Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality

R: A Language and Environment for Statistical Computing

R Core Team (2000) · doi:10.32614/r.manuals · Cited by 355,706 · see citing works

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482 · see citing works

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Love, M. I., Huber, W., & Anders, S. (2014) · Genome Biology · doi:10.1186/s13059-014-0550-8 · Cited by 95,106 · see citing works

NIH Image to ImageJ: 25 years of image analysis

Schneider, C. A., Rasband, W. S., & Eliceiri, K. W. (2012) · Nature Methods · doi:10.1038/nmeth.2089 · Cited by 64,638 · see citing works

Cytoscape: A software Environment for integrated models of biomolecular interaction networks

Shannon, P., Markiel, A., Ozier, O., Baliga, N. S., Wang, J. T., Ramage, D., Amin, N., Schwikowski, B., & Ideker, T. (2003) · Genome Research · doi:10.1101/gr.1239303 · Cited by 51,888 · see citing works

STAR: ultrafast universal RNA-seq aligner

Dobin, A., Davis, C. A., Schlesinger, F., Drenkow, J., Zaleski, C., Jha, S., Batut, P., Chaisson, M., & Gingeras, T. R. (2013) · Bioinformatics · doi:10.1093/bioinformatics/bts635 · Cited by 51,709 · see citing works

limma powers differential expression analyses for RNA-sequencing and microarray studies

Ritchie, M. E., Phipson, B., Wu, D., Hu, Y., Law, C. W., Shi, W., & Smyth, G. K. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv007 · Cited by 40,458 · see citing works

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

Liao, Y., Smyth, G. K., & Shi, W. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btt656 · Cited by 27,219 · see citing works

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

Szklarczyk, D., Gable, A. L., Lyon, D., Junge, A., Wyder, S., Huerta-Cepas, J., Simonovic, M., Doncheva, N. T., Morris, J. H., Bork, P., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gky1131 · Cited by 17,749 · see citing works

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

Cox, J., & Mann, M. (2008) · Nature Biotechnology · doi:10.1038/nbt.1511 · Cited by 14,855 · see citing works

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

Edgar, R. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.1.207 · Cited by 13,288 · see citing works

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

Bolstad, B. M., Irizarry, R. A., Åstrand, M., & Speed, T. P. (2003) · Bioinformatics · doi:10.1093/bioinformatics/19.2.185 · Cited by 8,185 · see citing works

The PRIDE database and related tools and resources in 2019: improving support for quantification data

Pérez-Riverol, Y., Csordas, A., Bai, J.-W., Bernal-Llinares, M., Hewapathirana, S., Kundu, D. J., Inuganti, A., Griss, J., Mayer, G., Eisenacher, M., et al. (2018) · Nucleic Acids Res. · doi:10.1093/nar/gky1106 · Cited by 6,216 · see citing works

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

Cox, J., Neuhauser, N., Michalski, A., Scheltema, R. A., Olsen, J. V., & Mann, M. (2011) · Journal of Proteome Research · doi:10.1021/pr101065j · Cited by 5,350 · see citing works

Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

Elias, J. E., & Gygi, S. P. (2007) · Nature Methods · doi:10.1038/nmeth1019 · Cited by 3,925 · see citing works

WebGestalt 2019: gene set analysis toolkit with revamped UIs and APIs

Liao, Y., Wang, J., Jaehnig, E. J., Shi, Z., & Zhang, B. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz401 · Cited by 3,144 · see citing works

Fiber Types in Mammalian Skeletal Muscles

Schiaffino, S., & Reggiani, C. (2011) · Physiological Reviews · doi:10.1152/physrev.00031.2010 · Cited by 3,022 · see citing works

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

Brack, A. S., Conboy, M. J., Roy, S., Lee, M., Kuo, C. J., Keller, C., & Rando, T. A. (2007) · Science · doi:10.1126/science.1144090 · Cited by 1,564 · see citing works

Comprehensive Physiology

Candelotti, E., De Vito, P., De Luca, R., Gionfra, F., Percario, Z., Farías, R., Luly, P., Affabris, E., Davis, P., Pedersen, J., et al. (2010) · Wiley eBooks · doi:10.1002/cphy · Cited by 1,501 · see citing works

Autophagy maintains stemness by preventing senescence

García-Prat, L., Martínez-Vicente, M., Perdiguero, E., Ortet, L., Rodríguez-Ubreva, J., Rebollo, E., Ruiz-Bonilla, V., Gutarra, S., Ballestar, E., Serrano, A. L., et al. (2016) · Nature · doi:10.1038/nature16187 · Cited by 1,355 · see citing works

NAD ⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

Zhang, H., Ryu, D., Wu, Y., Gariani, K., Wang, X., Luan, P., D’Amico, D., Ropelle, E. R., Lutolf, M. P., Aebersold, R., et al. (2016) · Science · doi:10.1126/science.aaf2693 · Cited by 1,255 · see citing works

Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

Murphy, M. M., Lawson, J. A., Mathew, S. J., Hutcheson, D. A., & Kardon, G. (2011) · Development · doi:10.1242/dev.064162 · Cited by 1,249 · see citing works

Building Muscle: Molecular Regulation of MyogenesisPreprint

Bentzinger, C. F., Wang, Y. X., & Rudnicki, M. A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008342 · Cited by 1,198 · see citing works

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

Lepper, C., Partridge, T. A., & Fan, C.-M. (2011) · Development · doi:10.1242/dev.067595 · Cited by 1,105 · see citing works

Geriatric muscle stem cells switch reversible quiescence into senescence

Sousa-Victor, P., Gutarra, S., García-Prat, L., Rodriguez-Ubreva, J., Ortet, L., Ruiz-Bonilla, V., Jardí, M., Ballestar, E., González, S., Serrano, A. L., et al. (2014) · Nature · doi:10.1038/nature13013 · Cited by 1,010 · see citing works

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

Sambasivan, R., Yao, R., Kissenpfennig, A., Van Wittenberghe, L., Paldi, A., Gayraud-Morel, B., Guenou, H., Malissen, B., Tajbakhsh, S., & Galy, A. (2011) · Development · doi:10.1242/dev.067587 · Cited by 939 · see citing works

A draft network of ligand–receptor-mediated multicellular signalling in human

Ramilowski, J. A., Goldberg, T., Harshbarger, J., Kloppmann, E., Lizio, M., Satagopam, V. P., Itoh, M., Kawaji, H., Carninci, P., Rost, B., et al. (2015) · Nature Communications · doi:10.1038/ncomms8866 · Cited by 887 · see citing works

The aged niche disrupts muscle stem cell quiescence

Chakkalakal, J. V., Jones, K. M., Basson, M. A., & Brack, A. S. (2012) · Nature · doi:10.1038/nature11438 · Cited by 851 · see citing works

Satellite Cells and Skeletal Muscle Regeneration

Dumont, N. A., Bentzinger, C. F., Sincennes, M., & Rudnicki, M. A. (2015) · Comprehensive Physiology · doi:10.1002/cphy.c140068 · Cited by 719 · see citing works

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

Ryall, J. G., Dell’Orso, S., Derfoul, A., Juan, A., Zare, H., Feng, X., Clermont, D., Koulnis, M., Gutierrez-Cruz, G., Fulco, M., et al. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2014.12.004 · Cited by 575 · see citing works

Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging

Liu, L., Cheung, T. H., Charville, G. W., Hurgo, B. M. C., Leavitt, T., Shih, J., Brunet, A., & Rando, T. A. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.05.043 · Cited by 544 · see citing works

Inhibition of JAK-STAT signaling stimulates adult satellite cell function

Price, F. D., von Maltzahn, J., Bentzinger, C. F., Dumont, N. A., Yin, H., Chang, N. C., Wilson, D. H., Frenette, J., & Rudnicki, M. A. (2014) · Nature Medicine · doi:10.1038/nm.3655 · Cited by 433 · see citing works

Differentially Activated Macrophages Orchestrate Myogenic Precursor Cell Fate During Human Skeletal Muscle Regeneration

Saclier, M., Yacoub‐Youssef, H., Mackey, A. L., Arnold, L., Ardjoune, H., Magnan, M., Sailhan, F., Chelly, J., Pavlath, G. K., Mounier, R., et al. (2012) · Stem Cells · doi:10.1002/stem.1288 · Cited by 421 · see citing works

Accurate and Sensitive Peptide Identification with Mascot Percolator

Brosch, M., Yu, L., Hubbard, T., & Choudhary, J. S. (2009) · Journal of Proteome Research · doi:10.1021/pr800982s · Cited by 414 · see citing works

A unified approach to false discovery rate estimation

Strimmer, K. (2008) · BMC Bioinformatics · doi:10.1186/1471-2105-9-303 · Cited by 409 · see citing works

STAT3 signaling controls satellite cell expansion and skeletal muscle repair

Tierney, M. T., Aydogdu, T., Sala, D., Malecova, B., Gatto, S., Puri, P. L., Latella, L., & Sacco, A. (2014) · Nature Medicine · doi:10.1038/nm.3656 · Cited by 401 · see citing works

Cellular dynamics in the muscle satellite cell niche

Bentzinger, C. F., Wang, Y. X., Dumont, N. A., & Rudnicki, M. A. (2013) · The EMBO Reports · doi:10.1038/embor.2013.182 · Cited by 398 · see citing works

High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations

Giordani, L., He, G. J., Négroni, E., Sakai, H., Law, J. Y. C., Siu, M. M., Wan, R., Corneau, A., Tajbakhsh, S., Cheung, T. H., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.02.026 · Cited by 389 · see citing works

Fibronectin Regulates Wnt7a Signaling and Satellite Cell Expansion

Bentzinger, C. F., Wang, Y. X., von Maltzahn, J., Soleimani, V. D., Yin, H., & Rudnicki, M. A. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2012.09.015 · Cited by 386 · see citing works

Aging disrupts muscle stem cell function by impairing matricellular WISP1 secretion from fibro-adipogenic progenitors

Lukjanenko, L., Karaz, S., Stuelsatz, P., Gurriaran-Rodriguez, U., Michaud, J., Dammone, G., Sizzano, F., Mashinchian, O., Ancel, S., Migliavacca, E., et al. (2019) · Cell stem cell · doi:10.1016/j.stem.2018.12.014 · Cited by 374 · see citing works

A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration

Wosczyna, M. N., & Rando, T. A. (2018) · Developmental Cell · doi:10.1016/j.devcel.2018.06.018 · Cited by 353 · see citing works

Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice

Lukjanenko, L., Jung, M. J., Hegde, N., Perruisseau-Carrier, C., Migliavacca, E., Rozo, M., Karaz, S., Jacot, G. E., Schmidt, M., Li, L., et al. (2016) · Nature Medicine · doi:10.1038/nm.4126 · Cited by 337 · see citing works

Adult stem cells at work: regenerating skeletal muscle

Schmidt, M., Schüler, S. C., Hüttner, S. S., von Eyß, B., & von Maltzahn, J. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03093-6 · Cited by 313 · see citing works

Reciprocal signalling by Notch–Collagen V–CALCR retains muscle stem cells in their niche

Baghdadi, M. B., Castel, D., Machado, L., Fukada, S., Birk, D. E., Relaix, F., Tajbakhsh, S., & Mourikis, P. (2018) · Nature · doi:10.1038/s41586-018-0144-9 · Cited by 299 · see citing works

Cellular and epigenetic drivers of stem cell ageing

Ermolaeva, M., Neri, F., Ori, A., & Rudolph, K. L. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0020-3 · Cited by 272 · see citing works

Altered proteasome structure, function, and oxidation in aged muscle.

Ferrington, D. A., Husom, A. D., & Thompson, L. V. (2005) · The FASEB Journal · doi:10.1096/fj.04-2578fje · Cited by 259 · see citing works

Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal

Zismanov, V., Chichkov, V., Colangelo, V., Jamet, S., Wang, S., Syme, A., Koromilas, A. E., & Crist, C. G. (2015) · Cell stem cell · doi:10.1016/j.stem.2015.09.020 · Cited by 247 · see citing works

Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice

Rozo, M., Li, L., & Fan, C. (2016) · Nature Medicine · doi:10.1038/nm.4116 · Cited by 244 · see citing works

Age-Dependent Declines in Proteasome Activity in the Heart

Bulteau, A., Szweda, L. I., & Friguet, B. (2002) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2001.2663 · Cited by 237 · see citing works

Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

Kelmer Sacramento, E., Kirkpatrick, J. M., Mazzetto, M., Baumgart, M., Bartolome, A., Di Sanzo, S., Caterino, C., Sanguanini, M., Papaevgeniou, N., Lefaki, M., et al. (2020) · Molecular Systems Biology · doi:10.15252/msb.20209596 · Cited by 236 · see citing works

Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal

Rayagiri, S. S., Ranaldi, D., Raven, A., Mohamad Azhar, N. I. F., Lefebvre, O., Zammit, P. S., & Borycki, A.-G. (2018) · Nature Communications · doi:10.1038/s41467-018-03425-3 · Cited by 218 · see citing works

Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats

Ori, A., Toyama, B. H., Harris, M. S., Bock, T., Iskar, M., Bork, P., Ingolia, N. T., Hetzer, M. W., & Beck, M. (2015) · Cell Systems · doi:10.1016/j.cels.2015.08.012 · Cited by 201 · see citing works

Cellular and Molecular Mechanisms Regulating Fibrosis in Skeletal Muscle Repair and Disease

Serrano, A. L., Mann, C. J., Vidal, B., Ardite, E., Perdiguero, E., & Muñoz-Cánoves, P. (2011) · Current Topics in Developmental Biology · doi:10.1016/b978-0-12-385940-2.00007-3 · Cited by 200 · see citing works

Scaffolding Protein Grb2-associated Binder 1 Sustains Epidermal Growth Factor-induced Mitogenic and Survival Signaling by Multiple Positive Feedback Loops

Kiyatkin, A., Aksamitiene, E., Markevich, N. I., Borisov, N. M., Hoek, J. B., & Kholodenko, B. N. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600482200 · Cited by 195 · see citing works

Protein biogenesis machinery is a driver of replicative aging in yeast

Janssens, G. E., Meinema, A. C., González, J., Wolters, J. C., Schmidt, A., Guryev, V., Bischoff, R., Wit, E. C., Veenhoff, L. M., & Heinemann, M. (2015) · eLife · doi:10.7554/elife.08527 · Cited by 193 · see citing works

Satellite Cells

Chang, N. C., & Rudnicki, M. A. (2014) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-416022-4.00006-8 · Cited by 180 · see citing works

The ins and outs of muscle stem cell aging

Brack, A. S., & Muñoz-Cánoves, P. (2015) · Skeletal Muscle · doi:10.1186/s13395-016-0072-z · Cited by 166 · see citing works

Muscle stem cell aging: regulation and rejuvenation

Sousa-Victor, P., García-Prat, L., Serrano, A. L., Perdiguero, E., & Muñoz-Cánoves, P. (2015) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2015.03.006 · Cited by 163 · see citing works

FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age

García-Prat, L., Perdiguero, E., Alonso-Martín, S., Dell’Orso, S., Ravichandran, S., Brooks, S. R., Juan, A. H., Campanario, S., Jiang, K., Hong, X., et al. (2020) · Nature Cell Biology · doi:10.1038/s41556-020-00593-7 · Cited by 161 · see citing works

Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions

Courcelles, M., Frémin, C., Voisin, L., Lemieux, S., Meloche, S., & Thibault, P. (2013) · Molecular Systems Biology · doi:10.1038/msb.2013.25 · Cited by 158 · see citing works

Increased Stiffness in Aged Skeletal Muscle Impairs Muscle Progenitor Cell Proliferative Activity

Lacraz, G., Rouleau, A.-J., Couture, V., Söllrald, T., Drouin, G., Veillette, N., Grandbois, M., & Grenier, G. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136217 · Cited by 156 · see citing works

Robust, Sensitive, and Automated Phosphopeptide Enrichment Optimized for Low Sample Amounts Applied to Primary Hippocampal Neurons

Post, H., Penning, R., Fitzpatrick, M. A., Garrigues, L., Wu, W., MacGillavry, H. D., Hoogenraad, C. C., Heck, A. J. R., & Altelaar, M. A. F. (2016) · Journal of Proteome Research · doi:10.1021/acs.jproteome.6b00753 · Cited by 144 · see citing works

A comprehensive transcriptome signature of murine hematopoietic stem cell aging

Flohr Svendsen, A., Yang, D., Kim, K., Lazare, S., Skinder, N., Zwart, E., Mura-Meszaros, A., Ausema, A., von Eyss, B., de Haan, G., et al. (2021) · Blood · doi:10.1182/blood.2020009729 · Cited by 138 · see citing works

Skeletal muscle stem cells in comfort and stress

Evano, B., & Tajbakhsh, S. (2018) · npj Regenerative Medicine · doi:10.1038/s41536-018-0062-3 · Cited by 132 · see citing works

The Muscle Stem Cell Niche in Health and Disease

Mashinchian, O., Pisconti, A., Moal, E. L., & Bentzinger, C. F. (2017) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2017.08.003 · Cited by 127 · see citing works

The Novel SPARC Family Member SMOC-2 Potentiates Angiogenic Growth Factor Activity

Rocnik, E. F., Liu, P., Sato, K., Walsh, K., & Vaziri, C. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m513463200 · Cited by 121 · see citing works

Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging

Wei, Y.-N., Hu, H.-Y., Xie, G.-C., Fu, N., Ning, Z.-B., Zeng, R., & Khaitovich, P. (2015) · Genome Biology · doi:10.1186/s13059-015-0608-2 · Cited by 117 · see citing works

Isolation of Muscle Stem Cells by Fluorescence Activated Cell Sorting Cytometry

Pasut, A., Oleynik, P., & Rudnicki, M. A. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-343-1_3 · Cited by 111 · see citing works

An age‐related type IIB to IIX myosin heavy chain switching in rat skeletal muscle

Larsson, L., Biral, D., Campione, M., & Schiaffino, S. (1993) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1993.tb09493.x · Cited by 105 · see citing works

WISP1: Clinical Insights for a Proliferative and Restorative Member of the CCN Family

Maiese, K. (2014) · Current Neurovascular Research · doi:10.2174/1567202611666140912115107 · Cited by 103 · see citing works

The origins and non-canonical functions of macrophages in development and regeneration

Théret, M., Mounier, R., & Rossi, F. M. V. (2019) · Development · doi:10.1242/dev.156000 · Cited by 85 · see citing works

CCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα

Ono, M., Masaki, A., Maeda, A., Kilts, T. M., Hara, E. S., Komori, T., Pham, H. T., Kuboki, T., & Young, M. F. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.01.004 · Cited by 78 · see citing works

The Ubiquitin-Proteasome System Is Indispensable for the Maintenance of Muscle Stem Cells

Kitajima, Y., Suzuki, N., Nunomiya, A., Osana, S., Yoshioka, K., Tashiro, Y., Takahashi, R., Ono, Y., Aoki, M., & Nagatomi, R. (2018) · Stem Cell Reports · doi:10.1016/j.stemcr.2018.10.009 · Cited by 75 · see citing works

The SPARC-related Factor SMOC-2 Promotes Growth Factor-induced Cyclin D1 Expression and DNA Synthesis via Integrin-linked Kinase

Liu, P., Lü, J., Cardoso, W. V., & Vaziri, C. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-05-0510 · Cited by 69 · see citing works

Three-dimensional scaffolds of fetal decellularized hearts exhibit enhanced potential to support cardiac cells in comparison to the adult

Silva, A. C., Rodrigues, S. C., Caldeira, J., Nunes, A. M., Sampaio‐Pinto, V., Resende, T. P., Oliveira, M. J., Barbosa, M. A., Þorsteinsdóttir, S., Nascimento, D. S., et al. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.06.062 · Cited by 67 · see citing works

Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging

Heinze, I., Bens, M., Calzia, E., Holtze, S., Dakhovnik, O., Sahm, A., Kirkpatrick, J. M., Szafranski, K., Romanov, N., Sama, S. N., et al. (2018) · BMC Biology · doi:10.1186/s12915-018-0547-y · Cited by 65 · see citing works

Gene Expression Profiling of Muscle Stem Cells Identifies Novel Regulators of Postnatal Myogenesis

Alonso‐Martín, S., Rochat, A., Mademtzoglou, D., Morais, J., de Reyniès, A., Aurade, F., Chang, T. H., Zammit, P. S., & Relaix, F. (2016) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2016.00058 · Cited by 61 · see citing works

A Single Cell Transcriptomic Atlas Characterizes Aging Tissues in the MousePreprint

Pisco, A. O., McGeever, A., Schaum, N., Karkanias, J., Neff, N. F., Darmanis, S., Wyss‐Coray, T., & Quake, S. R. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/661728 · Cited by 56 · see citing works

enhancedGraphics: a Cytoscape app for enhanced node graphics

Morris, J. H., Kuchinsky, A., Ferrin, T. E., & Pico, A. R. (2014) · F1000Research · doi:10.12688/f1000research.4460.1 · Cited by 40 · see citing works

Muscle stem cell renewal suppressed by GAS1 can be reversed by GDNF in mice

Li, L., Rozo, M., Yue, S., Zheng, X., Tan, F. J., Lepper, C., & Fan, C. (2019) · Nature Metabolism · doi:10.1038/s42255-019-0110-3 · Cited by 40 · see citing works

Testosterone exerts antiapoptotic effects against H2O2 in C2C12 skeletal muscle cells through the apoptotic intrinsic pathway

Pronsato, L., Boland, R., & Milanesi, L. M. (2012) · Journal of Endocrinology · doi:10.1530/joe-11-0234 · Cited by 39 · see citing works

Smoc2 potentiates proliferation of hepatocellular carcinoma cells via promotion of cell cycle progression

Su, J., Kuai, J., & Li, Y. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i45.10053 · Cited by 35 · see citing works

Isolation and Culture of Individual Myofibers and Their Adjacent Muscle Stem Cells from Aged and Adult Skeletal Muscle

Hüttner, S. S., Ahrens, H. E., Schmidt, M., Henze, H., Jung, M. J., Schüler, S. C., & von Maltzahn, J. (2019) · Methods in molecular biology · doi:10.1007/7651_2019_209 · Cited by 24 · see citing works

Extrinsic Regulation of Satellite Cell Function and Muscle Regeneration Capacity during Aging

Chakkalakal, J. V. (2012) · Journal of Stem Cell Research & Therapy · doi:10.4172/2157-7633.s11-001 · Cited by 23 · see citing works

Systemic Perturbation of the ERK Signaling Pathway by the Proteasome Inhibitor, MG132

Cirit, M., Grant, K., & Haugh, J. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050975 · Cited by 19 · see citing works

Stem cell aging: The upcoming era of proteins and metabolites

Schüler, S. C., Gebert, N., & Ori‬‬, A. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111288 · Cited by 18 · see citing works

Quantifying compartment‐associated variations of protein abundance in proteomics data

Parca, L., Beck, M., Peer Bork, B., & Ori‬‬, A. (2018) · Molecular Systems Biology · doi:10.15252/msb.20178131 · Cited by 17 · see citing works

Fast searches of large collections of single-cell data using scfind

Lee, J. T. H., Patikas, N., Kiselev, V. Y., & Hemberg, M. (2021) · Nature Methods · doi:10.1038/s41592-021-01076-9 · Cited by 17 · see citing works

Recovery of skeletal muscle function following injury is not augmented by acute resveratrol supplementation

Rogers, R. G., Baumann, C., & Otis, J. S. (2015) · International Journal of Clinical and Experimental Physiology · doi:10.4103/2348-8093.155515 · Cited by 12 · see citing works

Control of satellite cell function in muscle regeneration and its disruption in ageing

Sousa-Victor, P., García-Prat, L., & Muñoz-Cánoves, P. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-021-00421-2 · Cited by 476 · see citing works

Ageing and rejuvenation of tissue stem cells and their niches

Brunet, A., Goodell, M. A., & Rando, T. A. (2023) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00510-w · Cited by 407 · see citing works

Biomarkers of aging

Bao, H., Cao, J., Chen, M., Min, C., Chen, W., Chen, X., Chen, Y., Chen, Y., Chen, Y., Chen, Z., et al. (2023) · Science China Life Sciences · doi:10.1007/s11427-023-2305-0 · Cited by 389 · see citing works

Circulating tumor cells: from new biological insights to clinical practice

Gu, X., Wei, S., & Lv, X. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01938-6 · Cited by 195 · see citing works

Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases

Ji, S., Xiong, M., Chen, H., Liu, Y., Zhou, L., Hong, Y., Wang, M., Wang, C., Fu, X., & Sun, X. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01343-5 · Cited by 166 · see citing works

Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging

Liu, L. A., Kim, S., Buckley, M. T., Reyes, J. M., Kang, J., Tian, L., Wang, M., Lieu, A. C., Mao, M., Rodríguez-Mateo, C., et al. (2023) · Cell stem cell · doi:10.1016/j.stem.2023.03.016 · Cited by 110 · see citing works

Extracellular Matrix Dynamics as an Emerging yet Understudied Hallmark of Aging and Longevity

Statzer, C., Park, J. Y. C., & Ewald, C. (2023) · Aging and Disease · doi:10.14336/ad.2022.1116 · Cited by 75 · see citing works

Fiber-Type Shifting in Sarcopenia of Old Age: Proteomic Profiling of the Contractile Apparatus of Skeletal Muscles

Dowling, P., Gargan, S., Swandulla, D., & Ohlendieck, K. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032415 · Cited by 95 · see citing works

Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche

Schüler, S. C., Liu, Y., Dumontier, S., Grandbois, M., Moal, E. L., Cornelison, D., & Bentzinger, C. F. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1056523 · Cited by 82 · see citing works

Disuse‐induced muscle fibrosis, cellular senescence, and senescence‐associated secretory phenotype in older adults are alleviated during re‐ambulation with metformin pre‐treatment

Petrocelli, J. J., McKenzie, A. I., de Hart, N. M. M. P., Reidy, P. T., Mahmassani, Z. S., Keeble, A. R., Kaput, K. L., Wahl, M., Rondina, M. T., Marcus, R. L., et al. (2023) · Aging Cell · doi:10.1111/acel.13936 · Cited by 71 · see citing works

Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations

Leinroth, A. P., Mirando, A. J., Rouse, D. C., Kobayahsi, Y., Tata, P. R., Rueckert, H. E., Liao, Y., Long, J. T., Chakkalakal, J. V., & Hilton, M. J. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110785 · Cited by 69 · see citing works

Ageing induces tissue‐specific transcriptomic changes in Caenorhabditis elegans

Wang, X., Jiang, Q., Song, Y., He, Z., Zhang, H., Song, M., Zhang, X., Dai, Y., Karalay, O., Dieterich, C., et al. (2022) · The EMBO Journal · doi:10.15252/embj.2021109633 · Cited by 59 · see citing works

Mechanisms of muscle cells alterations and regeneration decline during aging

Chinvattanachot, G., Rivas, D., & Duque, G. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102589 · Cited by 58 · see citing works

A glitch in the matrix: the pivotal role for extracellular matrix remodeling during muscle hypertrophy

Brightwell, C. R., Latham, C. M., Thomas, N. T., Keeble, A. R., Murach, K. A., & Fry, C. S. (2022) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00200.2022 · Cited by 52 · see citing works

Regulation of Satellite Cells Functions during Skeletal Muscle Regeneration: A Critical Step in Physiological and Pathological Conditions

Careccia, G., Mangiavini, L., & Cirillo, F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010512 · Cited by 59 · see citing works

Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans

Teuscher, A. C., Statzer, C., Goyala, A., Domenig, S. A., Schoen, I., Hess, M., Hofer, A. M., Fossati, A., Viola Vogel, B., Göksel, O., et al. (2024) · Nature Communications · doi:10.1038/s41467-023-44409-2 · Cited by 51 · see citing works

Cellular reprogramming as a tool to model human aging in a dish

Pitrez, P. R., Monteiro, L. M., Borgogno, O., Nissan, X., Mertens, J., & Ferreira, L. (2024) · Nature Communications · doi:10.1038/s41467-024-46004-5 · Cited by 49 · see citing works

The meaning of adaptation in aging: insights from cellular senescence, epigenetic clocks and stem cell alterations

Ogrodnik, M. B., & Gladyshev, V. N. (2023) · Nature Aging · doi:10.1038/s43587-023-00447-5 · Cited by 46 · see citing works

Perfusable adipose decellularized extracellular matrix biological scaffold co-recellularized with adipose-derived stem cells and L6 promotes functional skeletal muscle regeneration following volumetric muscle loss

Liang, W., Han, M., Guan, L., Dang, W., Wu, H., Meng, X., Zhen, Y., Lin, W., Ao, R., Hu, X., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122529 · Cited by 47 · see citing works

Macrophage Involvement in Aging-Associated Skeletal Muscle Regeneration

Cui, C., Ferrucci, L., & Gorospe, M. (2023) · Cells · doi:10.3390/cells12091214 · Cited by 47 · see citing works

A bioprinted complex tissue model for myotendinous junction with biochemical and biophysical cues

Kim, W. J., & Kim, G. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10321 · Cited by 40 · see citing works

Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength

Wang, Y. X., Palla, A. R., Ho, A. T. V., Robinson, D. C. L., Ravichandran, M., Markov, G. J., Mai, T., Still, C., Balsubramani, A., Nair, S., et al. (2025) · Cell stem cell · doi:10.1016/j.stem.2025.05.012 · Cited by 34 · see citing works

Inflammatory, mitochondrial, and senescence-related markers: Underlying biological pathways of muscle aging and new therapeutic targets

Picca, A., Lozanoska‐Ochser, B., Calvani, R., Coelho‐Júnior, H. J., Leewenburgh, C., & Marzetti, E. (2023) · Experimental Gerontology · doi:10.1016/j.exger.2023.112204 · Cited by 30 · see citing works

Identification of porcine adipose progenitor cells by fluorescence-activated cell sorting for the preparation of cultured fat by 3D bioprinting

Song, W., Liu, P., Meng, Z.-Q., Zheng, Y., Zhou, G., Li, H.-X., & Ding, S.-J. (2022) · Food Research International · doi:10.1016/j.foodres.2022.111952 · Cited by 30 · see citing works

Remodeling of the Cardiac Extracellular Matrix Proteome During Chronological and Pathological Aging

Santinha, D. R., Vilaça, A., Estronca, L. M. B. B., Schüler, S. C., Bartoli, C., Sandre‐Giovannoli, A. D., Figueiredo, A., Quaas, M., Pompe, W., Ori‬‬, A., et al. (2023) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2023.100706 · Cited by 29 · see citing works

A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in agingPreprint

Wang, Y. X., Holbrook, C. A., Hamilton, J. N., Garoussian, J., Afshar, M., Su, S., Schürch, C. M., Lee, M. Y., Goltsev, Y., Kundaje, A. B., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.06.10.494732 · Cited by 29 · see citing works

Denervation alters the secretome of myofibers and thereby affects muscle stem cell lineage progression and functionality

Henze, H., Hüttner, S. S., Koch, P., Schüler, S. C., Groth, M., von Eyß, B., & von Maltzahn, J. (2024) · npj Regenerative Medicine · doi:10.1038/s41536-024-00353-3 · Cited by 28 · see citing works

Strain-dependent dynamic re-alignment of collagen fibers in skeletal muscle extracellular matrix

Wohlgemuth, R. P., Sriram, S., Henricson, K. E., Dinh, D. T., Brashear, S. E., & Smith, L. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.08.035 · Cited by 23 · see citing works

Reduced growth rate of aged muscle stem cells is associated with impaired mechanosensitivity

Haroon, M. F., Boers, H. E., Bakker, A. D., Bloks, N. G. C., Hoogaars, W. M. H., Giordani, L., Musters, R. J. P., Deldicque, L., Koppo, K., Grand, F. L., et al. (2022) · Aging · doi:10.18632/aging.203830 · Cited by 21 · see citing works

Deficiency of skeletal muscle Agrin contributes to the pathogenesis of age-related sarcopenia in mice

Chen, J., Chen, H., Dong, X., Hui, T., Yan, M., Ren, D., Zou, S., Wang, S., Fei, E., Zhang, W., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06581-1 · Cited by 22 · see citing works

Immune aging impairs muscle regeneration via macrophage-derived anti-oxidant selenoprotein P

Hoang, D.-H., Bouvière, J., Galvis, J., Moullé, P., Mercier, O., Migliavacca, E., Ghosh, A., Juban, G., Liot, S., Stuelsatz, P., et al. (2025) · EMBO Reports · doi:10.1038/s44319-025-00516-3 · Cited by 20 · see citing works

Exercise Promotes Tissue Regeneration: Mechanisms Involved and Therapeutic Scope

Liu, C., Wu, X., Vulugundam, G., Gokulnath, P., Li, G., & Xiao, J. (2023) · Sports Medicine - Open · doi:10.1186/s40798-023-00573-9 · Cited by 20 · see citing works

Considerations for reproducible omics in aging research

Singh, P. P., & Benayoun, B. A. (2023) · Nature Aging · doi:10.1038/s43587-023-00448-4 · Cited by 18 · see citing works

Stellate cell expression of SPARC-related modular calcium-binding protein 2 is associated with human non-alcoholic fatty liver disease severity

Larsen, F. T., Hansen, D., Terkelsen, M. K., Bendixen, S. M., Avolio, F., Wernberg, C. W., Lauridsen, M. M., Grønkjær, L. L., Jacobsen, B. G., Gammelmark, E., et al. (2022) · JHEP Reports · doi:10.1016/j.jhepr.2022.100615 · Cited by 17 · see citing works

Myofibers Cultured in Viscoelastic Hydrogels Reveal the Effects of Integrin-Binding and Mechanosensing on Muscle Satellite Cells

Chang, T.-L., Borelli, A. N., Cutler, A. A., Olwin, B. B., & Anseth, K. S. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.11.044 · Cited by 15 · see citing works

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

Devrukhkar, P. R., Watson, M. A., Soygur, B., Wu, F., Bons, J., Anvari, H., Atazhanova, T., Martin, N., Tran, T., Schneider, K., et al. (2025) · Aging Cell · doi:10.1111/acel.70111 · Cited by 15 · see citing works

Proteomics approach identifies aqueous humor biomarkers in retinal diseases

Huang, K., Schofield, C., Nguy, T., Dere, R. C., Wolowski, V., Siebourg‐Polster, J., Dieckmann, A., Garweg, J. G., Chang, M., Honigberg, L. A., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-00862-2 · Cited by 14 · see citing works

Mechanotherapy Reprograms Aged Muscle Stromal Cells to Remodel the Extracellular Matrix during Recovery from Disuse

Hettinger, Z. R., Wen, Y., Peck, B. D., Hamagata, K., Confides, A. L., Pelt, D. V. V., Harrison, D., Miller, B. F., Butterfield, T. A., & Dupont-Versteegden, E. (2022) · Function · doi:10.1093/function/zqac015 · Cited by 13 · see citing works

Epigenetic control of muscle stem cells: time for a new dimension

Bianconi, V., & Mozzetta, C. (2022) · Trends in Genetics · doi:10.1016/j.tig.2022.01.001 · Cited by 13 · see citing works

Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues

Reed, E., Fellows, A., Lu, R., Rienks, M., Schmidt, L. E., Yin, X., Duregotti, E., Brandt, M., Krasemann, S., Hartmann, K., et al. (2022) · Matrix Biology Plus · doi:10.1016/j.mbplus.2022.100122 · Cited by 13 · see citing works

Reconstructing the ageing extracellular matrix

Schnellmann, R., & Gerecht, S. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-023-00049-1 · Cited by 13 · see citing works

Skeletal muscle proteomics: considerations and opportunities

Wong, J. P. H., Ng, Y., Larsen, J. K., Blazev, R., Deshmukh, A. S., & Parker, B. L. (2025) · npj Metabolic Health and Disease · doi:10.1038/s44324-025-00073-2 · Cited by 15 · see citing works

Nicotinamide and Pyridoxine in Muscle Aging: Nutritional Regulation of Redox, Inflammation, and Regeneration

Nowacka, A., Śniegocki, M., Śniegocka, M., & Ziółkowska, E. (2025) · Antioxidants · doi:10.3390/antiox14080911 · Cited by 11 · see citing works

Cellular survivorship bias as a mechanistic driver of muscle stem cell aging

Kang, J., Benjamin, D. I., Guo, Q., Evangelista, C., Kim, S., Arjona, M., Both, P., Chung, M., Krishnan, A. K., Dhaliwal, G., et al. (2026) · Science · doi:10.1126/science.ads9175 · Cited by 11 · see citing works

CCN2 participates in overload-induced skeletal muscle hypertrophy

Petrosino, J. M., Longenecker, J. Z., Angell, C. D., Hinger, S. A., Martens, C. R., & Accornero, F. (2022) · Matrix Biology · doi:10.1016/j.matbio.2022.01.003 · Cited by 11 · see citing works

Organelle dysfunction and its contribution to metabolic impairments in aging and age-related diseases

Heiby, J. C., & Ori‬‬, A. (2022) · Current Opinion in Systems Biology · doi:10.1016/j.coisb.2022.100416 · Cited by 11 · see citing works

Glycation‐mediated tissue‐level remodeling of brain meningeal membrane by aging

Kim, H. M., Kim, S., Sim, J., Ma, B. S., Yong, I., Jo, Y., Kim, T., Chang, J., Park, S., Jeong, Y., et al. (2023) · Aging Cell · doi:10.1111/acel.13805 · Cited by 10 · see citing works

Age‐related nitration/dysfunction of myogenic stem cell activator HGF

Elgaabari, A., Imatomi, N., Kido, H., Nakashima, T., Okuda, S., Manabe, Y., Sawano, S., Mizunoya, W., Kaneko, R., Tanaka, S., et al. (2023) · Aging Cell · doi:10.1111/acel.14041 · Cited by 9 · see citing works

Notch1 and Notch2 Signaling Exclusively but Cooperatively Maintain Fetal Myogenic Progenitors

Jo, Y., Park, I., Yoo, K., Woo, H.-Y., Kim, Y. L., Kim, Y.-E., Kim, J.-H., & Kong, Y. (2022) · Stem Cells · doi:10.1093/stmcls/sxac056 · Cited by 9 · see citing works

Loss of transcriptional heterogeneity in aged human muscle stem cells

Barruet, E., Striedinger, K., Marangoni, P., & Pomerantz, J. H. (2023) · PLoS ONE · doi:10.1371/journal.pone.0285018 · Cited by 8 · see citing works

Tracking of Nascent Matrix Deposition during Muscle Stem Cell Activation across Lifespan Using Engineered Hydrogels

Duran, P., Yang, B. A., Plaster, E. M., Eiken, M. K., Loebel, C., & Aguilar, C. A. (2024) · Advanced Biology · doi:10.1002/adbi.202400091 · Cited by 8 · see citing works

Identifying Cell‐Type‐Specific Metabolic Signatures Using Transcriptome and Proteome Analyses

Gebert, N., Rahman, S., Lewis, C. A., Ori‬‬, A., & Cheng, C. (2021) · Current Protocols · doi:10.1002/cpz1.245 · Cited by 7 · see citing works

Tissue‐specific functions of MSCs are linked to homeostatic muscle maintenance and alter with aging

Kurosawa, T., Ikemoto‐Uezumi, M., Yoshimoto, Y., Minato, K., Kaji, N., Chaen, T., Hase, E., Minamikawa, T., Yasui, T., Horiguchi, K., et al. (2024) · Aging Cell · doi:10.1111/acel.14299 · Cited by 7 · see citing works

Overcoming muscle stem cell aging

Memczak, S., & Belmonte, J. C. I. (2023) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2023.102127 · Cited by 7 · see citing works

Expression of intramuscular extracellular matrix proteins in vastus lateralis muscle fibres between atrophic and non-atrophic COPD

Kritikaki, E., Terzis, G. D., Soundararajan, M., Vogiatzis, I., & Simoes, D. C. M. (2024) · ERJ Open Research · doi:10.1183/23120541.00857-2023 · Cited by 7 · see citing works

Matricellular Protein SMOC2 Potentiates BMP9-Induced Osteogenic Differentiation in Mesenchymal Stem Cells through the Enhancement of FAK/PI3K/AKT Signaling

He, W.-G., Deng, Y., Ke, K.-X., Cao, X.-L., Liu, S., Yang, Y., Luo, H., Yao, X., Gao, X. Y., Du, Y., et al. (2023) · Stem Cells International · doi:10.1155/2023/5915988 · Cited by 7 · see citing works

Aging impairs skeletal muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution via fibro-adipogenic progenitorsPreprint

García‐Carrizo, F., Gohlke, S., Lenihan-Geels, G. N., Jank, A., Leer, M., Soultoukis, G. A., Oveisi, M., Herpich, C., Garrido, C. A., Kotsaris, G., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.27.568776 · Cited by 6 · see citing works

Decorin Deficiency Promotes D‐Galactose–Induced Skeletal Muscle Atrophy and Fibrosis by Regulating ITGB1/Akt/mTOR Signalling Pathway

Luo, X., Zhang, M., Chen, L.-L., Wang, R., Lian, J., Yang, Z., Iozzo, R. V., Wang, J., Zhang, Y., & Bi, X. (2025) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.70144 · Cited by 6 · see citing works

Mechanistic insights into stem cell aging: Pathways and processes

Fauzi, A., Wong, C. Z. E., Tee, P. Y. E., Yau, A. W. N., Rashid, E. A., Tang, Y. Q., & Chia, A. Y. Y. (2026) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2026.112160 · Cited by 5 · see citing works

Pdgfrα+ stromal cells, a key regulator for tissue homeostasis and dysfunction in distinct organs

Kang, X., Zhao, K., Huang, Z., Fukada, S., Qi, X., & Miao, H. (2024) · Genes & Diseases · doi:10.1016/j.gendis.2024.101264 · Cited by 5 · see citing works

Treating age‐related loss of muscle mass and function: Where should we be focusing?

Ham, D. J., Fry, C. S., Ruparelia, A. A., Ngo, S. T., & Lamon, S. (2026) · The Journal of Physiology · doi:10.1113/jp289838 · Cited by 5 · see citing works

Clinical Application and Immune Infiltration Landscape of Stemness-Related Genes in Heart Failure

Yan, W., Li, Y., Wang, G., Huang, Y., & Xie, P. (2024) · ESC Heart Failure · doi:10.1002/ehf2.15055 · Cited by 4 · see citing works

Reorganization of pancreas circadian transcriptome with aging

Sharma, D., Wessel, C. R., Mahdavinia, M., Preuss, F., & Bishehsari, F. (2023) · Aging · doi:10.18632/aging.204929 · Cited by 4 · see citing works

Muscle stem cell niche dynamics during muscle homeostasis and regeneration

Yin, Y., He, G. J., Hu, S., Tse, E. H. Y., & Cheung, T. H. (2024) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2024.02.008 · Cited by 3 · see citing works

The Evolving Field of Regenerative Aesthetics: A Review and Case Series

Corduff, N., Goldie, K., Lin, F. G., Lowe, S., Siew, T. W., Vachiramon, V., Chao, Y. Y. Y., Lesthari, N. I., Ong-Amoranto, B., Lim, T. S., et al. (2025) · Cureus · doi:10.7759/cureus.87878 · Cited by 3 · see citing works

Age-related changes in quadriceps stiffness and strength: a longitudinal observation in community-dwelling older adults

Li, Z., Huang, X., Chung, R. C. K., Leung, K. L., & Fu, S. N. (2025) · BMC Geriatrics · doi:10.1186/s12877-025-06657-3 · Cited by 3 · see citing works

High-Throughput Contractile Measurements of Hydrogel-Embedded Intact Mouse Muscle Fibers Using an Optics-Based System

Vonk, L. A., Esen, O., Yuen, M., & Kirby, T. J. (2023) · Journal of Visualized Experiments · doi:10.3791/65103 · Cited by 3 · see citing works

Autophagy is dispensable in germline stem cells but is required in the cap cells for their maintenance in the Drosophila ovarian niche

Nilangekar, K. S., & Shravage, B. V. (2025) · Stem Cell Reports · doi:10.1016/j.stemcr.2025.102712 · Cited by 3 · see citing works

Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation

Späth, E., Schüler, S. C., Heinze, I., Dau, T., Minetti, A., Hofmann, M., Hönzke, K., von Maltzahn, J., & Ori‬‬, A. (2026) · eLife · doi:10.7554/elife.104331.3 · Cited by 3 · see citing works

Tissue-resident skeletal muscle macrophages promote recovery from viral pneumonia-induced sarcopenia in normal agingPreprint

Runyan, C. E., Luo, L., Welch, L. C., Lu, Z., Chen, F., Schleck, M. J., Nafikova, R. A., Grant, R. A., Aillon, R. P., Senkow, K. J., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.09.631996 · Cited by 4 · see citing works

Matricellular protein SMOC2 safeguards tubular integrity in acute kidney injury via integrin β3-dependent inhibition of CCND1-CDK4/6 axis

Gao, P., Cenatus, S., Zhang, D., Chu, S., Henley, N., Pichette, V., Barrera‐Chimal, J., & Gerarduzzi, C. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00407-6 · Cited by 2 · see citing works

The hallmarks of skeletal muscle health

Vainshtein, A., Blaauw, B., Bock, K. D., Muñoz‐Cánoves, P., Olson, E. N., Ottenheijm, C. A. C., Richter, E. A., Ruas, J. L., Schaeffer, L., Spiegelman, B. M., et al. (2026) · Nature Metabolism · doi:10.1038/s42255-026-01595-9 · Cited by 3 · see citing works

Role of pulmonary rehabilitation in extracellular matrix protein expression in vastus lateralis muscle in atrophic and nonatrophic patients with COPD

Kritikaki, E., Terzis, G. D., Soundararajan, M., Vogiatzis, I., & Simoes, D. C. M. (2024) · ERJ Open Research · doi:10.1183/23120541.00543-2024 · Cited by 2 · see citing works

Plasma Proteomic Signature as a Predictor of Age Advancement in People Living With HIV

Navas, A., Matzaraki, V., van Eekeren, L. E., Blaauw, M. J. T., Groenendijk, A. L., Vos, W. A. J. W., Cleophas, M. C. P., dos Santos, J. C., van der Ven, A. J. A. M., Joosten, L. A. B., et al. (2025) · Aging Cell · doi:10.1111/acel.14468 · Cited by 2 · see citing works

Strategy for drug repurposing in fibroadipogenic replacement during muscle wasting: application to duchenne muscular dystrophy

Matthews, I., Mehra, P., Suárez‐Calvet, X., Piñol‐Jurado, P., Cox, D., Justian, V., Carrasco‐Rozas, A., Laidler, Z., Bowey, A. J., Rushton, P. R. P., et al. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1505697 · Cited by 2 · see citing works

Dynamical modeling reveals RNA decay mediates the effect of matrix stiffness on aged muscle stem cell fatePreprint

Hettinger, Z. R., Hu, S., Mamiya, H., Sahu, A., Iijima, H., Wang, K., Gilmer, G. G., Miller, A. K., Nasello, G., D’Amore, A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.24.529950 · Cited by 2 · see citing works

Aging in the Skeletal Muscle Revealed by Molecular Immunohistochemical Imaging

Malatesta, M., & Cisterna, B. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26135986 · Cited by 1 · see citing works

Extracellular matrix-associated molecules of senescent cells induce a senescence phenotype in proliferative cells via TGF-β signaling pathway

Ferreira, R. S., Aires, H. I. R., Rebelo, C., Passos, J. F., Ori‬‬, A., Pitrez, P. R., & Ferreira, L. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124117 · Cited by 1 · see citing works

RUNX1T1 enhances intramuscular fat deposition in pigs through promoting fibro-adipogenic progenitors adipogenesis via PI3K-AKT and MAPK signaling pathways

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ADAMTS4 Reduction Contributes to Extracellular Matrix Deposition and Impaired Myogenesis in the Skeletal Muscle of Cigarette Smoke-Exposed Mice

Li, D., Pei, Y., Liang, L., Wang, Z., Gai, X., & Sun, Y. (2025) · Biomedicines · doi:10.3390/biomedicines13020474 · Cited by 1 · see citing works

BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermisPreprint

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Aging-associated impairment of muscle mechanosensitivity: Implications for muscle protein synthesis and regeneration

Haroon, M. (2023) · doi:10.5463/thesis.123

JoVE Video Dataset

Vonk, L. A., Esen, O., Yuen, M., & Kirby, T. J. (2023) · doi:10.3791/65103-v

Quantification of local matrix deposition during muscle stem cell activation using engineered hydrogelsPreprint

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Mitochondrial Alterations and Signaling in Aging, Frailty, and Sarcopenia: An Integrated View

Picca, A., González‐Freire, M., Anton, S. D., Marzetti, E., & Leeuwenburgh, C. (2024) · Springer eBooks · doi:10.1007/978-3-031-57361-3_14

Analyzing Muscle Stem Cell Function Ex Vivo

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Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiationPreprint

Späth, E., Schüler, S. C., Heinze, I., Dau, T., Minetti, A., Hofmann, M., Hönzke, K., von Maltzahn, J., & Ori‬‬, A. (2025) · eLife · doi:10.7554/elife.104331

Multiomics profiling of zebrafish embryonic cell line PAC2 across growth phases to assess its relevance for toxicological studies

Degeratu, M.-O., Bertoli, J., Huwa, N., Rodríguez, D. L., Revel, M., Schönenberger, R., Berg, C. V., Schirmer, K., & Groh, K. J. (2026) · PLoS ONE · doi:10.1371/journal.pone.0346109

Clinical Application and Regulation in Stem Cells

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Rejuvenation-Responsive and Senolytic-Sensitive Muscle Stem Cells Unveiled by CD200 and CD63 in Geriatric MusclePreprint

Kim, Y. L., Jo, Y.-W., Yoo, T., Yoo, K., Kim, J.-H., Park, M., Song, I.-W., Kim, H., Kim, Y.-E., Hann, S., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.29.673011

Distinct Intramuscular Extracellular Matrix Protein Responses to Exercise Training in COPD and Healthy Adults and Their Association with Muscle Remodeling

Simoes, D. C. M., Kritikaki, E., Terzis, G. D., & Vogiatzis, I. (2025) · Cells · doi:10.3390/cells14211656

Rejuvenation-Responsive and Senolytic-Sensitive Muscle Stem Cells Unveiled by CD200 and CD63 in Geriatric MusclePreprint

Kim, Y. L., Jo, Y., Yoo, T., Yoo, K., Kim, J.-H., Park, M., Song, I.-W., Kim, H. J., Kim, Y.-E., Hann, S., et al. (2025) · eLife · doi:10.7554/elife.108680

Rejuvenation-Responsive and Senolytic-Sensitive Muscle Stem Cells Unveiled by CD200 and CD63 in Geriatric MusclePreprint

Kim, Y. L., Jo, Y., Yoo, T., Yoo, K., Kim, J.-H., Park, M., Song, I.-W., Kim, H., Kim, Y.-E., Hann, S., et al. (2025) · eLife · doi:10.7554/elife.108680.1

Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiationPreprint

Späth, E., Schüler, S. C., Heinze, I., Dau, T., Minetti, A., Hofmann, M., Hönzke, K., von Maltzahn, J., & Ori‬‬, A. (2026) · eLife · doi:10.7554/elife.104331.2

Rejuvenation-Responsive and Senolytic-Sensitive Muscle Stem Cells Unveiled by CD200 and CD63 in Geriatric MusclePreprint

Kim, Y. L., Jo, Y. K., Yoo, T., Yoo, K., Kim, J., Park, M., Song, I.-W., Kim, H., Kim, Y.-E., Hann, S., et al. (2026) · eLife · doi:10.7554/elife.108680.2

Targeting the Skeletal Muscle Microenvironment: A Novel Therapeutic Strategy for Skeletal Muscle Aging

Yu, Y., He, Y., Wang, Y., Wu, C., Zhou, R., Chen, F., & Ma, W. (2026) · The FASEB Journal · doi:10.1096/fj.202601360r

p38MAP kinase regulates senescence in human iPS-derived myocytes

Sato, H., Arakane, M., Mizuno, Y., Sasaki, T., Sakurai, H., Kamihira, M., Enomoto, A., Takafuji, K., Takaya, J., Suzuki, T., et al. (2026) · Aging · doi:10.18632/aging.206385

Decoding exercise-induced delayed aging from a single-cell perspective

Zhao, Y., Zhou, X., & Ni, T. (2026) · Advanced Exercise and Health Science · doi:10.1016/j.aehs.2026.05.001

The Impact of Ageing on Skeletal Muscle: Roles of Mitochondrial Dysregulation, Systemic Communication, and Exercise

Hernández‐Camacho, J. D., & Saclier, M. (2026) · Journal of Cellular Physiology · doi:10.1002/jcp.70212

Beyond hormone deficiency: a framework for endocrine-immune-niche integration in aging skeletal muscle regeneration

Perin, L., Sacco, S. D., Liu, Y., Brent, G. A., & Milanesi, A. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1906969

Decline of regenerative potential of old muscle stem cells: contribution to muscle aging

Sahinyan, K., Lazure, F., Blackburn, D. M., & Soleimani, V. D. (2022) · FEBS Journal · doi:10.1111/febs.16352 · Cited by 25 · see citing works

Aging remodels the human muscle secretome, impairing stem cell via sphingolipid metabolismPreprint

Crisol, B., Pinzón, N., Bensalah, M., Ohana, J., Lhomme, M., Ponnaiah, M., Bruce, J., Kondili, M., Gaut, L., Négroni, E., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.01.755640

Skeletal muscle aging – Stem cells in the spotlight

Henze, H., Jung, M. J., Ahrens, H. E., Steiner, S., & von Maltzahn, J. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111283 · Cited by 28 · see citing works

Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice

Lukjanenko, L., Jung, M. J., Hegde, N., Perruisseau-Carrier, C., Migliavacca, E., Rozo, M., Karaz, S., Jacot, G. E., Schmidt, M., Li, L., et al. (2016) · Nature Medicine · doi:10.1038/nm.4126 · Cited by 337 · see citing works

Reversal of Aged Muscle Stem Cell Dysfunction

Larrick, J. W., Larrick, J. W., & Mendelsohn, A. R. (2016) · Rejuvenation Research · doi:10.1089/rej.2016.1875 · Cited by 4 · see citing works