Evolution of Mitochondria as Signaling Organelles

ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis

D'Autréaux, B., & Toledano, M. B. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2256 · Cited by 3,642 · see citing works

Mechanisms of mitophagy

Youle, R. J., & Narendra, D. P. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3028 · Cited by 3,273 · see citing works

Physiological Roles of Mitochondrial Reactive Oxygen Species

Sena, L. A., & Chandel, N. S. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.09.025 · Cited by 2,632 · see citing works

Mitochondrial DNA stress primes the antiviral innate immune response

West, A. P., Khoury-Hanold, W., Staron, M., Tal, M. C., Pineda, C. M., Lang, S. M., Bestwick, M., Duguay, B. A., Raimundo, N., MacDuff, D. A., et al. (2015) · Nature · doi:10.1038/nature14156 · Cited by 1,975 · see citing works

The Hydrogen Hypothesis for the First Eukaryote

Martin, W., & Müller, M. (1998) · Nature · doi:10.1038/32096 · Cited by 1,282 · see citing works

Acetyl-CoA and the regulation of metabolism: mechanisms and consequences

Shi, L., & Tu, B. P. (2015) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2015.02.003 · Cited by 903 · see citing works

Mitochondrial Evolution

Gray, M. W. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a011403 · Cited by 639 · see citing works

Mitohormesis

Yun, J., & Finkel, T. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.01.011 · Cited by 626 · see citing works

A two-way street: reciprocal regulation of metabolism and signalling

Wellen, K. E., & Thompson, C. B. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3305 · Cited by 528 · see citing works

Mitochondrial Dysfunction Leads to Nuclear Genome Instability via an Iron-Sulfur Cluster Defect

Veatch, J. R., McMurray, M. A., Nelson, Z. W., & Gottschling, D. E. (2009) · Cell · doi:10.1016/j.cell.2009.04.014 · Cited by 427 · see citing works

Determinants and Functions of Mitochondrial Behavior

Labbè, K., Murley, A., & Nunnari, J. M. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-101011-155756 · Cited by 315 · see citing works

Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond

Haynes, C. M., Fiorese, C. J., & Lin, Y. (2013) · Trends in Cell Biology · doi:10.1016/j.tcb.2013.02.002 · Cited by 209 · see citing works

Hallmarks of a new era in mitochondrial biochemistryPreprint

Pagliarini, D. J., & Rutter, J. P. (2013) · Genes & Development · doi:10.1101/gad.229724.113 · Cited by 177 · see citing works

The Mitochondrial Calcium Uniporter (MCU): Molecular Identity and Physiological Roles

Patrón, M., Raffaello, A., Granatiero, V., Tosatto, A., Merli, G., Stefani, D. D., Wright, L. E., Pallafacchina, G., Terrin, A., Mammucari, C., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.r112.420752 · Cited by 168 · see citing works

Production of superoxide anions in Paracoccus denitrificans

Henry, M.-F., & Vignais, P. M. (1980) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(80)90188-5 · Cited by 23 · see citing works

Mitochondrial TCA cycle metabolites control physiology and disease

Martínez-Reyes, I., & Chandel, N. S. (2020) · Nature Communications · doi:10.1038/s41467-019-13668-3 · Cited by 2,813 · see citing works

The cell biology of mitochondrial membrane dynamics

Giacomello, M., Pyakurel, A., Glytsou, C., & Scorrano, L. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-0210-7 · Cited by 1,550 · see citing works

Mitochondrial and metabolic dysfunction in ageing and age-related diseases

Amorim, J. A., Coppotelli, G., Rolo, A. P., Palmeira, C. M., Ross, J. M., & Sinclair, D. A. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00626-7 · Cited by 990 · see citing works

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

Quirós, P. M., Prado, M. A., Zamboni, N., D’Amico, D., Williams, R. W., Finley, D., Gygi, S. P., & Auwerx, J. (2017) · Journal of Cell Biology · doi:10.1083/jcb.201702058 · Cited by 832 · see citing works

AMPK maintains cellular metabolic homeostasis through regulation of mitochondrial reactive oxygen species

Rabinovitch, R. C., Samborska, B., Faubert, B., Ma, E. H., Gravel, S.-P., Andrzejewski, S., Raissi, T. C., Pause, A., St.-Pierre, J., & Jones, R. G. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.09.026 · Cited by 543 · see citing works

Mitochondrial ROS regulation of proliferating cells

Diebold, L., & Chandel, N. S. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.04.198 · Cited by 391 · see citing works

ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis

Kim, Y.-M., Kim, S.-J., Tatsunami, R., Yamamura, H., Fukai, T., & Ushio-Fukai, M. (2017) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00346.2016 · Cited by 251 · see citing works

Mitochondrial dysfunction and damage associated molecular patterns (DAMPs) in chronic inflammatory diseases

Dela Cruz, C. S., & Kang, M.-J. (2018) · Mitochondrion · doi:10.1016/j.mito.2017.12.001 · Cited by 255 · see citing works

Mitochondrial protein synthesis adapts to influx of nuclear-encoded protein

Richter-Dennerlein, R., Oeljeklaus, S., Lorenzi, I., Ronsör, C., Bareth, B., Schendzielorz, A. B., Wang, C., Warscheid, B., Rehling, P., & Dennerlein, S. (2016) · Cell · doi:10.1016/j.cell.2016.09.003 · Cited by 232 · see citing works

MOTS-c: a novel mitochondrial-derived peptide regulating muscle and fat metabolism

Lee, C., Kim, K. H., & Cohen, P. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.05.015 · Cited by 178 · see citing works

Structural basis and regulation of the reductive stress response

Manford, A. G., Mena, E. L., Shih, K. Y., Gee, C. L., McMinimy, R., Martínez-González, B., Sherriff, R., Lew, B., Zoltek, M., Rodríguez-Pérez, F., et al. (2021) · Cell · doi:10.1016/j.cell.2021.09.002 · Cited by 152 · see citing works

Mitochondrial Nanotunnels

Vincent, A. E., Turnbull, D. M., Eisner, V., Hajnóczky, G., & Picard, M. (2017) · Trends in Cell Biology · doi:10.1016/j.tcb.2017.08.009 · Cited by 135 · see citing works

High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions

Little, A. C., Kovalenko, I., Goo, L. E., Hong, H. S., Kerk, S. A., Yates, J. A., Purohit, V., Lombard, D. B., Merajver, S. D., & Lyssiotis, C. A. (2020) · Communications Biology · doi:10.1038/s42003-020-0988-z · Cited by 88 · see citing works

Mitochondrial stress-dependent regulation of cellular protein synthesis

Topf, U., Uszczynska-Ratajczak, B., & Chacinska, A. (2019) · Journal of Cell Science · doi:10.1242/jcs.226258 · Cited by 52 · see citing works

Increased Expression of the Mitochondrial Derived Peptide, MOTS-c, in Skeletal Muscle of Healthy Aging Men Is Associated with Myofiber Composition

D’Souza, R. F., Woodhead, J. S. T., Hedges, C. P., Zeng, N., Wan, J., Kumagai, H., Lee, C., Cohen, P., Cameron-Smith, D., Mitchell, C. J., et al. (2020) · Aging · doi:10.18632/aging.102944 · Cited by 55 · see citing works

Decoding the Rosetta stone of mitonuclear communication

English, J., Son, J. M., Cardamone, M. D., Lee, C., & Perissi, V. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105161 · Cited by 55 · see citing works

Modelling of dysregulated glucagon secretion in type 2 diabetes by considering mitochondrial alterations in pancreatic α-cells

Grubelnik, V., Markovič, R., Lipovšek, S., Leitinger, G., Gosak, M., Dolenšek, J., Valladolid-Acebes, I., Berggren, P.-O., Stožer, A., Perc, M., et al. (2020) · Royal Society Open Science · doi:10.1098/rsos.191171 · Cited by 32 · see citing works

SDH Subunit C Regulates Muscle Oxygen Consumption and Fatigability in an Animal Model of Pulmonary Emphysema

Balnis, J., Drake, L. A., Vincent, C. E., Korponay, T. C., Singer, D. V., Lacomis, D., Lee, C. G., Elias, J. A., Jourd’heuil, D., Singer, H. A., et al. (2021) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2020-0551oc · Cited by 19 · see citing works

Modelling of energy-driven switch for glucagon and insulin secretion

Grubelnik, V., Zmazek, J., Markovič, R., Gosak, M., & Marhl, M. (2020) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2020.110213 · Cited by 15 · see citing works

Schizosaccharomyces pombe Ppr10 and mpa1 together mediate mitochondrial translational initiation

Luo, Y., Wang, Y., & Huang, Y. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100869 · Cited by 10 · see citing works

Selective Determination of the Doxorubicin Content of Individual Acidic Organelles in Impure Subcellular Fractions

Chen, Y., Walsh, R. J., & Arriaga, E. A. (2005) · Analytical Chemistry · doi:10.1021/ac0480996 · Cited by 35 · see citing works

What’s Eating Eu? The Role of Eukaryote/Eukaryote Endosymbioses in Plastid Origins

McFadden, G. I., & Gilson, P. R. (1997) · Springer eBooks · doi:10.1007/978-3-642-60885-8_2 · Cited by 8 · see citing works

Endosymbiotic theories for eukaryote origin

Martin, W. F., Garg, S., & Zimorski, V. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2014.0330 · Cited by 583 · see citing works

Simultaneous isolation of intact mitochondria and chloroplasts from a single pulping of plant tissue

Rödiger, A., Baudisch, B., & Klösgen, R. B. (2010) · Journal of Plant Physiology · doi:10.1016/j.jplph.2009.11.013 · Cited by 52 · see citing works

Three-card trick

SILVERTOWN, J. W. (2024) · doi:10.1093/oso/9780198876397.003.0010