Current methods and new directions in resting state fMRI
Open accessAbstract
Resting state functional connectivity magnetic resonance imaging (rsfcMRI) has become a key component of investigations of neurocognitive and psychiatric behaviors. Over the past two decades, several methods and paradigms have been adopted to utilize and interpret data from resting-state fluctuations in the brain. These findings have increased our understanding of changes in many disease states. As the amount of resting state data available for research increases with big datasets and data-sharing projects, it is important to review the established traditional analysis methods and recognize areas where research methodology can be adapted to better accommodate the scale and complexity of rsfcMRI analysis. In this paper, we review established methods of analysis as well as areas that have been receiving increasing attention such as dynamic rsfcMRI, independent vector analysis, multiband rsfcMRI and network of networks.
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- Authors
- Yang, J., Gohel, S., & Vachha, B.
- Affiliations
- New York University (US)
- Rutgers, The State University of New Jersey (US)
- Memorial Sloan Kettering Cancer Center (US)
- Corresponding author
- Vachha, Behroze
- Venue
- Clinical Imaging
- Publisher
- Elsevier BV
- Published
- 2020-09
- Volume
- 65
- Pages
- 47-53
- ISSN
- 0899-7071 (ISSN-L)
- PMC
- PMC7365764
- OpenAlex
- W3015866295
- Cited by
- 110
- References
- 114
- Citations by year
- 2026: 15 · 2025: 26 · 2024: 15 · 2023: 19 · 2022: 16 · 2021: 15 · 2020: 4
- FWCI
- 1.82
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Imaging (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Keywords
- resting-state fMRI, functional connectivity, dynamic functional connectivity, independent vector analysis, network of networks, brain network analysis
- MeSH terms
- Adult, Brain, Brain Mapping, Female, Humans, Magnetic Resonance Imaging, Male, Nerve Net, Rest
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