi:10.1038/s41586-020-03182-8 · Cited by 289 · see citing works

Evolution of oxytocin pathways in the brain of vertebrates

Knobloch, H. S., & Grinevich, V. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00031 · Cited by 259 · see citing works

The impact of sugar consumption on stress driven, emotional and addictive behaviors

Jacques, A., Chaaya, N., Beecher, K., Ali, S. A., Belmer, A., & Bartlett, S. (2019) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.05.021 · Cited by 271 · see citing works

A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis

Berg, D. A., Su, Y., Jimenez-Cyrus, D., Patel, A., Huang, N., Morizet, D., Lee, S., Shah, R., Ringeling, F. R., Jain, R., et al. (2019) · Cell · doi:10.1016/j.cell.2019.02.010 · Cited by 267 · see citing works

Adult neurogenesis in Humans

Bergmann, O., Spalding, K. L., & Frisén, J. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018994 · Cited by 256 · see citing works

Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons

Griesi-Oliveira, K., Acab, A., Gupta, A. R., Sunaga, D. Y., Chailangkarn, T., Nicol, X., Nunez, Y., Walker, M. F., Murdoch, J. D., Sanders, S. J., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.141 · Cited by 236 · see citing works

Neuronal plasticity and antidepressant actions

Castrén, E., & Hen, R. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2012.12.010 · Cited by 243 · see citing works

Adult Neurogenesis Is Sustained by Symmetric Self-Renewal and Differentiation

Obernier, K., Cebrian-Silla, A., Thomson, M., Parraguez, J. I., Anderson, R., Guinto, C., Rodas Rodriguez, J., Garcia-Verdugo, J.-M., & Alvarez-Buylla, A. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.01.003 · Cited by 250 · see citing works

Aging and Rejuvenation of Neural Stem Cells and Their Niches

Navarro Negredo, P., Yeo, R. W., & Brunet, A. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2020.07.002 · Cited by 246 · see citing works

The neurogenesis hypothesis of affective and anxiety disorders: Are we mistaking the scaffolding for the building?

Petrik, D., Lagace, D. C., & Eisch, A. J. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.09.003 · Cited by 241 · see citing works

Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia

Gaikwad, S., Puangmalai, N., Bittar, A., Montalbano, M., Garcia, S., McAllen, S., Bhatt, N., Sonawane, M., Sengupta, U., & Kayed, R. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109419 · Cited by 234 · see citing works

Maintaining genome stability in the nervous system

McKinnon, P. J. (2013) · Nature Neuroscience · doi:10.1038/nn.3537 · Cited by 229 · see citing works

Regenerative Stem Cell Therapy for Neurodegenerative Diseases: An Overview

Sivandzade, F., & Cucullo, L. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22042153 · Cited by 224 · see citing works

Parvalbumin interneurons mediate neuronal circuitry-neurogenesis coupling in the adult hippocampus

Song, J., Sun, J., Moss, J., Wen, Z., Sun, G. J., Hsu, D., Zhong, C., Davoudi, H., Christian, K. M., Toni, N., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3572 · Cited by 223 · see citing works

Somatic APP gene recombination in Alzheimer’s disease and normal neurons

Lee, M.-H., Siddoway, B., Kaeser, G. E., Segota, I., Rivera, R., Romanow, W. J., Liu, C. S., Park, C., Kennedy, G., Long, T., et al. (2018) · Nature · doi:10.1038/s41586-018-0718-6 · Cited by 210 · see citing works

Role of adult hippocampal neurogenesis in stress resilience

Levone, B. R., Cryan, J. F., & O'Leary, O. F. (2015) · Neurobiology of Stress · doi:10.1016/j.ynstr.2014.11.003 · Cited by 218 · see citing works

Aligned neurite outgrowth and directed cell migration in self-assembled monodomain gels

Berns, E. J., Sur, S., Pan, L., Goldberger, J. E., Suresh, S., Zhang, S., Kessler, J. A., & Stupp, S. I. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2013.09.077 · Cited by 208 · see citing works

Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives

Deidda, G., Bozarth, I. F., & Cancedda, L. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00119 · Cited by 192 · see citing works

Effects of Microglia on Neurogenesis

Sato, K. (2015) · Glia · doi:10.1002/glia.22858 · Cited by 187 · see citing works

Adult neurogenesis modifies excitability of the dentate gyrus

Ikrar, T., Guo, N., He, K., Besnard, A., Levinson, S., Hill, A., Lee, H.-K., Hen, R., Xu, X., & Sahay, A. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00204 · Cited by 192 · see citing works

Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis

Zywitza, V., Misios, A., Bunatyan, L., Willnow, T. E., & Rajewsky, N. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.11.003 · Cited by 183 · see citing works

Single-Cell RNA-Seq of Mouse Olfactory Bulb Reveals Cellular Heterogeneity and Activity-Dependent Molecular Census of Adult-Born Neurons

Tepe, B., Hill, M. C., Pekarek, B. T., Hunt, P. J., Martin, T. J., Martin, J. F., & Arenkiel, B. R. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.11.034 · Cited by 183 · see citing works

An atlas of gene regulatory elements in adult mouse cerebrum

Li, Y. E., Preissl, S., Hou, X., Zhang, Z., Zhang, K., Qiu, Y., Poirion, O. B., Li, B., Chiou, J., Liu, H., et al. (2021) · Nature · doi:10.1038/s41586-021-03604-1 · Cited by 185 · see citing works

Fluid Biomarkers for Synaptic Dysfunction and Loss

Camporesi, E., Nilsson, J., Brinkmalm, A., Becker, B., Ashton, N. J., Blennow, K., & Zetterberg, H. (2020) · Biomarker Insights · doi:10.1177/1177271920950319 · Cited by 165 · see citing works

FIP200 is required for maintenance and differentiation of postnatal neural stem cells

Wang, C., Liang, C.-C., Bian, Z. C., Zhu, Y., & Guan, J.-L. (2013) · Nature Neuroscience · doi:10.1038/nn.3365 · Cited by 169 · see citing works

Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons

Drew, L. J., Kheirbek, M. A., Luna, V. M., Denny, C. A., Cloidt, M. A., Wu, M. V., Jain, S., Scharfman, H. E., & Hen, R. (2016) · Hippocampus · doi:10.1002/hipo.22557 · Cited by 169 · see citing works

MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease

Saraiva, C., Paiva, J., Santos, T., Ferreira, L., & Bernardino, L. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.06.005 · Cited by 169 · see citing works

Salvianolic acid B promotes microglial M2-polarization and rescues neurogenesis in stress-exposed mice

Zhang, J., Xie, X., Tang, M., Zhang, J., Zhang, B., Zhao, Q., Han, Y., Yan, W., Peng, C., & You, Z. (2017) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2017.07.012 · Cited by 150 · see citing works

Reduced Adult Hippocampal Neurogenesis and Working Memory Deficits in the<i>Dgcr8</i>-Deficient Mouse Model of 22q11.2 Deletion-Associated Schizophrenia Can Be Rescued by IGF2

Ouchi, Y., Banno, Y., Shimizu, Y., Ando, S., Hasegawa, H., Adachi, K., & Iwamoto, T. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.2700-12.2013 · Cited by 155 · see citing works

Long-range GABAergic inputs regulate neural stem cell quiescence and control adult hippocampal neurogenesis

Bao, H., Asrican, B., Li, W., Gu, B., Wen, Z., Lim, S.-A., Haniff, I., Ramakrishnan, C., Deisseroth, K., Philpot, B., et al. (2017) · Cell stem cell · doi:10.1016/j.stem.2017.10.003 · Cited by 151 · see citing works

TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus

Matsuda, T., Murao, N., Katano, Y., Juliandi, B., Kohyama, J., Akira, S., Kawai, T., & Nakashima, K. (2015) · Nature Communications · doi:10.1038/ncomms7514 · Cited by 145 · see citing works

Regulation of Adult Neurogenesis in Mammalian Brain

Niklison-Chirou, M. V., Agostini, M., Amelio, I., & Melino, G. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21144869 · Cited by 143 · see citing works

Joggin’ the Noggin: Towards a Physiological Understanding of Exercise-Induced Cognitive Benefits

Stimpson, N. J., Davison, G., & Javadi, A.-H. (2018) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.03.018 · Cited by 134 · see citing works

Continuous postnatal neurogenesis contributes to formation of the olfactory bulb neural circuits and flexible olfactory associative learning

Sakamoto, M., Ieki, N., Miyoshi, G., Mochimaru, D., Miyachi, H., Imura, T., Yamaguchi, M., Fishell, G., Mori, K., Kageyama, R., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.0674-14.2014 · Cited by 131 · see citing works

Mesenchymal stem cell therapy for ischemic stroke: A look into treatment mechanism and therapeutic potential

Li, J., Zhang, Q., Wang, W., Lin, F., Wang, S., & Zhao, J. (2021) · Journal of Neurology · doi:10.1007/s00415-020-10138-5 · Cited by 128 · see citing works

Neuronal Circuitry Mechanisms Regulating Adult Mammalian Neurogenesis

Song, J., Olsen, R. H. J., Sun, J., Ming, G.-L., & Song, H. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018937 · Cited by 125 · see citing works

New perspectives on the biology of fragile X syndrome

Wang, T., Bray, S. M., & Warren, S. T. (2012) · Current Opinion in Genetics &amp; Development · doi:10.1016/j.gde.2012.02.002 · Cited by 116 · see citing works

Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin

Ayoub, R., Ruddy, R. M., Cox, E., Oyefiade, A., Derkach, D., Laughlin, S., Ades-aron, B., Shirzadi, Z., Fieremans, E., MacIntosh, B. J., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0985-2 · Cited by 117 · see citing works

Adult neurogenesis: bridging the gap between mice and humans

Jessberger, S., & Gage, F. H. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.07.003 · Cited by 116 · see citing works

A Review of the Brain-Gut-Microbiome Axis and the Potential Role of Microbiota in Alzheimer’s Disease

Sun, M., Ma, K., Wen, J., Wang, G., Zhang, C., Li, Q., Bao, X., & Wang, H. (2020) · Journal of Alzheimer’s Disease · doi:10.3233/jad-190872 · Cited by 113 · see citing works

Abnormal neurogenesis and cortical growth in congenital heart disease

Morton, P. D., Korotcova, L., Lewis, B. K., Bhuvanendran, S., Ramachandra, S. D., Zurakowski, D., Zhang, J., Mori, S., Frank, J. A., Jonas, R. A., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aah7029 · Cited by 101 · see citing works

From the Bottom-Up: Chemotherapy and Gut-Brain Axis Dysregulation

Bajic, J. E., Johnston, I. N., Howarth, G. S., & Hutchinson, M. R. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00104 · Cited by 100 · see citing works

Perineuronal nets and schizophrenia: The importance of neuronal coatings

Bitanihirwe, B. K. Y., & Woo, T.-U. W. (2014) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.03.018 · Cited by 95 · see citing works

Polymeric Nanoparticles to Control the Differentiation of Neural Stem Cells in the Subventricular Zone of the Brain

Santos, T., Ferreira, R., Maia, J., Agasse, F., Xapelli, S., Cortes, L., Bragança, J., Malva, J. O., Ferreira, L., & Bernardino, L. (2012) · ACS Nano · doi:10.1021/nn304541h · Cited by 92 · see citing works

Neuronal and astrocytic primary cilia in the mature brain

Sterpka, A., & Chen, X. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.10.002 · Cited by 80 · see citing works

Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice

Whittemore, K., Derevyanko, A., Martinez, P., Serrano, R., Pumarola, M., Bosch, F., & Blasco, M. A. (2019) · Aging · doi:10.18632/aging.101982 · Cited by 69 · see citing works

Metformin Restores Hippocampal Neurogenesis and Learning and Memory via Regulating Gut Microbiota in the Obese Mouse Model

Ma, X., Xiao, W., Li, H., Pang, P., Xue, F., Wan, L., Pei, L., & Yan, H. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.02.011 · Cited by 67 · see citing works

Central amygdala nucleus (Ce) gene expression linked to increased trait-like Ce metabolism and anxious temperament in young primates

Fox, A. S., Oler, J. A., Shelton, S. E., Nanda, S. A., Davidson, R. J., Roseboom, P. H., & Kalin, N. H. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1206723109 · Cited by 57 · see citing works

Norbin ablation results in defective adult hippocampal neurogenesis and depressive-like behavior in mice

Wang, H., Warner-Schmidt, J., Varela, S., Enikolopov, G., Greengard, P., & Flajolet, M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1510291112 · Cited by 63 · see citing works

Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB

Maimon, R., Chillon-Marinas, C., Snethlage, C. E., Singhal, S. M., McAlonis-Downes, M., Ling, K., Rigo, F., Bennett, C. F., Da Cruz, S., Hnasko, T. S., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00864-y · Cited by 62 · see citing works

Restoration of hippocampal neural precursor function by ablation of senescent cells in the aging stem cell niche

Fatt, M. P., Tran, L. M., Vetere, G., Storer, M. A., Simonetta, J. V., Miller, F. D., Frankland, P. W., & Kaplan, D. R. (2022) · Stem Cell Reports · doi:10.1016/j.stemcr.2021.12.010 · Cited by 58 · see citing works

Physical exercise and environment exploration affect synaptogenesis in adult-generated neurons in the rat dentate gyrus: possible role of BDNF

Ambrogini, P., Lattanzi, D., Ciuffoli, S., Betti, M., Fanelli, M., & Cuppini, R. (2013) · Brain Research · doi:10.1016/j.brainres.2013.08.023 · Cited by 61 · see citing works

Functional Electron Microscopy, “Flash and Freeze,” of Identified Cortical Synapses in Acute Brain Slices

Borges-Merjane, C., Kim, O., & Jonas, P. (2020) · Neuron · doi:10.1016/j.neuron.2019.12.022 · Cited by 60 · see citing works

A New Hypothesis for Alzheimer’s Disease: The Lipid Invasion Model

Rudge, J. D. (2022) · Journal of Alzheimer's Disease Reports · doi:10.3233/adr-210299 · Cited by 58 · see citing works

Plasticity in the Hippocampus, Neurogenesis and Drugs of Abuse

Avchalumov, Y., & Mandyam, C. D. (2021) · Brain Sciences · doi:10.3390/brainsci11030404 · Cited by 49 · see citing works

Neuroprotective Properties of Asiatic Acid against 5-Fluorouracil Chemotherapy in the Hippocampus in an Adult Rat Model

Welbat, J. U., Chaisawang, P., Pannangrong, W., & Wigmore, P. (2018) · Nutrients · doi:10.3390/nu10081053 · Cited by 42 · see citing works

Dysregulated Expression of Monoacylglycerol Lipase Is a Marker for Anti-Diabetic Drug Metformin-Targeted Therapy to Correct Impaired Neurogenesis and Spatial Memory in Alzheimer’s Disease

Syal, C., Kosaraju, J., Hamilton, L., Aumont, A., Chu, A., Sarma, S. N., Thomas, J., Seegobin, M., Dilworth, F. J., He, L., et al. (2020) · Theranostics · doi:10.7150/thno.44962 · Cited by 42 · see citing works

Unified theory of Alzheimer’s disease (UTAD): implications for prevention and curative therapy

Nehls, M. (2016) · Journal of Molecular Psychiatry · doi:10.1186/s40303-016-0018-8 · Cited by 41 · see citing works

Age-related decline in BubR1 impairs adult hippocampal neurogenesis

Yang, Z., Jun, H., Choi, C.-I., Yoo, K. H., Cho, C. H., Hussaini, S. M. Q., Simmons, A. J., Kim, S., van Deursen, J. M., Baker, D. J., et al. (2017) · Aging Cell · doi:10.1111/acel.12594 · Cited by 40 · see citing works

Down‐regulation of <scp>MET</scp> in hippocampal neurons of <scp>A</scp>lzheimer's disease brains

Hamasaki, H., Honda, H., Suzuki, S. O., Hokama, M., Kiyohara, Y., Nakabeppu, Y., & Iwaki, T. (2014) · Neuropathology · doi:10.1111/neup.12095 · Cited by 33 · see citing works

Epigenetic Modifications of GABAergic Interneurons Contribute to Deficits in Adult Hippocampus Neurogenesis and Depression-Like Behavior in Prenatally Stressed Mice

Zhong, H., Rong, J., Zhu, C., Liang, M., Li, Y., & Zhou, R. (2020) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyaa020 · Cited by 28 · see citing works

Magnetic Stimulation as a Therapeutic Approach for Brain Modulation and Repair: Underlying Molecular and Cellular Mechanisms

Dufor, T., Lohof, A. M., & Sherrard, R. M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216456 · Cited by 28 · see citing works

Enhancement of Hippocampal Plasticity by Physical Exercise as a Polypill for Stress and Depression: A Review

Li, A., Yau, S.-Y., Machado, S., Wang, P., Yuan, T.-F., & So, K.-F. (2019) · CNS &amp; Neurological Disorders - Drug Targets · doi:10.2174/1871527318666190308102804 · Cited by 27 · see citing works

Voluntary wheel running reverses the decrease in subventricular zone neurogenesis caused by corticosterone

Lee, J. C.-D., Yau, S.-Y., Lee, T. M. C., Lau, B. W.-M., & So, K.-F. (2016) · Cell Transplantation · doi:10.3727/096368916x692195 · Cited by 25 · see citing works

A distinct pattern of memory and attention deficiency in patients with depression

Luo, L.-L., Chen, X., Chai, Y., Li, J.-H., Zhang, M., & Zhang, J.-N. (2013) · Chinese Medical Journal · doi:10.3760/cma.j.issn.0366-6999.20122636 · Cited by 26 · see citing works

Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles

Santos, T., Ferreira, R., Quartin, E., Boto, C., Saraiva, C., Bragança, J., Peça, J., Rodrigues, C., Ferreira, L., & Bernardino, L. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.06.044 · Cited by 26 · see citing works

Short-term availability of adult-born neurons for memory encoding

Forest, J., Moreno, M., Cavelius, M., Chalençon, L., Ziessel, A., Sacquet, J., Richard, M., Didier, A., & Mandairon, N. (2019) · Nature Communications · doi:10.1038/s41467-019-13521-7 · Cited by 24 · see citing works

Activation of microglia by retroviral infection correlates with transient clearance of prions from the brain but does not change incubation time

Muth, C., Schröck, K., Madore, C., Hartmann, K., Fanek, Z., Butovsky, O., Glatzel, M., & Krasemann, S. (2017) · Brain Pathology · doi:10.1111/bpa.12441 · Cited by 23 · see citing works