Microbiota-modulated metabolites shape the intestinal microenvironment by regulating NLRP6 inflammasome signaling

Levy, Maayan, Thaiss, Christoph A., Zeevi, David, Dohnalová, Lenka, Zilberman-Schapira, Gili, Mahdi, Jemal Ali, David, Eyal, Savidor, Alon +12 more·2015·Cell

DOI 10.1016/j.cell.2015.10.048

Cited by (964)

Items 101–200 of 964

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Levy, Maayan, Shapiro, Hagit, Thaiss, Christoph A., Elinav, Eran · 2017 · Trends in Immunology
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Yiting Yan, Lei Yu, Ying Qu, Zhen Fan, Ting Zhang, Yangbin Xu, Qian Du, Daniel Brügger, Yulin Chen, Ke Zhang et al. · 2023 · npj Biofilms and Microbiomes
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Drewes, Julia L, Housseau, Franck, Sears, Cynthia L · 2016 · British Journal of Cancer
The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function
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Niv Zmora, Maayan Levy, M. Pevsner-Fishcer, Eran Elinav · 2017 · Mucosal Immunology
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