The DOI matches its Crossref record; 54 of the 55 references it cites were found in a registry or an index.
Embryonic Origin of Postnatal Neural Stem Cells
Open accessAbstract
Adult neural stem/progenitor (B1) cells within the walls of the lateral ventricles generate different types of neurons for the olfactory bulb (OB). The location of B1 cells determines the types of OB neurons they generate. Here we show that the majority of mouse B1 cell precursors are produced between embryonic days (E) 13.5 and 15.5 and remain largely quiescent until they become reactivated postnatally. Using a retroviral library carrying over 100,000 genetic tags, we found that B1 cells share a common progenitor with embryonic cells of the cortex, striatum, and septum, but this lineage relationship is lost before E15.5. The regional specification of B1 cells is evident as early as E11.5 and is spatially linked to the production of neurons that populate different areas of the forebrain. This study reveals an early embryonic regional specification of postnatal neural stem cells and the lineage relationship between them and embryonic progenitor cells.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Adult V-SVZ NSCs are set aside during embryogenesis, remaining largely quiescent until adulthood (Fuentealba et al., 2015; Furutachi et al., 2015), and reside in a complex microenvironment comprising diverse cell types and local and long-range signals (Silva-Vargas et al., 2013).”
From Single-Cell Analysis of Regional Differences in Adult V-SVZ Neural Stem Cell Lineages (2019) · cites this paper as Fuentealba et al., 2015
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898
Mechanisms and Functional Implications of Adult Neurogenesis
Zhao, C., Deng, W., & Gage, F. H. (2008) · Cell · doi:10.1016/j.cell.2008.01.033 · Cited by 3,007
Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions
Ming, G.-L., & Song, H. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.001 · Cited by 2,651
The Glial Nature of Embryonic and Adult Neural Stem Cells
Kriegstein, A., & Alvarez-Buylla, A. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135600 · Cited by 2,475
Long-Distance Neuronal Migration in the Adult Mammalian Brain
Lois, C., & Álvarez-Buylla, A. (1994) · Science · doi:10.1126/science.8178174 · Cited by 2,331
Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system
Livet, J., Weissman, T. A., Kang, H., Draft, R. W., Lu, J., Bennis, R. A., Sanes, J. R., & Lichtman, J. W. (2007) · Nature · doi:10.1038/nature06293 · Cited by 1,876
The development of neural stem cells
Temple, S. (2001) · Nature · doi:10.1038/35102174 · Cited by 1,479
Morshead, C. M., Reynolds, B. A., Craig, C. G., McBurney, M. W., Staines, W. A., Morassutti, D., Weiss, S., & van der Kooy, D. (1994) · Neuron · doi:10.1016/0896-6273(94)90046-9 · Cited by 1,403
Lineage Tracing Reveals Lgr5 + Stem Cell Activity in Mouse Intestinal Adenomas
Schepers, A. G., Snippert, H. J. G., Stange, D. E., van den Born, M., van Es, J. H., van de Wetering, M., & Clevers, H. C. (2012) · Science · doi:10.1126/science.1224676 · Cited by 1,110
A unified hypothesis on the lineage of neural stem cells
Álvarez-Buylla, A., García‐Verdugo, J. M., & Tramontin, A. D. (2001) · Nature reviews. Neuroscience · doi:10.1038/35067582 · Cited by 1,018
Flagged first, then by citations
1 of the 55 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 401–487 of 487
Cell biology of neuronal progenitor cells
Temple, S., Bai, Q., & Shen, Q. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-814405-3.00012-6 · Cited by 1
Investigating Autophagy Dysfunction Induced by a Parkinson's Disease-Causing Mutation in VPS35
Rahman, A. A. (2018) · ScholarWorks (Boise State University) · doi:10.18122/td/1488/boisestate · Cited by 1
Cascade Diversification Directs the Generation of Neuronal Diversity in HypothalamusPreprint
Wu, Q. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.17632/f72pdw59zr.1 · Cited by 1
Huang, H., Zhao, C., Hu, Q. N., Liu, Q., Sun, Y.-M., Chen, C., Huang, H., Zhou, C., & Wu, Y. (2021) · Research Square · doi:10.21203/rs.3.rs-178207/v1 · Cited by 1
Baur, K., Carrillo-García, C., Şan, Ş., von Hahn, M., Strelau, J., Hölzl-Wenig, G., Mandl, C., & Ciccolini, F. (2023) · bioRxiv · doi:10.1101/2022.12.02.518869 · Cited by 1
YAP/TAZ create a physical niche for the maintenance of adult neural stem cell quiescencePreprint
Blasco-Chamarro, L., García-Bolufer, P., Duart-Abadía, P., Jordán‐Pla, A., Sirerol-Piquer, M. S., Carrillo-Barberà, P., Sgattoni, C., Mateos-White, I., Gil, C., Morante‐Redolat, J. M., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.27.661955 · Cited by 1
“In order to evaluate physical interactions of quiescent NSCs specifically, we used in utero electroporation (IUE) to trace NSCs that enter quiescence at mid-gestation 55,56 .”
Coordinated neural progenitor adaptations drive primate neocortical downscalingPreprint
Tynianskaia, L., Betancourt, C. M. B., Grewe, E. M., Kniep, J. M., Liutikaite, N., Eşiyok, N., Heide, S., Rüger, N., Lindenwald, D. L., Drummer, C., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.19.706795 · Cited by 1
Adult neurogenesis: Is it showtime for clinical translation?
Lai, Y.-J., Sun, F., & Chen, G. (2015) · Genes & Diseases · doi:10.1016/j.gendis.2015.08.003
“A recent study by Alvarez-Buylla and colleagues revealed evidence indicating that adult NSCs were allocated and specified early in embryonic development.1 They also showed a lineage relationship between the embryonic and postnatal NSCs.1 It is known that two main regions continue to generate new neurons throughout adu…”
BackgroundInfluentialOrechio, D. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.10.2016.tde-29092016-112302
Lysophosphatidic Acid Signalling Enhances Glioma Stem Cell Properties
Ng, W. (2017) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-319-49343-5_9
Faiz, M., & Morshead, C. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804036-2.00005-4
The development and potential of spinal cord stem and progenitor cells
Li, X. (2018) · Figshare
Introduction to Adult Neurogenesis
Mobley, A. S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-811014-0.00005-6
All Roads Lead to Rome: Hippocampal Stem Cells Hop(x) the Continuous Way
Bai, Q., & Shen, Q. (2019) · Cell stem cell · doi:10.1016/j.stem.2019.04.013
Investigating the Effects of the Medulloblastoma Secretome on Neural Stem Cell Function
Simonetta, J. V. (2019) · TSpace (University of Toronto)
Neural Stem Cells and Their Niche
Reinhard, J., Roll, L., Theocharidis, U., & Faissner, A. (2020) · Learning materials in biosciences · doi:10.1007/978-3-030-33923-4_4
Derkach, D. (2019) · TSpace (University of Toronto)
Snyder, E. Y., Yip, S. S. F., Pernia, C. D., Lopez, C. A., Liu, Y., & Sajti, E. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-35214-7.00006-8 · Cited by 1
Genomic imprinting and neurodevelopment
Castillo, I. L. D., Lozano-Ureña, A., & Ferrón, S. R. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-817988-8.00005-1
Dause, T. J., Denninger, J. K., Smith, B. M., & Kirby, E. D. (2021)
Nguyen, T. D. (2016) · San José State University ScholarWorks (San Jose State University) · doi:10.31979/etd.v8xn-b84g
Mira, H., Díez del Corral, R., & Morales, A. V. (2020) · Frontiers research topics · doi:10.3389/978-2-88963-988-5
Pardal, R. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733939109.793552964
Cell of Origin as a Driver of Glioblastoma Subtype
Llaguno, S. R. A., & Parada, L. F. (2016) · Molecular & Cellular Oncology · doi:10.1080/23723556.2016.1145175
Nutrition influences nervous system development by regulating neural stem cell homeostasis
Das, P., Akanksha, V., & Arya, R. (2022) · Proceedings of the Indian National Science Academy · doi:10.1007/s43538-022-00107-z · Cited by 1
“Similarly, a fraction of mammalian SVZ NSCs also enters quiescence during embryonic neurogenesis, which later reactivates at the postnatal or adult stage (Fuentealba et al., 2015; Furutachi et al., 2013).”
BackgroundThe Autophagy Lysosomal Pathway: Friend or Foe in Adult Neural Stem Cells?
Calatayud-Baselga, I., & Mira, H. (2022) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-031-17362-2_8
Verma, R., Chen, X., Xin, D. E., Luo, Z., Ogurek, S., Xin, M., Rao, R., Berry, K., & Lu, Q. R. (2023) · doi:10.1158/0008-5472.c.6514394.v1
Verma, R., Chen, X., Xin, D. E., Luo, Z., Ogurek, S., Xin, M., Rao, R., Berry, K., & Lu, Q. R. (2023) · doi:10.1158/0008-5472.c.6514394
Sabet, S., & Breunig, J. J. (2023) · Developmental Neuroscience · doi:10.1159/000530329
“This barcoding technology has continued to be employed to answer critical questions such as the origins of neural stem cells and lineage potential [9, 58].”
Calatayud-Baselga, I., Casares-Crespo, L., Franch-Ibáñez, C., Guijarro-Nuez, J., Sanz, P., & Mira, H. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.03.539225
Generation of Projection Neuron Diversity in the Neocortex
Uzquiano, A., & Arlotta, P. (2023) · Wiley eBooks · doi:10.1002/9781119860914.ch11
Zaki, Z. M. M., Kuroda, A., Morimura, N., Hayashi, Y., & Hitoshi, S. (2023) · The Journal of Physiological Sciences · doi:10.1186/s12576-023-00876-2
“…introduced by a retrovirus or lentivirus in combination with a neural precursor cell-specific Cre-loxP system, lineages of individual NSCs have been analyzed to reveal that NSCs are regionally specified before embryonic day (E) 15.5 to supply neurons to different regions of the mouse brain [17].”
BackgroundInfluentialDevelopmental emergence of quiescent-like neural progenitor cells in the zebrafish embryonic brainPreprint
Liu, Y., Lembke, C., & Paridaen, J. T. M. L. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.13.580083
Embryonic diversification of adult neural stem cells and ependymal cellsPreprint
Yamaguchi, S., Kuniya, T., Omiya, H., Suzuki, Y., Seki, M., Ukai, H., Fang, L., Harada, Y., Kawaguchi, D., & Gotoh, Y. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.12.593751
Both intrinsic and microenvironmental factors contribute to the regulation of stem cell quiescence
Zhou, P., Hu, M., Li, Q., & Yang, G. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.31325
“Moreover, neural stem cells in the brain subventricular zone enter a dormant state at mid ‐ embryonic development (Fuentealba et al., 2015; Furutachi et al., 2015), which depends on p57 expression in the early stage (Furutachi et al., 2015).”
Zheng, J., Chen, Y., Hu, Y., Lin, J., Zhu, Y., Xu, M., Song, W., & Chen, X. X. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.16.599182
Paniagua‐Herranz, L., Serrano-López, J., Llorente-Sáez, C., Pérez-Sanz, M. L., de Agustín-Durán, D., Duart-Abadía, P., Domingo-Muelas, A., Vincelle-Nieto, Á., Bragado, P., Manzano-Franco, D., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1101/2024.11.29.626065
Linking Adult Olfactory Neurogenesis to Social Reproductive Stimuli: Mechanisms and Functions
Bovetti, S., Bonzano, S., Luzzati, F., Dati, C., Marchis, S. D., & Peretto, P. M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms26010163
Park, Y. M., & Kim, H. Y. (2025) · Developmental Neurobiology · doi:10.1002/dneu.22980
“The regional classification of these precursors is establishedduringembryonicdevelopment,andthefullplasticity of NSCs/NPCs is likely to be limited in a very short time (Fuentealba et al. 2015; O’Donoghue and Fisk 2004).”
Heterogeneity of the adult mammalian forebrain neurogenic ependyma: A comprehensive cellular map
Yang, X., Mu, Y., Wu, Q., Zhou, L., Fan, O. R., Lin, Q., Zhu, W., & Sun, Y. E. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-00789
“…dentate gyrus, which produces granule neurons, and the ependymal and subependymal zones lining the lateral ventricles, which continuously generate new neurons migrating along the rostral migratory stream to populate the olfactory bulb (Gage, 2000; Fuentealba et al., 2015; Obernier et al., 2018).”
Kempermann, G. (2025) · Oxford University Press eBooks · doi:10.1093/med/9780197519233.003.0003
Kempermann, G. (2025) · Oxford University Press eBooks · doi:10.1093/med/9780197519233.003.0004
The regenerative potential of adult Nestin+ cerebellar astroglia is limited compared to in neonatesPreprint
Bayin, N. S., Stephen, D. N., Koche, R. P., & Joyner, A. L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.01.691510
“…remains as to whether Nes+ Bg represent a subgroup of neonatal gliogenic NEPs that had expressed Hopx but did not undergo full differentiation to become S100 b +. Previous studies suggest that adult neural stem cells in the forebrain neurogenic niches are set aside during development 42,43 .”
Wu, X., Shen, Q., Zhang, Z., Zhang, D., Gu, Y., & Xing, D. (2021) · Figshare · doi:10.6084/m9.figshare.14773927
Zhang, Q., Yuan, G., Albizzati, E., Yang, J., Zhao, Z., Yu, X., Chang, X., Lee, C. H., Du, H., Lao, Z., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.27.696675
Developmental programming of hematopoietic stem cell dormancy by evasion of Notch signalingPreprint
Molinero, P. H., Cantón, E., Maqueda, M., Ruiz‐Herguido, C., Iglesias, A., González, J. R., Hadland, B., Espinosa, L., & Bigas, A. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.02.697352
“…the compatibility of quiescence within the developmental environment, also shown in other systems(Chakkalakal, Christensen et al. 2014, Fuentealba, Rompani et al. 2015) Notch signaling is essential for the emergence of HSCs from hemogenic endothelium in the AGM region(Kumano, Chiba et al. 2003,…”
InfluentialPhysiological effect of cytokines on adult neurogenesis: a focus on in vivo knock-out studies
Haidar, N., Salvon, L., Al-Sayyar, A., Kassem, O., Romano, A., & Rua, R. (2026) · Cells and Development · doi:10.1016/j.cdev.2026.204072
Shimizu, S., Ishino, Y., & Miyata, S. (2026) · Brain Research · doi:10.1016/j.brainres.2026.150268
Biswas, S. R., Tomsick, P. L., Pickrell, A. M., & Morton, P. D. (2026) · FEBS Letters · doi:10.1002/1873-3468.70335
“Postnatal neurogenesis is driven by a specialized subset of radial glial cells that diverge from the rapidly proliferating embryonic radial glia by mid-gestation, transitioning into a relatively quiescent state within adult neurogenic niches [46,47].”
Exploring Transcriptional Heterogeneity in the Postnatal SVZ
Zweifel, S. (2018) · theses.fr (ABES) · doi:10.70675/03ef449dz10baz4170z8ee3z0e9fe3c44a0f
Pellegrino, G. (2017) · theses.fr (ABES) · doi:10.70675/49c584f3z87f6z4320z924bz64015ded1e39
The role of Notch3 signaling in the maintenance of adult telencephalic neural stem cells
Than‐Trong, E. (2017) · theses.fr (ABES) · doi:10.70675/ebfd8b36zadd9z4798z8ae4ze3fa5c062a38
Rôle et connectivité des néo-neurones formés à l’âge adulte dans le bulbe olfactif
Grelat, A. (2018) · theses.fr (ABES) · doi:10.70675/c01c4ec0zba51z466aza2f1z09fdd6310b8f
Implication of DNA damage and repair in viability and differentiation of muscle stem cells
Sutcu, H. H. (2018) · theses.fr (ABES) · doi:10.70675/16d90ec5z5de0z495fzb8c9zc61a837a276b
Ghazale, H. (2019) · theses.fr (ABES) · doi:10.70675/131710fezef59z4eb9za19bz5e24cb31410d
“the positional identity of quiescent and activated NSCs (figure 13 and 19) [122], [159].”
BackgroundFeat-Vetel, J. (2018) · theses.fr (ABES) · doi:10.70675/11b7a40fzb10ez43b4z85aez38d4b27bbb07
Maurinot, F. (2019) · theses.fr (ABES) · doi:10.70675/f15d5957z45d3z4384zb0dbze345ee20e930
Álvarez, G. O. (2020) · theses.fr (ABES) · doi:10.70675/c245dc66z5428z4d00z9ce9z00ea191284cb
Characterization of cellular heterogeneity in Diffuse Low Grade Glioma
Augustus, M. (2020) · theses.fr (ABES) · doi:10.70675/037c23a4z44ddz4bb7z999ezb0c178c35170
TCF12 roles in oligodendroglial cells and gliomas
Archontidi, S. (2021) · theses.fr (ABES) · doi:10.70675/ff2d35a7z988ez4886zbc49z95515fc3af57
Control of ependymal cell differentiation by the mTOR signaling pathway
Srivastava, A. (2021) · theses.fr (ABES) · doi:10.70675/0e4dc286zfb40z4d2bza4cdzd6fdff1cc2e8
Unraveling the role of the lysosomal protein Prosaposin in neural stem cell quiescence
Labusch, M. (2022) · theses.fr (ABES) · doi:10.70675/87ff1a05z0defz40caza788z86260ae829ce
Régulation saisonnière de la plasticité cellulaire de l'hypothalamus mediobasal chez la brebis
Chevillard, P. (2022) · theses.fr (ABES) · doi:10.70675/6d5212ddzd1fcz4605z9e7az0c9212990874
Wells, A. M., Tanifuji, T., Takano, T., Endo, A., Kang, G., Esparza, M., Shi, Q., Bhat, M. A., & Hiroi, N. (2026) · Molecular Brain · doi:10.1186/s13041-026-01311-4
“…progenitor cells during the neonatal period give rise to oligodendrocyte precursor cells, oligodendrocytes, neural progenitor cells, and neurons [68–72], we sought to determine whether the effects of Tbx1 heterozygosity within the oligodendrocyte lineage induces behavioral and anatomical…”
InfluentialIsolation of postnatal human neural stem cellsPreprint
Liu, D. D., Eastman, A. E., Womack-Gambrel, N. L., Kim, C. N., He, J. Q., Raj, S., Reilly, E. E., Sinha, R., Uchida, N., Chau, K., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.11.731596
Cimino, D., Danese, A., Denoth‐Lippuner, A., Chlebik, P., Thorwirth, M., Simon, T., Richter, M. L., Jessberger, S., & Götz, M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.09.737275
“Here, aNSCs sustain neurogenesis for the olfactory bulb (OB) through the production of different interneuron subtypes (Fuentealba et al., 2015; Merkle et al., 2014).”
InfluentialAyobami, F. S., Udo, I. A., Odega, K., Omisakin, I. A., OLATUNDE, O. J., JIMMY, I. O., Afamefuna Cyril, E. G. B. O., Ajani, O. F., Osuji, B.-M. C., ONOKEVBAGBE, I. G., et al. (2026) · Discover Oncology · doi:10.1007/s12672-026-05652-3
Cebrián‐Silla, A., Dale-Huang, F., Redmond, S., Ortiz, C. E. A., Moriano, J., Nascimento, M. A., Li, Z., Guinto, C. D., González-Granero, S., Romero-Rodriguez, R., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.08.10.744053
Quiescence as an Active and Dynamic Regulator of Neural Stem Cells in Adult Olfactory Neurogenesis
Morante‐Redolat, J. M., & Fariñas, I. (2026) · European Journal of Neuroscience · doi:10.1111/ejn.70671
“For the V-SVZ, quiescence is first established during embryonic development, giving rise to the reservoir of adult NSCs that will remain largely dormant throughout life (Fuentealba et al. 2015; Furutachi et al. 2015).”
Coordinated neural progenitor adaptations contribute to primate neocortical downscaling
Tynianskaia, L., Betancourt, C. M. B., Grewe, E. M., Kniep, J., Liutikaite, N., Eşiyok, N., Göloğlu, İ. B., Heide, S., Rüger, N., Lindenwald, D. L., et al. (2026) · Science Advances · doi:10.1126/sciadv.aeg5563 · Cited by 1
“This heterogeneity has been described in other systems ( 60 – 64 ), where neural progenitors can reversibly enter quiescence or exhibit variable cell cycle dynamics.”
Spatiotemporal clonal architecture of the newborn mouse forebrain
Yuan, G., Kunst, M., Steyert, M. R., Keefe, M. G., Mathieu, R., van Velthoven, C. T. J., McMillen, D., Waters, J., Fukushima, Y., Kazerounian, A., et al. (2026) · Nature · doi:10.1038/s41586-026-11064-8
Kawase, K. (2026) · Pediatrics International · doi:10.1111/ped.70574
“After birth, RG acquire quiescence, thereby preventing the depletion of the postnatal NSC pool and enabling long-term postnatal neurogenesis [83, 84].”
Fauser, M., Bockholt, R., Keiner, S., Weselek, G., Hermann, A., Redecker, C., & Storch, A. (2026) · Neuroreport · doi:10.1097/wnr.0000000000002312
Metadata
- Authors
- Fuentealba, L. C., Rompani, S. B., Parraguez, J. I., Obernier, K., Romero, R., Cepko, C. L., & Alvarez-Buylla, A.
- Affiliations
- University of California, San Francisco (US)
- Howard Hughes Medical Institute (US)
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2015-06
- Volume
- 161
- Issue
- 7
- Pages
- 1644-1655
- ISSN
- 0092-8674 (ISSN-L)
- PMC
- PMC4475276
- OpenAlex
- W1617074755
- Cited by
- 488
- References
- 55
- Citations by year
- 2026: 22 · 2025: 38 · 2024: 29 · 2023: 43 · 2022: 43 · 2021: 51 · 2020: 62 · 2019: 58 · 2018: 45 · 2017: 47 · 2016: 35 · 2015: 15
- FWCI
- 19.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Howard Hughes Medical Institute
- Helen Hay Whitney Foundation
- Deutsche Forschungsgemeinschaft
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke (R37NS028478, NS-28478, R01NS028478)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD32116, R37HD032116, R01HD032116)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Keywords
- neural stem cells, neural progenitor cells, olfactory bulb, lateral ventricle, embryonic origin, regional specification, lineage tracing, quiescence, forebrain development, striatum, septum, cortex
- MeSH terms
- Animals, Embryo, Mammalian, Olfactory Bulb, Prosencephalon, Cell Lineage, Mice, Adult Stem Cells, Neural Stem Cells
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
