Cited by 235Neural dynamics and brain functionFunctional Brain Connectivity StudiesMemory and Neural Mechanisms

Spontaneous and driven cortical activity: implications for computation.

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Ringach, Dario L·2009·Current Opinion in Neurobiology

Abstract

The traditional view of spontaneous neural activity as 'noise' has been challenged by recent findings suggesting that: (a) spontaneous activity in cortical populations is highly structured in both space and time, (b) the spatio-temporal structure of spontaneous activity is linked to the underlying connectivity of the cortical network, (c) spontaneous cortical activity interacts with external stimulation to generate responses to the individual presentations of a stimulus, (d) network connectivity is shaped in part by the statistics of natural signals and (e) ongoing cortical activity represents a continuous top-down prediction/expectation signal that interacts with incoming input to generate an updated representation of the world. These results can be integrated to provide a new framework for the study of cortical computation.

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Authors
Ringach, D. L.
Affiliations
University of California, Los Angeles (US)
Corresponding author
Ringach, Dario L
Venue
Current Opinion in Neurobiology
Publisher
Elsevier BV
Published
2009-08
Volume
19
Issue
4
Pages
439-444
ISSN
0959-4388 (ISSN-L)
OpenAlex
W2148439693
Cited by
234
References
50
Citations by year
2026: 7 · 2025: 16 · 2024: 11 · 2023: 29 · 2022: 14 · 2021: 21 · 2020: 8 · 2019: 13 · 2018: 14 · 2017: 18 · 2016: 15 · 2015: 17 · 2014: 7 · 2013: 13 · 2012: 16
FWCI
0.78
Type
journal article
Language
en
Open access
Locations
  • Current Opinion in Neurobiology (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health
  • National Eye Institute (R01EY018322, EY-12816, EY18322, R01EY012816)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords
spontaneous neuronal activity, cortical activity, cortical connectivity, spatiotemporal structure, top-down prediction, expectations, cortical computation, noise
MeSH terms
Animals, Cerebral Cortex, Models, Neurological, Nerve Net, Neurons, Photic Stimulation, Visual Perception, Neural Networks, Computer

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