Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

Sancak, Yasemin, Bar-Peled, Liron, Zoncu, Roberto, Markhard, Andrew L., Nada, Shigeyuki, Sabatini, David M.·2010·Cell

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Items 201–300 of 1,007

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  3. Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot
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  4. Molecular regulation of autophagy machinery by mTOR‐dependent and ‐independent pathways
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  7. Nutrient Regulation of the mTOR Complex 1 Signaling Pathway
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  8. A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS
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  10. Protein damage, repair and proteolysis
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  12. AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3
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  13. Translation deregulation in human disease
    Soroush Tahmasebi, Arkady Khoutorsky, Michael B. Mathews, Nahum Sonenberg · 2018 · Nature Reviews Molecular Cell Biology
  14. mTORC1 signaling controls multiple steps in ribosome biogenesis
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  15. Emerging role of autophagy in kidney function, diseases and aging
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  16. Molecules and their functions in autophagy
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  17. KRas Localizes to the Plasma Membrane by Spatial Cycles of Solubilization, Trapping and Vesicular Transport
    Schmick, Malte, Vartak, Nachiket, Papke, Björn, Kovacevic, Marija, Truxius, Dina C., Rossmannek, Lisaweta, Bastiaens, Philippe I.H. · 2014 · Cell
  18. Targeting autophagy to overcome drug resistance: further developments
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    Marco Alessandro Pierotti, Franco Berrino, Manuela Gariboldi, Cecilia C. Melani, Angela Mogavero, Tiziana Negri, Patrizia Pasanisi, Silvana Pilotti · 2012 · Oncogene
  20. Amino acid auxotrophy as a system of immunological control nodes
    Peter J. Murray · 2016 · Nature Immunology
  21. Signaling networks in immunometabolism
    Jordy Saravia, Jana L. Raynor, Nicole M. Chapman, Seon Ah Lim, Hongbo Chi · 2020 · Cell Research
  22. Autophagy regulation and its role in cancer
    Séverine Lorin, Ahmed Hamaï, Maryam Mehrpour, Patrice Codogno · 2013 · Seminars in Cancer Biology
  23. mTOR Drives Its Own Activation via SCFβTrCP-Dependent Degradation of the mTOR Inhibitor DEPTOR
    Daming Gao, Hiroyuki Inuzuka, Meng-Kwang Marcus Tan, Hidefumi Fukushima, Jason W. Locasale, Pengda Liu, Lixin Wan, Bo Zhai, Y. Rebecca Chin, Shavali Shaik et al. · 2011 · Molecular Cell
  24. Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagy
    Kristan E. van der Vos, Pernilla Eliasson, Tassula Proikas‐Cezanne, Stephin J. Vervoort, Ruben van Boxtel, Marrit Putker, Iris J. van Zutphen, Mario Mauthe, Sebastian Zellmer, Cornelieke E. G. M. Pals et al. · 2012 · Nature Cell Biology
  25. The crucial impact of lysosomes in aging and longevity
    Didac Carmona‐Gutiérrez, Adam L. Hughes, Frank Madeo, Christoph Ruckenstuhl · 2016 · Ageing Research Reviews
  26. Autophagy, lipophagy and lysosomal lipid storage disorders
    Carl Ward, Nuria Martínez-López, Elsje G. Otten, Bernadette Carroll, Dorothea Maetzel, Rajat Singh, Sovan Sarkar, Viktor I. Korolchuk · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  27. Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
    Sung Min Son, So Jung Park, Huikyong Lee, Farah H. Siddiqi, Jong Eun Lee, Fiona M. Menzies, David Chaim Rubinsztein · 2018 · Cell Metabolism
  28. p62: a versatile multitasker takes on cancer
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  29. Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis
    Giovanni Quarato, Cliff S. Guy, Christy R. Grace, Fabien Llambi, Amanda Nourse, Diego A. Rodríguez, Randall Wakefield, Sharon Frase, Tudor Moldoveanu, Douglas R. Green · 2016 · Molecular Cell
  30. A comprehensive map of the mTOR signaling network
    Étienne Caron, Samik Ghosh, Yukiko Matsuoka, Dariel Ashton‐Beaucage, Marc Therrien, Sébastien Lemieux, Claude Perreault, Philippe P. Roux, Hiroaki Kitano · 2010 · Molecular Systems Biology
  31. PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer
    Vito W. Rebecca, Michael C. Nicastri, Colin Fennelly, Cynthia I. Chude, Julie S. Barber-Rotenberg, Amruta Mukund Ronghe, Quentin W. Mcafee, Noel P. McLaughlin, Gao Zhang, Aaron R. Goldman et al. · 2018 · Cancer Discovery
  32. Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo
    Joon-Ho Sheen, Roberto Zoncu, Dohoon Kim, David M. Sabatini · 2011 · Cancer Cell
  33. Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation
    Anyuan He, Xiaowen Chen, Min Tan, Yali Chen, Dongliang Lu, Xiangyu Zhang, John M. Dean, Babak Razani, Irfan J. Lodhi · 2020 · Molecular Cell
  34. Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A
    Wong, Pui-Mun, Feng, Yan, Wang, Junru, Shi, Rong, Jiang, Xuejun · 2015 · Nature Communications
  35. Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis
    Jessica T. Root, Paola Merino, Austin Nuckols, Michelle A. Johnson, Thomas L. Kukar · 2021 · Neurobiology of Disease
  36. Amino Acid Signaling in TOR Activation
    Joungmok Kim, Kun‐Liang Guan · 2011 · Annual Review of Biochemistry
  37. Multistep regulation of TFEB by MTORC1
    S. Vega-Rubín-de-Celis, Samuel Peña-Llopis, Meghan Konda, J. Brugarolas · 2017 · Autophagy
  38. Metabolic regulation of osteoclast differentiation and function
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  40. A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming
    Jaeil Han, Collette A. LaVigne, Benjamin T. Jones, He Zhang, Frank A Gillett, Joshua T. Mendell · 2020 · Science
  41. Glutamine and asparagine activate mTORC1 independently of Rag GTPases
    Delong Meng, Qianmei Yang, Huanyu Wang, Chase H. Melick, Rishika Navlani, Anderson R. Frank, Jenna L. Jewell · 2020 · Journal of Biological Chemistry
  42. The emerging roles of vacuolar-type ATPase-dependent Lysosomal acidification in neurodegenerative diseases
    Qiao‐Yun Song, Bo Meng, Haidong Xu, Zixu Mao · 2020 · Translational Neurodegeneration
  43. Staying alive
    James R. Valcourt, Johanna M. S. Lemons, Erin M. Haley, Mina L. Kojima, Olukunle O. Demuren, Hilary A. Coller · 2012 · Cell Cycle
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    Colm J. Ryan, Assen Roguev, Kristin L. Patrick, Jiewei Xu, Harlizawati Jahari, Zongtian Tong, Pedro Beltrão, Michael Shales, Hong Qu, Sean R. Collins et al. · 2012 · Molecular Cell
  45. Autophagy signal transduction by ATG proteins: from hierarchies to networks
    Sebastian Wesselborg, Björn Stork · 2015 · Cellular and Molecular Life Sciences
  46. Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR
    Jordan Gallinetti, Eylul Harputlugil, James R. Mitchell · 2012 · Biochemical Journal
  47. Identification of prostate cancer biomarkers in urinary exosomes
    Anders Øverbye, Tore Skotland, Christian Jeffrey Koehler, Bernd Thiede, Therese Seierstad, Viktor Berge, Kirsten Sandvig, Alicia Llorente · 2015 · Oncotarget
  48. Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway
    Ruud H. M. Wijdeven, Hans Janssen, Leila Nahidiazar, Lennert Janssen, Kees Jalink, Ilana Berlin, Jacques Neefjes · 2016 · Nature Communications
  49. Investigation of endosome and lysosome biology by ultra pH-sensitive nanoprobes
    Chensu Wang, Tian Zhao, Yang Li, Gang Huang, Michael A. White, Jinming Gao · 2016 · Advanced Drug Delivery Reviews
  50. Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
    Zandra E. Walton, Chirag H. Patel, Rebekah C. Brooks, Yongjun Yu, Arig Ibrahim‐Hashim, Malini Riddle, Alessandra Porcu, Tianying Jiang, Brett Logan Ecker, Feven Tameire et al. · 2018 · Cell
  51. Targeting lysosomes in human disease: from basic research to clinical applications
    Cao, Mengdie, Luo, Xiangyuan, Wu, Kongming, He, Xingxing · 2021 · Signal Transduction and Targeted Therapy
  52. Multiple amino acid sensing inputs to mTORC1
    Mitsugu Shimobayashi, M. Hall · 2015 · Cell Research
  53. Targeting glutamine transport to suppress melanoma cell growth
    Qian Wang, Kimberley A. Beaumont, Nicholas James Otte, Josep S. Font, Charles G. Bailey, Michelle van Geldermalsen, Danae M. Sharp, Jessamy C. Tiffen, Renae M. Ryan, Mika Jormakka et al. · 2014 · International Journal of Cancer
  54. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling
    Peng, Min, Yin, Na, Li, Ming O. · 2014 · Cell
  55. Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin
    Winbanks, Catherine E., Weeks, Kate L., Thomson, Rachel E., Sepulveda, Patricio V., Beyer, Claudia, Qian, Hongwei, Chen, Justin L., Allen, James M., Lancaster, Graeme I., Febbraio, Mark A. et al. · 2012 · Journal of Cell Biology
  56. AMPK directly activates mTORC2 to promote cell survival during acute energetic stress
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  57. AMPK–mTOR Signaling and Cellular Adaptations in Hypoxia
    Yoomi Chun, Joungmok Kim · 2021 · International Journal of Molecular Sciences
  58. Autophagy as a modulator of cell death machinery
    Masayuki Noguchi, Noriyuki Hirata, Tsutomu Tanaka, Futoshi Suizu, Hiroshi Nakajima, John A. Chiorini · 2020 · Cell Death and Disease
  59. Metabolic Stress Controls mTORC1 Lysosomal Localization and Dimerization by Regulating the TTT-RUVBL1/2 Complex
    Kim, Sang Gyun, Hoffman, Gregory R., Poulogiannis, George, Buel, Gwen R., Jang, Young Jin, Lee, Ki Won, Kim, Bo-Yeon, Erikson, Raymond L., Cantley, Lewis C., Choo, Andrew Y. et al. · 2013 · Molecular Cell
  60. Akt and mTOR in B Cell Activation and Differentiation
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  61. Role of amino acid transporters in amino acid sensing
    Peter Maving Taylor · 2013 · American Journal of Clinical Nutrition
  62. NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer
    Rajendra Karki, Si Ming Man, R. K. Subbarao Malireddi, Sannula Kesavardhana, Qifan Zhu, Amanda R. Burton, Bhesh Raj Sharma, Xiaopeng Qi, S. William Pelletier, Peter Vogel et al. · 2016 · Nature
  63. Phosphoinositide-3 Kinase Signaling in Cardiac Hypertrophy and Heart Failure
    Toshinori Aoyagi, Takashi Matsui · 2011 · Current Pharmaceutical Design
  64. MenTORing Immunity: mTOR Signaling in the Development and Function of Tissue-Resident Immune Cells
    Russell G. Jones, Edward J. Pearce · 2017 · Immunity
  65. Autophagy and microtubules - new story, old players
    Mackeh, Rafah, Perdiz, Daniel, Lorin, Séverine, Codogno, Patrice, Poüs, Christian · 2013 · Journal of Cell Science
  66. Lysosomal Function and Dysfunction: Mechanism and Disease
    Patricia Boya · 2011 · Antioxidants and Redox Signaling
  67. Structural basis for the docking of mTORC1 on the lysosomal surface
    K. B. Rogala, X. Gu, Jibril F. Kedir, Monther Abu-Remaileh, Laura F. Bianchi, Alexia M S Bottino, Rikke Dueholm, Anna Niehaus, D. Overwijn, Ange-Célia Priso Fils et al. · 2019 · Science
  68. AMPK and autophagy in glucose/glycogen metabolism
    Joohun Ha, Kun‐Liang Guan, Joungmok Kim · 2015 · Molecular Aspects of Medicine
  69. Autophagy and the Cell Cycle: A Complex Landscape
    Søs Grønbæk Mathiassen, Daniela De Zio, Francesco Cecconi · 2017 · Frontiers in Oncology
  70. Regulation and function of V-ATPases in physiology and disease
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  71. Role of methionine on epigenetic modification of DNA methylation and gene expression in animals
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  72. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex
    Liang, Ning, Zhang, Chi, Dill, Patricia, Panasyuk, Ganna, Pion, Delphine, Koka, Vonda, Gallazzini, Morgan, Olson, Eric N., Lam, Hilaire, Henske, Elizabeth P. et al. · 2014 · Journal of Experimental Medicine
  73. A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles
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  74. Regulation of Muscle Protein Synthesis and the Effects of Catabolic States
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  75. Localization of mTORC2 activity inside cells
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  76. Autophagy: The Last Defense against Cellular Nutritional Stress
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  77. Research progress of mTOR inhibitors
    Yifan Chen, Xiao‐Ping Zhou · 2020 · European Journal of Medicinal Chemistry
  78. Autophagy in Alzheimer’s disease
    Zare-shahabadi, Ameneh, Masliah, Eliezer, Johnson, Gail V.W., Rezaei, Nima · 2015 · Reviews in the Neurosciences
  79. Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
    J. Okosun, Rachel L. Wolfson, Jun Wang, Shamzah Araf, Lucy Wilkins, Brian M. Castellano, L. Escudero-Ibarz, Ahad Al Seraihi, J. Richter, S. Bernhart et al. · 2015 · Nature Genetics
  80. Oncogenic MYC Activates a Feedforward Regulatory Loop Promoting Essential Amino Acid Metabolism and Tumorigenesis
    Ming Yue, Jue Jiang, Peng Gao, Hudan Liu, Guoliang Qing · 2017 · Cell Reports
  81. LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation
    Ruth Milkereit, Avinash K. Persaud, Liviu Vanoaica, Adriano Guetg, François Verrey, Daniela Rotin · 2015 · Nature Communications
  82. mTOR-Dependent Cell Survival Mechanisms
    Clarey Hung, Luisa García-Haro, C. A. Sparks, David A. Guertin · 2012 · Cold Spring Harbor Perspectives in Biology
  83. Organelle-Specific Initiation of Autophagy
    Sica, Valentina, Galluzzi, Lorenzo, Bravo-San Pedro, José Manuel, Izzo, Valentina, Maiuri, Maria Chiara, Kroemer, Guido · 2015 · Molecular Cell
  84. The role of TRPMLs in endolysosomal trafficking and function
    Kartik Venkatachalam, Ching‐On Wong, Michael X. Zhu · 2014 · Cell Calcium
  85. Metformin extends C. elegans lifespan through lysosomal pathway
    Jie Chen, Yuhui Ou, Yi Li, Shumei Hu, Li-Wa Shao, Ying Liu · 2017 · eLife
  86. Lysosomal size matters
    Mariana E. G. de Araújo, Gudrun Liebscher, Michael W. Hess, Lukas Alfons Huber · 2019 · Traffic
  87. TORC1 Regulates Endocytosis via Npr1-Mediated Phosphoinhibition of a Ubiquitin Ligase Adaptor
    Jason A. MacGurn, Pi-Chiang Hsu, Marcus Bustamante Smolka, Scott D. Emr · 2011 · Cell
  88. T‐cell metabolism governing activation, proliferation and differentiation; a modular view
    Sarah Dimeloe, Anne-Valérie Burgener-Gasser, Jasmin Grählert, Christoph Hess · 2016 · Immunology
  89. The renal Fanconi syndrome in cystinosis: pathogenic insights and therapeutic perspectives
    Stéphanie Cherqui, Pierre J. Courtoy · 2016 · Nature Reviews Nephrology
  90. The mTORC1 signaling network senses changes in cellular purine nucleotide levels
    Gerta Hoxhaj, J. Hughes-Hallett, Rebecca C. Timson, Erika Ilagan, Min Yuan, J. Asara, I. Ben-Sahra, B. Manning · 2017 · Cell Reports
  91. NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C
    Davis, Oliver B., Shin, Hijai R., Lim, Chun-Yan, Wu, Emma Y., Kukurugya, Matthew, Maher, Claire F., Perera, Rushika M., Ordonez, M. Paulina, Zoncu, Roberto · 2021 · Developmental Cell
  92. An Extended Proteome Map of the Lysosomal Membrane Reveals Novel Potential Transporters
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  93. Endocytosis and Autophagy: Exploitation or Cooperation?
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  94. The lysosomal Rag-Ragulator complex licenses RIPK1– and caspase-8–mediated pyroptosis by Yersinia
    Zengzhang Zheng, Wanyan Deng, Yang Bai, Rui Miao, Shenglin Mei, Zhibin Zhang, Youdong Pan, Yi Wang, Rui Min, Fan Deng et al. · 2021 · Science
  95. Distribution and Functions of Sterols and Sphingolipids
    J. Thomas Hannich, Kyohei Umebayashi, Howard Riezman · 2011 · Cold Spring Harbor Perspectives in Biology
  96. The G Protein-Coupled Taste Receptor T1R1/T1R3 Regulates mTORC1 and Autophagy
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  97. Inhibition of the Mechanistic Target of Rapamycin (mTOR)–Rapamycin and Beyond
    Dudley W. Lamming · 2016 · Cold Spring Harbor Perspectives in Medicine
  98. The lysosome: a crucial hub for AMPK and mTORC1 signalling
    Bernadette Carroll, Elaine A. Dunlop · 2017 · Biochemical Journal
  99. Regulation of mRNA Translation by Signaling Pathways
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  100. Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex
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