Hedgehog Partial Agonism Drives Warburg-like Metabolism in Muscle and Brown Fat

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A paracrine requirement for hedgehog signalling in cancer

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Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth

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Gli Proteins in Development and Disease

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Mechanisms and functions of Hedgehog signalling across the metazoa

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Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

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Inhibiting the Hedgehog Pathway in Patients with the Basal-Cell Nevus Syndrome

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Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis

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Hedgehog beyond medulloblastoma and basal cell carcinoma

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The Hedgehog's tale: developing strategies for targeting cancer

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Primary cilia regulate mTORC1 activity and cell size through Lkb1

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Purmorphamine activates the Hedgehog pathway by targeting Smoothened

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Drosophila Genome-wide Obesity Screen Reveals Hedgehog as a Determinant of Brown versus White Adipose Cell Fate

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Adipogenesis at a glance

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Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells

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Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage

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Sonic Hedgehog Guides Axons through a Noncanonical, Src-Family-Kinase-Dependent Signaling Pathway

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Oxysterols are allosteric activators of the oncoprotein Smoothened

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Calorie Restriction: Is AMPK a Key Sensor and Effector

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Hedgehog signaling plays a conserved role in inhibiting fat formation

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Signaling by internalized G-protein-coupled receptors

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Activation of heterotrimeric G proteins by Smoothened

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Divergence of Hedgehog Signal Transduction Mechanism between Drosophila and Mammals

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Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

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Paracrine Hedgehog Signaling in Cancer

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G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling

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Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation

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Clinical Experience With Hedgehog Pathway Inhibitors

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Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord

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Heterotrimeric Gi Proteins Link Hedgehog Signaling to Activation of Rho Small GTPases to Promote Fibroblast Migration

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A Fluorescent Reporter of AMPK Activity and Cellular Energy Stress

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The Diabetic Phenotype Is Conserved in Myotubes Established From Diabetic Subjects

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Using brown adipose tissue to treat obesity – the central issue

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A highlight on Sonic hedgehog pathway

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