Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Sancak, Yasemin, Bar-Peled, Liron, Zoncu, Roberto, Markhard, Andrew L., Nada, Shigeyuki, Sabatini, David M.·2010·Cell
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- Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the SpotD. Goberdhan, C. Wilson, A. Harris · 2016 · Cell Metabolism
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- Nutrient Regulation of the mTOR Complex 1 Signaling PathwaySang Gyun Kim, Gwen R. Buel, John Blenis · 2013 · Molecules and Cells
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- Translation deregulation in human diseaseSoroush Tahmasebi, Arkady Khoutorsky, Michael B. Mathews, Nahum Sonenberg · 2018 · Nature Reviews Molecular Cell Biology
- mTORC1 signaling controls multiple steps in ribosome biogenesisIadevaia, Valentina, Liu, Rui, Proud, Christopher G. · 2014 · Seminars in Cell & Developmental Biology
- Emerging role of autophagy in kidney function, diseases and agingTobias Bruno Huber, Charles L. Edelstein, Björn Hartleben, Ken Inoki, Man Jiang, Daisuke Koya, Shinji Kume, Wilfred Lieberthal, Nicolas Pallet, Alejandro Quiroga et al. · 2012 · Autophagy
- Molecules and their functions in autophagyJong-Ok Pyo, Jihoon Nah, Yong‐Keun Jung · 2012 · Experimental & Molecular Medicine
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- Amino acid auxotrophy as a system of immunological control nodesPeter J. Murray · 2016 · Nature Immunology
- Signaling networks in immunometabolismJordy Saravia, Jana L. Raynor, Nicole M. Chapman, Seon Ah Lim, Hongbo Chi · 2020 · Cell Research
- Autophagy regulation and its role in cancerSéverine Lorin, Ahmed Hamaï, Maryam Mehrpour, Patrice Codogno · 2013 · Seminars in Cancer Biology
- mTOR Drives Its Own Activation via SCFβTrCP-Dependent Degradation of the mTOR Inhibitor DEPTORDaming Gao, Hiroyuki Inuzuka, Meng-Kwang Marcus Tan, Hidefumi Fukushima, Jason W. Locasale, Pengda Liu, Lixin Wan, Bo Zhai, Y. Rebecca Chin, Shavali Shaik et al. · 2011 · Molecular Cell
- Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagyKristan E. van der Vos, Pernilla Eliasson, Tassula Proikas‐Cezanne, Stephin J. Vervoort, Ruben van Boxtel, Marrit Putker, Iris J. van Zutphen, Mario Mauthe, Sebastian Zellmer, Cornelieke E. G. M. Pals et al. · 2012 · Nature Cell Biology
- The crucial impact of lysosomes in aging and longevityDidac Carmona‐Gutiérrez, Adam L. Hughes, Frank Madeo, Christoph Ruckenstuhl · 2016 · Ageing Research Reviews
- Autophagy, lipophagy and lysosomal lipid storage disordersCarl Ward, Nuria Martínez-López, Elsje G. Otten, Bernadette Carroll, Dorothea Maetzel, Rajat Singh, Sovan Sarkar, Viktor I. Korolchuk · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme ASung Min Son, So Jung Park, Huikyong Lee, Farah H. Siddiqi, Jong Eun Lee, Fiona M. Menzies, David Chaim Rubinsztein · 2018 · Cell Metabolism
- p62: a versatile multitasker takes on cancerJorge Moscat, Maria Teresa Díaz-Meco · 2012 · Trends in Biochemical Sciences
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- A comprehensive map of the mTOR signaling networkÉtienne Caron, Samik Ghosh, Yukiko Matsuoka, Dariel Ashton‐Beaucage, Marc Therrien, Sébastien Lemieux, Claude Perreault, Philippe P. Roux, Hiroaki Kitano · 2010 · Molecular Systems Biology
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- Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 ActivationAnyuan He, Xiaowen Chen, Min Tan, Yali Chen, Dongliang Lu, Xiangyu Zhang, John M. Dean, Babak Razani, Irfan J. Lodhi · 2020 · Molecular Cell
- Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2AWong, Pui-Mun, Feng, Yan, Wang, Junru, Shi, Rong, Jiang, Xuejun · 2015 · Nature Communications
- Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosisJessica T. Root, Paola Merino, Austin Nuckols, Michelle A. Johnson, Thomas L. Kukar · 2021 · Neurobiology of Disease
- Amino Acid Signaling in TOR ActivationJoungmok Kim, Kun‐Liang Guan · 2011 · Annual Review of Biochemistry
- Multistep regulation of TFEB by MTORC1S. Vega-Rubín-de-Celis, Samuel Peña-Llopis, Meghan Konda, J. Brugarolas · 2017 · Autophagy
- Metabolic regulation of osteoclast differentiation and functionYoriko Indo, Sunao Takeshita, Kiyo‐aki Ishii, Takayuki Hoshii, Hiroyuki Aburatani, Atsushi Hirao, Kyoji Ikeda · 2013 · Journal of Bone and Mineral Research
- Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiationKristen N. Pollizzi, Im‐Hong Sun, Chirag H. Patel, Ying-Chun Lo, Min Hee Oh, Adam Tully Waickman, Ada J Tam, Richard L. Blosser, Jiayu Wen, Greg M. Delgoffe et al. · 2016 · Nature Immunology
- A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimmingJaeil Han, Collette A. LaVigne, Benjamin T. Jones, He Zhang, Frank A Gillett, Joshua T. Mendell · 2020 · Science
- Glutamine and asparagine activate mTORC1 independently of Rag GTPasesDelong Meng, Qianmei Yang, Huanyu Wang, Chase H. Melick, Rishika Navlani, Anderson R. Frank, Jenna L. Jewell · 2020 · Journal of Biological Chemistry
- The emerging roles of vacuolar-type ATPase-dependent Lysosomal acidification in neurodegenerative diseasesQiao‐Yun Song, Bo Meng, Haidong Xu, Zixu Mao · 2020 · Translational Neurodegeneration
- Staying aliveJames R. Valcourt, Johanna M. S. Lemons, Erin M. Haley, Mina L. Kojima, Olukunle O. Demuren, Hilary A. Coller · 2012 · Cell Cycle
- Hierarchical Modularity and the Evolution of Genetic Interactomes across SpeciesColm J. Ryan, Assen Roguev, Kristin L. Patrick, Jiewei Xu, Harlizawati Jahari, Zongtian Tong, Pedro Beltrão, Michael Shales, Hong Qu, Sean R. Collins et al. · 2012 · Molecular Cell
- Autophagy signal transduction by ATG proteins: from hierarchies to networksSebastian Wesselborg, Björn Stork · 2015 · Cellular and Molecular Life Sciences
- Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TORJordan Gallinetti, Eylul Harputlugil, James R. Mitchell · 2012 · Biochemical Journal
- Identification of prostate cancer biomarkers in urinary exosomesAnders Øverbye, Tore Skotland, Christian Jeffrey Koehler, Bernd Thiede, Therese Seierstad, Viktor Berge, Kirsten Sandvig, Alicia Llorente · 2015 · Oncotarget
- Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathwayRuud H. M. Wijdeven, Hans Janssen, Leila Nahidiazar, Lennert Janssen, Kees Jalink, Ilana Berlin, Jacques Neefjes · 2016 · Nature Communications
- Investigation of endosome and lysosome biology by ultra pH-sensitive nanoprobesChensu Wang, Tian Zhao, Yang Li, Gang Huang, Michael A. White, Jinming Gao · 2016 · Advanced Drug Delivery Reviews
- Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTORZandra E. Walton, Chirag H. Patel, Rebekah C. Brooks, Yongjun Yu, Arig Ibrahim‐Hashim, Malini Riddle, Alessandra Porcu, Tianying Jiang, Brett Logan Ecker, Feven Tameire et al. · 2018 · Cell
- Targeting lysosomes in human disease: from basic research to clinical applicationsCao, Mengdie, Luo, Xiangyuan, Wu, Kongming, He, Xingxing · 2021 · Signal Transduction and Targeted Therapy
- Multiple amino acid sensing inputs to mTORC1Mitsugu Shimobayashi, M. Hall · 2015 · Cell Research
- Targeting glutamine transport to suppress melanoma cell growthQian Wang, Kimberley A. Beaumont, Nicholas James Otte, Josep S. Font, Charles G. Bailey, Michelle van Geldermalsen, Danae M. Sharp, Jessamy C. Tiffen, Renae M. Ryan, Mika Jormakka et al. · 2014 · International Journal of Cancer
- Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signalingPeng, Min, Yin, Na, Li, Ming O. · 2014 · Cell
- Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatinWinbanks, Catherine E., Weeks, Kate L., Thomson, Rachel E., Sepulveda, Patricio V., Beyer, Claudia, Qian, Hongwei, Chen, Justin L., Allen, James M., Lancaster, Graeme I., Febbraio, Mark A. et al. · 2012 · Journal of Cell Biology
- AMPK directly activates mTORC2 to promote cell survival during acute energetic stressDubek Kazyken, Brian Magnuson, Çağrı Bodur, Hugo A. Acosta-Jaquez, Deqiang Zhang, Xin Tong, Tammy M. Barnes, Gabrielle K. Steinl, Nicole Patterson, Christopher H. Altheim et al. · 2019 · Science Signaling
- AMPK–mTOR Signaling and Cellular Adaptations in HypoxiaYoomi Chun, Joungmok Kim · 2021 · International Journal of Molecular Sciences
- Autophagy as a modulator of cell death machineryMasayuki Noguchi, Noriyuki Hirata, Tsutomu Tanaka, Futoshi Suizu, Hiroshi Nakajima, John A. Chiorini · 2020 · Cell Death and Disease
- Metabolic Stress Controls mTORC1 Lysosomal Localization and Dimerization by Regulating the TTT-RUVBL1/2 ComplexKim, Sang Gyun, Hoffman, Gregory R., Poulogiannis, George, Buel, Gwen R., Jang, Young Jin, Lee, Ki Won, Kim, Bo-Yeon, Erikson, Raymond L., Cantley, Lewis C., Choo, Andrew Y. et al. · 2013 · Molecular Cell
- Akt and mTOR in B Cell Activation and DifferentiationJose J. Limon, David A. Fruman · 2012 · Frontiers in Immunology
- Role of amino acid transporters in amino acid sensingPeter Maving Taylor · 2013 · American Journal of Clinical Nutrition
- NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancerRajendra Karki, Si Ming Man, R. K. Subbarao Malireddi, Sannula Kesavardhana, Qifan Zhu, Amanda R. Burton, Bhesh Raj Sharma, Xiaopeng Qi, S. William Pelletier, Peter Vogel et al. · 2016 · Nature
- Phosphoinositide-3 Kinase Signaling in Cardiac Hypertrophy and Heart FailureToshinori Aoyagi, Takashi Matsui · 2011 · Current Pharmaceutical Design
- MenTORing Immunity: mTOR Signaling in the Development and Function of Tissue-Resident Immune CellsRussell G. Jones, Edward J. Pearce · 2017 · Immunity
- Autophagy and microtubules - new story, old playersMackeh, Rafah, Perdiz, Daniel, Lorin, Séverine, Codogno, Patrice, Poüs, Christian · 2013 · Journal of Cell Science
- Lysosomal Function and Dysfunction: Mechanism and DiseasePatricia Boya · 2011 · Antioxidants and Redox Signaling
- Structural basis for the docking of mTORC1 on the lysosomal surfaceK. B. Rogala, X. Gu, Jibril F. Kedir, Monther Abu-Remaileh, Laura F. Bianchi, Alexia M S Bottino, Rikke Dueholm, Anna Niehaus, D. Overwijn, Ange-Célia Priso Fils et al. · 2019 · Science
- AMPK and autophagy in glucose/glycogen metabolismJoohun Ha, Kun‐Liang Guan, Joungmok Kim · 2015 · Molecular Aspects of Medicine
- Autophagy and the Cell Cycle: A Complex LandscapeSøs Grønbæk Mathiassen, Daniela De Zio, Francesco Cecconi · 2017 · Frontiers in Oncology
- Regulation and function of V-ATPases in physiology and diseaseMichael P. Collins, Michael D. Forgac · 2020 · Biochimica et Biophysica Acta (BBA) - Biomembranes
- Role of methionine on epigenetic modification of DNA methylation and gene expression in animalsNaifeng Zhang · 2017 · Animal nutrition
- Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complexLiang, Ning, Zhang, Chi, Dill, Patricia, Panasyuk, Ganna, Pion, Delphine, Koka, Vonda, Gallazzini, Morgan, Olson, Eric N., Lam, Hilaire, Henske, Elizabeth P. et al. · 2014 · Journal of Experimental Medicine
- A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling RolesVito W. Rebecca, Michael C. Nicastri, Noel P. McLaughlin, Colin Fennelly, Quentin W. Mcafee, Amruta Mukund Ronghe, Michel Nofal, Chun-Yan Lim, Eric S. Witze, Cynthia I. Chude et al. · 2017 · Cancer Discovery
- Regulation of Muscle Protein Synthesis and the Effects of Catabolic StatesBradley S. Gordon, A. Kelleher, S. Kimball · 2013 · International Journal of Biochemistry and Cell Biology
- Localization of mTORC2 activity inside cellsM. Ebner, Benjamin Sinkovics, M. Szczygieł, Daniela Ribeiro, I. Yudushkin · 2017 · Journal of Cell Biology
- Autophagy: The Last Defense against Cellular Nutritional StressLong He, Jie Zhang, Jinshan Zhao, Ning Ma, Sung Woo Kim, Shiyan Qiao, Xi Ma · 2018 · Advances in Nutrition
- Research progress of mTOR inhibitorsYifan Chen, Xiao‐Ping Zhou · 2020 · European Journal of Medicinal Chemistry
- Autophagy in Alzheimer’s diseaseZare-shahabadi, Ameneh, Masliah, Eliezer, Johnson, Gail V.W., Rezaei, Nima · 2015 · Reviews in the Neurosciences
- Recurrent mTORC1-activating RRAGC mutations in follicular lymphomaJ. Okosun, Rachel L. Wolfson, Jun Wang, Shamzah Araf, Lucy Wilkins, Brian M. Castellano, L. Escudero-Ibarz, Ahad Al Seraihi, J. Richter, S. Bernhart et al. · 2015 · Nature Genetics
- Oncogenic MYC Activates a Feedforward Regulatory Loop Promoting Essential Amino Acid Metabolism and TumorigenesisMing Yue, Jue Jiang, Peng Gao, Hudan Liu, Guoliang Qing · 2017 · Cell Reports
- LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activationRuth Milkereit, Avinash K. Persaud, Liviu Vanoaica, Adriano Guetg, François Verrey, Daniela Rotin · 2015 · Nature Communications
- mTOR-Dependent Cell Survival MechanismsClarey Hung, Luisa García-Haro, C. A. Sparks, David A. Guertin · 2012 · Cold Spring Harbor Perspectives in Biology
- Organelle-Specific Initiation of AutophagySica, Valentina, Galluzzi, Lorenzo, Bravo-San Pedro, José Manuel, Izzo, Valentina, Maiuri, Maria Chiara, Kroemer, Guido · 2015 · Molecular Cell
- The role of TRPMLs in endolysosomal trafficking and functionKartik Venkatachalam, Ching‐On Wong, Michael X. Zhu · 2014 · Cell Calcium
- Metformin extends C. elegans lifespan through lysosomal pathwayJie Chen, Yuhui Ou, Yi Li, Shumei Hu, Li-Wa Shao, Ying Liu · 2017 · eLife
- Lysosomal size mattersMariana E. G. de Araújo, Gudrun Liebscher, Michael W. Hess, Lukas Alfons Huber · 2019 · Traffic
- TORC1 Regulates Endocytosis via Npr1-Mediated Phosphoinhibition of a Ubiquitin Ligase AdaptorJason A. MacGurn, Pi-Chiang Hsu, Marcus Bustamante Smolka, Scott D. Emr · 2011 · Cell
- T‐cell metabolism governing activation, proliferation and differentiation; a modular viewSarah Dimeloe, Anne-Valérie Burgener-Gasser, Jasmin Grählert, Christoph Hess · 2016 · Immunology
- The renal Fanconi syndrome in cystinosis: pathogenic insights and therapeutic perspectivesStéphanie Cherqui, Pierre J. Courtoy · 2016 · Nature Reviews Nephrology
- The mTORC1 signaling network senses changes in cellular purine nucleotide levelsGerta Hoxhaj, J. Hughes-Hallett, Rebecca C. Timson, Erika Ilagan, Min Yuan, J. Asara, I. Ben-Sahra, B. Manning · 2017 · Cell Reports
- NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type CDavis, Oliver B., Shin, Hijai R., Lim, Chun-Yan, Wu, Emma Y., Kukurugya, Matthew, Maher, Claire F., Perera, Rushika M., Ordonez, M. Paulina, Zoncu, Roberto · 2021 · Developmental Cell
- An Extended Proteome Map of the Lysosomal Membrane Reveals Novel Potential TransportersAgnès Chapel, Sylvie Kieffer‐Jaquinod, Corinne Sagné, Quentin Verdon, Corinne Ivaldi, Mourad Mellal, Jaqueline Thirion, Michel Jadot, Christophe Bruley, Jérôme Garin et al. · 2013 · Molecular & Cellular Proteomics
- Endocytosis and Autophagy: Exploitation or Cooperation?Tooze, S. A., Abada, A., Elazar, Z. · 2014 · Cold Spring Harbor Perspectives in Biology
- The lysosomal Rag-Ragulator complex licenses RIPK1– and caspase-8–mediated pyroptosis by YersiniaZengzhang Zheng, Wanyan Deng, Yang Bai, Rui Miao, Shenglin Mei, Zhibin Zhang, Youdong Pan, Yi Wang, Rui Min, Fan Deng et al. · 2021 · Science
- Distribution and Functions of Sterols and SphingolipidsJ. Thomas Hannich, Kyohei Umebayashi, Howard Riezman · 2011 · Cold Spring Harbor Perspectives in Biology
- The G Protein-Coupled Taste Receptor T1R1/T1R3 Regulates mTORC1 and AutophagyEric Wauson, Elma Zaganjor, A-Young Lee, Marcy L. Guerra, Anwesha B. Ghosh, Angie L. Bookout, Chris P. Chambers, Arif Jivan, Kathleen McGlynn, Michele R. Hutchison et al. · 2012 · Molecular Cell
- Inhibition of the Mechanistic Target of Rapamycin (mTOR)–Rapamycin and BeyondDudley W. Lamming · 2016 · Cold Spring Harbor Perspectives in Medicine
- The lysosome: a crucial hub for AMPK and mTORC1 signallingBernadette Carroll, Elaine A. Dunlop · 2017 · Biochemical Journal
- Regulation of mRNA Translation by Signaling PathwaysIvan Topisirović, I. Topisirovic · 2012 · Cold Spring Harbor Perspectives in Biology
- Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplexZhicheng Cui, Gennaro Napolitano, Mariana E. G. de Araújo, Alessandra Esposito, Jlenia Monfregola, Lukas Alfons Huber, Andrea Ballabio, James H. Hurley · 2023 · Nature