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Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo
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“EMPs can still differentiate into cells of erythroid, megakaryocytic lineages, but also more readily produce different types of myeloid cells. 33 , 34”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [33]
In the citing paper
“This is followed by the production of erythro‐myeloid progenitors (EMPs) starting at E8.25. 32 , 33”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [33]
In the citing paper
“The presence of progenitors with mast cell potential in the YS and fetal liver was also later confirmed in more refined assays. 33”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [33]
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Citations
Cites
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175
Self-citationA clonogenic common myeloid progenitor that gives rise to all myeloid lineages
Akashi, K., Traver, D., Miyamoto, T., & Weissman, I. L. (2000) · Nature · doi:10.1038/35004599 · Cited by 2,617
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
Schulz, C., Perdiguero, E. G., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., et al. (2012) · Science · doi:10.1126/science.1219179 · Cited by 2,578
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
Orkin, S. H., & Zon, L. I. (2008) · Cell · doi:10.1016/j.cell.2008.01.025 · Cited by 2,570
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
Gomez Perdiguero, E., Klapproth, K., Schulz, C., Busch, K., Azzoni, E., Crozet, L., Garner, H., Trouillet, C., de Bruijn, M. F., Geissmann, F., et al. (2015) · Nature · doi:10.1038/nature13989 · Cited by 2,339 · cited 4×
“These definitive erythro-myeloid progenitors ("EMPs") are thought to be the source of the thousands of definitive erythroid progenitors and precursors found in the murine fetal liver prior to HSC colonization (Perdiguero et al., 2014; Frame et al., 2013 for review).”
BackgroundResultInfluentialMicroglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
Kierdorf, K., Erny, D., Goldmann, T., Sander, V., Schulz, C., Perdiguero, E. G., Wieghofer, P., Heinrich, A., Riemke, P., Hölscher, C., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3318 · Cited by 1,457
Hoeffel, G., Chen, J., Lavin, Y., Low, D., Almeida, F. F., See, P., Beaudin, A. E., Lum, J., Low, I., Forsberg, E. C., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.03.011 · Cited by 1,135 · cited 4×
“5 yolk sac prior to formation of the fetal liver (Tober et al. 2007; Perdiguero et al. 2014; Hoeffel et al. 2015).”
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Metadata
- Authors
- McGrath, K. E., Frame, J. M., Fegan, K. H., Bowen, J. R., Conway, S. J., Catherman, S. C., Kingsley, P. D., Koniski, A. D., & Palis, J.
- Venue
- Cell Reports
- Publisher
- Elsevier BV
- Published
- 2015-06
- Volume
- 11
- Issue
- 12
- Pages
- 1892-1904
- ISSN
- 2211-1247
- PMC
- PMC4490098
- Cited by
- 433
- References
- 8
- Language
- en
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