The DOI matches its Crossref record; 208 of the 210 references it cites were found in a registry or an index.
Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation
Open accessAbstract
Preservation of aerobic fitness and skeletal muscle strength through exercise training can ameliorate metabolic dysfunction and prevent chronic disease. These benefits are mediated in part by extensive metabolic and molecular remodeling of skeletal muscle by exercise. Aerobic and resistance exercise represent extremes on the exercise continuum and elicit markedly different training responses that are mediated by a complex interplay between a myriad of signaling pathways coupled to downstream regulators of transcription and translation. Here, we review the metabolic responses and molecular mechanisms that underpin the adaptatation of skeletal muscle to acute exercise and exercise training.
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In the citing paper
“This is principally achieved by an augmentation in mitochondrial volume, FA transport and enzymatic adaptations (e.g., increase hydroacyl-CoA-dehydrogenase) to use fat, and a reduction of cell signals such as ADP and AMP during exercise at submaximal work rates thus reducing the activation of key enzymes (e.g., glycogen phosphorylase and pyruvate dehydrogenase) of carbohydrate metabolism [92,160].”
From Regulation of Energy Substrate Metabolism in Endurance Exercise (2021) · cites this paper as [160]
In the citing paper
“Exercise promotes glucose uptake and glycogen synthesis and increases insulin sensitivity, and this persists long after the cessation of exercise (1, 2).”
From Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance (2021) · cites this paper as [2]
In the citing paper
“The induction of PGC1α (peroxisome proliferator–activated receptor gamma coactivator 1α) after exercise can promote mitochondrial biogenesis by driving the expression of nuclear- and mitochondrial-encoded genes.”
From Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance (2021) · cites this paper as [2]
In the citing paper
“The enhanced skeletal muscle insulin sensitivity after exercise affords metabolic flexibility and a means for replenishing glycogen to deal with subsequent bouts of intense physical activity (1, 2).”
From Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance (2021) · cites this paper as [2]
In the citing paper
“Exercise results in skeletal muscle exposure to acute stresses that stimulate compensatory and adaptive physiological responses (1, 2).”
From Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance (2021) · cites this paper as [2]
In the citing paper
“These adaptive responses increase tolerance and protect against subsequent stressors and are considered important for the health-promoting effects of exercise (1, 2).”
From Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance (2021) · cites this paper as [2]
In the citing paper
“In particular, PGC1α promotes the expression of NRF (nuclear respiratory factor)–1 and NRF-2, which induce the expression of nuclear-encoded genes, as well as TFAM (mitochondrial transcription factor A), which facilitates mitochondrial DNA transcription and replication (2, 3).”
From Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance (2021) · cites this paper as [2]
In the citing paper
“A fundamental hormetic response to exercise is the induction of mitochondrial biogenesis, which serves to enhance respiratory capacity and endurance (2, 3).”
From Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance (2021) · cites this paper as [2]
In the citing paper
“It is well established that contracting muscle generates ROS and that this is accompanied by increased antioxidant defense orchestrated by NFE2L2 (2, 7, 36).”
From Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance (2021) · cites this paper as [2]
In the citing paper
“These observations confirm the hypothesis that endurance exercise training may affect a specific set of functions (e.g., oxidative metabolism and mitochondrial biogenesis) and overall muscle metabolism [93].”
From Role of Age-Related Mitochondrial Dysfunction in Sarcopenia (2020) · cites this paper as [93]
In the citing paper
“Multiple molecular pathways are activated by exercise and these pathways have been shown to contribute to the adaptive remodelling of skeletal muscle [1,2].”
From New strategies in sport nutrition to increase exercise performance (2016) · cites this paper as [2]
In the citing paper
“These adaptive processes are driven by transcriptional changes in response to each bout of exercise [2,8].”
From New strategies in sport nutrition to increase exercise performance (2016) · cites this paper as [2]
In the citing paper
“The transcriptional changes accumulate over time such that the protein expression profile of muscle is changed resulting in an altered phenotype [2,8].”
From New strategies in sport nutrition to increase exercise performance (2016) · cites this paper as [2]
In the citing paper
“Whilst endurance exercise adaptations are believed to be driven primarily by transcriptional responses [2,8], the muscle growth adaptation to resistance exercise is driven primarily by changes in translation, in particular by increases in mRNA activity (protein produced per unit of mRNA) [85][86][87].”
From New strategies in sport nutrition to increase exercise performance (2016) · cites this paper as [2]
In the citing paper
“It is a key factor in metabolism of all major biomolecules (lipids, carbohydrates, amino acids) as well as ATP synthesis by the electron transport chain [164, 165]”
From Targeting Intramyocellular Lipids to Improve Aging Muscle Function (2025) · cites this paper as [165]
In the citing paper
“A higher mitochondrial volume density and improved mitochondrial quality can be seen as consequences of chronic activation of AMPK and expression induction of PGC1α, myocyte-specific enhancer factor 2 (MEF2), NRF-1 and NRF-2, and nuclear expulsion of histone deacetylase 4 and 5 (41, 222, 224).”
From Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease (2018) · cites this paper as [222]
In the citing paper
“Additionally, PGC1α is expressed upon muscle contraction-induced activation of p38 MAPK (222).”
From Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease (2018) · cites this paper as [222]
In the citing paper
“Both promote considerable health benefits such as increased mitochondrial content and improvements in glycemic control (222).”
From Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease (2018) · cites this paper as [222]
In the citing paper
“Acute AMPK activation reduces glycogen and protein synthesis while promoting glucose transport and FAO (222).”
From Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease (2018) · cites this paper as [222]
In the citing paper
“Because exercise and ApN share similar signaling pathways [75,76] and the potential of counteracting several facets of this metabolic syndrome, numerous studies attempted to establish relationships between exercise and ApN parameters.”
From Adiponectin and Its Mimics on Skeletal Muscle: Insulin Sensitizers, Fat Burners, Exercise Mimickers, Muscling Pills … or Everything Together? (2020) · cites this paper as [76]
Citations
Cites
2 retracted
Safdar, A., Little, J. P., Stokl, A., Hettinga, B. P., Akhtar, M., & Tarnopolsky, M. A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.211466 · Cited by 321
RetractedSafdar, A., Bourgeois, J. M., Ogborn, D. I., Little, J. P., Hettinga, B. P., Akhtar, M., Thompson, J. E., Melov, S., Mocellin, N. J., Kujoth, G. C., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019581108 · Cited by 320
RetractedReduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012512 · Cited by 19,011 · cited 4×
“In fact, regular exercise combined with dietary intervention is more successful than pharmacological intervention in the treatment and prevention of T2DM (Knowler et al., 2002) and sarcopenia (Borst, 2004).”
BackgroundInfluentialThe functions of animal microRNAs
Ambros, V. (2004) · Nature · doi:10.1038/nature02871 · Cited by 10,728
Global physical activity levels: surveillance progress, pitfalls, and prospects
Hallal, P. C., Andersen, L. B., Bull, F. C., Guthold, R., Haskell, W., & Ekelund, U. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60646-1 · Cited by 5,711
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
Maxwell, P. H., Wiesener, M. S., Chang, G.-W., Clifford, S. C., Vaux, E. C., Cockman, M. E., Wykoff, C. C., Pugh, C. W., Maher, E. R., & Ratcliffe, P. J. (1999) · Nature · doi:10.1038/20459 · Cited by 5,180
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., Long, J. Z., et al. (2012) · Nature · doi:10.1038/nature10777 · Cited by 4,810
HASKELL, W. L., LEE, I.-M., PATE, R. R., POWELL, K. E., BLAIR, S. N., FRANKLIN, B. A., MACERA, C. A., HEATH, G. W., THOMPSON, P. D., & BAUMAN, A. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3180616b27 · Cited by 4,616
Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80611-x · Cited by 4,139
Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057
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Mallett, G. S. (2025) · European Journal of Applied Physiology · doi:10.1007/s00421-025-05704-6 · Cited by 23
Šket, R., Treichel, N. S., Kublik, S., Debevec, T., Eiken, O., Mekjavić, I. B., Schloter, M., Vital, M., Chandler, J., Tiedje, J. M., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0188556 · Cited by 22
Raizel, R., & Tirapegui, J. (2018) · Nutrire · doi:10.1186/s41110-018-0087-9 · Cited by 24
Zhou, H., Xiang, Y., Hu, M., Xu, Y., Hou, Y., Qi, X., Fu, L., Luan, Y., Wang, Z., Li, X., et al. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-2341-3 · Cited by 22
Żebrowska, A., Sikora, M., Konarska-Rawluk, A., Zwierzchowska, A., Kamiński, T., Robins, A., & Hall, B. (2020) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/2042018820925326 · Cited by 24
Danaher, J., Stathis, C. G., Wilson, R. A., Moreno‐Asso, A., Wellard, R. M., & Cooke, M. B. (2020) · Nutrition & Metabolism · doi:10.1186/s12986-020-00489-1 · Cited by 22
Yamada, T., Kimura, I., Ashida, Y., Tamai, K., Fusagawa, H., Tohse, N., Westerblad, H., Andersson, D. C., & Sato, T. (2021) · The FASEB Journal · doi:10.1096/fj.202101204r · Cited by 22
Emanuelsson, E. B., Arif, M., Reitzner, S. M., Perez, S., Lindholm, M. E., Mardinoğlu, A., Daub, C. O., Sundberg, C. J., & Chapman, M. A. (2023) · iScience · doi:10.1016/j.isci.2023.108638 · Cited by 24
Done, A. J., & Traustadóttir, T. (2016) · AGE · doi:10.1007/s11357-016-9942-x · Cited by 22
Gonzalez, A. M., Ghigiarelli, J. J., Sell, K. M., Shone, E. W., Kelly, C. F., & Mangine, G. T. (2016) · Muscle & Nerve · doi:10.1002/mus.25509 · Cited by 22
Context is key: exogenous ketosis and athletic performance
Dearlove, D., Harrison, O. K., & Clarke, K. (2019) · Current Opinion in Physiology · doi:10.1016/j.cophys.2019.04.010 · Cited by 21
Qi, J., Luo, X., Ma, Z., Zhang, B., Li, S., Duan, X., Yang, B., & Zhang, J. (2020) · Journal of Diabetes Research · doi:10.1155/2020/2521590 · Cited by 22
RetractedRamos, P. M., Li, C., Elzo, M. A., Wohlgemuth, S. E., & Scheffler, T. L. (2020) · Journal of Animal Science · doi:10.1093/jas/skaa044 · Cited by 22
Sun, Y., Yang, Z.-X., Ren, F., & Fang, B. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.04.186 · Cited by 22
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Tsiloulis, T., Pike, J., Powell, D., Rossello, F. J., Canny, B. J., Meex, R. C. R., & Watt, M. J. (2016) · The FASEB Journal · doi:10.1096/fj.201600678r · Cited by 22
Wang, T., Sun, X., Zhang, Y., Wang, Q., Cheng, W., Gao, Y., Shi, X., & Jin, J. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c00300 · Cited by 21
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Ma, J., Wang, H., Liu, R., Jin, L. G., Tang, Q., Wang, X., Jiang, A., Hu, Y., Li, Z., Zhu, L., et al. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16059635 · Cited by 21
Hiroux, C., Vandoorne, T., Koppo, K., Smet, S. D., Hespel, P., & Berardi, E. (2016) · European Journal of Translational Myology · doi:10.4081/ejtm.2016.5958 · Cited by 21
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Renzini, A., Riera, C. S., Minic, I., D’Ercole, C., Lozanoska‐Ochser, B., Cedola, A., Gigli, G., Moresi, V., & Madaro, L. (2021) · Metabolites · doi:10.3390/metabo11080517 · Cited by 22
Aird, T. P., Farquharson, A. J., Bermingham, K. M., O’Sullivan, A. M., Drew, J. E., & Carson, B. P. (2021) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00265.2021 · Cited by 22
Strom, C. J., McDonald, S. M., Remchak, M. E., Kew, K. A., Rushing, B. R., Houmard, J. A., Tulis, D. A., Pawlak, R., Kelley, G. A., Chasan‐Taber, L., et al. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063550 · Cited by 21
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Yamada, T., Ashida, Y., Tamai, K., Kimura, I., Yamauchi, N., Naito, A., Tokuda, N., Westerblad, H., Andersson, D. C., & Himori, K. (2022) · Arthritis Research & Therapy · doi:10.1186/s13075-022-02846-2 · Cited by 21
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Basten, A. M., Raymond‐Pope, C. J., Hoffman, D. B., Call, J. A., & Greising, S. M. (2022) · Experimental Physiology · doi:10.1113/ep090630 · Cited by 21
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Enoki, Y., Nagai, T., Hamamura, Y., Osa, S., Nakamura, H., Taguchi, K., Watanabe, H., Maruyama, T., & Matsumoto, K. (2022) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13159 · Cited by 21
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Silva, V. R. R., Katashima, C. K., Silva, C. G. B., Lenhare, L., Micheletti, T. O., Camargo, R. L., Ghezzi, A. C., de Camargo, J. A., Moura‐Assis, A., Tobar, N., et al. (2016) · Aging · doi:10.18632/aging.101138 · Cited by 21
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Danilov, K. A., Sidorenko, S. V., Милованова, К. Г., Климанова, Е. А., Капилевич, Л. В., & Orlov, S. N. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.09.133 · Cited by 21
Archer, E., Pavela, G., McDonald, S. M., Lavie, C. J., & Hill, J. O. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01053 · Cited by 23
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Mayr, B., Müller, E. E., Schäfer, C., Droese, S., Breitenbach‐Koller, H., Schönfelder, M., & Niebauer, J. (2018) · European Journal of Preventive Cardiology · doi:10.1177/2047487318808014 · Cited by 20
Heckel, Z., Atlasz, T., Tékus, É., Kőszegi, T., Laczkó, J., & Váczi, M. (2019) · PLoS ONE · doi:10.1371/journal.pone.0224866 · Cited by 21
Hardee, J. P., Fix, D. K., Koh, H., Wang, X., Goldsmith, E. C., & Carson, J. A. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00908.2019 · Cited by 21
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Marš, T., Miš, K., Meznarič, M., Mihevc, S. P., Jan, V., Haugen, F., Rogelj, B., Rustan, A. C., Thoresen, G. H., Pirkmajer, S., et al. (2020) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2019-0575 · Cited by 21
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Soñanez‐Organis, J. G., Godoy-Lugo, J. A., Hernandez‐Palomares, M. L. E., Rodríguez-Martínez, D., Rosas‐Rodríguez, J. A., González-Ochoa, G., Virgen‐Ortiz, A., & Ortiz, R. M. (2016) · Gene · doi:10.1016/j.gene.2016.06.025 · Cited by 21
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Bittel, A. J., Bohnert, K. L., Reeds, D. N., Peterson, L. R., Fuentes, L. D. L., Corti, M., Taylor, C. L., Byrne, B. J., & Cade, W. T. (2018) · JIMD Reports · doi:10.1007/8904_2018_102 · Cited by 20
Wilson, R. J., Drake, J. C., Cui, D., Ritger, M. L., Guan, Y., Call, J. A., Zhang, M., Leitner, L. M., Gödecke, A., & Yan, Z. (2018) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00358.2018 · Cited by 20
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Wang, R., Cai, Y., Li, J., Yau, S., Lu, W., Stubbs, B., Su, K., Xu, G., So, K., Lin, K., et al. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.06.025 · Cited by 21
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Guo, M., Shen, F., Guo, X., Zhang, J., Ma, Y., Wu, X., Zuo, H., Yao, J., Hu, Y., Wang, D., et al. (2024) · Journal of sport and health science/Journal of Sport and Health Science · doi:10.1016/j.jshs.2024.100968 · Cited by 21
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Skelly, L. E., Bailleul, C., & Gillen, J. B. (2021) · Sports Medicine - Open · doi:10.1186/s40798-021-00390-y · Cited by 20
Theall, B. M., Stampley, J., Cho, E., Granger, J., Johannsen, N. M., Irving, B. A., & Spielmann, G. (2021) · Physiological Reports · doi:10.14814/phy2.15147 · Cited by 19
Is There Any Non-functional Training? A Conceptual Review
Ide, B. N., Silvatti, A. P., Marocolo, M., dos Santos, C. P. C., da Silva, B. V. C., Oranchuk, D. J., & da Mota, G. R. (2022) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2021.803366 · Cited by 19
Aerobic exercise ameliorates insulin resistance in C57BL/6 J mice via activating Sestrin3
Han, X., Yang, Y., Liu, S., Niu, Y., Shao, H., & Fu, L. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2022.166568 · Cited by 19
Protein Turnover in Skeletal Muscle: Looking at Molecular Regulation towards an Active Lifestyle
Ferreira, R. P., & Duarte, J. A. (2023) · International Journal of Sports Medicine · doi:10.1055/a-2044-8277 · Cited by 23
Davids, C. J., Roberts, L. A., Bjørnsen, T., Peake, J. M., Coombes, J. S., & Raastad, T. (2023) · Sports Medicine · doi:10.1007/s40279-023-01900-6 · Cited by 19
Delp, M., Chesbro, G. A., Pribble, B. A., Miller, R. M., Pereira, H. M., Black, C. D., & Larson, R. D. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2023.1297242 · Cited by 19
Acute vs. chronic hypoxia: What are the consequences for skeletal muscle mass?
Deldicque, L., & Francaux, M. (2013) · doi:10.7457/cmep.v2i1 · Cited by 19
Calf raise exercise increases walking performance in patients with intermittent claudication
van Schaardenburgh, M., Wohlwend, M., Rognmo, Ø., & Mattsson, E. J. R. (2017) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2016.12.106 · Cited by 19
Miš, K., Grubič, Z., Lorenzon, P., Sciancalepore, M., Marš, T., & Pirkmajer, S. (2017) · Molecules · doi:10.3390/molecules22091418 · Cited by 19
Svensson, K., Dent, J. R., Tahvilian, S., Martins, V. F., Sathe, A., Ochala, J., Patel, M. S., & Schenk, S. (2018) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00241.2018 · Cited by 18
Knee Extensors Muscle Plasticity Over a 5-Years Rehabilitation Process After Open Knee Surgery
Flück, M., Viecelli, C., Bapst, A. M., Kasper, S., Valdivieso, P., Franchi, M. V., Ruoss, S., Lüthi, J.-M., Bühler, M., Claassen, H., et al. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01343 · Cited by 19
High‐intensity interval training slows down tumor progression in mice bearing Lewis lung carcinoma
Alves, C. R. R., das Neves, W., Tobias, G. C., de Almeida, N. R., Barreto, R. F. D. P., de Melo, C. M., Carneiro, C. D. G., Garcez, A. T., Faria, D. D. P., Chammas, R. J., et al. (2018) · JCSM Rapid Communications · doi:10.1002/j.2617-1619.2018.tb00008.x · Cited by 21
Kim, Y. H., Jung, J. I., Jeon, Y. E., Kim, S. M., Oh, T. K., Lee, J., Moon, J. M., Kim, T. Y., & Kim, E. J. (2022) · Nutrition Research and Practice · doi:10.4162/nrp.2022.16.1.14 · Cited by 18
McCarthy, O. M., Moser, O., Eckstein, M. L., Bain, S. C., Pitt, J. P., & Bracken, R. M. (2019) · Nutrients · doi:10.3390/nu11071571 · Cited by 19
Temporal dynamics of the multi-omic response to endurance exercise training across tissuesPreprint
MoTrPAC Study Group, Amar, D., Gay, N. R., Beltran, P. M. J., Adkins, J., Armenteros, J. J. A., Ashley, E. A., Ávila-Pacheco, J., Bae, D., Bararpour, N., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.09.21.508770 · Cited by 19
Physical exercise elicits UPRmt in the skeletal muscle: The role of c-Jun N-terminal kinase
Gaspar, R. S., Katashima, C. K., Crisol, B., Carneiro, F. S., Sampaio, I. H., Silveira, L. R., da Silva, A. S. R., Cintra, D. E., Pauli, J. R., & Ropelle, E. R. (2023) · Molecular Metabolism · doi:10.1016/j.molmet.2023.101816 · Cited by 20
Voltarelli, V. A., Amano, M. T., Tobias, G. C., Borges, G. S., da Paixão, A. O., Pereira, M. G., Câmara, N. O. S., Caldeira, W., Ribeiro, A. F., Le, O., et al. (2024) · iScience · doi:10.1016/j.isci.2024.110121 · Cited by 18
Sun, Y., Fu, Z., Liu, X., & Ma, Z. (2024) · Antioxidants · doi:10.3390/antiox13111357 · Cited by 18
Maqueda, M., Roca, E., Brotons, D., Soria, J. M., & Perera-Lluna, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180322 · Cited by 20
Coordinated regulation of skeletal muscle mass and metabolic plasticity during recovery from disuse
Kneppers, A. E. M., Leermakers, P. A., Pansters, N. A. M., Backx, E. M. P., Gosker, H. R., van Loon, L. J. C., Schols, A. M. W. J., LANGEN, R. C. J., & Verdijk, L. B. (2018) · The FASEB Journal · doi:10.1096/fj.201701403rrr · Cited by 19
Acosta‐Manzano, P., Leopold‐Posch, B., Simmons, D. S., Devlieger, R., Galjaard, S., Corcoy, R., Adelantado, J. M., Dunne, F., Harreiter, J., Kautzky‐Willer, A., et al. (2021) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.16945 · Cited by 18
Izquierdo, P. G., Calahorro, F., Thisainathan, T., Atkins, J. H., Haszczyn, J., Lewis, C., Tattersall, J. E. H., Green, A. C., Holden-Dye, L. M., & O'Connor, V. M. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.101466 · Cited by 20
Transient changes to metabolic homeostasis initiate mitochondrial adaptation to endurance exercise
Dent, J. R., Stocks, B., Campelj, D. G., & Philp, A. (2022) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2022.03.022 · Cited by 19
Rønnestad, B. R., Bjerkrheim, K. A., Hansen, J., & Mølmen, K. S. (2022) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2022.948127 · Cited by 19
Ng, S. Y., Mikhail, A. I., Mattina, S. R., Manta, A., Diffey, I. J., & Ljubicic, V. (2023) · The FASEB Journal · doi:10.1096/fj.202201846rr · Cited by 18
Brauwers, B., Machado, F. V. C., Beijers, R. J. H. C. G., Spruit, M. A., & Franssen, F. M. E. (2023) · Nutrients · doi:10.3390/nu15245136 · Cited by 19
Sabaratnam, R., Kristensen, J. M., Pedersen, A. J. T., Kruse, R., Handberg, A., Wojtaszewski, J. F. P., & Højlund, K. (2024) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae032 · Cited by 19
IGF1 promotes human myotube differentiation toward a mature metabolic and contractile phenotype
Dreher, S. I., Grubba, P., von Toerne, C., Moruzzi, A., Maurer, J. A., Goj, T., Birkenfeld, A. L., Peter, A., Loskill, P., Hauck, S. M., et al. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00654.2023 · Cited by 20
Harnessing Mitochondrial Stress for Health and Disease: Opportunities and Challenges
Sun, Y., Jin, L., Qin, Y., Ouyang, Z., Zhong, J., & Zeng, Y. (2024) · Biology · doi:10.3390/biology13060394 · Cited by 17
Gonzalez, A. M. (2016) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000001378 · Cited by 21
Gao, Y., Melin, M., Mäkäräinen, K., Rantalainen, T., Pesola, A. J., Laukkanen, A., Sääkslahti, A., & Finni, T. J. (2018) · PeerJ · doi:10.7717/peerj.5437 · Cited by 23
Metadata
- Authors
- Egan, B., & Zierath, J. R.
- Affiliations
- University College Dublin (IE)
- University of Copenhagen (DK)
- Corresponding author
- Zierath, Juleen R.
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2013-02
- Volume
- 17
- Issue
- 2
- Pages
- 162-184
- ISSN
- 1550-4131 (ISSN-L)
- OpenAlex
- W1995381409
- Semantic Scholar
- 735dcdabdb4efc5dec9569db8f5a316859b70bd6
- Cited by
- 2,084
- References
- 210
- Citations by year
- 2026: 157 · 2025: 168 · 2024: 162 · 2023: 190 · 2022: 209 · 2021: 204 · 2020: 198 · 2019: 189 · 2018: 151 · 2017: 145 · 2016: 122 · 2015: 103 · 2014: 63 · 2013: 21
- FWCI
- 9.69
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 369 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Cell Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Vetenskapsrådet
- University College Dublin
- Novo Nordisk Fonden
- Karolinska Institutet
- European Research Council
- Knut och Alice Wallenbergs Stiftelse
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Keywords
- exercise metabolism, skeletal muscle adaptation, exercise training, aerobic exercise, resistance training, acute exercise, metabolic remodeling, signaling pathways, transcriptional regulation, translational regulation, muscle strength, cardiorespiratory fitness, chronic disease prevention
- MeSH terms
- Adaptation, Physiological, Humans, Hypertrophy, Muscle Contraction, Signal Transduction, Exercise, Muscle, Skeletal
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