Pattern recognition receptors in the immune response against dying cells

Pathogen Recognition and Innate Immunity

Akira, S., Uematsu, S., & Takeuchi, O. (2006) · Cell · doi:10.1016/j.cell.2006.02.015 · Cited by 11,974 · see citing works

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Scaffidi, P., Misteli, T., & Bianchi, M. E. (2002) · Nature · doi:10.1038/nature00858 · Cited by 4,221 · see citing works

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

Wright, S. D., Ramos, R., Tobias, P. S., Ulevitch, R. J., & Mathison, J. C. (1990) · Science · doi:10.1126/science.1698311 · Cited by 3,986 · see citing works

Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Apetoh, L., Ghiringhelli, F., Tesniere, A., Obeid, M., Ortiz, C., Criollo, A., Mignot, G., Maiuri, M. C., Ullrich, E., Saulnier, P., et al. (2007) · Nature Medicine · doi:10.1038/nm1622 · Cited by 3,056 · see citing works

Recognition of microorganisms and activation of the immune response

Medzhitov, R. (2007) · Nature · doi:10.1038/nature06246 · Cited by 2,862 · see citing works

DAMPs, PAMPs and alarmins: all we need to know about danger

Bianchi, M. E. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0306164 · Cited by 2,794 · see citing works

TLR signaling

Kawai, T., & Akira, S. (2006) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401850 · Cited by 1,817 · see citing works

How dying cells alert the immune system to danger

Kono, H., & Rock, K. L. (2008) · Nature Reviews Immunology · doi:10.1038/nri2215 · Cited by 1,737 · see citing works

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.

Casciola-Rosen, L. A., Anhalt, G. J., & Rosen, A. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.179.4.1317 · Cited by 1,723 · see citing works

A blast from the past: clearance of apoptotic cells regulates immune responses

Savill, J., Dransfield, I., Gregory, C. D., & Haslett, C. (2002) · Nature reviews. Immunology · doi:10.1038/nri957 · Cited by 1,574 · see citing works

Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein

Park, J. S., Svetkauskaite, D., He, Q., Kim, J., Strassheim, D., Ishizaka, A., & Abraham, E. H. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m306793200 · Cited by 1,560 · see citing works

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

Botto, M., Dell' Agnola, C., Bygrave, A. E., Thompson, E. M., Cook, H. T., Petry, F., Loos, M., Pandolfi, P. P., & Walport, M. J. (1998) · Nature Genetics · doi:10.1038/ng0598-56 · Cited by 1,434 · see citing works

Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

Tian, J., Avalos, A. M., Mao, S.-Y., Chen, B., Senthil, K., Wu, H., Parroche, P., Drabic, S., Golenbock, D., Sirois, C., et al. (2007) · Nature Immunology · doi:10.1038/ni1457 · Cited by 1,372 · see citing works

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I

Coleman, M. L., Sahai, E. A., Yeo, M., Bosch, M., Dewar, A. L., & Olson, M. F. (2001) · Nature Cell Biology · doi:10.1038/35070009 · Cited by 1,313 · see citing works

Immature Dendritic Cells Phagocytose Apoptotic Cells via αvβ5 and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes

Albert, M. L., Pearce, S. F. A., Francisco, L. M., Sauter, B., Roy, P., Silverstein, R. L., & Bhardwaj, N. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.7.1359 · Cited by 1,234 · see citing works

Intracellular pattern recognition receptors in the host response

Meylan, E., Tschopp, J., & Karin, M. (2006) · Nature · doi:10.1038/nature04946 · Cited by 1,196 · see citing works

Pattern Recognition Receptors

Gordon, S. (2002) · Cell · doi:10.1016/s0092-8674(02)01201-1 · Cited by 1,153 · see citing works

C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells

Ogden, C. A., deCathelineau, A. M., Hoffmann, P. R., Bratton, D. L., Ghebrehiwet, B., Fadok, V. A., & Henson, P. M. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.6.781 · Cited by 1,148 · see citing works

The Inflammatory Response to Cell Death

Rock, K. L., & Kono, H. (2007) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev.pathmechdis.3.121806.151456 · Cited by 945 · see citing works

Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility.

Garlanda, C., Bottazzi, B., Bastone, A., & Mantovani, A. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115756 · Cited by 885 · see citing works

Toll-dependent selection of microbial antigens for presentation by dendritic cells

Blander, J. M., & Medzhitov, R. M. (2006) · Nature · doi:10.1038/nature04596 · Cited by 841 · see citing works

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis.

Savill, J., Hogg, N., Ren, Y., & Haslett, C. (1992) · Journal of Clinical Investigation · doi:10.1172/jci116019 · Cited by 813 · see citing works

Collectins and Ficolins: Humoral Lectins of the Innate Immune Defense

Holmskov, U., Thiel, S., & Jensenius, J. C. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.140954 · Cited by 762 · see citing works

C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response

Gershov, D., Kim, S., Brot, N., & Elkon, K. B. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.9.1353 · Cited by 695 · see citing works

Human CD14 mediates recognition and phagocytosis of apoptotic cells

Devitt, A., Moffatt, O., Raykundalia, C., Capra, J. D., Simmons, D. L., & Gregory, C. D. (1998) · Nature · doi:10.1038/33169 · Cited by 681 · see citing works

Engulfment of apoptotic cells: signals for a good meal

Ravichandran, K. S., & Lorenz, U. M. (2007) · Nature reviews. Immunology · doi:10.1038/nri2214 · Cited by 634 · see citing works

HMGB1 is an endogenous immune adjuvant released by necrotic cells

Rovere, P. Q., Capobianco, A., Scaffidi, P., Valentinis, B., Catalanotti, F., Giazzon, M., Dumitriu, I. E., Müller, S., Iannacone, M., Traversari, C., et al. (2004) · EMBO Reports · doi:10.1038/sj.embor.7400205 · Cited by 591 · see citing works

MDA5/RIG-I and virus recognition

Takeuchi, O., & Akira, S. (2008) · Current Opinion in Immunology · doi:10.1016/j.coi.2008.01.002 · Cited by 567 · see citing works

Role of Surfactant Proteins A, D, and C1q in the Clearance of Apoptotic Cells In Vivo and In Vitro: Calreticulin and CD91 as a Common Collectin Receptor Complex

Vandivier, R. W., Ogden, C. A., Fadok, V. A., Hoffmann, P. R., Brown, K. K., Botto, M., Walport, M. J., Fisher, J. H., Henson, P. M., & Greene, K. E. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.7.3978 · Cited by 517 · see citing works

C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids

Chang, M.-K., Binder, C. J., Torzewski, M., & Witztum, J. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.192399699 · Cited by 517 · see citing works

Myeloid C-type lectins in innate immunity

Robinson, M. J., Sancho, D., Slack, E. M. C., LeibundGut‐Landmann, S., & Sousa, C. R. E. (2006) · Nature Immunology · doi:10.1038/ni1417 · Cited by 511 · see citing works

A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA

Ivanov, S. S., Dragoi, A., Wang, X., Dallacosta, C., Louten, J., Musco, G., Sitia, G., Yap, G. S., Wan, Y., Biron, C. A., et al. (2007) · Blood · doi:10.1182/blood-2006-09-044776 · Cited by 472 · see citing works

Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor

Park, S.-Y., Jung, M.-Y., Kim, H.-J., Lee, S., Kim, S.-Y., Lee, B.-H., Kwon, T.-H., Park, R. W., & Kim, I. T. (2007) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4402242 · Cited by 464 · see citing works

Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: Evidence that oxidation-specific epitopes mediate macrophage recognition

Chang, M.-K., Bergmark, C., Laurila, A., Hörkkö, S., Han, K., Friedman, P., Dennis, E. A., & Witztum, J. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.11.6353 · Cited by 456 · see citing works

Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro.

Platt, N., Suzuki, H., Kurihara, Y., Kodama, T., & Gordon, S. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.22.12456 · Cited by 428 · see citing works

Clearance of apoptotic cells by phagocytes

Erwig, L.-P., & Henson, P. M. (2008) · Cell Death & Differentiation · doi:10.1038/sj.cdd.4402184 · Cited by 422 · see citing works

CD36 gene transfer confers capacity for phagocytosis of cells undergoing apoptosis.

Ren, Y., Silverstein, R. L., Allen, J., & Savill, J. (1995) · The Journal of Experimental Medicine · doi:10.1084/jem.181.5.1857 · Cited by 389 · see citing works

Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells

Oka, K., Sawamura, T., Kikuta, K., Itokawa, S., Kume, N., Kita, T., & Masaki, Τ. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.16.9535 · Cited by 383 · see citing works

Differential Effects of Apoptotic Versus Lysed Cells on Macrophage Production of Cytokines: Role of Proteases

Fadok, V. A., Bratton, D. L., Guthrie, L. A., & Henson, P. M. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.11.6847 · Cited by 368 · see citing works

Bystander apoptosis triggers dendritic cell maturation and antigen-presenting function.

Rovere, P. Q., Vallinoto, C., Bondanza, A., Crosti, M., Rescigno, M., Ricciardi‐Castagnoli, P., Rugarli, C., & Manfredi, A. A. (1998) · PubMed · Cited by 352 · see citing works

Biochemical and functional characterization of the interaction between pentraxin 3 and C1q

Nauta, A. J., Bottazzi, B., Mantovani, A., Salvatori, G., Kishore, U., Schwaeble, W., Gingras, A. R., Tzima, S., Vivanco, F., Egido, J., et al. (2003) · European Journal of Immunology · doi:10.1002/immu.200310022 · Cited by 348 · see citing works

Biochemistry and cell biology of mammalian scavenger receptors

Murphy, J. E., Tedbury, P. R., Homer‐Vanniasinkam, S., Walker, J. H., & Ponnambalam, S. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.03.036 · Cited by 331 · see citing works

The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells

Rovere, P. Q., Peri, G., Fazzini, F., Bottazzi, B., Doni, A., Bondanza, A., Zimmermann, V. S., Garlanda, C., Fascio, U., Sabbadini, M. G., et al. (2000) · Blood · doi:10.1182/blood.v96.13.4300 · Cited by 326 · see citing works

Characterization of CLA-1, a Human Homologue of Rodent Scavenger Receptor BI, as a Receptor for High Density Lipoprotein and Apoptotic Thymocytes

Murao, K., Terpstra, V., Green, S. R., Kondratenko, N., Steinberg, D. H., & Quehenberger, O. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.28.17551 · Cited by 322 · see citing works

Mannose‐binding lectin engagement with late apoptotic and necrotic cells

Nauta, A. J., Raaschou‐Jensen, N., Roos, A., Daha, M. R., MADSEN, H. O., Borrias, M. C., Ryder, L. P., Koch, C., & Garred, P. (2003) · European Journal of Immunology · doi:10.1002/eji.200323888 · Cited by 322 · see citing works

Clearance of apoptotic and necrotic cells and its immunological consequences

Krysko, D. V., D’Herde, K., & Vandenabeele, P. (2006) · Apoptosis · doi:10.1007/s10495-006-9527-8 · Cited by 316 · see citing works

The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68.

Ramprasad, M. P., Fischer, W., Witztum, J. L., Sambrano, G. R., Quehenberger, O., & Steinberg, D. H. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.21.9580 · Cited by 311 · see citing works

Cutting Edge: Bystander Apoptosis Triggers Dendritic Cell Maturation and Antigen-Presenting Function

Rovere, P. Q., Vallinoto, C., Bondanza, A., Crosti, M., Rescigno, M., Ricciardi‐Castagnoli, P., Rugarli, C., & Manfredi, A. A. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.9.4467 · Cited by 309 · see citing works

High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF-α Production in Human Monocytes

Youn, J. H., Oh, Y. J., Kim, E. S., Choi, J. E., & Shin, J.-S. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.7.5067 · Cited by 281 · see citing works

C1q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition

Païdassi, H., Tacnet‐Delorme, P., Garlatti, V., Darnault, C., Ghebrehiwet, B., Gaboriaud, C., Arlaud, G. J., & Frachet, P. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.4.2329 · Cited by 270 · see citing works

Nucleosomes Are Exposed at the Cell Surface in Apoptosis

Radic, M. Z., Marion, T. N., & Monestier, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.11.6692 · Cited by 218 · see citing works

Mannose-Binding Lectin-Deficient Mice Display Defective Apoptotic Cell Clearance but No Autoimmune Phenotype

Stuart, L. M., Takahashi, K., Shi, L., Savill, J., & Ezekowitz, R. A. B. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.6.3220 · Cited by 205 · see citing works

Macrophage Recognition of ICAM-3 on Apoptotic Leukocytes

Moffatt, O., Devitt, A., Bell, E. D., Simmons, D. L., & Gregory, C. D. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.11.6800 · Cited by 185 · see citing works

Oxidized Phospholipids as Endogenous Pattern Recognition Ligands in Innate Immunity

Hazen, S. L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.r700054200 · Cited by 176 · see citing works

The mannose-binding lectin: a prototypic pattern recognition molecule

Takahashi, K., Ip, W. E., Michelow, I. C., & Ezekowitz, R. A. B. (2005) · Current Opinion in Immunology · doi:10.1016/j.coi.2005.11.014 · Cited by 174 · see citing works

Nucleic Acid Is a Novel Ligand for Innate, Immune Pattern Recognition Collectins Surfactant Proteins A and D and Mannose-binding Lectin

Palaniyar, N., Nadesalingam, J., Clark, H. W., Shih, M. J., Dodds, A. W., & Reid, K. B. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403763200 · Cited by 161 · see citing works

Recognition of oxidatively damaged erythrocytes by a macrophage receptor with specificity for oxidized low density lipoprotein.

Sambrano, G. R., Parthasarathy, S., & Steinberg, D. H. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.8.3265 · Cited by 154 · see citing works

Apoptotic Cells Protect Mice against Lipopolysaccharide-Induced Shock

Ren, Y., Xie, Y., Jiang, G., B, J. F. A., Yeung, J. S. L., Li, W., Tam, P. K. H., & Savill, J. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.7.4978 · Cited by 150 · see citing works

Ficolin-2 recognizes DNA and participates in the clearance of dying host cells

Jensen, M. L., Honoré, C., Hummelshøj, T., Hansen, B. E., MADSEN, H. O., & Garred, P. (2006) · Molecular Immunology · doi:10.1016/j.molimm.2006.04.002 · Cited by 148 · see citing works

Antineutrophil Cytoplasmic Autoantibodies Interact with Primary Granule Constituents on the Surface of Apoptotic Neutrophils in the Absence of Neutrophil Priming

Gilligan, H. M., Bredy, B., Brady, H. R., Hébert, M., Slayter, H. S., Xu, Y., Rauch, J., Shia, M. A., Koh, J. S., & Levine, J. S. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.184.6.2231 · Cited by 146 · see citing works

Persistence of apoptotic cells without autoimmune disease or inflammation in CD14−/− mice

Devitt, A., Parker, K. G., Ogden, C. A., Oldreive, C., Clay, M. F., Melville, L. A., Bellamy, C. O. C., Lacy‐Hulbert, A., Gangloff, S. C., Goyert, S. M., et al. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200410057 · Cited by 135 · see citing works

The tissue pentraxin PTX3 limits C1q-mediated complement activation and phagocytosis of apoptotic cells by dendritic cells

Baruah, P., Dumitriu, I. E., Peri, G., Russo, V. E. A., Mantovani, A., Manfredi, A. A., & Rovere, P. Q. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.0805445 · Cited by 132 · see citing works

The innate immune component ficolin 3 (Hakata antigen) mediates the clearance of late apoptotic cells

Honoré, C., Hummelshøj, T., Hansen, B. E., MADSEN, H. O., Eggleton, P., & Garred, P. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22564 · Cited by 121 · see citing works

Collectins: sentinels of innate immunity

Gupta, G., & Surolia, A. (2007) · BioEssays · doi:10.1002/bies.20573 · Cited by 112 · see citing works

Apoptotic cell thrombospondin-1 and heparin-binding domain lead to dendritic-cell phagocytic and tolerizing states

Krispin, A., Bledi, Y., Atallah, M., Trahtemberg, U., Verbovetski, I., Nahari, E., Zelig, O., Michal Linial, B., & Mevorach, D. (2006) · Blood · doi:10.1182/blood-2006-03-013334 · Cited by 108 · see citing works

Delayed lupus onset in (NZB × NZW)F1 mice expressing a human C‐reactive protein transgene

Szalai, A. J., Weaver, C. T., McCrory, M. A., van Ginkel, F. W., Reiman, R. M., Kearney, J. F., Marion, T. N., & Volanakis, J. E. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11026 · Cited by 100 · see citing works

Apoptotic Cell Recognition: Will the Real Phosphatidylserine Receptor(s) Please Stand up?

Bratton, D. L., & Henson, P. M. (2008) · Current Biology · doi:10.1016/j.cub.2007.11.024 · Cited by 99 · see citing works

After shrinkage apoptotic cells expose internal membrane-derived epitopes on their plasma membranes

Franz, S., Herrmann, K., Führnrohr, B. G., Sheriff, A., Frey, B., Gaipl, U. S., Voll, R. E., Kalden, J. R., Jäck, H., & i, M. H. (2006) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4402066 · Cited by 89 · see citing works

The prototypic tissue pentraxin PTX3, in contrast to the short pentraxin serum amyloid P, inhibits phagocytosis of late apoptotic neutrophils by macrophages

van Rossum, A. P., Fazzini, F., Limburg, P. C., Manfredi, A. A., Rovere, P. Q., Mantovani, A., & Kallenberg, C. G. M. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20370 · Cited by 89 · see citing works

Genetic variation in the CRP promoter: association with systemic lupus erythematosus

Edberg, J. C., Wu, J., Langefeld, C. D., Brown, E. E., Marion, M. C., McGwin, G., Petri, M., Ramsey‐Goldman, R., Reveille, J. D., Frank-Pearce, S. G., et al. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn004 · Cited by 65 · see citing works

Innate Immune Collectin Surfactant Protein D Enhances the Clearance of DNA by Macrophages and Minimizes Anti-DNA Antibody Generation

Palaniyar, N., Clark, H. W., Nadesalingam, J., Shih, M. J., Hawgood, S. B., & Reid, K. B. M. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.11.7352 · Cited by 59 · see citing works

New Phosphatidylserine Receptors: Clearance of Apoptotic Cells and More

Zhou, Z. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.11.009 · Cited by 55 · see citing works

Competitive binding of pentraxins and IgM to newly exposed epitopes on late apoptotic cells

Ciurana, C. L. F., & Hack, C. E. (2006) · Cellular Immunology · doi:10.1016/j.cellimm.2006.02.006 · Cited by 25 · see citing works

A Must-Read

Lubinski, D. (1995) · Contemporary Psychology · doi:10.1037/004037 · Cited by 17 · see citing works

Neutrophils in the activation and regulation of innate and adaptive immunity

Mantovani, A., Cassatella, M. A., Costantini, C., & Jaillon, S. (2011) · Nature reviews. Immunology · doi:10.1038/nri3024 · Cited by 3,045 · see citing works

The Neutrophil's Role During Health and Disease.

Liew, P., & Kubes, P. (2019) · Physiological Reviews · doi:10.1152/physrev.00012.2018 · Cited by 1,032 · see citing works

Immunogenic and tolerogenic cell death

Green, D. R., Ferguson, T., Zitvogel, L., & Kroemer, G. (2009) · Nature Reviews Immunology · doi:10.1038/nri2545 · Cited by 1,176 · see citing works

Sexual Dimorphism in Innate Immunity

Jaillon, S., Berthenet, K., & Garlanda, C. (2019) · Clinical reviews in allergy and immunology · doi:10.1007/s12016-017-8648-x · Cited by 659 · see citing works

Adiponectin Promotes Macrophage Polarization toward an Anti-inflammatory Phenotype

Ohashi, K., Parker, J. L., Ouchi, N., Higuchi, A., Vita, J. A., Gokce, N., Pedersen, A. A., Kalthoff, C., Tullin, S., Sams, A., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.088708 · Cited by 646 · see citing works

Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity

Jaeschke, H., Williams, C. D., Ramachandran, A., & Bajt, M. L. (2011) · Liver International · doi:10.1111/j.1478-3231.2011.02501.x · Cited by 478 · see citing works

Immune–neural connections: how the immune system’s response to infectious agents influences behavior

McCusker, R. H., & Kelley, K. W. (2013) · Journal of Experimental Biology · doi:10.1242/jeb.073411 · Cited by 429 · see citing works

DAMPs, MAMPs, and NAMPs in plant innate immunity

Choi, H. W., & Klessig, D. F. (2016) · BMC Plant Biology · doi:10.1186/s12870-016-0921-2 · Cited by 356 · see citing works

Reactive oxygen species (ROS) – a family of fate deciding molecules pivotal in constructive inflammation and wound healing

Bryan, N., Ahswin, H., Smart, N. J., Bayon, Y., Wohlert, S., & Hunt, J. A. (2012) · European Cells and Materials · doi:10.22203/ecm.v024a18 · Cited by 317 · see citing works

Mitochondrial gateways to cancer

Galluzzi, L., Morselli, E., Kepp, O., Vitale, I., Rigoni, A., Vacchelli, E., Michaud, M., Zischka, H., Castedo, M., & Kroemer, G. (2009) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2009.08.002 · Cited by 296 · see citing works

Neutrophils in innate and adaptive immunity

Jaillon, S., Galdiero, M. R., Prete, D. D., Cassatella, M. A., Garlanda, C., & Mantovani, A. (2013) · Seminars in Immunopathology · doi:10.1007/s00281-013-0374-8 · Cited by 284 · see citing works

Immunological Variation Between Inbred Laboratory Mouse Strains: Points to Consider in Phenotyping Genetically Immunomodified Mice

Sellers, R. S., Clifford, C. B., Treuting, P. M., & Brayton, C. (2012) · Veterinary Pathology · doi:10.1177/0300985811429314 · Cited by 278 · see citing works

MicroRNAs in Immune Response and Macrophage Polarization

Liu, G., & Abraham, E. H. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.300068 · Cited by 243 · see citing works

Chondrogenic progenitor cells respond to cartilage injury

Seol, D., Mccabe, D. J., Choe, H., Zheng, H., Yu, Y., Jang, K., Walter, M., Lehman, A. D., Ding, L., Buckwalter, J. A., et al. (2012) · Arthritis & Rheumatism · doi:10.1002/art.34613 · Cited by 234 · see citing works

Galectins and Immune Responses—Just How Do They Do Those Things They Do?

Thiemann, S., & Baum, L. G. (2016) · Annual Review of Immunology · doi:10.1146/annurev-immunol-041015-055402 · Cited by 232 · see citing works

The speed of change: towards a discontinuity theory of immunity?

Pradeu, T., Jaeger, S., & Vivier, É. (2013) · Nature reviews. Immunology · doi:10.1038/nri3521 · Cited by 200 · see citing works

Cancer and Innate Immune System Interactions

Liu, Y., & Zeng, G. (2012) · Journal of Immunotherapy · doi:10.1097/cji.0b013e3182518e83 · Cited by 185 · see citing works

The Monocarboxylate Transporter 4 Is Required for Glycolytic Reprogramming and Inflammatory Response in Macrophages

Tan, Z., Xie, N., Banerjee, S., Cui, H., Fu, M., Thannickal, V. J., & Liu, G. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.603589 · Cited by 186 · see citing works

Pentraxins in innate immunity: lessons from PTX3

Deban, L., Jaillon, S., Garlanda, C., Bottazzi, B., & Mantovani, A. (2010) · Cell and Tissue Research · doi:10.1007/s00441-010-1018-0 · Cited by 158 · see citing works

Inhibiting neuroinflammation: The role and therapeutic potential of GABA in neuro-immune interactions

Crowley, T., Cryan, J. F., Downer, E. J., & O’Leary, O. F. (2016) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2016.02.001 · Cited by 150 · see citing works

Therapeutically relevant aspects in bone repair and regeneration

Pérez, R. A., Seo, S.-J., Won, J., Lee, E., Jang, J.-H., Knowles, J. C., & Kim, H. (2015) · Materials Today · doi:10.1016/j.mattod.2015.06.011 · Cited by 135 · see citing works

Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses

Cunin, P., Beauvillain, C., Miot, C., Augusto, J., Preisser, L., Blanchard, S., Pignon, P., Scotet, M., Garo, E., Frémaux, I., et al. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.113 · Cited by 132 · see citing works

Selective Proinflammatory Activation of Astrocytes by High-Mobility Group Box 1 Protein Signaling

Pedrazzi, M., Patrone, M., Passalacqua, M., Ranzato, E., Colamassaro, D., Sparatore, B., Pontremoli, S., & Melloni, E. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.12.8525 · Cited by 132 · see citing works

Complement in removal of the dead – balancing inflammation

Martin, M., & Blom, A. M. (2016) · Immunological Reviews · doi:10.1111/imr.12462 · Cited by 130 · see citing works

miR-27a regulates inflammatory response of macrophages by targeting IL-10

Xie, N., Cui, H., Banerjee, S., Tan, Z., Salomao, R., Fu, M., Abraham, E., Thannickal, V. J., & Liu, G. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1400203 · Cited by 120 · see citing works

Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products

Jaeschke, H., Williams, C. D., McGill, M. R., Xie, Y., & Ramachandran, A. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.12.063 · Cited by 121 · see citing works

Helminths and dendritic cells: Sensing and regulating via pattern recognition receptors, Th2 and Treg responses

Everts, B., Smits, H. H., Hokke, C. H., & Yazdanbakhsh, M. (2010) · European Journal of Immunology · doi:10.1002/eji.200940109 · Cited by 119 · see citing works

eIF2α phosphorylation as a biomarker of immunogenic cell death

Kepp, O., Semeraro, M., Pedro, J. M. B., Bloy, N., Buqué, A., Huang, X., Zhou, H., Senovilla, L., Kroemer, G., & Galluzzi, L. (2015) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2015.02.004 · Cited by 115 · see citing works

Review: Soluble innate immune pattern-recognition proteins for clearing dying cells and cellular components: implications on exacerbating or resolving inflammation

Litvack, M. L., & Palaniyar, N. (2010) · Innate Immunity · doi:10.1177/1753425910369271 · Cited by 98 · see citing works

Innate immunity of finfish: Primordial conservation and function of viral RNA sensors in teleosts

Aoki, T., Hikima, J.-I., Hwang, S. D., & Jung, T. S. (2013) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2013.02.005 · Cited by 93 · see citing works

PTX3 as a paradigm for the interaction of pentraxins with the Complement system

Inforzato, A., Doni, A., Barajon, I., Leone, R., Garlanda, C., Bottazzi, B., & Mantovani, A. (2013) · Seminars in Immunology · doi:10.1016/j.smim.2013.05.002 · Cited by 91 · see citing works

Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signalling

Pupjalis, D., Goetsch, J., Kottas, D. J., Gerke, V., & Rescher, U. (2010) · EMBO Molecular Medicine · doi:10.1002/emmm.201000113 · Cited by 90 · see citing works

Adenovirus Activates Complement by Distinctly Different Mechanisms In Vitro and In Vivo: Indirect Complement Activation by Virions In Vivo

Tian, J., Xu, Z., Smith, J. S., Hofherr, S. E., Barry, M. A., & Byrnes, A. P. (2009) · Journal of Virology · doi:10.1128/jvi.00082-09 · Cited by 88 · see citing works

The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules

Mantovani, A., Valentino, S., Gentile, S., Inforzato, A., Bottazzi, B., & Garlanda, C. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12043 · Cited by 87 · see citing works

Insufficient TLR Activation Contributes to the Slow Development of CD8+ T Cell Responses in Trypanosoma cruzi Infection

Padilla, A. M., Simpson, L. J., & Tarleton, R. L. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901178 · Cited by 87 · see citing works

New Insights into the Role of Ficolins in the Lectin Pathway of Innate Immunity

Endo, Y., Matsushita, M., & Fujita, T. (2015) · International review of cytology · doi:10.1016/bs.ircmb.2015.01.003 · Cited by 85 · see citing works

Pathogen Recognition by the Long Pentraxin PTX3

Moalli, F., Jaillon, S., Inforzato, A., Sironi, M., Bottazzi, B., Mantovani, A., & Garlanda, C. (2011) · BioMed Research International · doi:10.1155/2011/830421 · Cited by 83 · see citing works

Cyclophosphamide Induces a Type I Interferon–Associated Sterile Inflammatory Response Signature in Cancer Patients' Blood Cells: Implications for Cancer Chemoimmunotherapy

Moschella, F., Torelli, G. F., Valentini, M., Urbani, F., Buccione, C., Petrucci, M. T., Natalino, F., Belardelli, F., Foà, R., & Proietti, E. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-12-3666 · Cited by 83 · see citing works

Endogenous PTX3 translocates at the membrane of late apoptotic human neutrophils and is involved in their engulfment by macrophages

Jaillon, S., Jeannin, P., Hamon, Y., Frémaux, I., Doni, A., Bottazzi, B., Blanchard, S., Subra, J., Chevailler, A., Mantovani, A., et al. (2008) · Cell Death and Differentiation · doi:10.1038/cdd.2008.173 · Cited by 82 · see citing works

Trends and advances in tumor immunology and lung cancer immunotherapy

Aldarouish, M., & Wang, C. (2016) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-016-0439-3 · Cited by 79 · see citing works

Signaling and Communication in Plants

Mugnai, S. (2011) · Frontiers in artificial intelligence and applications · doi:10.3233/978-1-60750-972-1-205 · Cited by 80 · see citing works

LOX-1 as a natural IFN-α–mediated signal for apoptotic cell uptake and antigen presentation in dendritic cells

Parlato, S., Romagnoli, G., Spadaro, F., Canini, I., Sirabella, P., Borghi, P., Ramoni, C., Filesi, I., Biocca, S., Gabriele, L., et al. (2009) · Blood · doi:10.1182/blood-2009-07-234468 · Cited by 79 · see citing works

Different Responsiveness of Endothelial Cells to Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Added to Culture Media Under Gravity and Simulated Microgravity

Grimm, D. G., Bauer, J. W., Ulbrich, C., Westphal, K., Wehland, M., Infanger, M., Aleshcheva, G., Pietsch, J., Ghardi, M., Beck, M., et al. (2009) · Tissue Engineering Part A · doi:10.1089/ten.tea.2009.0524 · Cited by 79 · see citing works

Interactions of the humoral pattern recognition molecule PTX3 with the complement system

Doni, A., Garlanda, C., Bottazzi, B., Meri, S., Garred, P., & Mantovani, A. (2012) · Immunobiology · doi:10.1016/j.imbio.2012.07.004 · Cited by 72 · see citing works

Extracorporeal photopheresis-induced immune tolerance: a focus on modulation of antigen-presenting cells and induction of regulatory T cells by apoptotic cells

Xia, C., Campbell, K. A., & Clare-Salzler, M. J. (2009) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0b013e32832ce943 · Cited by 66 · see citing works

The “sweet” side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

Inforzato, A., Reading, P. C., Barbati, E., Bottazzi, B., Garlanda, C., & Mantovani, A. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00407 · Cited by 65 · see citing works

The long pentraxin PTX 3: A prototypical sensor of tissue injury and a regulator of homeostasis

Erreni, M., Manfredi, A. A., Garlanda, C., Mantovani, A., & Rovere, P. Q. (2017) · Immunological Reviews · doi:10.1111/imr.12570 · Cited by 60 · see citing works

5-Lipoxygenase Deficiency Reduces Acetaminophen-Induced Hepatotoxicity and Lethality

Hohmann, M. S., Cardoso, R. D. R., Pinho-Ribeiro, F. A., Crespigio, J., Cunha, T. M., Alves-Filho, J. C., da Silva, R. V., Pinge‐Filho, P., Ferreira, S. H., Cunha, F. Q., et al. (2013) · BioMed Research International · doi:10.1155/2013/627046 · Cited by 59 · see citing works

Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis

Crowley, T., Fitzpatrick, J.-M., Kuijper, T., Cryan, J. F., O’Toole, O., O’Leary, O. F., & Downer, E. J. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00284 · Cited by 58 · see citing works

Endoplasmic Reticulum Chaperones and Oxidoreductases: Critical Regulators of Tumor Cell Survival and Immunorecognition

Gutiérrez, T., & Simmen, T. (2014) · Frontiers in Oncology · doi:10.3389/fonc.2014.00291 · Cited by 55 · see citing works

Pentraxins in Humoral Innate Immunity

Inforzato, A., Bottazzi, B., Garlanda, C., Valentino, S., & Mantovani, A. (2011) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-0106-3_1 · Cited by 56 · see citing works

Enhancing CNS Repair in Neurological Disease

Xu, X., Warrington, A. E., Bieber, A. J., & Rodriguez, M. (2011) · CNS Drugs · doi:10.2165/11587830-000000000-00000 · Cited by 56 · see citing works

The Long Pentraxin PTX3 as a Key Component of Humoral Innate Immunity and a Candidate Diagnostic for Inflammatory Diseases

Jaillon, S., Bonavita, E., Gentile, S., Rubino, M., Laface, I., Garlanda, C., & Mantovani, A. (2014) · International Archives of Allergy and Immunology · doi:10.1159/000368778 · Cited by 55 · see citing works

A novel scavenger receptor-cysteine-rich (SRCR) domain containing scavenger receptor identified from mollusk mediated PAMP recognition and binding

Liu, L., Yang, J., Qiu, L., Wang, L., Zhang, H., Wang, M., Siva, V. S., & Song, L. (2010) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2010.09.010 · Cited by 55 · see citing works

Cannabinoids and Innate Immunity: Taking a Toll on Neuroinflammation

Downer, E. J. (2011) · The Scientific World JOURNAL · doi:10.1100/tsw.2011.84 · Cited by 52 · see citing works

Mitochondrial Dysfunction and Inflammaging in Heart Failure: Novel Roles of CYP-Derived Epoxylipids

Keshavarz-Bahaghighat, H., Darwesh, A. M., Sosnowski, D. K., & Seubert, J. M. (2020) · Cells · doi:10.3390/cells9071565 · Cited by 49 · see citing works

The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells

Beauvillain, C., Meloni, F., Sirard, J., Blanchard, S., Jarry, U., Scotet, M., Magistrelli, G., Delneste, Y., Barnaba, V., & Jeannin, P. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2009.11.031 · Cited by 42 · see citing works

The Colon

Sellers, R. S., & Morton, D. G. (2013) · Toxicologic Pathology · doi:10.1177/0192623313505930 · Cited by 39 · see citing works

Fine-tuning of T cell responses during infection

Dorhoi, A., & Kaufmann, S. H. E. (2009) · Current Opinion in Immunology · doi:10.1016/j.coi.2009.07.004 · Cited by 39 · see citing works

Manipulation of the glycan‐specific natural antibody repertoire for immunotherapy

New, J. S., King, R. G., & Kearney, J. F. (2016) · Immunological Reviews · doi:10.1111/imr.12397 · Cited by 37 · see citing works

Incomplete clearance of apoptotic cells in systemic lupus erythematosus: pathogenic role and potential biomarker

Jung, J., & Suh, C. (2015) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.12568 · Cited by 36 · see citing works

ncRNA-regulated immune response and its role in inflammatory lung diseases

Xie, N., & Liu, G. (2015) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00286.2015 · Cited by 36 · see citing works

RNA-Seq analysis of immune-relevant genes in Lateolabrax japonicus during Vibrio anguillarum infection

Zhao, C., Fu, M., Wang, C., Jiao, Z., & Qiu, L. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.02.032 · Cited by 35 · see citing works

NLRX1 of black carp suppresses MAVS-mediated antiviral signaling through its NACHT domain

Song, X., Li, W., Xie, X., Zou, Z., Wei, J., Wu, H., & Feng, H. (2019) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2019.03.001 · Cited by 35 · see citing works

Characterization of the Toll-like Receptor Expression Profile in Human Multiple Myeloma Cells

Abdi, J., Mutis, T., Garssen, J., & Redegeld, F. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060671 · Cited by 35 · see citing works

Pattern Recognition by Melanoma Differentiation-Associated Gene 5 (Mda5) in Teleost Fish: A Review

Lazarte, J. M. S., Thompson, K. D., & Jung, T. S. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00906 · Cited by 34 · see citing works

Mast Cells in Lung Homeostasis: Beyond Type I Hypersensitivity

Campillo-Navarro, M., Chávez-Blanco, A. D., Wong‐Baeza, I., Serafín‐López, J., Flores-Mejía, R., Estrada-Parra, S. A., Estrada‐García, I., & Chacón‐Salinas, R. (2014) · Current Respiratory Medicine Reviews · doi:10.2174/1573398x10666141024220151 · Cited by 33 · see citing works

A review of advances in the understanding of lupus nephritis pathogenesis as a basis for emerging therapies

Yung, S., Yap, D. Y. H., & Chan, T. M. (2020) · F1000Research · doi:10.12688/f1000research.22438.1 · Cited by 32 · see citing works

Shaoyao-Gancao Decoction, a famous Chinese medicine formula, protects against APAP-induced liver injury by promoting autophagy/mitophagy

Wu, Y., Li, W., Zhang, J., Lin, J., You, L., Su, J., Zheng, C., Gao, Y., Kong, X., & Sun, X. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.156053 · Cited by 32 · see citing works

Prototypic Long Pentraxin PTX3 Is Present in Breast Milk, Spreads in Tissues, and Protects Neonate Mice from Pseudomonas aeruginosa Lung Infection

Jaillon, S., Mancuso, G., Hamon, Y., Beauvillain, C., Cotici, V., Midiri, A., Bottazzi, B., Nebuloni, M., Garlanda, C., Frémaux, I., et al. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1201642 · Cited by 32 · see citing works

Alternol triggers immunogenic cell death via reactive oxygen species generation

Li, C., Zhang, Y., Yan, S., Zhang, G., Wei, W., Qi, Z., & Li, B. (2021) · OncoImmunology · doi:10.1080/2162402x.2021.1952539 · Cited by 32 · see citing works

Mannose-Binding Lectin Blunts Macrophage Polarization and Ameliorates Lupus Nephritis

Cai, Y., Zhang, W., & Xiong, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062465 · Cited by 31 · see citing works

Anti‐Inflammatory Effect of a Polyphenol‐Enriched Fraction from Acalypha wilkesiana on Lipopolysaccharide‐Stimulated RAW 264.7 Macrophages and Acetaminophen‐Induced Liver Injury in Mice

Wu, H., Pang, H., Chen, Y.-P., Huang, L., Liu, H., Zheng, Y., Sun, C., Zhang, G., & Wang, G. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/7858094 · Cited by 31 · see citing works

Clam focal and systemic immune responses to QPX infection revealed by RNA-seq technology

Wang, K., del Castillo, C. S., Corre, E., Espinosa, E. P., & Allam, B. (2016) · BMC Genomics · doi:10.1186/s12864-016-2493-9 · Cited by 30 · see citing works

Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models

Florek, M., Sega, E. I., Leveson-Gower, D. B., Baker, J. B., Müller, A. M. S., Schneidawind, D., Meyer, E. H., & Negrin, R. S. (2014) · Blood · doi:10.1182/blood-2014-02-555128 · Cited by 29 · see citing works

Uptake routes of tumor-antigen MAGE-A3 by dendritic cells determine priming of naïve T-cell subtypes

Moeller, I., Spagnoli, G. C., Finke, J., Veelken, H., & Houet, L. (2012) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-012-1272-y · Cited by 28 · see citing works

Comparative Structural and Compositional Analyses of Cow, Buffalo, Goat and Sheep Cream

Felice, V. D., Owens, R. A., Kennedy, D., Hogan, S. A., & Lane, J. A. (2021) · Foods · doi:10.3390/foods10112643 · Cited by 27 · see citing works

RAGE and its ligands in cancer – culprits, biomarkers, or therapeutic targets?

Tesařová, P., Čabiňaková, M., Mikulová, V., Zima, T., & Kalousová, M. (2015) · Neoplasma · doi:10.4149/neo_2015_061 · Cited by 27 · see citing works

Black carp STING functions importantly in innate immune defense against RNA virus

Lu, L., Wang, X., Wu, S., Song, X., Zou, Z., Xie, X., Xiao, J., Chen, S., & Feng, H. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.08.037 · Cited by 27 · see citing works

Immunity and the Emergence of Individuality

Pradeu, T. (2013) · The MIT Press eBooks · doi:10.7551/mitpress/8921.003.0008 · Cited by 27 · see citing works

Nutritional Immunity: Homology Modeling of Nramp Metal Import

Cellier, M. F. M. (2012) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4614-0106-3_19 · Cited by 26 · see citing works

Chapter 7 Cell Protective Functions of Secretory Clusterin (sCLU)

Klock, G., Baiersdörfer, M., & Koch-Brandt, C. (2009) · Advances in cancer research · doi:10.1016/s0065-230x(09)04007-x · Cited by 26 · see citing works

Molecular cloning, characterisation and expression analysis of melanoma differentiation associated gene 5 (MDA5) of green chromide, Etroplus suratensis

Bhat, A., Paria, A., Deepika, A., Sreedharan, K., Makesh, M., Bedekar, M. K., Purushothaman, C. S., & Rajendran, K. V. (2014) · Gene · doi:10.1016/j.gene.2014.12.028 · Cited by 25 · see citing works

Type I NKT ‐cell‐mediated TNF ‐α is a positive regulator of NLRP 3 inflammasome priming

Chow, M. T., Duret, H., Andrews, D. M., Faveeuw, C., Möller, A., Smyth, M. J., & Paget, C. (2014) · European Journal of Immunology · doi:10.1002/eji.201344329 · Cited by 24 · see citing works

CD36 deficiency ameliorates drug-induced acute liver injury in mice

Zhang, C., Shi, X., Su, Z., Hu, C., Mu, X., Pan, J., Li, M., Teng, F., Tao, L., Zhao, T., et al. (2021) · Molecular Medicine · doi:10.1186/s10020-021-00325-z · Cited by 24 · see citing works

The Functional Polymorphism Ala258Ser in the Innate Receptor Gene Ficolin-2 in the Donor Predicts Improved Renal Transplant Outcome

Eikmans, M., Canck, I. D., van der Pol, P., Baan, C. C., Haasnoot, G. W., Mallat, M. J. K., Vergunst, M., de Meester, E., Roodnat, J. I., Anholts, J. D. H., et al. (2012) · Transplantation · doi:10.1097/tp.0b013e31825c5967 · Cited by 23 · see citing works

Molecular characterisation, ontogeny and expression analysis of melanoma differentiation-associated factor 5 (MDA5) from Asian seabass, Lates calcarifer

Paria, A., Makesh, M., Chaudhari, A., Purushothaman, C. S., & Rajendran, K. V. (2017) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2017.09.010 · Cited by 23 · see citing works

Immunoregulatory Role of Myeloid-derived Cells in Inflammatory Bowel Disease

Leal, M. C., & Däbritz, J. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000511 · Cited by 22 · see citing works

Scavenger receptors as regulators of natural antibody responses and B cell activation in autoimmunity

Jordö, E. D., Wermeling, F., Chen, Y., & Karlsson, M. C. I. (2011) · Molecular Immunology · doi:10.1016/j.molimm.2011.01.010 · Cited by 22 · see citing works

Emerging role of ficolins in autoimmune diseases

Wang, P., Wu, Q., & Shuai, Z. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105266 · Cited by 20 · see citing works

Dysregulation of Immune Response Mediators and Pain-Related Ion Channels Is Associated with Pain-like Behavior in the GLA KO Mouse Model of Fabry Disease

Spitzel, M., Wagner, E., Breyer, M., Henniger, D., Bayin, M., Hofmann, L., Mauceri, D., Sommer, C., & Üçeyler, N. (2022) · Cells · doi:10.3390/cells11111730 · Cited by 19 · see citing works

Anti-Pentraxin Antibodies in Autoimmune Diseases: Bystanders or Pathophysiological Actors?

Brilland, B., Vinatier, E., Subra, J., Jeannin, P., Augusto, J., & Delneste, Y. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.626343 · Cited by 15 · see citing works

Black carp RNF5 inhibits STING/IFN signaling through promoting K48-linked ubiquitination and degradation of STING

Yan, J., Qiao, G., Yin, Y., Wang, E., Xiao, J., Peng, Y., Yu, J., Du, Y., Li, Z., Wu, H., et al. (2023) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2023.104712 · Cited by 16 · see citing works

Fluid phase recognition molecules in neutrophil-dependent immune responses

Jaillon, S., Ponzetta, A., Magrini, E. I., Barajon, I., Barbagallo, M., Garlanda, C., & Mantovani, A. (2016) · Seminars in Immunology · doi:10.1016/j.smim.2016.03.005 · Cited by 16 · see citing works

Black carp TRAFD1 restrains MAVS-mediated antiviral signaling during the innate immune activation

Yan, J., Zhang, Y., Tan, Y., Dai, Y., Wei, J., Cao, Y., & Feng, H. (2020) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2020.04.045 · Cited by 16 · see citing works

A RING finger protein 114 (RNF114) homolog from Chinese sturgeon (Acipenser sinensis) possesses immune-regulation properties via modulating RIG-I signaling pathway-mediated interferon expression

Liao, Z., Chen, X., Nie, D., Wang, J., & Wu, M. (2014) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2014.09.030 · Cited by 16 · see citing works

Cloning and functional analysis the first NLRC4-like gene from the sea cucumber Apostichopus japonicus

Chen, K., Lv, Z., Shao, Y., Guo, M. Z., & Li, C. (2019) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2019.103541 · Cited by 15 · see citing works

T Cells and Blood Vessels

Bu, D.-X., & Lichtman, A. H. (2010) · Circulation · doi:10.1161/circulationaha.110.991059 · Cited by 14 · see citing works

Role of TIM-4 in innate or adaptive immune response

Nurtanio, N., & Yang, P. (2011) · North American Journal of Medical Sciences · doi:10.4297/najms.2011.3217 · Cited by 13 · see citing works

Abundant members of Scavenger receptors family and their identification, characterization and expression against Vibrio alginolyticus infection in juvenile Larimichthys crocea

He, J., Liu, H., Yang, J., Dong, X., & Wu, C. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.02.009 · Cited by 13 · see citing works

Pattern Recognition Receptors and the Host Cell Death Molecular Machinery

Amarante-Mendes, G. P., Adjemian, S., Branco, L. M., Zanetti, L. C., Weinlich, R., & Bortoluci, K. R. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02379 · Cited by 759 · see citing works

Review: Soluble innate immune pattern-recognition proteins for clearing dying cells and cellular components: implications on exacerbating or resolving inflammation

Litvack, M. L., & Palaniyar, N. (2010) · Innate Immunity · doi:10.1177/1753425910369271 · Cited by 98 · see citing works

Introduction: the immune response against dying cells

Zitvogel, L., & Kroemer, G. (2008) · Current Opinion in Immunology · doi:10.1016/j.coi.2008.07.009 · Cited by 13 · see citing works

Sensing Necrotic Cells

Miyake, Y., & Yamasaki, S. (2012) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-1680-7_9 · Cited by 73 · see citing works

Pattern Recognition Receptors in CNS Disease

Carpentier, P. A., Duncan, D. S., & Miller, S. D. (2007) · Springer eBooks · doi:10.1007/978-0-387-73894-9_7