Insulin Action in AgRP-Expressing Neurons Is Required for Suppression of Hepatic Glucose Production

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

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A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance

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NPY/AgRP Neurons Are Essential for Feeding in Adult Mice but Can Be Ablated in Neonates

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Divergence of Melanocortin Pathways in the Control of Food Intake and Energy Expenditure

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Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

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Hypothalamic insulin signaling is required for inhibition of glucose production

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Diabetes, Obesity, and the Brain

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Agouti-related peptide–expressing neurons are mandatory for feeding

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Hypothalamic ΔFosB prevents age-related metabolic decline and functions via SNS

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Jinkui Shenqi pills ameliorate diabetes by regulating hypothalamic insulin resistance and POMC/AgRP expression and activity

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Brain Defense of Glycemia in Health and Diabetes

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Insulin activates parasympathetic hepatic-related neurons of the paraventricular nucleus of the hypothalamus through mTOR signaling

dos Santos, K. M., Saunders, S. E., Antunes, V. R., & Boychuk, C. R. (2024) · Journal of Neurophysiology · doi:10.1152/jn.00284.2024 · Cited by 9

PKCθ over expression in the central nucleus of the amygdala or hypothalamus has differential effects on energy balance and peripheral glucose homeostasis

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Feeding signals to the hungry mind

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Harnessing the melanocortin system in the control of food intake and glucose homeostasis

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NMDA Receptors in POMC Neurons Connect Exercise With Insulin Sensitivity

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Exploring the pathways linking fasting insulin to coronary artery disease: a proteome-wide Mendelian randomization study

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Neural gut-to-brain communication for postprandial control of satiation and glucose metabolism

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Glucagon and lipid signaling in the hypothalamus

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The Melanocortin Signal System of the Hypothalamus and Its Functional State in Type 2 Diabetes Mellitus and Metabolic Syndrome

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Plasma Agouti-Related Protein Levels in Acromegaly and Effects of Surgical or Pegvisomant Therapy

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Diet-Induced Metabolic Dysfunction of Hypothalamic Nutrient Sensing in Rodents

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Roles of calcium and Mitochondria-Associated Membranes in the development of obesity and diabetes

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Potential Roles of O-GlcNAcylation in Primary Cilia- Mediated Energy Metabolism

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Neuroendocrine microRNAs linked to energy homeostasis: future therapeutic potential

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Reduced Notch signaling in hypothalamic endothelial cells mediates obesity-induced alterations in glucose uptake and insulin signaling

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Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons

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AgRP Neuron-Specific Ablation Represses Appetite, Energy Intake, and Somatic Growth in Larval Zebrafish

Lin, C.-Y., Yeh, K., Lai, H.-H., & Her, G. M. (2023) · Biomedicines · doi:10.3390/biomedicines11020499 · Cited by 5

Chemogenetic engagement of different GPCR signaling pathways segregates the orexigenic activity from the control of whole-body glucose metabolism by AGRP neurons

Abreu, V. E., Barnes, R., Borra, V. J., Schurdak, J. D., & Pérez–Tilve, D. (2024) · Molecular Metabolism · doi:10.1016/j.molmet.2024.102079 · Cited by 5

Intranasal Insulin Administration Does Not Affect LH Concentrations in Men with Diabetes

Dhindsa, S., Chemitiganti, R., Ghanim, H., Santiago, E., Haider, A., Natalia, C., Mok, M., McKee, A. M., & Dandona, P. (2018) · International Journal of Endocrinology · doi:10.1155/2018/6170154 · Cited by 5

The effect of human wharton's jelly-derived mesenchymal stem cells on MC4R, NPY, and LEPR gene expression levels in rats with streptozotocin-induced diabetes.

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Insulin as a neuroendocrine hormone

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Differential Gene Expression and Biological Analyses of Primary Hepatocytes Following D-Chiro-Inositol Supplement

Cheng, F., Yun, S., Cao, J., Chang, M., Meng, J., Liu, J., Cheng, Y., & Feng, C. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.700049 · Cited by 5

Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice

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Control of physiologic glucose homeostasis via hypothalamic modulation of gluconeogenic substrate availability

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Reversal of diet-induced obesity by central insulin sensitizer FSTL1

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Title: p38δ Regulates IL6 Expression Modulating ERK Phosphorylation in Preadipocytes

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Central Administration of the Ciliary Neurotrophic Factor Analogue, Axokine, Does Not Play a Role in Long-Term Energy Homeostasis in Adult Mice

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Glucose Metabolism and Liver

Hashimoto, S. (2016) · Springer eBooks · doi:10.1007/978-4-431-55790-6_5 · Cited by 4

Males Require Estrogen Signaling Too: Sexual Dimorphism in the Regulation of Glucose Homeostasis by Nuclear ERα

Alejandro, E. U. (2019) · Diabetes · doi:10.2337/dbi18-0046 · Cited by 4

The Role of Brain in Glucose Metabolism

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Impact of Brain Fatty Acid Signaling on Peripheral Insulin Action in Mice

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The Obese Brain

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Kisspeptin system–physiology and clinical perspectives

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Dietary strategies targeting the interplay between obesity and neurodegenerative disease pathogenesis

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Oxidative and endoplasmic reticulum stress in b-cell dysfunction in diabetes

Hasnain, S. Z., Prins, J. B., & McGuckin, M. A. (2016) · Cited by 3

Electrophysiological Mechanism of Peripheral Hormones and Nutrients Regulating Energy Homeostasis

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Charge Characteristics of Agouti-Related Protein Implicate Potent Involvement of Heparan Sulfate Proteoglycans in Metabolic Function

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Serotonergic neurons are involved in the counter‐regulatory response to hypoglycemia

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Age-Related Dynamics of Insulin Signaling in Neurons of the Rat Hypothalamic Tuberal Nuclei

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Cellular Profile of Subfornical Organ Insulin Receptors in Mice

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Antipsychotic-Induced Dysregulation of Glucose Metabolism Through the Central Nervous System: A Scoping Review of Animal Models

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Metabolism and satiety

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Vitamin D and the paraventricular nucleus: Relevance for type 2 diabetes

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Long-term administration of intranasal insulin improves peripheral glucose concentration in diabetic male rats

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Central Regulation of Appetite and Satiety Behavior

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Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticityPreprint

Thomas, W. R., Richter, T. A., O’Neil, E. T., Baldoni, C., Corthals, A., von Elverfeldt, D., Nieland, J. D., Dechmann, D. K. N., Hunter, R. G., & Dávalos, L. M. (2024) · eLife · doi:10.7554/elife.100788 · Cited by 3

Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticityPreprint

Thomas, W. R., Richter, T. A., O’Neil, E. T., Baldoni, C., Corthals, A., von Elverfeldt, D., Nieland, J. D., Dechmann, D. K. N., Hunter, R. G., & Dávalos, L. M. (2024) · eLife · doi:10.7554/elife.100788.1 · Cited by 3

Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticity

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Whispering Through the Barrier: Signaling Interfaces for Peripheral Regulation of Brain Function in Obesity

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Post-stroke osteoporosis: Mechanisms, treatments, and recent advances

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Systemic Glucose Homeostasis Requires Pancreatic but Not Neuronal ATP-sensitive Potassium Channels

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Glucose and energy metabolism are impaired in mice deficient for orexins

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Central glucose sensing

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Neuropeptides Controlling Our Behavior

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Hypothalamic Control of Appetite and Energy Metabolism

Reichenbach, A., Stark, R., & Andrews, Z. B. (2013) · Cited by 2

Estradiol Protects Hypothalamic Neurons Against Insulin Resistance

Rønnekleiv, O. K., & Kelly, M. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-813156-5.00015-7 · Cited by 2

Endocrinal Association of Hypothalamic-Pituitary-Adrenal (HPA) Axis with Obesity

Sohail, K., Aiman, U. E., Younis, S., & Deeba, F. (2020) · THE JOURNAL OF MICROBIOLOGY AND MOLECULAR GENETICS · doi:10.52700/jmmg.v1i2.16 · Cited by 2

Neuronal Ptpn1 and Socs3 deletion improves metabolism but not anovulation in a mouse polycystic ovary syndrome model

Kerbus, R. I., Inglis, M. A., & Anderson, G. M. (2023) · Journal of Endocrinology · doi:10.1530/joe-23-0023 · Cited by 2

Insulin signalling activates multiple feedback loops to elicit hunger-induced feeding in DrosophilaPreprint

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Carbohydrate and Protein Metabolism: Influences on Cognition and Alzheimer's Disease

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Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistancePreprint

Skovsø, S., Panzhinskiy, E., Kolic, J., Cen, H. H., Dionne, D. A., Dai, X.-Q., Sharma, R. B., Elghazi, L., Ellis, C. E., Faulkner, K., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.15.338160 · Cited by 2

Hormones and the Regulation of Neuronal Voltage-Sensing Ion Channels

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Wiring the Brain for Wellness: Sensory Integration in Feeding and Thermogenesis: A Report on Research Supported by Pathway to Stop Diabetes

Riera, C. E. (2024) · Diabetes · doi:10.2337/db23-0706 · Cited by 1

Brain-Body Communication in Glucose Metabolism

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A hypothalamic circuit for anticipating future changes in energy balance

Walker, S. J., Lowenstein, E. D., Douglass, A. M., Thomas, C. M. P., Madara, J. C., Kucukdereli, H., Barbosa-Meillon, E. A., Tao, J., Resch, J. M., & Lowell, B. B. (2026) · Neuron · doi:10.1016/j.neuron.2026.05.010 · Cited by 1

Insights into the mechanisms of body weight control

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Protein kinase C epsilon deletion in AgRP neurons modulates hypothalamic glucose sensing and improves glucose tolerance in mice

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PCB-126 exposure promotes brown adipose tissue dysfunction and metabolic inflexibility in mice

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Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

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Getting AGRP on obesity

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Regulation of glucose metabolism by central insulin action

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Neural Control of Feeding and Energy Homeostasis

Caron, É., & Ahima, R. S. (2010) · Springer eBooks · doi:10.1007/978-1-4419-1607-5_5 · Cited by 1

Food Intake and Its Control by Signaling Molecules

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The Effects of Insulin on Spike Activity of the Suprachiasmatic Nucleus Neurones and Functional State of Afferent Inputs from the Arcuate Nucleus in Rats

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Insulin Preferentially Regulates the Activity of Parasympathetic Preganglionic Neurons over Sympathetic Preganglionic Neurons

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Sugar, Stress, and Metabolism

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Fatty Acids and Hypothalamic Dysfunction in Obesity

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Obesity and Stress: The Melanocortin Connection

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Effects of Metabolic Surgery on Glucose Homeostasis in Type 2 Diabetes

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VOXEL-WISE ANALYSES OF THE IMPACT OF HIGH-FAT DIET ON BRAIN STRUCTURE IN WISTAR RATS

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Beta-cell specific insulin resistance promotes glucose-stimulated insulin hypersecretion [preprint]

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The infundibular peptidergic neurons and glia cells in overeating, obesity, and diabetes

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The role of the hypothalamus in the maintenance of energy balance and peripheral glucose control

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