Nuclear Receptor Expression Links the Circadian Clock to Metabolism

Coordination of circadian timing in mammals

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Molecular Bases for Circadian Clocks

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Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice

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Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

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The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

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Nuclear Receptors and Lipid Physiology: Opening the X-Files

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Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

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Towards a molecular understanding of adaptive thermogenesis

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PPARs and the complex journey to obesity

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Extensive and divergent circadian gene expression in liver and heart

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Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators

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A Functional Genomics Strategy Reveals Rora as a Component of the Mammalian Circadian Clock

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Dopamine Neuron Agenesis in Nurr1-Deficient Mice

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Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

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Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle

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A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders

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Minireview: Lipid Metabolism, Metabolic Diseases, and Peroxisome Proliferator-Activated Receptors

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A transcription factor response element for gene expression during circadian night

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A Web of Circadian Pacemakers

Schibler, U., & Sassone-Corsi, P. (2002) · Cell · doi:10.1016/s0092-8674(02)01225-4 · Cited by 755

ERRα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle.

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Molecular Genetics of Circadian Rhythms in Mammals

King, D. P., & Takahashi, J. S. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.713 · Cited by 551

The orphan nuclear receptor RORα regulates circadian transcription of the mammalian core-clock Bmal1

Akashi, M., & Takumi, T. (2005) · Nature Structural & Molecular Biology · doi:10.1038/nsmb925 · Cited by 491

SRC-1 and TIF2 Control Energy Balance between White and Brown Adipose Tissues

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To ERR in the estrogen pathway

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Photic Induction of mPer1 and mPer2 in Cry -Deficient Mice Lacking a Biological Clock

Okamura, H., Miyake, S., Sumi, Y., Yamaguchi, S., Yasui, A., Muijtjens, M., Hoeijmakers, J. H. J., & van der Horst, G. T. J. (1999) · Science · doi:10.1126/science.286.5449.2531 · Cited by 376

Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor α.

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PPARγ coactivator 1β/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity.

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Expression of the Peroxisome Proliferator-activated Receptor α Gene Is Stimulated by Stress and Follows a Diurnal Rhythm

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Hormone-independent Transcriptional Activation and Coactivator Binding by Novel Orphan Nuclear Receptor ERR3

Hong, H., Yang, L., & Stallcup, M. R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.32.22618 · Cited by 303

A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

Cainan, B. J., Szychowski, S., Ka-Ming Chan, F., Cado, D., & Winoto, A. (1995) · Immunity · doi:10.1016/1074-7613(95)90113-2 · Cited by 300

CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor α (PPAR α) in mice

OISHI, K., SHIRAI, H., & ISHIDA, N. (2005) · Biochemical Journal · doi:10.1042/bj20041150 · Cited by 295

Unimpaired Thymic and Peripheral T Cell Death in Mice Lacking the Nuclear Receptor NGFI-B (Nur77)

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Time- and exercise-dependent gene regulation in human skeletal muscle

Zambon, A. C., McDearmon, E. L., Salomonis, N., Vranizan, K. M., Johansen, K. L., Adey, D., Takahashi, J. S., Schambelan, M., & Conklin, B. R. (2003) · Genome Biology · doi:10.1186/gb-2003-4-10-r61 · Cited by 254

Estrogen receptor-related receptors: orphan receptors desperately seeking a ligand

Horard, B., & Vanacker, J. (2003) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0310349 · Cited by 249

Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors

Forman, B. M. (1994) · Molecular Endocrinology · doi:10.1210/me.8.9.1253 · Cited by 199

The orphan receptor Rev-erbα gene is a target of the circadian clock pacemaker

Triqueneaux, G., Thenot, S., Kakizawa, T., Antoch, M. P., Safi, R., Takahashi, J. S., Delaunay, F., & Laudet, V. (2004) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.01554 · Cited by 166

Constitutive Activation of Transcription and Binding of Coactivator by Estrogen-Related Receptors 1 and 2

Xie, W., Hong, H., Yang, N., Lin, R. J., Simon, C. M., Stallcup, M. R., & Evans, R. M. (1999) · Molecular Endocrinology · doi:10.1210/mend.13.12.0381 · Cited by 158

Adipocyte Determination- and Differentiation-dependent Factor 1/Sterol Regulatory Element-binding Protein 1c Regulates Mouse Adiponectin Expression

Seo, J. B., Moon, H. M., Noh, M. J., Lee, Y. S., Jeong, H. W., Yoo, E. J., Kim, W. S., Park, J., Youn, B., Kim, J. B., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400238200 · Cited by 143

DNA Microarray Time Series Analysis: Automated Statistical Assessment of Circadian Rhythms in Gene Expression Patterning

Straume, M. (2004) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(04)83007-6 · Cited by 139

CLOCK/BMAL1 is Involved in Lipid Metabolism via Transactivation of the Peroxisome Proliferator-activated Receptor (PPAR) Response Element

Inoue, I., Shinoda, Y., Ikeda, M., Hayashi, K., Kanazawa, K., Nomura, M., Matsunaga, T., Xu, H., Kawai, S., Awata, T., et al. (2005) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.12.169 · Cited by 137

A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb

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Conversion from white to brown adipocytes: a strategy for the control of fat mass?

Tiraby, C., & Langin, D. (2003) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2003.10.001 · Cited by 122

Identification of RVR, a novel orphan nuclear receptor that acts as a negative transcriptional regulator

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The Orphan Steroid Receptor Nur77 Family Member Nor-1 Is Essential for Early Mouse Embryogenesis

DeYoung, R. A., Baker, J. C., Cado, D., & Winoto, A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307496200 · Cited by 76

Differential Regulation of the N- myc Proto-Oncogene by RORα and RVR, Two Orphan Members of the Superfamily of Nuclear Hormone Receptors

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Transcriptional Regulation of Human Rev-erbα Gene Expression by the Orphan Nuclear Receptor Retinoic Acid-related Orphan Receptor α

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Expression of the orphan nuclear receptor ERRalpha is under circadian regulation in estrogen-responsive tissues

Horard, B., Rayet, B., Triqueneaux, G., Laudet, V., Delaunay, F., & Vanacker, J.-M. (2004) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0330087 · Cited by 59

Identification of Reverbα as a Novel RORα Target Gene

Delerive, P., Chin, W. W., & Suen, C. S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202979200 · Cited by 58

Modulation of the Far-Upstream Enhancer of the Rat α-Fetoprotein Gene by Members of the RORα, Rev-erbα, and Rev-erbβ Groups of Monomeric Orphan Nuclear Receptors

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Sleep and the endocrine system: new associations to old diseases

Boethel, C. D. (2002) · Current Opinion in Pulmonary Medicine · doi:10.1097/00063198-200211000-00003 · Cited by 36

Central and Peripheral Circadian Clocks in Mammals

Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153128 · Cited by 2,265

Circadian integration of metabolism and energetics

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Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

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The genetics of mammalian circadian order and disorder: implications for physiology and disease

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Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

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